Basic Information

Insect: Nebria brevicollis
Gene Symbol: Rgn
Assembly: GCA_944739395.1
Location: CALYJC010001853.1:38342-69302[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00017 0.016 16.5 0.9 1 23 278 300 278 300 0.98

2 8 0.011 0.98 10.9 4.4 1 21 306 326 306 330 0.89

3 8 0.12 11 7.6 0.1 2 20 574 592 573 594 0.92

4 8 6.5e-06 0.00061 21.0 2.0 1 23 1269 1291 1269 1291 0.99

5 8 3.5e-06 0.00033 21.9 4.2 1 23 1297 1321 1297 1321 0.92

6 8 1.4e-05 0.0013 20.0 0.9 3 23 1833 1853 1832 1853 0.97

7 8 0.00038 0.036 15.4 2.3 1 23 1859 1883 1859 1883 0.92

8 8 0.0012 0.11 13.9 2.9 1 23 1901 1925 1901 1925 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00017	0.016	16.5	0.9	1	23	278	300	278	300	0.98
2	8	0.011	0.98	10.9	4.4	1	21	306	326	306	330	0.89
3	8	0.12	11	7.6	0.1	2	20	574	592	573	594	0.92
4	8	6.5e-06	0.00061	21.0	2.0	1	23	1269	1291	1269	1291	0.99
5	8	3.5e-06	0.00033	21.9	4.2	1	23	1297	1321	1297	1321	0.92
6	8	1.4e-05	0.0013	20.0	0.9	3	23	1833	1853	1832	1853	0.97
7	8	0.00038	0.036	15.4	2.3	1	23	1859	1883	1859	1883	0.92
8	8	0.0012	0.11	13.9	2.9	1	23	1901	1925	1901	1925	0.93

Sequence Information

Coding Sequence: ATGGAAATCACaggaaacaaatatttacataaaaagtTTAAGAAACAAACAAGCTGTAGTCCTATTTACAACGTAGAAGATAAGAATGATAACGTGTTGATTCCTGTCGTCAGCAACGGCCAATGTGGAGAGATTTATGCACAGAAATTGCTGGAGCATCGAGGATCGACTGAAGCGAAAGctgttaattttttattatttaaagacaATAACTATTTAGGAAGTGTGCCAAATGTCAAGAGTACAAATTATGACGGTAGTTTAGTCACTGATCGTAGCAGCGAATTAGCCGTAGACAGACTTGTGAATGATACATTAGATAATCAGTCTTCCATATCAAAAGTAGCAGTAAGTATAAATGTAGCAACAACATGTAGCAGTGCGGTGACTAGGGAATCAGAAGAATGTAAGAATAAATATCGCATATCTGACGAGCCAAATATCGTCAGACAAACCGAACAGAAACACATGATGAATTTAGTAAAAACCTCAAATGTAACGAGCTGCatatcaacaacaaccactaGTTTATTAGCCAATGAACTAAAAGAAAACATTATAAGAAATTTTAGTTTTGATACCGAAGTTAACATTTCTGAACCAACTACTCAGAAAAATGATAAGTCTTCCATTTTCGATACCgtttattctaaatatagtgTAATATCAGAGCGGCCAAATGCAACAAGTATCAAATCCGATACGGAGGAGGTGGCGAACAAGTCATCGGGTATTATCTATAATAAAAGCGACACTAGCGACAGTGCTCAAAAGCCAGACGCCATCACACCGGAGAAGAAACAAAATTGCCCCGAGCCAAATGGCGGGAAATATGTATGCACATATTGCAACTTGGCCTGTTCGAAGCCCAGTGTACTTCAGAAACATATTCGCGCGCATACCAACGAGAGACCATATCCATGTGTAAGTTGTGGATTTAGTTTCAAGACCAGATCGAACTTGTACAAGCACTGCAGATCAAGAACGCATGCGAACAGGGTCATGGGTAACAAGCATGTACAAACAGGCGCTGGTCAGATGGAAATAATGGACATTGATAACTCTTCCGAGAAGAACGAAGATCGATTAGATTGTGCTGACGAGTACATCGAAGATAAATCATCGAATGAAAAAATGCCGCAATTGTGTGAAAAAATTGCcgaatattcaaaattcaatgtaaataatttattaacatCAGACCAAAGTAAAGTTTGGGAACAAAAATCAAAACCTTATAAACCAAGATTTCATACagcgaaaatattttttgaagaaaataaacTTAAGGAAAACGATTCTAAATTAGATAATGTTACTAGTGCTCATTTCAGAGCTTTACCTAATCCGATTATTAtggaaaatatcaaaaacaaaacagaatcACAAGAGTCACCGAATATCAGATCGAATCCCGATATCTTAAAATTAAGGATAAATGAacttatacataaaaataactcTATTATGAATTGCGATGATGCGGTGGTGATAAGAAGACGAAATGTTGACACAAGCATAGAAAACGTGAACAATAATGACTATATATCACAACAGGTTGTGCATTGGCAACAACCGGCCGAGTACAAAAATACTGTCGATGAACCATTGAATCTTACCGCAAAAAATAGGAAACGCTGCTTAAGTGATTCGGACAACACACAAAAAAGTTTAATCAAAGAACTGTTACTAAAAAATTTAAGTACTGATCCGAATTTACAATGCCCTTATTGCAAAATGATATTCCAAACCGTAACTGAATTAGAAatgcataaattaaaatactgtAATGCGAAAACAAGTAATATACGTTACGCTAGAAGTAGTTCCGTAAATGTGGCTTCCAttttaacacaaaataaaaacgctTTTGACAATATACCCCATATGCAACATACAAcgtttccattaaaatctccaGGTCCGTGCCTGGGAAAAACACGATTGATTGAAAACGAAAAACAAGCGGAAAAGTACCGGACATTTTCATTCGATGATAATGTCATTTTGCATCATACACAATCCGATTCACCCAGTTTTAACAAATACATGCTTCAATCCGCTGTTGGTACTTATCCGTTGTCGCCTCAAATCAAAAAGAATCCTATCCGATTATTCGGTGGTGAAGTAAAAATAACGCAAACATCAGGTGAAACGAGAAGTTTTAAGATTGAATCagaaagtataaataaaatgcaagaAGAACCGCAACATTTCATGGAATTCAATGCGAATTTAAGTGAAAACCTAGTTATAAAATCTGGTTTACACTCGGGTGGAACCGTgctacaaaataaaacaaactacAGTCCGAAAATAGATAGTTTACCTTCGCCGAACATTCTAAGAATGTATGATAATTCAGACATTGTATCGCCAAGTTTAAATTTGCAACTATTAAAGGATAAACCGAAATTTACGTTTGATAACATTACACAACCGAATATGTGTCAAAACGATAAACTATTGAAAATCGCAACAAACGAGCAGTTTACGAAACGAGGATTTCCGTGTCGCGATAAACCAGATACTAACTATAGTGATAATGGGCTACGTCTTTCAGACATTCAACATGACAGtgaaaaagaaaaagaacTCTATAAATCGAATTTAATAGATTTCGGACAAAAAGCGTGTAAATTATTGGCACCAAATTTAAAACCACCAAATATGAAACTCTCTGGTTTGCCAATTTCGTTACCATCCAGCGATAAAATATTCAACACGTTAACCGTTACAATGGCACCATCTGATATTGAGAAGGACATTCCCATCGATAAACAGCATTTAGAGAATTTGAATTTTgcgaaaaaacaaatatcattGCAACAAAAAATGGCCGAAGTTTCTCAGTCCCAGCATGTTTACAATCCAATGAATTTGTTTGTAAATGGAAAAGTAATACCATATGTTCCTGGTATTCCAGGTCCAGTTGTAGATGTTGCAACTGATCATATCTATAATCCCATCGCAATTGGTGCTAGAGCAAAGCATAGTAAAGAAATGCCCAACTCACCTAGACCTATTGAAGATAGTCACGAAGTTAAGGAAAAAGATAATAACACTTCTATATTAAATGCTGCTAATTCGTATGAACGATTAACGCCTACAATTATTGTCGACTCTGCTGAAAATCGGTCAAAATTCGATACTAAATCACTTTCCAATAAAGCATTTCCTAATTTTGATAAACCTGTCGACGTAATAAATAGATTAGTAGAGACGAAAACAACTCCATCTAGTGCAACAGTTTCTAGTCCAGATAAAATGTCATCCAAAGAAGAATCACGGAAATTTGTTCGACCGACAAGCTTAGCCCTAAAGCCAACATTGGGAACATTTAAATCACACCACGGTTTAACACCAACAATGTTCAACCAGGCTTTAATAAGTCCCGATACACCGCGCGTCGCTAAGAAATACTGTCAACAGTACTTGAATGGAAACTATTTTAGTTACCTTGGTTTGAAAAGTTCAACAAAGTCTGTGTATTGTACGTTGAATAAAACACAACCGTTCTatgtgaaacattttaaaaaattaagtatGTATTCCGAATGGAGGCAACAGGAAAGCAAAATTGATAGTTTAAGTGTTAGTGCCTACGATTCTagacagcagcaacagaaatATACGATGGCTGGACATGCGAAGGCGGATTTCATTGCCCACTCAAGTTATAAGTTTATCAAAACCGAAAGCTCATGCACAAAAGAAGATGGTTCAAATAAGAGTAATTCGGTTTTCGGCGGTTACGAGTCAAATGAGGACTATACATATATCAGAGGAAGAGGAAGAGGTCGATACGTTTGTGAACAATGTGGTATACGATGTAAGAAACCATCCATGCTGAAGAAACATATCAGAACGCATTCGGACGACAGACCTTACACTTGCGAACATTGCAACTTCAGTTTTAAGACGAAAGGCAACTTGACGAAACACATGAAGAGCAAAGCACACTCGAAAAAATATGCGGCGACTAGCAGTACTTTAACACAAAACAGCGTTTCCACAAGCTCCGACTCGGATGAAAGTGATGGAGAAAGCAGTGATGAATCTACGCGTCTACAAGAACATGAAGCAGCCCATTGTCTATTATCGTTAGCCCATAAAAACAATCAACCGTTCAATATAATACAAGAAACTAATTCATCAATATCTAGCACCTTTCCTTCTTCAAGTACAACAgtttcaacatttaatatatctgAATTCCCAAATTTTCTAAAAGATGAtaagtttttaaaaaactctgacgaaataagtcaagtaacaaatacaaattttgccaaaaacaaaatactggACGAAACATCGATCAATTTTCACACTTCGAAGCATTTGTCAGAAGCATTTGATACAATACCAAACTCCAGTTCAGAAGTAGTAAATAATGTGTCACAGTATTTAGGTGAATCGGAAAAAATACGACCATTAACATATccatatttacaaacaaaCTTTGATGTTGAAAAAAGTCCCAAAACTACAGAAAGCCGTGTTTACATTTCGAaagaaaaatatcaaaatcaaGAATCAATTACAGCAGCGTCATATTTACAAAGACCGGTTATTAAACACACAGAGTACAACAAAATCGAGGCGACAAGTCAGGATTCGGACACCTTTGAAGCAGTATTTTCCGCAAAATCTGCCGAAGAAGTCAAAACCTGTGTTAAAGTTAACAATTCATTGCATAATTTAGACGGAACTTTACCGACAAATATAGTCTATAGAAAACGAAAATTATCCTCATGTAGTTCACTGTATAAAGTACAAAGAAGTGAAAATGTAGACTCAAATTATAAAGCAGTAGATTTGAGAGTTTTGAGTCAAAATTCTCCAGTTTTAGACTTATCTCCCGTCGCAACATCTGGTGAAACATTTAATGGTTTTTTACACCATCGTGACGAACACAGTGATCATAAAATAGTGCAATCTCATCGAACTTTAATGCTAAATCCAGAAAATCTAACATCAGATGTTTCTCAATCATTAGAAGTGGTTTCTTCGTCGTCTGATCAACAACTATTATACTCCACACCGATAAATGATCGAATATCTGAACCGTTGATTGTATTTAGTACGCAAAAACCGCGCCATAACAGTTTTTCCGAATCGAATAGCAGTGAAACATTCTCTCAAAACAGTGACACCAATGAACGAATTATTGGTAAAATCATTGATCTACCGGAAAGTTCGGATAAAACGAACGATTTGTGCGTGTCAAATCGGCACGCTGATCGTAGCCGTTCGAAAACACCAGATTATCTAGCGGATCCGGATCAATCGGCAATGCAAACGTTGGCGGAAATTGCTATAAAACGtgtaaaattagaaaaaaatattctggCAAAAAATGTTGCGTcggaatatttaaaattggcgCTGAATTGTGATGGTAACAATACGGATGGGAGTTTAAAAAAGTTCGTTGCTGGTAGCAAAGAATCCGTGAACGAGTTAATTGTGAAGCCggaagataataaaaattgttcgATCTGTTCGAAGAATTTCAGCAAACCATCACAATTAAGGTTGCACatgaatattcattatttagaaCGACCATTCCGCTGTGAATCATGTTCCGTCAGTTTCCGTACCAAAGGACACTTACAAAAACATGAACGAAGTGCTAGTCATCATAATAagTTATCGACATCTCCTGCATTATCGTCATCCGAACCTCGGCCATTTAAGTGTACAGACTGCAATATTGCATTTCGTATACACGGACATCTTGCGAAACATTTACGCTCGAAAATGCATATTATGAAATTGGAATGTTTGTCGAAAATTCCCTTTGGATTATATGCTGAACTGGAAAGGGCCAATAGTCTACTAACAGAAATCAATACAACGGACGGAGATCTATGTTTAGAGAGTTTAAAAATACTAGCAAGGAAATTATTCAGTAATGATCCAAATAAATTGGATCAAGTTAATCAATCAGATAGACAAAACAAGCTACCTGAAACGGTACATTGGGGCCCGTATTTACAGCAACTTTCAGAACCGTTTGAGCATGGCGAACAGCCGACTTGGGACGACCGGACCCAATTGTTATATTTCGTTGATATACACAAAGGACTAGTGATCAGTTTCGATCCAATTACAAATGAAATTAATAGTGTCAAATTAGATGGAGATGTAAGTCCTGTTTGCCCTACAAATACTCTAAACAAATTCGTGGTGGGCAACAATAATTCTGTAGTACTTCTGGAATGGGACGGAAAAAACGGGACAGCTCAAAACATCAAAATTCTAGCAACTGTCGATGAAAACAAACCAGGGAATCGTTTCAATGATGGTAAAgttgataaaaacggtcgtCTATGGTGGGGTACGATCGGCTTCGAAAACTCGAGCGGAGTTACACCCGGTCAGGCCACGCTATATAAATTCGTACAAACAAATGTTACGAACCCAACCGTCGAAATTCGGCCTGTTACAAATAGTAACGGGTTAGCGTGGTCGAAAAGTAATACCCAGTTTTATTATATCGATACACCAACTCGAAAAATCGTTGTGTATGATTTCGATCTCGAAACCGGAGTAATTAgtaATAAACAAATCGTGTTCGATTTAGAAAATTATGATATCGGAGGCGTAGCGGATGGCATGACTATAGATCAGGacgataatttatttattgcgtTAAACAGAGGTGGTTTGGTTATTAAGGTGGATCCTAGAAGTGGTATACTGTTACAAAGAATTGCAATACCTGCGAAACGAGTGACTTCAGTTGCTTTTGGTGGTAGACATCtcgatatattatttgttactACGTCAAGatttggATTGACTCCAGAGGAATTGGCGGGCGAACCAGCAGCTGGTAGCTTATTTGCGATTACAGGACTGAAGACTAAGGGCCAATTGGCTAATTACGCTAATTTTTAA
