Basic Information

Insect: Nemapogon koenigi
Gene Symbol: ZEB2
Assembly: GCA_963924495.1
Location: OZ004639.1:11341260-11359809[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0013 0.092 13.8 1.6 1 23 261 283 261 283 0.99

2 14 0.0014 0.099 13.7 1.1 1 23 290 313 290 313 0.94

3 14 0.0035 0.25 12.5 0.6 1 23 317 339 317 339 0.98

4 14 5.5e-05 0.0038 18.2 0.2 1 23 344 367 344 367 0.97

5 14 0.072 5 8.3 0.2 1 23 371 394 371 394 0.95

6 14 0.056 3.9 8.7 0.1 3 20 406 423 405 425 0.96

7 14 0.00019 0.013 16.5 0.1 3 23 435 455 435 455 0.99

8 14 0.025 1.7 9.8 0.3 3 21 482 500 481 505 0.92

9 14 0.0015 0.1 13.7 0.6 3 23 511 531 511 531 0.98

10 14 0.054 3.8 8.7 0.7 3 23 548 568 546 569 0.94

11 14 0.00049 0.034 15.1 0.3 2 23 586 607 585 607 0.96

12 14 0.0023 0.16 13.0 1.5 1 23 613 635 613 635 0.94

13 14 7.9e-06 0.00055 20.8 3.0 1 23 640 663 640 663 0.97

14 14 0.08 5.5 8.2 4.1 1 23 669 692 669 692 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0013	0.092	13.8	1.6	1	23	261	283	261	283	0.99
2	14	0.0014	0.099	13.7	1.1	1	23	290	313	290	313	0.94
3	14	0.0035	0.25	12.5	0.6	1	23	317	339	317	339	0.98
4	14	5.5e-05	0.0038	18.2	0.2	1	23	344	367	344	367	0.97
5	14	0.072	5	8.3	0.2	1	23	371	394	371	394	0.95
6	14	0.056	3.9	8.7	0.1	3	20	406	423	405	425	0.96
7	14	0.00019	0.013	16.5	0.1	3	23	435	455	435	455	0.99
8	14	0.025	1.7	9.8	0.3	3	21	482	500	481	505	0.92
9	14	0.0015	0.1	13.7	0.6	3	23	511	531	511	531	0.98
10	14	0.054	3.8	8.7	0.7	3	23	548	568	546	569	0.94
11	14	0.00049	0.034	15.1	0.3	2	23	586	607	585	607	0.96
12	14	0.0023	0.16	13.0	1.5	1	23	613	635	613	635	0.94
13	14	7.9e-06	0.00055	20.8	3.0	1	23	640	663	640	663	0.97
14	14	0.08	5.5	8.2	4.1	1	23	669	692	669	692	0.92

