Basic Information

Insect: Nebria brevicollis
Gene Symbol: -
Assembly: GCA_944739395.1
Location: CALYJC010000086.1:60681-63728[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 7.7 7.1e+02 1.9 0.0 3 23 10 30 8 30 0.92

2 15 0.77 71 5.0 2.0 1 23 548 571 548 571 0.89

3 15 0.043 4 9.0 0.4 3 23 635 656 634 656 0.97

4 15 0.0022 0.21 13.0 0.8 1 23 665 687 665 687 0.97

5 15 3.1e-06 0.00029 22.0 2.2 2 23 690 711 689 711 0.97

6 15 0.0011 0.1 14.0 4.7 1 23 717 739 717 739 0.98

7 15 3.5e-05 0.0032 18.7 5.4 2 23 746 767 745 768 0.95

8 15 5.2 4.8e+02 2.4 3.5 5 23 781 799 779 799 0.97

9 15 0.00028 0.026 15.8 3.3 2 23 805 827 804 827 0.96

10 15 0.93 87 4.8 0.1 2 23 843 863 842 863 0.94

11 15 0.00014 0.013 16.8 1.9 1 20 869 888 869 891 0.91

12 15 0.00027 0.025 15.9 0.3 1 23 899 921 899 921 0.99

13 15 0.006 0.56 11.7 7.1 1 23 927 949 927 949 0.98

14 15 5.7e-05 0.0053 18.0 4.5 1 23 955 977 955 977 0.99

15 15 0.00034 0.031 15.6 8.4 1 23 983 1005 983 1006 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	7.7	7.1e+02	1.9	0.0	3	23	10	30	8	30	0.92
2	15	0.77	71	5.0	2.0	1	23	548	571	548	571	0.89
3	15	0.043	4	9.0	0.4	3	23	635	656	634	656	0.97
4	15	0.0022	0.21	13.0	0.8	1	23	665	687	665	687	0.97
5	15	3.1e-06	0.00029	22.0	2.2	2	23	690	711	689	711	0.97
6	15	0.0011	0.1	14.0	4.7	1	23	717	739	717	739	0.98
7	15	3.5e-05	0.0032	18.7	5.4	2	23	746	767	745	768	0.95
8	15	5.2	4.8e+02	2.4	3.5	5	23	781	799	779	799	0.97
9	15	0.00028	0.026	15.8	3.3	2	23	805	827	804	827	0.96
10	15	0.93	87	4.8	0.1	2	23	843	863	842	863	0.94
11	15	0.00014	0.013	16.8	1.9	1	20	869	888	869	891	0.91
12	15	0.00027	0.025	15.9	0.3	1	23	899	921	899	921	0.99
13	15	0.006	0.56	11.7	7.1	1	23	927	949	927	949	0.98
14	15	5.7e-05	0.0053	18.0	4.5	1	23	955	977	955	977	0.99
15	15	0.00034	0.031	15.6	8.4	1	23	983	1005	983	1006	0.96