Protein Sequence: MEITGNKYLHKKFKKQTSCSPIYNVEDKNDNVLIPVVSNGQCGEIYAQKLLEHRGSTEAKAVNFLLFKDNNYLGSVPNVKSTNYDGSLVTDRSSELAVDRLVNDTLDNQSSISKVAVSINVATTCSSAVTRESEECKNKYRISDEPNIVRQTEQKHMMNLVKTSNVTSCISTTTTSLLANELKENIIRNFSFDTEVNISEPTTQKNDKSSIFDTVYSKYSVISERPNATSIKSDTEEVANKSSGIIYNKSDTSDSAQKPDAITPEKKQNCPEPNGGKYVCTYCNLACSKPSVLQKHIRAHTNERPYPCVSCGFSFKTRSNLYKHCRSRTHANRVMGNKHVQTGAGQMEIMDIDNSSEKNEDRLDCADEYIEDKSSNEKMPQLCEKIAEYSKFNVNNLLTSDQSKVWEQKSKPYKPRFHTAKIFFEENKLKENDSKLDNVTSAHFRALPNPIIMENIKNKTESQESPNIRSNPDILKLRINELIHKNNSIMNCDDAVVIRRRNVDTSIENVNNNDYISQQVVHWQQPAEYKNTVDEPLNLTAKNRKRCLSDSDNTQKSLIKELLLKNLSTDPNLQCPYCKMIFQTVTELEMHKLKYCNAKTSNIRYARSSSVNVASILTQNKNAFDNIPHMQHTTFPLKSPGPCLGKTRLIENEKQAEKYRTFSFDDNVILHHTQSDSPSFNKYMLQSAVGTYPLSPQIKKNPIRLFGGEVKITQTSGETRSFKIESESINKMQEEPQHFMEFNANLSENLVIKSGLHSGGTVLQNKTNYSPKIDSLPSPNILRMYDNSDIVSPSLNLQLLKDKPKFTFDNITQPNMCQNDKLLKIATNEQFTKRGFPCRDKPDTNYSDNGLRLSDIQHDSEKEKELYKSNLIDFGQKACKLLAPNLKPPNMKLSGLPISLPSSDKIFNTLTVTMAPSDIEKDIPIDKQHLENLNFAKKQISLQQKMAEVSQSQHVYNPMNLFVNGKVIPYVPGIPGPVVDVATDHIYNPIAIGARAKHSKEMPNSPRPIEDSHEVKEKDNNTSILNAANSYERLTPTIIVDSAENRSKFDTKSLSNKAFPNFDKPVDVINRLVETKTTPSSATVSSPDKMSSKEESRKFVRPTSLALKPTLGTFKSHHGLTPTMFNQALISPDTPRVAKKYCQQYLNGNYFSYLGLKSSTKSVYCTLNKTQPFYVKHFKKLSMYSEWRQQESKIDSLSVSAYDSRQQQQKYTMAGHAKADFIAHSSYKFIKTESSCTKEDGSNKSNSVFGGYESNEDYTYIRGRGRGRYVCEQCGIRCKKPSMLKKHIRTHSDDRPYTCEHCNFSFKTKGNLTKHMKSKAHSKKYAATSSTLTQNSVSTSSDSDESDGESSDESTRLQEHEAAHCLLSLAHKNNQPFNIIQETNSSISSTFPSSSTTVSTFNISEFPNFLKDDKFLKNSDEISQVTNTNFAKNKILDETSINFHTSKHLSEAFDTIPNSSSEVVNNVSQYLGESEKIRPLTYPYLQTNFDVEKSPKTTESRVYISKEKYQNQESITAASYLQRPVIKHTEYNKIEATSQDSDTFEAVFSAKSAEEVKTCVKVNNSLHNLDGTLPTNIVYRKRKLSSCSSLYKVQRSENVDSNYKAVDLRVLSQNSPVLDLSPVATSGETFNGFLHHRDEHSDHKIVQSHRTLMLNPENLTSDVSQSLEVVSSSSDQQLLYSTPINDRISEPLIVFSTQKPRHNSFSESNSSETFSQNSDTNERIIGKIIDLPESSDKTNDLCVSNRHADRSRSKTPDYLADPDQSAMQTLAEIAIKRVKLEKNILAKNVASEYLKLALNCDGNNTDGSLKKFVAGSKESVNELIVKPEDNKNCSICSKNFSKPSQLRLHMNIHYLERPFRCESCSVSFRTKGHLQKHERSASHHNKLSTSPALSSSEPRPFKCTDCNIAFRIHGHLAKHLRSKMHIMKLECLSKIPFGLYAELERANSLLTEINTTDGDLCLESLKILARKLFSNDPNKLDQVNQSDRQNKLPETVHWGPYLQQLSEPFEHGEQPTWDDRTQLLYFVDIHKGLVISFDPITNEINSVKLDGDVSPVCPTNTLNKFVVGNNNSVVLLEWDGKNGTAQNIKILATVDENKPGNRFNDGKVDKNGRLWWGTIGFENSSGVTPGQATLYKFVQTNVTNPTVEIRPVTNSNGLAWSKSNTQFYYIDTPTRKIVVYDFDLETGVISNKQIVFDLENYDIGGVADGMTIDQDDNLFIALNRGGLVIKVDPRSGILLQRIAIPAKRVTSVAFGGRHLDILFVTTSRFGLTPEELAGEPAAGSLFAITGLKTKGQLANYANF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01040352;
90% Identity: iTF_01040352;
80% Identity: -