Basic Information

Gene Symbol
ZFY
Assembly
GCA_946902865.1
Location
CAMPPV010000532.1:245353-249756[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 32 0.0077 0.58 11.6 0.0 2 23 184 205 183 205 0.97
2 32 1.2e-05 0.00091 20.4 1.1 1 23 211 234 211 234 0.95
3 32 1.8e-06 0.00014 23.0 0.5 1 23 245 267 245 267 0.98
4 32 1.8 1.4e+02 4.1 0.3 1 12 273 284 273 288 0.88
5 32 2.6 2e+02 3.7 0.1 9 23 314 328 312 328 0.92
6 32 8.6 6.5e+02 2.0 0.3 3 12 336 345 335 349 0.88
7 32 2.6 2e+02 3.7 0.1 9 23 356 370 354 370 0.92
8 32 8.6 6.5e+02 2.0 0.3 3 12 378 387 377 391 0.88
9 32 2.6 2e+02 3.7 0.1 9 23 398 412 396 412 0.92
10 32 8.6 6.5e+02 2.0 0.3 3 12 420 429 419 433 0.88
11 32 2.6 2e+02 3.7 0.1 9 23 440 454 438 454 0.92
12 32 8 6e+02 2.1 0.2 3 12 462 471 461 475 0.88
13 32 2.6 2e+02 3.7 0.1 9 23 482 496 480 496 0.92
14 32 1.8 1.4e+02 4.1 0.3 1 12 502 513 502 517 0.88
15 32 2.6 2e+02 3.7 0.1 9 23 524 538 522 538 0.92
16 32 1.8 1.4e+02 4.1 0.3 1 12 544 555 544 559 0.88
17 32 2.6 2e+02 3.7 0.1 9 23 566 580 564 580 0.92
18 32 1.8 1.4e+02 4.1 0.3 1 12 586 597 586 601 0.88
19 32 2.6 2e+02 3.7 0.1 9 23 608 622 606 622 0.92
20 32 1.8 1.4e+02 4.1 0.3 1 12 628 639 628 643 0.88
21 32 2.6 2e+02 3.7 0.1 9 23 650 664 648 664 0.92
22 32 1.5 1.1e+02 4.4 0.2 1 12 670 681 670 685 0.84
23 32 2.6 2e+02 3.7 0.1 9 23 692 706 690 706 0.92
24 32 8 6e+02 2.1 0.2 3 12 714 723 713 727 0.88
25 32 0.98 74 5.0 0.1 9 23 734 748 732 748 0.92
26 32 0.00032 0.024 16.0 0.2 1 23 754 776 754 776 0.98
27 32 0.0004 0.03 15.7 0.3 1 23 782 804 782 804 0.93
28 32 0.00034 0.025 15.9 0.9 1 23 810 832 810 832 0.97
29 32 4.2e-05 0.0032 18.7 0.8 1 23 838 861 838 861 0.96
30 32 0.0097 0.74 11.3 0.0 2 23 891 912 890 912 0.95
31 32 8.3 6.3e+02 2.1 0.8 5 23 924 943 918 943 0.86
32 32 0.096 7.2 8.2 3.9 1 23 952 975 952 975 0.96

Sequence Information

Coding Sequence
ATGTTGCATTTCGATAGCGCAACGTGTCGCGTATGCCTCGCGATATGCGGCGACATAGTGCCTATATTCGAGAGCACGGACTCTGGTGCTTTACAGTTGCGAGAGAAACTAGAGTTCGTGACACGCACGGAGCTCTGCCGGCACGCGGCTCTGCCGCGGGGCCTGTGCGGAGCTTGCCGGGCCGCCCTCGACTCCGCCTATGCACTCGCCGCCCGCTGCATAGCCGCCGAGACCATGTTCGCAAGAGCCATCAAGTCGGAGGACTGTGTCAAAGTAGAGTGCGAGAGTTCTACGGGAGAGCGAGTGGCGCGTCCGGCTCGGAGCGATAGTGAGGAGAGTGACGGCGCCGGACTGGACTTCGCTCCCACCATCCCCGCTGAGGCCAGTCTCAAATATCAATTAAACGGTGGTGACCCACATTTTCAGGATGACGCGCATGCCGCTTCTTCTCCTGAGTGCACGCTCCAAGTGAAGAAAGTGAAACATAGAAAAAAGCGGAAGAAACGTTTGGGAAGCGAAGCGGCGGCGGCGGCCGGTGCCGGCGGGTGGGTGTGCGGCGTGTGCGGGCTGGCGGCGCGCGCGCCCTCCGCCCTGCACATCCACATGAGGAAGCACACGGGGGAGCGGCCATACGCGTGCGCGCACTGCGGGCGCACGTTCTCGCAGAAGGGCACGCTGGCCAAGCACACGGCGAGCCGGCACGGTGCGCCGCGCGCGCCGCCCCCGCCCGCCTTCACCTGCGAAGTGTGCGGCAAGCGGTTCGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCATACGCCTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACTCTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTTGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTCCGACTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTCCGACTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACGGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTCCGACTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCCTCACACTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTCCGCCTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGTGAGTCCCCGTACGCCTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTACGCCTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTACGCCTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGATTCGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTACGCCTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACGGTACACCTGCGTGTGCACACCGGCGAGTCCCCGTACGCCTGCAACTACTGCCCAAGCACATTCAGGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTCGTGCGCAAGCGCGACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTCCGCCTGCAACTACTGCCCGAGCACATTCAAGCAGGTCACTCTCAACCTCTTCACACTGCAGACAGGGTTCGTGCGCAAGCGCAACGTCACCGTACACCTGCGCGTGCACACCGGCGAGTCCCCGTACGCGTGCAACTACTGCCCGAGCACATTCAAGCAGGTGGGGCCGCTGATCCGACACCGGCGCATTCACACCGGCGAGAAACCCTTTCTCTGCGCGCAGTGCCCCAAGCGGTTCAAGGACAAGACGTCGCTCGCAGCGCACGCGACCTCGCACAGTGACGAGCGCCGCTTCGCCTGCGCGCTCTGCGGCAAGCGCATGAAGACCAACAACTCGCTGCGCAAGCACATGGAGCGGCACGCGGACGGCAGGAAGCACGTGTGCGACCGCTGCGGCCGCGCGTTCGCCCTAAAGGGTAACCTCAAGATGCACATGCTGCGCCAGCACTCGGAGCGGGCGGGCGTGTGCGGCGTGTGCCGCAAGCCCGTGCCCGACGCGGCCGAGCACGCGCGCCGCCACACCGGCCAGCTGCTGCCGTGCGCGCAGTGCGGCCGCCGCTTCCTGCGCGCCGCCGGCCTGCGCGCCCACCTCGCGCGCCACGCGCGCGCCGGCGCGCACCCGTGCGCCGCGCCCGCCTGCCGCGCCGCCTTCCCCACCCTCGCCATGCTGCACCACCACACCGCCAAGCTCCACCGCCCGACACCCTACACGCCCCCGCACCCCTGCGCGCACTGCTCCCGTGCCTTCCTCCGCCTCTGCGACCTCACCAAACACTTGAAGATTGCTCACAACATTTTGAAGACAGAGCGGGTCGACCGATCTTAG
Protein Sequence
MLHFDSATCRVCLAICGDIVPIFESTDSGALQLREKLEFVTRTELCRHAALPRGLCGACRAALDSAYALAARCIAAETMFARAIKSEDCVKVECESSTGERVARPARSDSEESDGAGLDFAPTIPAEASLKYQLNGGDPHFQDDAHAASSPECTLQVKKVKHRKKRKKRLGSEAAAAAGAGGWVCGVCGLAARAPSALHIHMRKHTGERPYACAHCGRTFSQKGTLAKHTASRHGAPRAPPPPAFTCEVCGKRFVRKRDVTVHLRVHTGESPYACNYCPSTFKQVTLNLFTLQTGFVRKRDVTVTLNLFTLQTGFVRKRDVTVHLRVHTGESPSDCNYCPSTFKQVTLNLFTLQTGFVRKRDVTVHLRVHTGESPSDCNYCPSTFKQVTLNLFTLQTGFVRKRDVTVHLRVHTGESPSDCNYCPSTFKQVTLNLLTLQTGFVRKRDVTVHLRVHTGESPSACNYCPSTFKQVTLNLFTLQTGFVRKRDVTVHLRVHTGESPYACNYCPSTFKQVTLNLFTLQTGFVRKRDVTVHLRVHTGESPYACNYCPSTFKQVTLNLFTLQTGFVRKRDVTVHLRVHTGESPYACNYCPSTFKQVTLNLFTLQTGFVRKRDVTVHLRVHTGESPYACNYCPSTFKQVTLNLFTLQTGFVRKRDVTVHLRVHTGESPYACNYCPSTFRQVTLNLFTLQTGFVRKRDVTVHLRVHTGESPSACNYCPSTFKQVTLNLFTLQTGFVRKRNVTVHLRVHTGESPYACNYCPSTFKQVGPLIRHRRIHTGEKPFLCAQCPKRFKDKTSLAAHATSHSDERRFACALCGKRMKTNNSLRKHMERHADGRKHVCDRCGRAFALKGNLKMHMLRQHSERAGVCGVCRKPVPDAAEHARRHTGQLLPCAQCGRRFLRAAGLRAHLARHARAGAHPCAAPACRAAFPTLAMLHHHTAKLHRPTPYTPPHPCAHCSRAFLRLCDLTKHLKIAHNILKTERVDRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-