Sequence Information

Coding Sequence: ATGAAGGGCGTATTGGTCTGCAAAACTTGTTTGATTACAAATGTGAAAATGTTCCATTTAGATATTCTTGCTAATGCTTATTCAGAACTAACTGGATTGCAATGTAATGAAACAACAGAATATGTGTGTTACGAGTGTGCTGCTCTATTGCTCAAATATCAACAATTTCGCACAAAATGTTTGCAAGCTAACCAAGTGATCTCAgaatttgttagaaaatattgtaAGtTAACAGAGAATGCTGTAAGTATGATTGACCGTAAATTGCATAACCTTGAATCAACAATtatgaaatttgaaattaaagaaaatatttttaatgaaatttacaATGAAtccaaatttaatgaaaatgatAATGAAGTACCTGTGCAATCTATTAAAATGGAAATTGATGATGTAATTAAAGATGAACCTAGTGAAAATAAAGATAAAGTAGAATTATATGATGAAGATCAAGTTGTGTCACATGGAAATGAGTCTTTACATGAGTCTCTAAATGAAGATGATACAAGTGTGGATGAAGGCACCATAATATTTATGGTTACCAATGAAACAGATGATGAAAACACAAAATATGAGAAAATTATGGGATCACCAACTAATAAATTAGATCAAGAAAGTGTTGAGgaaggaaaaaataattcaagTACAGGAACCTTAACTAAAAGAGATTATAGTTTAATGGAAGAATATGTTACAATTGTGAATTTAACACCAGAAGAAGCCAAGAAGGAAGTACTTTTAAGGAAGGAGTCGGGTAACTACAAGAAAAATCCTTACAAATGTGATTTGTGTTACAAAGGATATGGGACACTTCAAACATATGAAAACCATATGAAGAGACATAACaagGATATTGGAGATCATGTTTGTGACTATTGTCACGTAACGTTTTCACTAAAGGCGAATCTAAGTGGCCACATAGGAAAAGGTCACAGCTATAAATTTTACTGCAAATTATGTCCTTACGCTTGTGCCTCTCCTAGCCAAGCAACTATCCATGTAAATAAGCACAAAGGCAAGAAATATCCTTGTGAAGAATGTGGGCTGATTTTCAGTATGCCAAACAGTCTCAGTACGCACCAACGTTACAAACATACGACAGAGTTCGCGTGCGCACTGTGTGGGACTGTATTTGGTAAAGAACGAGGTATCATGCATCATATATCTAGGGTACACAAAGAGgaTACAAACGAACAGAAAGGTCCACTGTGTGAAGAATGTGATGTACATTTTGCAACTGAAACTGCTTGGAAGAGACATTTGGTGCTCTCATCTAAACATACTGTCAGCAACGGGTGTGATGTGTGCGGCGAAACTTTTGAGAGTGTAAACGCGTTGAAGAGACACGCTAGAGTACACCGGAAGGGTCATGATTTGAATAAATCCAAAAGGCGCATCGATTGTACATTGGAAACAAACGGCGGGAAAGGTCGAATGTGTGAAGAATGTGATGTATATTTTACAACTGAAAGGGCTTGGAAGAGGCATTTGGCGCGCTCTTCTAAACATGCTGTCAGTATTGGTTGTAAGGTGTGCAACGAAACTTTTGAGAGTACAGACGCGTTGAAGAGCCACTCTAAAATACATCCAAAGACTCGTGCTATGTATAAACCCAAGCCCAAAAAGCAAATCGATTGTACATTGtGTAAACAAACGGTGATTGGCAGAGATCAATATTATGCACACATGAAAGAACATCATCCAGAAGCGCCACTCCATAGAGAAGTGTTCAACAGACCGCGGAAGTGTGTATGTGAAGCTTGTGGGAAAGGGTTTGCGAATGTGGTACTCCTTAAATACCACCAAAGGATACATACCGGTGAAAAGCCGTTTCCTTGTCCGCAGTGTGATAAGAGTTACAAAATGCAGGAATCATTGACATGTCACCTCGTGTCACATTCGTCTGTGCGTCACAAGTGTCACATGTGTGACCAAACCTTCGTGTATCCGAATTCACTTAACAAGCATATTAAGGTAGTCCACCTCGGTATCCGCCCCTACAAGTGTGATTATTGCGAGAAAACGTATCCGAGCCGCTGTGAAGCTAAGTATCATGCTCAACATGTCCATCTCAAGACTCTAACTTGGCCCAAACGGGATCGTAGTAAAAGGAAGAAAAGTGCTCGTGACTCTGTGACATCGTAA
Protein Sequence: MKGVLVCKTCLITNVKMFHLDILANAYSELTGLQCNETTEYVCYECAALLLKYQQFRTKCLQANQVISEFVRKYCKLTENAVSMIDRKLHNLESTIMKFEIKENIFNEIYNESKFNENDNEVPVQSIKMEIDDVIKDEPSENKDKVELYDEDQVVSHGNESLHESLNEDDTSVDEGTIIFMVTNETDDENTKYEKIMGSPTNKLDQESVEEGKNNSSTGTLTKRDYSLMEEYVTIVNLTPEEAKKEVLLRKESGNYKKNPYKCDLCYKGYGTLQTYENHMKRHNKDIGDHVCDYCHVTFSLKANLSGHIGKGHSYKFYCKLCPYACASPSQATIHVNKHKGKKYPCEECGLIFSMPNSLSTHQRYKHTTEFACALCGTVFGKERGIMHHISRVHKEDTNEQKGPLCEECDVHFATETAWKRHLVLSSKHTVSNGCDVCGETFESVNALKRHARVHRKGHDLNKSKRRIDCTLETNGGKGRMCEECDVYFTTERAWKRHLARSSKHAVSIGCKVCNETFESTDALKSHSKIHPKTRAMYKPKPKKQIDCTLCKQTVIGRDQYYAHMKEHHPEAPLHREVFNRPRKCVCEACGKGFANVVLLKYHQRIHTGEKPFPCPQCDKSYKMQESLTCHLVSHSSVRHKCHMCDQTFVYPNSLNKHIKVVHLGIRPYKCDYCEKTYPSRCEAKYHAQHVHLKTLTWPKRDRSKRKKSARDSVTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -