Basic Information

Insect: Nebria brevicollis
Gene Symbol: PLAGL2
Assembly: GCA_944739395.1
Location: CALYJC010000008.1:1800310-1802097[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 7.1e-05 0.0066 17.7 1.5 1 23 195 217 195 217 0.96

2 7 9.8e-06 0.00091 20.4 4.5 1 23 223 245 223 245 0.98

3 7 1.3e-05 0.0012 20.0 5.6 1 23 251 273 251 273 0.98

4 7 0.057 5.3 8.6 0.8 1 23 280 304 280 304 0.94

5 7 0.00016 0.015 16.6 0.2 2 23 312 333 311 333 0.97

6 7 8.5e-05 0.0079 17.5 2.0 1 23 347 369 347 369 0.97

7 7 0.00012 0.011 17.1 2.9 1 23 375 398 375 398 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	7.1e-05	0.0066	17.7	1.5	1	23	195	217	195	217	0.96
2	7	9.8e-06	0.00091	20.4	4.5	1	23	223	245	223	245	0.98
3	7	1.3e-05	0.0012	20.0	5.6	1	23	251	273	251	273	0.98
4	7	0.057	5.3	8.6	0.8	1	23	280	304	280	304	0.94
5	7	0.00016	0.015	16.6	0.2	2	23	312	333	311	333	0.97
6	7	8.5e-05	0.0079	17.5	2.0	1	23	347	369	347	369	0.97
7	7	0.00012	0.011	17.1	2.9	1	23	375	398	375	398	0.95

Sequence Information

Coding Sequence: ATGGGAACACCAGGCGACAAATTTCCAATCGATAAGGTAGCACATGGTGTACCTTTGACTGGAACCGCGTCGTCAACATCATACGATCAAACCGAAGAACCACCGGACGTAGTACAATCGCCAACCATGACGATATTGCAAAGCATTCCGTCGTTAGGCATTTTCGTCGAGCAGAGCCACCGGGAACCGCAGCTTCCAACCCTAAATCCTGGACCATCGTTGAGTCTTCACACGTTAGAAGACCTCGAGAAACAACTACTAATCGACACAACTACATCAGAATCTGATAATTCTTCATCTAATGTGCCTTTACTTGTCGATAATTTTACAAATCCACCATCTGCTCCTAAAGCATTCTTTAAACAAGTTACCAGTCCGCAAAAATCTACCAGTATTGTTCAACAGTTAAGTTTACAAGCATCTACATCAAATAAATCTAGTATCGTTATTGATGAGTTAAGTTTACCGGGACCATCCGGTCTTCAGACACCTAAAACAACAAAACCTAGTTCCACTTTAGTCAAAATCGCACCGAAACGCAATAAAAAACCACCGCTTAGTTCACAGACACCAAAAAAACCACATATCTGCTCCATATGTAACAAAAACTTCCAAACCTCCGCTAAATTAACATCGCATCAAATTGTCCACTCGGGCAGTACACCGTTTAAATGCGAGCACTGCAAAAAAACGTTCAGCTCCAAGTTTAAACTTGTGCGCCATGTGCTCATACATTCCGATCGTAAACCGTTCAGTTGTACGGTCTGTGAACGGACGTTCCATCGTAAAGATCACCTGAAAAATCACATCAAAGTGCATAGTCCCAGCAAAAAAGTGTACGCCTGCGAAAAAACAAACTGCAAAAAAGAGTACACATCGGTGATGAGTTACCGCAAACACTTAGCGCTGCATTCGGCCGAAGAGGGTAGTCTTGAGTGTAAAATCTGTACGAAAGTATTCGAAACAAAAGCGGATATTATGTATCATTTGAAAATTCACGCAGGCAGTCGAACAGTGAAAAATCCaaacgaaaaaaaattcaCTTGTGATTATTGCGATCGCAAATTCTTCACGCGAAAAGATGTACGCCGCCATTTGGTTGTTCATACAGGCTCACGGAATTTCCTCTGTCAATTCTGTCCGCAACGATTCGGTCGAAAGGATCACTTAGTGCGACACATTAAAAAATCACATTCGCGAAATTACACCGAGCTAGATTCGACATCCACGGATGCAACGAGCGTTGCACCGTTATTCGAAGTGTCTGATTTACCAGCAGAGCCCAGTTACAGTGAGGTGAAACAAGAAATATCACAATTAGAAGTCGAGAGTATTTTAGATTATTCAGACGATAAAAACGAGATAAAATTAGAGGAGCTTCCCGGCGTACAAAATCTCTTATTCTCGCGTAGTTTCACCGAACTGAGTCCGATGTTGTGCTCGGAACCGGAACCTTTGCCGTTCATAACGCATGGCGGTTCCGAATCAGATTTACTACCGCAAACGCAATTACCGTCCGATTCGGAGCTGCTGAGCGAGTTGGATGTGATCAAAAGTGAACTGGAACAAGGTATTGTTGCACATGAAGTGGTCGGGGCGAGTGCGGGACTTATTGAAGTTGAAAGCGATTTGGAATTGCAGAGTCAACAACTGTTACCCAGTGATATGATGGATAGTGATTTGTTGCGACTGATTGGCGAAGGTGGCAATCAGTTAACGGATGACGAGAATAATTTGCCACTGCCCGGTTTTAGTCAGGTGTTCAAACAACAAGAACCCCCGTCTTGA
Protein Sequence: MGTPGDKFPIDKVAHGVPLTGTASSTSYDQTEEPPDVVQSPTMTILQSIPSLGIFVEQSHREPQLPTLNPGPSLSLHTLEDLEKQLLIDTTTSESDNSSSNVPLLVDNFTNPPSAPKAFFKQVTSPQKSTSIVQQLSLQASTSNKSSIVIDELSLPGPSGLQTPKTTKPSSTLVKIAPKRNKKPPLSSQTPKKPHICSICNKNFQTSAKLTSHQIVHSGSTPFKCEHCKKTFSSKFKLVRHVLIHSDRKPFSCTVCERTFHRKDHLKNHIKVHSPSKKVYACEKTNCKKEYTSVMSYRKHLALHSAEEGSLECKICTKVFETKADIMYHLKIHAGSRTVKNPNEKKFTCDYCDRKFFTRKDVRRHLVVHTGSRNFLCQFCPQRFGRKDHLVRHIKKSHSRNYTELDSTSTDATSVAPLFEVSDLPAEPSYSEVKQEISQLEVESILDYSDDKNEIKLEELPGVQNLLFSRSFTELSPMLCSEPEPLPFITHGGSESDLLPQTQLPSDSELLSELDVIKSELEQGIVAHEVVGASAGLIEVESDLELQSQQLLPSDMMDSDLLRLIGEGGNQLTDDENNLPLPGFSQVFKQQEPPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01040368; iTF_01041245;
90% Identity: iTF_01040368; iTF_01041245;
80% Identity: -