Basic Information

Insect: Nematopogon swammerdamellus
Gene Symbol: tfap2e_1
Assembly: GCA_946902865.1
Location: CAMPPV010000096.1:154876-208562[+]

Transcription Factor Domain

TF Family: AP-2
Domain: TF_AP-2 domain
PFAM: PF03299
TF Group: Basic Domians group
Description: Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 7e-24 2.4e-19 70.9 0.0 1 45 400 444 400 451 0.97

2 2 2.4e-54 8.3e-50 170.3 0.0 45 196 648 796 643 797 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	7e-24	2.4e-19	70.9	0.0	1	45	400	444	400	451	0.97
2	2	2.4e-54	8.3e-50	170.3	0.0	45	196	648	796	643	797	0.96

Sequence Information

Coding Sequence: ATGTGGTCGCCGCCGCGCCGGCCCGCGCCCATCAATAGACATCGATGCGCGCGACCTCTGAAGCGCTCGCTCGCTGCCACCGCCCCTACACGCCCTCCGGCGGGCGGCGCCCGGGGCGGCGCGCGGCGCGCCGGGGGCGGGCGGGCGCGCGACGCCCAGGGCGGCGCGCGGCGCGTCGCCAGTCCGCCGCGCAGCGCCGCCGAGCTAGCGCGCGCACCAGCGTGCACGGTTGCTCTAGACGCGCCGAAGCAATTCGGCGCGTACCGTCTTGAGAATAAAGGTGAAATTCCAACGCTGGCGCTGGCGTACGTCGACCTTTCCAGTGTCATCGAGGTGCAGGAGCGGCTGGGCGGCGGCGGGCTGGGTCTGGGCGGCGGCGGGTTCGGCCGCGGCGGCGCGCAGCCCTCGCTCGCGGACTTCCAGCCGCCCTACTTCCCGCCGCCCTTCGCGCCCGCCCCCCACGTGCCGCACCCCACAGCACCCTCGCCGCACCATCAGCAGCAGAGTCATGGCATGGAGTACGGCGGCGGTGGCGGCGCGGGCGGCGGCGGGGGCGGCGCGGGCGCAGAGTACGCGCAACACTATGCGCCGCAGCAGCTGCTGCCGCGCCACCACGCGCACGACGCGCACGCGCACCTGCGCCACCACCGCGACCACCACGACGCGCTCCATCCGCACCACACAAGCGGTGTTCGAGCGGCTGAGGCTTGGGGTAAGGTAGCGGTGAGGCAGAGCGCAGAGTCGAGCGGTAGAGGGGAGCGCGCGCGGGGCGGGAAGCGTGTGCGAGACGGTCTGGCGGCCGGTGTGGGGAGCTCACGCGGGGCGGGAATCGTGCGGGAGAGAGGCAAGGGACGAGGCGCGATCGCAGCAGGCAGGCGACGACTGCGCGCTGCGGCCTCTCGCGCTCGACTAAGAGACTTGAGGATCGTGAACCGCAACTCGGTGGAACATTTATCGCACGGCGGGTTCGGCTACTCGGGCGGGGGTGAGAGGCGCGGGGAGTACGGCGCGCGGGGAGAGGGGCACGAGCTGGCGCTACAACACGCGCTACACGCCGCCGCCGCCGCCGAGGATCCTAGATCGAGACGCATCCAAGTGGACGCCCGCCGCGGCGGCGCGGCGGCGGCGCGGCGCGGCGGACCCATGAAGGGTCGTGAGTGCGGCGGCGGGGGCGGGAGTTGCGCACCCAGCGACGTGTTCTGCTCGGTACCCGGGCGGCTCTCGCTGCTCTCCTCCACCAGCAAGTACAAGGTGACAGTCGCCGAGGTGCAGCGGCGGCTATCCCCGCCCGAGTGTCTCAACGCCAGTCTGCTGGGCGGTGTGTTAAGGAGGCTAGAAGCTAATGATGACGACAGACACGCGCCGCCGCTGCTGTGCGCCGCGTTCGGTTGGCCGTCGCTCGAGTCGCCCCCCTCCCCGAATCTACGGGATCATTCTTCTGAACACGAGATTTTGGCGCCACGTCAATCTATGCGCGCTCTAAGTGACCAGACCGCGGCGGTGCGGAGGAGGCGGGGCGGCGCGGCGGGCGCGCCGGCCGGGTTGAATGTTCGCTATAACACCGCACCGCACCGCGCTGTTGCGCCCCCGCGCCGCCCCGTGTCGGCATCGCACGCTGCTATCAAAGGAGACGCGGGCGCGGCGGGCGGGCGGCGCGCCGCGATGCCGCCCGGTGGCGGCATCGTGCGCTGCCATCAAAGGACGCCGCGCGGGCGCGGCGGGCGGCGCGGGCGCGGAGGGCGGCGCGCCGCGCTGCCTGTATGCGACCGACCTGCATTGCGCTTCAGTCCAGCCGGTCACGCGGCGCGGAAGATCAATGTGTGTCAGTCGACGCGAGCAGCTGCAGGCAGGAGCTCTATAGCTACCCCCGAGTCAGCTCGGGCGGCGGCGCGCGAGGTGCGGGGCGGGGCGGAGCGGGGAGACACGGCTAGAGACATTGCGAAAGCGAAGAGTAAGAACGGCGGGCGGCTGCTTCGGGAGAAGCTGGAGAAGATCGGTCTGAACCTGCCGGCGGGGAGGCGGAAGGCAGCCAACGTCACCCTCCTCACCTCGCTCGTCGAAGCGGAAGCAGTGCACCTGGCGAGAGACTTCGGCTACGTGTGCGAGACGGAGTTTCCGGCGCGCGCGCTCGCGGAGTACCTGGCGCGGCAACACGCCGAGCACGACGCGCGCAGACGCCGCGACCTGCTGCAGGCCACCAAGCAGatAATGAAGGAGCTGATGGATCTGCTGAACCAGGACCGCTCGCCGCTGTGCAACACGCGGCCCCCGCACCTCCTCGAGCCCGCCATCCAGCGACACCTCACGCACTTCTCCCTCATCTCGCACGGCTTCGGCGGACCGGCCATCGTCGCCGCCCTCACAGCCATACAGAACTTTCTAAACGAATCCCTGAAGCACATAGACAAGCTGTACCCCGCAGGCGGCGGCGGAGGCGGCGGCATGGTGTCCTCGTCCATGGACAAAACCAAGATGGACCCCGACATCAAGAAGTAA
Protein Sequence: MWSPPRRPAPINRHRCARPLKRSLAATAPTRPPAGGARGGARRAGGGRARDAQGGARRVASPPRSAAELARAPACTVALDAPKQFGAYRLENKGEIPTLALAYVDLSSVIEVQERLGGGGLGLGGGGFGRGGAQPSLADFQPPYFPPPFAPAPHVPHPTAPSPHHQQQSHGMEYGGGGGAGGGGGGAGAEYAQHYAPQQLLPRHHAHDAHAHLRHHRDHHDALHPHHTSGVRAAEAWGKVAVRQSAESSGRGERARGGKRVRDGLAAGVGSSRGAGIVRERGKGRGAIAAGRRRLRAAASRARLRDLRIVNRNSVEHLSHGGFGYSGGGERRGEYGARGEGHELALQHALHAAAAAEDPRSRRIQVDARRGGAAAARRGGPMKGRECGGGGGSCAPSDVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRLEANDDDRHAPPLLCAAFGWPSLESPPSPNLRDHSSEHEILAPRQSMRALSDQTAAVRRRRGGAAGAPAGLNVRYNTAPHRAVAPPRRPVSASHAAIKGDAGAAGGRRAAMPPGGGIVRCHQRTPRGRGGRRGRGGRRAALPVCDRPALRFSPAGHAARKINVCQSTRAAAGRSSIATPESARAAAREVRGGAERGDTARDIAKAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEAEAVHLARDFGYVCETEFPARALAEYLARQHAEHDARRRRDLLQATKQIMKELMDLLNQDRSPLCNTRPPHLLEPAIQRHLTHFSLISHGFGGPAIVAALTAIQNFLNESLKHIDKLYPAGGGGGGGMVSSSMDKTKMDPDIKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -