Nbre006206.1
Basic Information
- Insect
- Nebria brevicollis
- Gene Symbol
- -
- Assembly
- GCA_944739395.1
- Location
- CALYJC010000089.1:701189-705704[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0057 0.53 11.8 1.3 1 23 252 275 252 275 0.95 2 14 0.25 23 6.6 5.9 2 23 344 366 343 366 0.96 3 14 0.04 3.8 9.1 0.4 1 23 375 398 375 398 0.97 4 14 0.0065 0.6 11.6 0.3 1 23 404 429 404 429 0.97 5 14 0.00071 0.067 14.6 0.4 2 23 440 462 440 462 0.96 6 14 0.016 1.4 10.4 0.4 1 23 498 520 498 520 0.97 7 14 8.7e-06 0.00081 20.6 0.8 1 23 526 548 526 548 0.98 8 14 7.8e-08 7.2e-06 27.1 5.6 1 23 553 575 553 575 0.98 9 14 0.00046 0.043 15.2 3.6 1 23 581 603 581 603 0.98 10 14 9.6e-05 0.0089 17.3 4.9 2 23 610 631 609 631 0.95 11 14 5.3e-05 0.0049 18.1 0.3 3 23 639 659 638 659 0.97 12 14 0.0013 0.12 13.8 0.5 5 23 668 687 667 687 0.93 13 14 0.044 4.1 8.9 0.9 1 23 696 718 696 718 0.96 14 14 0.01 0.94 11.0 0.9 2 23 725 747 724 747 0.93
Sequence Information
- Coding Sequence
- ATGGAGAACGATCCTGTAGTAGTACccgaaaaaatattattaaacaaagtTCCTATACAAAATCGTTTAAAACTTGATGTGAAAAAATCGCAAAAAATTCGCAAAACCGTaacagatattgaaacaatcTCGAAAAAATCACAACACGCTGTTGAATCATTGCGTGAACCAAACACAAAACTAACCATCGTAGAAAGAGCGCTTGGTAAATTTAACAGTGAACGAGATGAAATGGCCGCAAAATCCTGTTTTAATCAATCGCTTCGCGAAGGACCACCGTTCGTTTGCAAAATATGCCATACATGGTTCTCAGTGGAGTTTCACCATTATAAAGCGaatatcatgaaaaatttcacgGATTCCTTATTTGAAGTCACagaaaatgacaaaaataacaacatcGTTATCTGTTGCCTTTGCGACGAAAACATCACGCTACTTATCAAATCCGTCGAAGATATTTTCGCACACTTCAATCAAATACATTCCGTATCATTAAAACGAATCAATCAACTAATAACGCAAAAACCAGTGTTGGAGGAATATGATGAGTTTTATCGCGAAATTAACGACGAGATACAAACAGACTTAAGCCATGAAATACCAAGTATGATCGCACCTGACGATGAAATGGAATTAGATGATTTAGAAGtgcatttaaattatttagattCAGAGTTTACGCAAGATATTGACCCGCAACACATTGAAATCCTTTACGATTATTATTCGGATGAGTTGAGCGAAGGGAAACATAAATGCGAGTTTTGCAATGAGGATTTTGTTGTTGTGTCTGATTTGATGCATCATTTAAAAGATGCGCATCGCgtgaaatcaaatttgaagGAGACGAAATGTGACAAATCGTATCGACATATTTTACAAACGCATTCGCAAGAATTACATAAACATGATGTACAAACAATAGGGCTTAAATGTCGATATTGCGAACAGCGATATTGGGAGCGAATTTTATTGAATGACCATGAAATTCAGATGCATTTCGAGGATAACTCAAACgattttcttaaatgtttcAAGTGTCTTACAGTATTTAGTAACCAGaattGCCTTAGTGAACACACCAAAATTTGCCACGAAGCCCTATTTACACACCTCACCTATAAATGTCTTCAATGCACCGTAGCATTTCCAAACATCGAATTAATTAGGAAACACTTCCGTTCGGAGCACTCCAACCTAAAAGTATACGTGTGCCCAGTGCCAGATTGTCACAAAACTGTCCTGCGCATAAAATCACTCAAAAATCATCTCCGTATGCCACACACAGCCAAaaagaaatcaaataaatGCGAATCTTGCGAGATCTGCGGGAAAGTATCGAAAAACCAACGATCTGCTACGATACACATGTTGATGAAACACCGCCGAGAAAAAGCTGGCTTTCAATGCAGATTATGCCGCGATCGTTTTCCTACCATTGAACTACGCAAACTTCATTATGCAACAAAACATTCTGGAGAGTTCGCGTACTCTTGTTTGTTATGTGGTAAAGGATTTTTAAGCAAATCTGGCTTATATGGCCATAAAAAAATTCACCAGAAAAACGAATTTTATGTGTGTGAATATtgcaacaaacaatttattcgTAAAGATTCATATAATGAGCATTTGTTGATACATATTGGACCACGGCACCAGTGTCCACATTGCCAGAAAACGTTCACGCAACGTTCGAATCTTACTCGTCATGTTCGTATTCACACCGGGCAAAAACCGTACTCATGCAGTTATTGCGATAAGAAATTCAGTGATCAAGGATCTTGCAGATCTCATGAACGAGTACATACAAAAGCAGAGCACTGTGAGTGTTCGTATTGCGGGAAGAAATTTAGTAAAtggcaaaaattaaaataccatATAAAATTCCATACAGGCGAAGGTTTGGTTGATTGTGAAGTGTGCGGCAAACAATTTTCGAACTCGTACTCATTAGGTGAACATAGAAAAATACATAATCAACAAACGTTAGTGATGTGCAATTGTGGTCGGGGTTTTAGCAGCGAGAAATATTTGCAAAGACATATGATTAATGTTCACGGTGACCCACAAAACACCACCAAATATTTGTGTCCTATTTGTTACAAACCACTATTACACAAATCATCATATTTAAGTCACATTATGACGCATGCTAATGTTAAACATATAAAATGCACATTATGTGATAAAGAATACCAAACTCGACGAACCGTTCGCAAACACCTAATCGAACAACACAACCTAACACCTACGAGTGACTTAAGCACCTATTTCAAAGAATTAACACCGCAAGAAGTTGGTTTAAACGTACCACCAGCAGCTGAAATGGCAACAGTAAACTGCAATGATTTGCTAGACGATGCAAGCGTATTACGAATTAACATTTCACAACTACAACCACTAGAAAAGACGGTCGAAATAACCGAGTTAGAAGGTAAACATAATGACGCTAATATCAAAGTGGAAGTTATTAGCGACGAAGATGATACTTCATTGATGAGTAGAATGAAAAGAAAAGAGAAAACACCTATTAAATACAGTTTAAATAAATGGAAGAAACAAATGATTATAGATGATTTTGAAACATCTAGCGATGATAGTGAGTAA
- Protein Sequence
- MENDPVVVPEKILLNKVPIQNRLKLDVKKSQKIRKTVTDIETISKKSQHAVESLREPNTKLTIVERALGKFNSERDEMAAKSCFNQSLREGPPFVCKICHTWFSVEFHHYKANIMKNFTDSLFEVTENDKNNNIVICCLCDENITLLIKSVEDIFAHFNQIHSVSLKRINQLITQKPVLEEYDEFYREINDEIQTDLSHEIPSMIAPDDEMELDDLEVHLNYLDSEFTQDIDPQHIEILYDYYSDELSEGKHKCEFCNEDFVVVSDLMHHLKDAHRVKSNLKETKCDKSYRHILQTHSQELHKHDVQTIGLKCRYCEQRYWERILLNDHEIQMHFEDNSNDFLKCFKCLTVFSNQNCLSEHTKICHEALFTHLTYKCLQCTVAFPNIELIRKHFRSEHSNLKVYVCPVPDCHKTVLRIKSLKNHLRMPHTAKKKSNKCESCEICGKVSKNQRSATIHMLMKHRREKAGFQCRLCRDRFPTIELRKLHYATKHSGEFAYSCLLCGKGFLSKSGLYGHKKIHQKNEFYVCEYCNKQFIRKDSYNEHLLIHIGPRHQCPHCQKTFTQRSNLTRHVRIHTGQKPYSCSYCDKKFSDQGSCRSHERVHTKAEHCECSYCGKKFSKWQKLKYHIKFHTGEGLVDCEVCGKQFSNSYSLGEHRKIHNQQTLVMCNCGRGFSSEKYLQRHMINVHGDPQNTTKYLCPICYKPLLHKSSYLSHIMTHANVKHIKCTLCDKEYQTRRTVRKHLIEQHNLTPTSDLSTYFKELTPQEVGLNVPPAAEMATVNCNDLLDDASVLRINISQLQPLEKTVEITELEGKHNDANIKVEVISDEDDTSLMSRMKRKEKTPIKYSLNKWKKQMIIDDFETSSDDSE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01041194;
- 90% Identity
- -
- 80% Identity
- -