Ning007687.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nebria ingens
Gene Symbol
THAP6
Assembly
GCA_018344505.1
Location
JADQWA010000091.1:159442-164554[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.13 10 6.8 1.3 1 20 311 330 311 334 0.87
2 12 0.017 1.3 9.6 0.5 3 23 444 464 442 464 0.94
3 12 3.3e-05 0.0027 18.1 4.9 2 23 468 490 467 490 0.95
4 12 0.00019 0.016 15.7 2.7 3 23 551 571 549 571 0.97
5 12 4.7e-06 0.00038 20.7 2.6 1 23 577 599 577 599 0.96
6 12 0.00011 0.009 16.4 4.5 1 23 605 627 605 627 0.95
7 12 0.0031 0.25 11.9 0.2 1 23 633 655 633 655 0.98
8 12 3.5 2.8e+02 2.3 1.6 2 23 668 690 667 690 0.92
9 12 0.00079 0.064 13.7 0.9 1 23 696 718 696 718 0.98
10 12 7.5e-05 0.0061 17.0 3.4 1 23 724 746 724 746 0.98
11 12 1.1e-05 0.00091 19.6 2.4 1 23 751 773 751 773 0.98
12 12 5.7e-05 0.0046 17.3 0.2 1 23 779 801 779 801 0.97

Sequence Information

Coding Sequence
ATGACTATGTGCGTGGTTCCTTACTGCGGCAATCGCTCAATTAGAAAAAGTGCTAAACAAATACAATTTGAGAAAATAAAGCCGCATCCCACCACATACCACAAGTTTCCTAATAATGAGAACATGTGCAAAAAATGGATTTTAGCCATAAATCGCCCGAATTGGTTTCCAAGACCGTCGTCCAAAGTTTGTTCAGATCATTTTAAAGAGGAATTTTTCGACCGGTCTTCACCATTTCGTGTCATTTTAGCATCTAATGCAGTTCCATATTCCCGTTGTTCTGCAAATGTACAAGAAGTTGAAGAAAAATCACATTCAGATTCCGTATCTGAAAAAGAAGATACGCTATCTGATGCGTTAGCCATTACCGAATCAGATCAAAATATAAAAATGGGTGGTAATAAATTCGTTAATATGTTGGCTAAAGAAGAAGGACCAATAAACGATACTATAACTGCTAACATAATTACAACTGAAAATACTGTCGTCCCACAAACAAATACAGTTCAACAAACTTATTGTAGAATTTGTTCAAAACTTGCACCTATTTCTTCACTTACATCACTCTACAACAGTCCAAAAAGTTTAGTTTACTTAGAACTGTTAGATTTACTACTGCCTGGATTGATTAAAGTCGATATTAGATTGCCGACGTGTATTTGTAGAATATGTGCAGTTGTGTTGGATCATATAGGTGAAAATATAAAAACATTCAAAAAAGCAGATGATGAACTTAAGAACATGTTTAAAGTTAAATACGAAGATGAAGTACAAGAAGAAAAAGATGAACCAGTATATCTTATTGTAGAAAATACTCCTAAAGAACCAGGCGCAACCATCGAATTAATTCCAACTGAAAAAGCAGTAACTGAACCAGTACCATTTTTACTAGATGAAATCACCGAAATAAACGACATCGAAATGATAAATTTCGAATGTATACACTGCAATAAGCTATTCCCATCCAAAAATGATTTACTCCAGCATTCATTTCTCATCCATTCTGTGTCAAAATTCGATAGAATATCTTGCAGAATGGTTCAAACAAAGCTCGCTGACGAAGATACGGTAGAACTGCCTGCAACTAAAGTCGCAATCATTGAAGAAACTCAAAAGGAACCTGATGATCCAGCTGAGAAAACAAGTGATGAAGAAGACGAACCAGAAGACAGTGAAAGCACTCAAACTTATTGTATTATTTGTTGTGCGCTTTTTGATTCGCGAACCGCGTTAATGAGTCACACTGTGACGTATCACCAAATCATCGCTAAAGATTCGATTTTAAATCGCTCTATAACGAAAAATTTGTTAAGTAAAGGTGTTATTAACTGTACTAGATGTCCAGAGTCGTTTTCTTCTTTGAAAGTTTATCGACAACATGTGCTGCAACATCTTATTGTGAAGTGTGATCAGTGCGGTAAAAGCTTTACTAGTGCGCATAAATTAAATAAACATCATAGTAGTACGCATGTTATACCGCATTCAACAGATGAGGATGATGTTGATAATGTAGATGAATTAAATAAAAATGCTGATAATGTAGAAGAAAGTAGTGACCTAGAGAGCGCATCGAAAAGAAAAAAGAATACAGTTGATGCAGAAGTTACGAAAACATCTAAGAATACTGTTATGACGGCAAAATCTTGTCTTTGCAGTACATGCGGTAAACTTTTTCCCTCATCAGCGCATCTTGCTCAACATCGTCGAGTTCATATCTCTGCTCGCAATTATCTCTGCCCCAAATGTCCAAAGGCATTCAAAACATACACGCATCTTGCGAAACATCAATACACACACAGCACCGAACCGAATTTCTGTTGTCAGATATGCGGTAAAACATTTCGCTCGCCGGGCGGCCTACACAAACACTCCTACCGCCACAAAGATAAAAAACCATATTATTGCGAGTTATGTGGACGCGGCTTCTTATTTCCTGCACAGCTTGCGTTGCATCGAAAACGCCACGAAAAAATACGAAAAGTGGACACAAAATACGGAAATAAATGTCGCATCTGTAATATTGAGCTTCATAGTTTTAACGAGTTAAAATCCCATTTTACCGTAGAGCATTCGGGTTTGAAACCTTATGAGTGTAACGAATGTAAGATTTCGTTTTGGACGAAATCTCAATTCGACGTCCACAAACGGGTGCATTCGGGTGAGAAGCCGTATAAGTGTGATAAATGCACGGCTTGTTTTCGTAGTAGTTCGGGCTTACAACAGCATAAATCTGTCCACAGTGATGGAGATTTTGTTTGTTCGATTTGCGTTAAAAGATTTAAACGGCGGGAACATTTGGTACTACACGAAAGAACTCATTCTGGAGTTAAAATGTTTCCGTGTCCGGGTTGCGATAAAGTTTACTCGCAACGTCAAACAATGGTTAAGCACAGTCAAATACATGATCCTAATTTTGTTGAAAGAGCTGATAAAATAACGAATTCGTTTAAGACACAAGCGAAATTATTGCTACAAATACAAGATGATGAAATGGGGGCAGTTAATACGTTAGAAGAAGTGGTTGAATTTGAACAAGTAACCGAATTTGAACAAATAATTGAATTGAAACCATTAGCCAAAATAGAAGTGCAACAAATAGAATCATCACAAGCAGATTATATAAGACAATCAATATTAAGAATGGATCATGGGGTAACCATTAATGGAACTCCGATTATGGAGTTAGTTCGATACAATTGA
Protein Sequence
MTMCVVPYCGNRSIRKSAKQIQFEKIKPHPTTYHKFPNNENMCKKWILAINRPNWFPRPSSKVCSDHFKEEFFDRSSPFRVILASNAVPYSRCSANVQEVEEKSHSDSVSEKEDTLSDALAITESDQNIKMGGNKFVNMLAKEEGPINDTITANIITTENTVVPQTNTVQQTYCRICSKLAPISSLTSLYNSPKSLVYLELLDLLLPGLIKVDIRLPTCICRICAVVLDHIGENIKTFKKADDELKNMFKVKYEDEVQEEKDEPVYLIVENTPKEPGATIELIPTEKAVTEPVPFLLDEITEINDIEMINFECIHCNKLFPSKNDLLQHSFLIHSVSKFDRISCRMVQTKLADEDTVELPATKVAIIEETQKEPDDPAEKTSDEEDEPEDSESTQTYCIICCALFDSRTALMSHTVTYHQIIAKDSILNRSITKNLLSKGVINCTRCPESFSSLKVYRQHVLQHLIVKCDQCGKSFTSAHKLNKHHSSTHVIPHSTDEDDVDNVDELNKNADNVEESSDLESASKRKKNTVDAEVTKTSKNTVMTAKSCLCSTCGKLFPSSAHLAQHRRVHISARNYLCPKCPKAFKTYTHLAKHQYTHSTEPNFCCQICGKTFRSPGGLHKHSYRHKDKKPYYCELCGRGFLFPAQLALHRKRHEKIRKVDTKYGNKCRICNIELHSFNELKSHFTVEHSGLKPYECNECKISFWTKSQFDVHKRVHSGEKPYKCDKCTACFRSSSGLQQHKSVHSDGDFVCSICVKRFKRREHLVLHERTHSGVKMFPCPGCDKVYSQRQTMVKHSQIHDPNFVERADKITNSFKTQAKLLLQIQDDEMGAVNTLEEVVEFEQVTEFEQIIELKPLAKIEVQQIESSQADYIRQSILRMDHGVTINGTPIMELVRYN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01040181;
90% Identity
iTF_01040181;
80% Identity
iTF_01040181;