Nbre001459.1
Basic Information
- Insect
- Nebria brevicollis
- Gene Symbol
- -
- Assembly
- GCA_944739395.1
- Location
- CALYJC010000014.1:1604717-1610856[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 5.4e-05 0.005 18.1 1.2 2 23 881 902 880 902 0.97 2 10 2 1.9e+02 3.7 0.4 1 23 907 929 907 929 0.95 3 10 0.018 1.7 10.2 1.0 3 23 933 954 932 954 0.94 4 10 0.00052 0.049 15.0 0.5 1 20 959 978 959 981 0.93 5 10 0.0014 0.13 13.7 0.8 1 23 987 1009 987 1009 0.98 6 10 6.8e-06 0.00064 20.9 1.3 1 23 1285 1307 1285 1307 0.98 7 10 0.0046 0.43 12.0 1.4 1 23 1313 1336 1313 1336 0.97 8 10 7.5e-06 0.0007 20.8 0.7 1 23 1344 1366 1344 1366 0.95 9 10 0.48 44 5.7 7.6 2 23 1373 1394 1373 1394 0.97 10 10 5.1 4.7e+02 2.5 1.1 1 12 1399 1410 1399 1413 0.86
Sequence Information
- Coding Sequence
- ATGGAGGTACGAGAAGACCTACTATTGAAGTTAAAATGCTCAATTTGTAAAGACTATTTATCGTGTGCgccaatattaattaaaacaaatgggAAAAGTGTTTGCGGCCGATGTCCGACGGATGACGAAAATATAACCAGAAATATCCCTTACGAAGAGTTGGCTAGCATGACTCTATTCCCGTGCATAAATAAAAGTGTGGGTTGCGATAAAAAAGTACCGTTCAATAAAGTAGcaaatcatgaaaaatattgCCGCTTCACCAAGTTCAACTGTCCGATCGAACCGGTTAACTTTTGTGAGTGGAGCGGCAAACGTGTCTCATTCTACCAACACTGCAAAAACAAACATCCGGATCACATTTACGAGAATTCGAAACAATTCGCGCACAACATTAAAACCAACAACGAACGCAATCTGGTGTTAATGTTTAATAGTTTAGTGTTTTTAGTGCAGTATAAAGTAAGTGTGATCCATGCAAAAATCTGGCATTGTGTCCGATATATTGGCAACTCAAACTTAACATCACAATTTAATTTCGAAGTGCACATAAAATGCGACGAGAAATCAATGAAATGCTCAAAACAAGTCGCGGCGCAAAACCGTATGATAATAGAACAAAAATGTTCGATTGAAACATGCATAAATAGTCTATTAACACTTTTCGGCACTTTTAAAAACGTCTACTTCTCAATCATCATCAAACAACAACTCGACATGCAACTGTTAGCGACAGTCACTTGTATCCGTTGCCACAAATACGCGAAAGAAGAGATCTACATTTGCGAAACAGAAAATGGTTGCGTTTGCTACGATTGCAATCGAGACAAAGAAGTCAAAAACGAATTCTTAATGGACATTAGCACCCAACTATTCTATCCATGTAGCTTTCAAATAAATGGTTGCACATATATAGACGTAATGACAAATATAATACGACACGAAAACTTTTTTTGTAACTATTCAAAATGTCTAATTTGCAACCAACCAGTTTCAGGTAATAAGAAGAACCACTATGATAAACACCACGCGAAATTAATATGGCAAACGATGAAAATATCGCATAAGAAAATCGCGATAAAAGAATTCCAATATTCGATCATTCAGAATGaggatttgttttttatttgtggttGCGGCAAACAGGATGATACGTTCATATTTTTTGCTAGCTCGGAATTACCGATTGAAGTGTTGGAATTGTATAAATGTCGCTTAATTATAAGAGAATTGAAATCACTATATGATCAACGACCCAACGAACTAACTTTGGCGGAAATGCTAATGTCCTGCACATCAATTCAGtattaTGGAAACGATGGTCTGCCGCCAAATATGTGTCTGGATTGTGTGAGTGAAATAAGACGATCCTacaaattttcattaaaatgccaAGACTCAGATGACCGGTTGCAGACATATTTACAAACACTCCACAAAGCAAAgcaaatagatatttttaaatatgcgACAAAAGCATCGGAAATTTTATCTAATAATTCTATTAATTCCAATCCACATTCTCCTCAAATGAGCATCAAATATGAATCTGATATTGAAGATCCGTTACAAGATTCTTTATCAGTTGATGAATTAGATAATGAGATGGATACACAAGTGGacgtatatgaaaataaaattgataaaaattaccCTAAGCCAGCCATTAGTAGTGAACAGGATCTTGAAATGACTTTAAcggaaaatattaacaaaaatcTAAAGGCGCTATTCGaatataataatgaaacatCCACCAAATCTTTGAATCCAAAGTTAGACTCGATAAAAACTGAAATTCATTATGAAGAAGACTATTCGTTACCGATACCAACAATTAGTGGTATAAGAAATGAAAACAATCTATCAAACGACCCAGTAAATTCATCAGCAGATGTAGAATTGAATCAAATAAATGGATCTACAATATTAGTTCCCACAACAAACATACATTTAGAAAAAAGCAACATACAATTACCTCCACAAATCCAAAATAGTATCAAGACTAAATCGAAAAATTATTGTATAcctataaacaatttaattcctGTTGTATGTTTGAAGCGgctaaatttaaaagttttaacaaaCAATCAAGTATcactaaataaaatagcaaCACAACTGGTTAACACTAAAAAGAGTTTAGAATTTCAAGAAACGGACGACGAAGACTCTGAATCTTTTTATTCTGGTTCAGATTGTGAACAATCTGATGGTGATGAGTCAATAAATGTAGATTTCCGAACTAAAAATCAGAGTCAAAATGCGCATACGGACGAGAAAATCCAACAAACTGAGATATTAAATACTTCGAATGAAGCTAAATTGCCTTATAAACAAACGACAGAACAAAGTAGTATGGAAGTAGCAAATAGTGTCGCTGAATCGATGACTGTCGTGAATGATATTTCCGAATCGCTTGATGCTGCAACAACGAGCAAGCATTACGAATTAAGAAAACGGACATGCACTAAACGGTATACTGGATTCACTGATGAAGACTTCTCAAGTGACCCAAATTATACTGATAGTGAATCATCGAGTAATGAAGATTCTGATAATGATGAACCACACCAAAAATCAGTTTCTGTTGCCCGTTCCAAGATTTCAAAACCGGTTGAATTCAAAAAACATCTAAAATGTTCAAAATGCGATCGAACATTTTACACTGCGAATGACTATGAAGAGCACCTCAAAACCCATTCTACAATACCGTATACCTGTCCAAATTGCGCCGAACCATGCGAGACAATAATTGTCTTAAGGAACCACAAGTACATGCATTTTCCTTCATGTGCACATTGCCGGATTATTTTTGTGTCTAACAATGACTTGAAAAATCACGTGCAACAATATCATACAGATAAGCTTTATTGTTGCACTTTATGCGAAAAGATCTTCGCAACAGAAAGTAGTTTAGCTAATCATATGCCAGTACATGTAAATGTAATGCAGTATACTTGTACTGTTTGCGGGGAAAAATATCAAGAGAACAAATCATATGAAGAGCATATGCTTAAACACTCGAATGGAgctgaattaaataataaaaccaatCAAATAAATCCAACTATTGCACCCAGCAATATACATCACAATAAGCAATGTGAATCACAAACGAAACCATCAAGTACTAACGAAGaattatcaaaaaataaaCCACCAATTAGTGATCCAATCAAACTAGCACATTTTATCAATGATAAAATGAAACTACTCATTCATAAAGATCGCGTAGATCAATCAAATACGTTAAACCATCAAACTCAAACTGAGCCCCCTATTACAAATTTAAGTGAACCATTACAAATAAACCAGCTCAACGAACTGGAAAACAATCCTCAAAGTGAAAATTTGATTGATATAACCCAACAACAGGAAGAAAACAGTCATTTGAATGTTGATAAATCATCAAATGTCATGGAAAGTGAATTGTGCCAGAATCCAATTGAGCAAATAGTTGAAAAATTAGACGTAATAAATTCAGTACCATCGATTATCGAAATTGATcaatcaattattaataatgatCAAAATGGAATGTTAAGCAATGATGCTATTATTATAGATGATTCTATAGTTGAAAACAATCAAACTAGTAATGAATCATCAAATATTGTGGTCAGTGATTTAAGTAAGAATCAAAATGAACAAACAATTGAAAAATGCAACATAATAAATGCCGTACCATCAACAATTAgttttgttgaattaattattactcAAAAACCAAGCAATAATGTgatcattataaataatgctGTGGTTGCAAACAATCAATTTATAAGATTAACACCTAACGCAATTTTTTGTCCGCAACCGTTAGGTGGAGTACCTATACCAAAACTATTTTCATGCCCGAAATGTGACCGTAAATttgatcaaataaaaaatgttaccAAACATATGCGTGTGCATCCTGAAGTTAAACAATATAAGTGTGAAAAGTGTGATGCTTTATTCGGGACAGCTATTTATTTACAGAGGCATCATTTGCGTACACATCCCACTAACGTAAAACGGATGTATGCTTGTCCAGTTTGCAAGAAAAAGTATACAACCCAATCATACTTGAAGGATCATATGGGCTTACACGAGAAAGAACCGAAAAATTCTTGTAAATTTTGTCCACGGAAATTTCACTTGAAGAAATCGATGCATATTCACATGCGTAAACATAATGATGTACGTTTCATTTGTACCGTTTGCGGAAGAATGTGCGACAGAGAGAGAAAAGAACTTTCTGAATAa
- Protein Sequence
- MEVREDLLLKLKCSICKDYLSCAPILIKTNGKSVCGRCPTDDENITRNIPYEELASMTLFPCINKSVGCDKKVPFNKVANHEKYCRFTKFNCPIEPVNFCEWSGKRVSFYQHCKNKHPDHIYENSKQFAHNIKTNNERNLVLMFNSLVFLVQYKVSVIHAKIWHCVRYIGNSNLTSQFNFEVHIKCDEKSMKCSKQVAAQNRMIIEQKCSIETCINSLLTLFGTFKNVYFSIIIKQQLDMQLLATVTCIRCHKYAKEEIYICETENGCVCYDCNRDKEVKNEFLMDISTQLFYPCSFQINGCTYIDVMTNIIRHENFFCNYSKCLICNQPVSGNKKNHYDKHHAKLIWQTMKISHKKIAIKEFQYSIIQNEDLFFICGCGKQDDTFIFFASSELPIEVLELYKCRLIIRELKSLYDQRPNELTLAEMLMSCTSIQYYGNDGLPPNMCLDCVSEIRRSYKFSLKCQDSDDRLQTYLQTLHKAKQIDIFKYATKASEILSNNSINSNPHSPQMSIKYESDIEDPLQDSLSVDELDNEMDTQVDVYENKIDKNYPKPAISSEQDLEMTLTENINKNLKALFEYNNETSTKSLNPKLDSIKTEIHYEEDYSLPIPTISGIRNENNLSNDPVNSSADVELNQINGSTILVPTTNIHLEKSNIQLPPQIQNSIKTKSKNYCIPINNLIPVVCLKRLNLKVLTNNQVSLNKIATQLVNTKKSLEFQETDDEDSESFYSGSDCEQSDGDESINVDFRTKNQSQNAHTDEKIQQTEILNTSNEAKLPYKQTTEQSSMEVANSVAESMTVVNDISESLDAATTSKHYELRKRTCTKRYTGFTDEDFSSDPNYTDSESSSNEDSDNDEPHQKSVSVARSKISKPVEFKKHLKCSKCDRTFYTANDYEEHLKTHSTIPYTCPNCAEPCETIIVLRNHKYMHFPSCAHCRIIFVSNNDLKNHVQQYHTDKLYCCTLCEKIFATESSLANHMPVHVNVMQYTCTVCGEKYQENKSYEEHMLKHSNGAELNNKTNQINPTIAPSNIHHNKQCESQTKPSSTNEELSKNKPPISDPIKLAHFINDKMKLLIHKDRVDQSNTLNHQTQTEPPITNLSEPLQINQLNELENNPQSENLIDITQQQEENSHLNVDKSSNVMESELCQNPIEQIVEKLDVINSVPSIIEIDQSIINNDQNGMLSNDAIIIDDSIVENNQTSNESSNIVVSDLSKNQNEQTIEKCNIINAVPSTISFVELIITQKPSNNVIIINNAVVANNQFIRLTPNAIFCPQPLGGVPIPKLFSCPKCDRKFDQIKNVTKHMRVHPEVKQYKCEKCDALFGTAIYLQRHHLRTHPTNVKRMYACPVCKKKYTTQSYLKDHMGLHEKEPKNSCKFCPRKFHLKKSMHIHMRKHNDVRFICTVCGRMCDRERKELSE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -