Ning005834.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nebria ingens
Gene Symbol
PRDM15
Assembly
GCA_018344505.1
Location
JADQWA010000297.1:39816-44466[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.055 4.4 7.9 2.9 2 23 213 234 212 234 0.96
2 17 0.00015 0.012 16.0 0.3 1 21 243 263 243 264 0.96
3 17 0.0005 0.041 14.4 4.0 1 23 271 293 271 293 0.99
4 17 0.00029 0.023 15.1 0.2 3 23 299 319 297 319 0.96
5 17 0.00057 0.046 14.2 5.3 1 23 325 347 325 347 0.99
6 17 4e-06 0.00033 21.0 0.5 1 23 359 381 359 381 0.97
7 17 8.4e-06 0.00068 20.0 2.4 1 23 387 410 387 410 0.96
8 17 0.029 2.3 8.8 0.7 2 23 523 544 522 544 0.97
9 17 0.0016 0.13 12.8 0.1 1 20 553 572 553 574 0.95
10 17 0.11 8.6 7.0 4.6 1 23 580 602 580 602 0.99
11 17 0.00017 0.014 15.8 0.1 3 23 608 628 606 628 0.96
12 17 0.052 4.2 8.0 4.3 1 23 634 656 634 656 0.99
13 17 2.8e-05 0.0022 18.3 0.1 1 23 668 690 668 690 0.96
14 17 0.014 1.1 9.8 4.6 1 23 696 719 696 719 0.94
15 17 7.8e-05 0.0063 16.9 1.6 3 23 726 746 724 746 0.97
16 17 0.024 2 9.1 2.0 1 14 752 765 752 765 0.94
17 17 6.9e-05 0.0056 17.1 1.4 2 23 781 803 780 803 0.96

Sequence Information

Coding Sequence
ATGGAATTTTGTCGCCTTTGTTTAACTGCTACAAATTTAAAAATTAATTTAAAATCTTTAGATAATCATACAATATTATTTAAGGATAAATTAAAAATGATTTGCGAAATAAAAATAAATGAAATTTTCCCTACAGCAATTTGTAATTTATGTGAATTCAAAGTACAACAATTTTTTCAATTTAAACAAATGTGTTTACAATCGAATTTGTTGCTTAATAAACATAAGGATGAATTAAATAAATTGTTTATACATAAATTACGTAGGAAAATATTGTCTGATTATAGTATTGATTCGAAACAAAAGAATATTGATGAGACAAATAATAGAATAAATGAAACAAATGATGGTTTCGGTTTCAATAGCGATGAATTTCTTCAACAAAATGAATTAGAAGAAATTTCAACTATAGAAGATAAGAATACCAAAATACGAATTGATACTAAATCATCCCAACTATATAGTCATACCGATACAACAAATATAGAAAATACTAAAATTAGTCCAAAATTATTAAAAAACAAATTTAAAACTGTTAAAAAATTGAAACGTGTTAAAATTAAATTAGTTGACCAAAATAAATCAACTGGCGACAAAAACGCGTCTAGTAAACTAAAATCAGAATCGACCTCCATACATTGTCACATTTGCGATTTAATGTTGGAAAACTCCAAAGAATTCGGTCACCATATCAATATACACATACACCCGAATGCCGACGGAAATTTTCAATGTGGAAAATGCGAGAAAATATTCGGTAGCAAACTCTCGTTACGTAGACACATAAAGGCCTTTGTCAAAGACTGTCCGTACAAATGTGATCAGTGTGATAAGATTTATCATTTTCGAGCTTCGTATATCAATCATATGAAGAAACATGAACCGAATCAAATTTGCGCTAAATGTGGACTGAGTTTTCCGACTGTTACATTGCTGAAACGACACGAGCTCACACATTCGCCTGACAAACCTTATAAATGCCAAATTTGTTCTCAGGAATTGAAACATAAGAGTACTTATAACACTCACATGAAACGCCATGAAATGACACCAGAGGAGCGCAACGCGCGCAAATTTTCGTGTGAACTATGCGGGAAAACCTATCGAAGTTTAGACAACTTAAACATTCACAAAATCTCGCATACAACTGAGAAAACACACGAATGCACATTGTGTGGCAAAAGGTTTAAATACAACCGAAGTCTAAAGAACCATGTGCAGATTATACATTTTGGAGCGAATAGTAATGAAAACAACGCTGATGAAGTGTTTGCAACTGATTCGGTAATTGAATTTGGAGAAGAAATTTCAATAATAGAAGATGAAAATATCGAAACTATAAATAATGTTGAATCACTTCAATTATATAAGTCCTTAAATACAAAAATAGAAAACACCAACTCAGAAATTATTGTAACATTGCCACATGAACGTAAAACAATCAACAATATTAAAGTGATTAAAATTGAAATAGTTCGTAGTGCTGATCAAACTGTATTAAATAGTACTGACCACAAAAGCACCTCTACTATTACCAAAAACATAAGCGATATAACAAATACCAAACGTTGTCACGTTTGCGACCTTATTTTGGATAACACCGAAGAATTCAATAACCATATCACCATTCACATACTCCCGAATGCCGAAGGCGAACACCAATGTGGAAAATGCCAGAAAATATTTGGAAATCCAGTCTTGCTTCTGAATCATATAACTGAATTTGTAAAAGATCCGTACAAATGTTGTAAATGTGATAAGTTGTATCAGTTTCGGCTTCAGTATATCGAGCACATGAAGATACATGATCCAAATCAAATTTGCGATAAATGTGGGTTGAGTTTTCCGACTGTAGAACTACTGAAAAAACATGAAGCCACACATTCAGTGGACAAACCTTATAAATGCCAAATTTGTTTTCAGGAAATGAAACATAAAGGCACTTACGTCACTCACATGAAACGCCATCAAATGACACCAGAAGAGCGTAATGTGCGCAAATTTGCGTGCGAAGTATGCGGGAAAATGTACCGCACTTTAGACGCGTTAAACATCCACAAAATATCGCACACAACTGAGAAGAAACACGAATGTGCGTTGTGCGGCAAAAAATTCAAATACACTCGTTGTTTACGGTATCATGTTGAGATTAAACATTTTAATAAACGATCTATTTGCCATGTGTGCGGTAAAAAATTCGTTACTGATACTGTTTTAAAGAAACACTTGCGTTTGCACACCGGTAAACGACCGTACAAGTGCCATTTGTGTCCGAAAGCGTTTTGTGACCCGTCAATTCATTACAAGGATATGTTAACGCATTCTAATATGCGGACGCAGGTGTGCCAGTATTGTGGAATACAGTTTAAGCAGAAGAATTCTTTATACATGCATATCAAGAAGAAGCATTCAGATGTGAGTGACATTAACGCTGAAGATGATATTATTGACTGTTTAGATATTTAA
Protein Sequence
MEFCRLCLTATNLKINLKSLDNHTILFKDKLKMICEIKINEIFPTAICNLCEFKVQQFFQFKQMCLQSNLLLNKHKDELNKLFIHKLRRKILSDYSIDSKQKNIDETNNRINETNDGFGFNSDEFLQQNELEEISTIEDKNTKIRIDTKSSQLYSHTDTTNIENTKISPKLLKNKFKTVKKLKRVKIKLVDQNKSTGDKNASSKLKSESTSIHCHICDLMLENSKEFGHHINIHIHPNADGNFQCGKCEKIFGSKLSLRRHIKAFVKDCPYKCDQCDKIYHFRASYINHMKKHEPNQICAKCGLSFPTVTLLKRHELTHSPDKPYKCQICSQELKHKSTYNTHMKRHEMTPEERNARKFSCELCGKTYRSLDNLNIHKISHTTEKTHECTLCGKRFKYNRSLKNHVQIIHFGANSNENNADEVFATDSVIEFGEEISIIEDENIETINNVESLQLYKSLNTKIENTNSEIIVTLPHERKTINNIKVIKIEIVRSADQTVLNSTDHKSTSTITKNISDITNTKRCHVCDLILDNTEEFNNHITIHILPNAEGEHQCGKCQKIFGNPVLLLNHITEFVKDPYKCCKCDKLYQFRLQYIEHMKIHDPNQICDKCGLSFPTVELLKKHEATHSVDKPYKCQICFQEMKHKGTYVTHMKRHQMTPEERNVRKFACEVCGKMYRTLDALNIHKISHTTEKKHECALCGKKFKYTRCLRYHVEIKHFNKRSICHVCGKKFVTDTVLKKHLRLHTGKRPYKCHLCPKAFCDPSIHYKDMLTHSNMRTQVCQYCGIQFKQKNSLYMHIKKKHSDVSDINAEDDIIDCLDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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