Nkoe021447.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nemapogon koenigi
Gene Symbol
ZNF296
Assembly
GCA_963924495.1
Location
OZ004655.1:3079037-3091710[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.042 2.9 9.1 0.2 3 23 78 98 76 98 0.97
2 19 0.00039 0.027 15.5 1.8 1 23 161 183 161 183 0.99
3 19 3.3e-06 0.00023 22.0 0.2 1 23 189 211 189 211 0.99
4 19 0.0059 0.41 11.8 1.6 3 23 218 239 216 239 0.92
5 19 0.019 1.3 10.2 7.0 2 23 401 422 400 422 0.97
6 19 0.00012 0.0081 17.1 3.3 1 23 428 450 428 450 0.98
7 19 0.022 1.5 10.0 7.4 1 23 501 523 501 523 0.97
8 19 0.0026 0.18 12.9 1.1 2 23 531 552 530 552 0.97
9 19 0.00013 0.0091 17.0 2.5 1 23 558 580 558 580 0.96
10 19 0.00012 0.0084 17.1 1.8 1 23 586 608 586 608 0.97
11 19 0.0034 0.24 12.5 2.1 1 23 617 639 617 639 0.98
12 19 0.00073 0.05 14.6 2.2 2 23 685 706 685 706 0.97
13 19 0.00038 0.026 15.5 4.4 1 23 727 749 727 749 0.99
14 19 2.4e-05 0.0017 19.3 1.0 1 23 755 777 755 777 0.97
15 19 1.8e-06 0.00012 22.9 3.2 1 23 783 806 783 806 0.98
16 19 0.00013 0.0093 16.9 2.0 2 23 915 936 915 936 0.97
17 19 0.00038 0.026 15.5 4.4 1 23 957 979 957 979 0.99
18 19 1.1e-05 0.00074 20.4 0.8 1 23 985 1007 985 1007 0.97
19 19 0.0002 0.014 16.4 5.4 1 23 1013 1036 1013 1036 0.98

Sequence Information

Coding Sequence
ATGGAACAACCTTTGGAGACCAATAAACCAGAAAATGAAGTCAAAGACTTGAAAATAATAGAACCGGAGGCATCAAGTGAGGAACCGAAGCCAAAAGTTTTTGAAAtaagtgaaaactgtattctAACTCCTGAAGCAATAGTGAGCACAAAAACCATACTGAACAACATAGTTCAACTCTCATCCAACCCATACACTCTCATACAAGAAGGTAAATTCCCATTCTACGGCTGCGCAATCTGCAATATATCTtacatacatttaaaagaaCTAGATCAACATGTAATGTCGCACAAAAACAGAATCACAAGTTGGGATATAAGAGTAAAAGCGTtggataagaaaaaaaagttaaagaaagctaaaaagaaacaaaaacacaaaACGAAAAGTGACAAAGTAGTCGATATCAATAATGACAGTGGAAtaaataatgatgatgatgataaaacTGAAGGTGATAAAGGTTTGGAGAAGATTTTCAAATGTGCTGGATGCTATAAGCAGTTCTCGCtgtcatattatttaaaattgcatGTAAGGTCTCATACAGGTGAAAAACCGTATCAATGCTCCGAGTGTGGCCTGGCCTTCATTACGGCCAGTAAATTGGGCAGGCACCGAAGGATGCATACGATGGCCAAGGTTATATGTAGGATATGCTTTAAGGAATTTAGCAGATTTGAAACCTTAACTAGGCATTTTGATAAAAAGCATTTAAGTGAGAAATTGGAAGGGGAGCCCTATGATTACAACATAATCCTGCCATACATGACAGAGATGACCGAGGAAGCAGAGAATAAGAAAGACACCACCGAAGTAGCCGAAGAGAAGGCACCGATTGAGCAAGAGGAATTGGAGTCGGAACTTCCAGTGATGATCAAGGTTGAGGAGTTGGATGATACCATCAAGACTGAGGATTCTGATGATACGGACCCGGACTATGAGGATGATGGTGATGATGAAGATTACCAGAACACCAGTTTTGAACAGGAGACGTATAAGATAGAGTTTAATGGAGATGAtaattccGACAATTCCGACTACTTCCCGTCGGACACGTGGACGACGCCAGCGCTGGATCTGCCGGCCGACCATGACAAACCCGTCTGTAAGGAACCCGTCCACGTGCCGCGAAAGAAACGCATCAAGAAGGAAGAACAAGAACCAGACAATGCAGACTCGGAAGACGGCGTGTGCACGTGCAAGGTGTGTCACAAGAGGATCAAGACGGCCGGTTACATGCATATACACATGCGTACTCACACTGGCGAGCGGCCGTTCAAGTGTTACGTGTGCAATAAGGCGTTCATCACCTCGAGCAAGATGCACCGGCATGTGCTGACGCACTCCGAGAGTGAACGGCTAAATGCTACGGCGGAGCATATGGAAGTGAAGGTGGAGCCTGATTGGTTGGAGGATGAGTCGTCTCGAAACGGCCTACCCAAGAAGAGACCGAGAAGGTACAAGCGCGACCCGAGCCTGCCCACCAAACGGAAGCACGAGTGCGACTTTTGCCACAAGCGTTTCGTGCACCTGCAAACGTTGGAAACCCACCGGAGCAGCCACAAGGGCGAAGTGAAAAAAATGACGTGTCACTTCTGCGTCACGGAATTTGACACTTCTGAAGACCTCAACCTCCATCTGTTGACCCATACTGGACCAACACCGTTCTTATGCACGCTTTGCGGGAAAACCTACAAGCGGAAGGAGACAATGGTGTATCATAGACGGACTCATCTGATGGAGAAAAAGTACCAATGCGATGTCTGTTCCAAGTCTTTCACGGCGCCTTGCAAACTTCAAAGGCACTTGGTCAGCCATCGGCCGGATAAGTTTGTGATCCGGTACGAGTGCCCGGTGTGCGCCCATATATTCAACACCAAGTATCATATCGAGATGCATCTGACGACTCACGAGAAGGATGGACAAATACTaagagagaatcgcggcgacgTTATCGCTATGGTGTTGCAGAACGCGAGAAAAATACCCCTACAGTCGGACCCCTCGATGACTACCAACCTTATCACAACCGATGAACGGTCGCGCGTTTGCAACATCTGCGGGGAAGTTTTCCATCACTTTTACTTCCTCGAAGAGCATTTGAAGACCCACGGCACAAAGCTAAACCTGGAATCTGAGGAAGGGCCCAAGCTGGACTCCGAGGACCGTAGATACAAGTGCGAGGTTTGCCAGAAAGGCTtcaaattacattattatttaaaactacacaTGTTTACTCACACGAAAGAAAAGCCTTTTATATGTCAGCGATGCGACAAAGGCTTCATCACTAAAGGCAAGCTCAAAAGGCATCTAGAATCGCACGccggtttaaaaaaataccaatgTCATATTTGTTATAAATTTTTCACGAGGCCCAGTTACTTGAGGATACATGTGAAAACGATTCATGAGAAAGTAAAAGATAGCTATTGTATAGAGTCGTTTGGGTCAGGTTTgcccaattttaatgaaaaggTGAAAGATATGGAGTCATTTAGGTCGAATGTGCCCAATTTTCATGATAAGGTTAATGATAATATGGAGTCATTTAGGCCAAATGCCCCCAGTATTCATGAGAAAGCTAAAAATAGCCATATTGTGGAGTCATACAGAATACTAAGAGAAAATCGAGGTGACATTATCGCCATGGTGTTGCAGAACGCGAGAAAAATACCCCTACAGATGGACCCCTCGATGACTACCAACCTTATCACAACCGATGAACGGTCGCGCGTTTGCAACATCTGCGGGGAAGTTTTCCATCACTTCTACTCCCTCGAAGAGCATTTAAAGACGCACGGCACAAAACTGAACCTGGAATCTGAGGAAGGGCCTAAGCTGGACTCCGAGGACCGTAGATACAAGTGCGAGGTTTGCCAGAAAGGCTtcaaattacattattatttaaaactacacaTGTTTACTCACACGAAAGAAAAGCCTTTCATATGCCAGCGATGCGGCAAAGGCTTTATCACAAAAGGCAAGCTCAAAAGGCATCTAGAATCGCACACCGGTTTGAAAAAATATCAATGTCACATTTGTTGTAAATTTTTCACGAGGCCCAGTTACTTGAGGATACATGTGAAAACGATTCATGAGAAAGTTAAGGATAGCTATAGTCTAGAGTCGTTTGGGGCAGGTGCACCGAGTTTGCATGATAGGATTAATAAAGATAGTCATATTATGGAGTCATTTAGGTCAACTATGCGCAGTTTTCACCTGGAAACATTGCCAGGCACAGATAAAGAGTAG
Protein Sequence
MEQPLETNKPENEVKDLKIIEPEASSEEPKPKVFEISENCILTPEAIVSTKTILNNIVQLSSNPYTLIQEGKFPFYGCAICNISYIHLKELDQHVMSHKNRITSWDIRVKALDKKKKLKKAKKKQKHKTKSDKVVDINNDSGINNDDDDKTEGDKGLEKIFKCAGCYKQFSLSYYLKLHVRSHTGEKPYQCSECGLAFITASKLGRHRRMHTMAKVICRICFKEFSRFETLTRHFDKKHLSEKLEGEPYDYNIILPYMTEMTEEAENKKDTTEVAEEKAPIEQEELESELPVMIKVEELDDTIKTEDSDDTDPDYEDDGDDEDYQNTSFEQETYKIEFNGDDNSDNSDYFPSDTWTTPALDLPADHDKPVCKEPVHVPRKKRIKKEEQEPDNADSEDGVCTCKVCHKRIKTAGYMHIHMRTHTGERPFKCYVCNKAFITSSKMHRHVLTHSESERLNATAEHMEVKVEPDWLEDESSRNGLPKKRPRRYKRDPSLPTKRKHECDFCHKRFVHLQTLETHRSSHKGEVKKMTCHFCVTEFDTSEDLNLHLLTHTGPTPFLCTLCGKTYKRKETMVYHRRTHLMEKKYQCDVCSKSFTAPCKLQRHLVSHRPDKFVIRYECPVCAHIFNTKYHIEMHLTTHEKDGQILRENRGDVIAMVLQNARKIPLQSDPSMTTNLITTDERSRVCNICGEVFHHFYFLEEHLKTHGTKLNLESEEGPKLDSEDRRYKCEVCQKGFKLHYYLKLHMFTHTKEKPFICQRCDKGFITKGKLKRHLESHAGLKKYQCHICYKFFTRPSYLRIHVKTIHEKVKDSYCIESFGSGLPNFNEKVKDMESFRSNVPNFHDKVNDNMESFRPNAPSIHEKAKNSHIVESYRILRENRGDIIAMVLQNARKIPLQMDPSMTTNLITTDERSRVCNICGEVFHHFYSLEEHLKTHGTKLNLESEEGPKLDSEDRRYKCEVCQKGFKLHYYLKLHMFTHTKEKPFICQRCGKGFITKGKLKRHLESHTGLKKYQCHICCKFFTRPSYLRIHVKTIHEKVKDSYSLESFGAGAPSLHDRINKDSHIMESFRSTMRSFHLETLPGTDKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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