Npan072502.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nemotelus pantherinus
Gene Symbol
ZNF219
Assembly
GCA_963978885.1
Location
OZ022266.1:65659257-65665540[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 8e-06 0.0021 20.5 1.6 1 23 105 127 105 127 0.97
2 16 2.2e-05 0.006 19.1 0.3 1 23 133 155 133 155 0.98
3 16 4.4e-05 0.012 18.2 4.6 1 23 159 181 159 182 0.96
4 16 5.4e-06 0.0014 21.1 4.7 1 23 187 209 187 209 0.99
5 16 0.0066 1.8 11.3 1.3 1 23 215 237 215 237 0.98
6 16 0.00023 0.062 15.9 3.8 1 21 245 265 245 266 0.96
7 16 0.46 1.2e+02 5.5 0.3 1 21 278 299 278 302 0.89
8 16 0.0012 0.33 13.6 0.2 1 23 309 331 309 331 0.96
9 16 1.6e-06 0.00042 22.7 0.3 1 23 337 359 337 359 0.98
10 16 0.0016 0.43 13.2 3.3 1 23 369 391 369 391 0.99
11 16 4.7e-05 0.012 18.1 1.2 1 23 397 419 397 419 0.98
12 16 0.49 1.3e+02 5.5 0.2 1 21 485 506 485 509 0.89
13 16 2.2e-06 0.00058 22.3 1.7 1 23 516 538 516 538 0.96
14 16 0.062 17 8.3 3.2 1 23 544 566 544 566 0.98
15 16 0.23 60 6.5 2.1 1 23 579 601 579 601 0.92
16 16 1.8e-05 0.0049 19.4 0.2 1 23 607 629 607 629 0.99

Sequence Information

Coding Sequence
ATGAGTGATTTGGATGATTTATCCTTTGCGTGCAAAAAAGTTATATCTGTAAAAGAGGAAGTTGAAATCTGCGAAACACAGTTACTAGAACAGATTTTCGATGGATTCGAAGTGACACATGTAGACCCTTGTgttaaaatcgaaaaagaaattggAGTTGTAAACGAAATATTCCACACAGAAGATAATCAAACCGAATTAAACGATTGTGAAGGGATTAGGGAGCAACCATACGAGTGCTACTTACGACCGGATAATTCCACCAGTTCAGCTCGAAAACATGAAGATATTAGGCCGTCGTTGAAAAATAATCATATATGCTCGATTTGTGCGAAATCATTCAGGTCGAGTTCAAGGCTTAAAGTGCATATGAATGTTCATACTGGCAGTCAGCCGTATGCATGCACAATATGCCCTAGAAAGTATGCCAGTCATGATGGCCTACGCGCGCACATTTTAACTCACGGTTCCGGGTTCAAATGTACGTTTTGTGAAAAGTCTTACAAATCCAGATCCGGAATGAATAAGCACATTAAAATTCATCATGGCGAACGTAATTTCCAGTGTGAAATCTGTTCCAAATCATTCACGAGCAAGTATCTACTCTCGTCACACCACAAAACGCATTcggataaaaagaaatatgagtGCACGTTGTGCAGTGAAAAATTCGCAGAGAATAGCAAGCGCCTTAGGCACGAAAAGACGCACACAAATAACCATAGTAATTACCATGAATGTGAAAACTGTAAAAAGTGTTTTAGATCAGAGGACCAGTATCGTAGCCATATGAAAGGTAAAAGGTGCATAGGATATGTTTCAGAAAAGCTATTCAAATGTTCCAAGTGTGAAAATGAATCATTCGTAAGCATTGAGCTCCTAAACCAGCACAAAGTCGAAGTTCATCCGCCCCCGAAAAAAAACCATGCATGCTCAGTTTGTGCGAAAGCCTACAGGTATGATGCTGAACTTCGGGTGCATATGAACATTCATACTGGCAAGCGGCCGTACGCATGCACAATATGTTCAAAGGCGTTCACCTGGCCCAGTAACTTACGCAAACACATGTTAACTCACAGCGCAGAGGCGAAGAATCGCTCCACGTTCAAATGTACACTCTGCGAAAAGCTTTGTAGTTCAAGAGGCCGACTGAATAGTCACATGAATATGCATCGAGGCGAACGTCCTTTCAAGTGCGACACCTGTCCCAAAACGTTTATGAGCCCAGATACACTCTCGTCACACAAAAAACTGCATGCAGATGATAGGGAAAATGAGTTATGCAATCAAAAATTTACAGGCAATAACAAGCGGCGTAAGCTCGAGAAGCTGCACAAAAATAGCAGCATGAAGTATTGTTGTGCAAAATGTAAAAAGTATTTTAGATTCGAACACCAGCACCGCACCCATTTGGAAGATAATAAATGCAAGGGATATGCTTCAGAAAAGCCATTTCAATGTTCTAAGTGTGAAAATGAATCATTCGTAAGTATTGAGCTCCTAAATCAACACAAAGTTGAAGTTCATCCACCcccgaaaaaaaatcatgcatgCTCGATTTGTGAGAAATCATTCAGGTCGAGTTCAAGGCTTAAAGTGCATATGAACGTTCATACCGGCAATCGACCGTATAAGTGCACAGTGTGTCCTAAAAAGTACGGCTGCCCCCAGAGCTTACGCTATCACAAGTTAACTCACAGCTTATTAAGCGCAGATAGGAAGATTCGTGGCAGATTCAAATGTACGCTCTGTGAAAAGTCTTACTTATCAAAAATCGGTCTGAATAGTCACAAGTATTTTCATCGTGGCGAACGTCCTTTCAAATGCGAATTATGTCCCAAGTCATATACGAGCGCAACATCACTCGGATCACACATTATTACGCATTCTGTTTATTATGGTGAGGTCATCCTCGCTTGCCGAACGAACTGGCAGAAAGCAGACCTGGAGCATCAGCGAGTGTTGGAAGACCAGACTGCTGAGCCAGCTACTCCTGTAGGGGTCCCAGGACTGGATCGGCCACGGCAGAATAGGCGCGTGGCCGAGTCTAGTCGTGAAGACACACAAGAAACCCGGGTCAGGAAGGAGGTTCCAGCACCCGATTTAAGGAGGTGGGTGACGGTCACCCACAGAAAGAAGAAGATGAACGTCGCTAAACCGCCGGTGGTACCCACTGGCCCAGAAAAGGTGCAGAAAAAAGGGTTACCAAAGGGCGAAAACAAAGAAACagtggaaaagaaaaagaagggAAAGAATAGGCAGAGACAGCGGGGAAAGAAAATTGATGCTGTCATCGTCAAACCAGCTCCGGGAAAAACCTACGCGGAGTTCCTGGGGGCCATCCGTCAAAATGTTTCCCCAGTTGAAACTGGTACACAAGTACGACGCATAAGGAAAACTGCAGAAGGAGGGGTCCTTCTGGAAATTGCGCGGACGAATGATCGAACGAAATTGCAGAACTCGATCCAggctgccgtagatggccagggggcgtga
Protein Sequence
MSDLDDLSFACKKVISVKEEVEICETQLLEQIFDGFEVTHVDPCVKIEKEIGVVNEIFHTEDNQTELNDCEGIREQPYECYLRPDNSTSSARKHEDIRPSLKNNHICSICAKSFRSSSRLKVHMNVHTGSQPYACTICPRKYASHDGLRAHILTHGSGFKCTFCEKSYKSRSGMNKHIKIHHGERNFQCEICSKSFTSKYLLSSHHKTHSDKKKYECTLCSEKFAENSKRLRHEKTHTNNHSNYHECENCKKCFRSEDQYRSHMKGKRCIGYVSEKLFKCSKCENESFVSIELLNQHKVEVHPPPKKNHACSVCAKAYRYDAELRVHMNIHTGKRPYACTICSKAFTWPSNLRKHMLTHSAEAKNRSTFKCTLCEKLCSSRGRLNSHMNMHRGERPFKCDTCPKTFMSPDTLSSHKKLHADDRENELCNQKFTGNNKRRKLEKLHKNSSMKYCCAKCKKYFRFEHQHRTHLEDNKCKGYASEKPFQCSKCENESFVSIELLNQHKVEVHPPPKKNHACSICEKSFRSSSRLKVHMNVHTGNRPYKCTVCPKKYGCPQSLRYHKLTHSLLSADRKIRGRFKCTLCEKSYLSKIGLNSHKYFHRGERPFKCELCPKSYTSATSLGSHIITHSVYYGEVILACRTNWQKADLEHQRVLEDQTAEPATPVGVPGLDRPRQNRRVAESSREDTQETRVRKEVPAPDLRRWVTVTHRKKKMNVAKPPVVPTGPEKVQKKGLPKGENKETVEKKKKGKNRQRQRGKKIDAVIVKPAPGKTYAEFLGAIRQNVSPVETGTQVRRIRKTAEGGVLLEIARTNDRTKLQNSIQAAVDGQGA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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