Sequence Information

Coding Sequence: ATGGACGGAGTGAACGGCAATATTGCGTGCCCTGTGTGCACGCTATTCTTGCGGCCAGGTATGACGCTAGAATCGCATTTGACGAGCCATCCAAAGCAGAAAGTGATTGAGGCGTTAATAAAAGCAGTCCAAATCGGGcaacaaaatattgaaaaaatcgGCGTCCCATGCCAGCCAGCAACAACCGAAATGGCGATCTTTCAACCGATGAACATAAATGCGAACATGGGCCAGCCTGCCGCAAACCAGCACTCGTTCATATCGTACCAACAGTTCATGAGCAGTACTGGCACACCACCTGTTCTCAACACGATGAATCCGCAATACGTTGCCGTGCCTACAGTATTTAATCCTCAAATGATTTGCTCACCGTACATttatcaacaacaacagcaagtTCAGATTGTATCGGCCGCCGCCAATATACAACCGATGATCCCCCGTCAGACTTCAGACATTTTTCCACTACCAACAAACCCGGCAATTTGCACAAACACTAgtgaaatatcaaatattgtAACAAATACTAATAACAATAGTGTCCAAACAACTAAAAACGAAGTGATAACTAGAAACAATTCCCAGCTAAAATTGACTAGCGAAAAATCGTTTAAAACTGAAGATATTACAATTATTGAAAGTGTTTGTGAAACAAATAgtcaaaatgttttaattgttaataattataatgatgCAGATGAGAATACCAGTTTACAAGCAGAGACAATTGAATGCTTAACACCATTTGATGAAAACGATAtgcaaattcaaattgaaTGTGCTTCTTTTGATGATAAGTCGATTCAAATAGATAATAAACAGCCGGAGGAACCAGAATGTATTGAGATCGAAGACGACGATCAATTAACAGATAAAATTGATGAATGTGACACGGTTGAAGAAAATGATTGGGATACCAAACAGACTGACGAAGAACTTAATAAAGCCTGCCAGACCACAATTGACGAGGCACTGGTTGACGAAAAAATGACTTTAAACGTTGATGAGAAAAAGAGTTATAATGCTATCGAAAATCCTGATGAAATTAAAGATGTTAATGACGTAGAATCTGATAATCACTGTTGCACAGAAGACGCCGAACATATAGCATTCATTGATATGGATgacatcaattttattttacctaatGATATGATCCAAAATGGACAGTCGATTATTTCAAAAGTTGATGATATTGAATGTTATAACGAAGCCAACAGAGATGATAGACCACAGAAGTTGATGATTATTGGAAATGAGGTAGTATGTAAGGGTCCAGTAAGTGAAGAGAATGAAAATTGCATGATAGATCATTATGATATAGAGGATAGAATGGATGATGGAAGTGTATCGCAGGAAAGTTTGAATATCCGAGCAGACGAGCGAATGCCTCCACGGGGAGAACTATCCGAGCAAGAGAGCAATGGCGCTAGTGAACTTGGTTGGGGTACTAGGATTTATCAGGAGGGCAGCTCAGGCATGTCAACATCATATGATTTGATGGCGAGAGAAAGTTGGGGCGAAGCATCCGATTATTCAGATTCTGAAGCAGCTGTTTTACAAAGTCGAATGCCACCAATGAGTGACGAAGTTCACCAAGACGATGATGAAGAAGTGGACAAGAAAAATATTCCCCTTAACTTCGATTGCACAACATGTGGCGCATCTTTCCGTTGCCCAAAAGAACGACGCGTTCACCAAACACAAGAACACACATCTAAATCACCGATTAAAAAGCGACTACTTAAGAAACGCAAAGTTGGTTTACTAAGTCCAAAAGTTGAAGACACCAAGGAAGAAACTAGTGACATAGACGACCCACTATCAGAGTCAAAACTAGCGGAAAcaaaagtagaaaatataaacGTTTTACAACCAATAGAAGTGAAAGAGAGtatattatgtaatatttgtGGTGAATTATTAACGTCATTGAGAGACTTAACAGTACACAATAGAAGGAAGCATAAACTCCGAAGACCAACATTATCGCATTCATGTAAAATTTGTGATATGATATTTCCCTCTGAGATAAAATTCAcagaacatttaaaaatacaccCGTTAGAATGCCATATATGTGGGAAAAACTTCTATAGGATTTCGAATTTACGTCTTCACCTTAAGCGACATTTGGGCCTAAAACCGTACAAATGCGAGGTGTGCACGAAAGGGTTTATAACGAAACAGAAACTTCGTGAACACCACCACATTCACACTGGTACAGCGCCGATCAAATGTACCATGTGCGACGAGACGTTTCGGCGGCATTCCAATCTAGTGCAGCATCGCAATCGACATCATTTAAACATCAAGAAAAAACTCAAAGACTTTGTATGTCATTGCGGTGAAATATTCCACTCGACAAATAAATTCAACTGGCACAAAGAAACGCATGATTCGAAACCAAAATCGTGTAAGTTTTGTTACGAGAAATTTATACATAAAGCGAGTTTAACGAGGCATATTCGTCGAGCGCATAATCAGAGATATGTGCCCGAAGAGGCTAGAGATAATGAGAATGTAGAGTGTGAAATCTGTAAAGGTATTTATTTGCGATCGAGTTTAGAGGCGCATTTGTATACTCATTCAGGGAAACGGCAGCATTCATGTCCTATTTGCAGTAAAGAGTTCACAACAAAATGGAATTTAAAGTTGCACAAATGGACGCATGCGgctccaaattcaaaaccctATAAATGTGATTTGTGCCAAAACGCGTTTATACGCGAAGCGGATTTCATTTCGCACATGAATTCACATCGCAAAGTGCGCCCGTATACGTGTAATTATTGCGGATGTAAATtcattagaaaatataattgtttgcGGCATGTACGCGAGCATGAGGAGGGGAAATCGTACAAATGTACCGTTTGTAGTAAACTGTTTCACCGGTCCTACTACCTCAAGGAACACATGAGGGTGCACAGTGGAATTCGGCCATTTACTTGTCACATTTGCGGCAAAACATCCACGACCAAATCCAATCATAATAAGCATATGAAAATCCATCACGCCCGCGAACCCGTAAGCACTGAGGgttag
Protein Sequence: MDGVNGNIACPVCTLFLRPGMTLESHLTSHPKQKVIEALIKAVQIGQQNIEKIGVPCQPATTEMAIFQPMNINANMGQPAANQHSFISYQQFMSSTGTPPVLNTMNPQYVAVPTVFNPQMICSPYIYQQQQQVQIVSAAANIQPMIPRQTSDIFPLPTNPAICTNTSEISNIVTNTNNNSVQTTKNEVITRNNSQLKLTSEKSFKTEDITIIESVCETNSQNVLIVNNYNDADENTSLQAETIECLTPFDENDMQIQIECASFDDKSIQIDNKQPEEPECIEIEDDDQLTDKIDECDTVEENDWDTKQTDEELNKACQTTIDEALVDEKMTLNVDEKKSYNAIENPDEIKDVNDVESDNHCCTEDAEHIAFIDMDDINFILPNDMIQNGQSIISKVDDIECYNEANRDDRPQKLMIIGNEVVCKGPVSEENENCMIDHYDIEDRMDDGSVSQESLNIRADERMPPRGELSEQESNGASELGWGTRIYQEGSSGMSTSYDLMARESWGEASDYSDSEAAVLQSRMPPMSDEVHQDDDEEVDKKNIPLNFDCTTCGASFRCPKERRVHQTQEHTSKSPIKKRLLKKRKVGLLSPKVEDTKEETSDIDDPLSESKLAETKVENINVLQPIEVKESILCNICGELLTSLRDLTVHNRRKHKLRRPTLSHSCKICDMIFPSEIKFTEHLKIHPLECHICGKNFYRISNLRLHLKRHLGLKPYKCEVCTKGFITKQKLREHHHIHTGTAPIKCTMCDETFRRHSNLVQHRNRHHLNIKKKLKDFVCHCGEIFHSTNKFNWHKETHDSKPKSCKFCYEKFIHKASLTRHIRRAHNQRYVPEEARDNENVECEICKGIYLRSSLEAHLYTHSGKRQHSCPICSKEFTTKWNLKLHKWTHAAPNSKPYKCDLCQNAFIREADFISHMNSHRKVRPYTCNYCGCKFIRKYNCLRHVREHEEGKSYKCTVCSKLFHRSYYLKEHMRVHSGIRPFTCHICGKTSTTKSNHNKHMKIHHAREPVSTEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01040338;
90% Identity: iTF_01041192;
80% Identity: -