Nbre003143.1
Basic Information
- Insect
- Nebria brevicollis
- Gene Symbol
- -
- Assembly
- GCA_944739395.1
- Location
- CALYJC010000028.1:1111454-1112797[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.00049 0.046 15.1 1.7 1 21 126 146 126 147 0.92 2 9 3.1e-06 0.00029 22.0 0.7 1 23 191 214 191 214 0.98 3 9 0.00021 0.019 16.3 2.1 1 23 250 272 250 272 0.98 4 9 1.1e-05 0.00098 20.3 0.2 1 23 278 301 278 301 0.97 5 9 8.9e-06 0.00083 20.6 0.2 1 23 307 329 307 329 0.98 6 9 1.5e-06 0.00014 23.0 0.5 1 23 335 357 335 357 0.98 7 9 0.00034 0.032 15.6 0.6 1 23 363 385 363 385 0.97 8 9 1.2e-06 0.00011 23.3 1.8 1 23 391 413 391 413 0.98 9 9 7.5e-06 0.0007 20.8 2.2 1 23 419 442 419 442 0.95
Sequence Information
- Coding Sequence
- ATGCGTAGTAAAACGCGCGTTTATGTTCGCAGGCGAAACGACACCGCAAGTCTGAGTCCATTTCGCCAAGACGACGTTGAAGTGAAGATAGTCATTCCATCCAATATCACCCCACCTAGAAAACGTGGCCGTAAACCCAAACACCAAACGCAAGAAAATAAAGACGATACCGTCAAACTTGAACCGTCATCCAGTGACACGGATGGCCAATGGATTAAAACCGAACTAGTAATGGAAACAGACGACGCCATCAATCCCTTCATTGCCGATTGCGAACTAACAGAAGACATGGATGTGAAAATAAGTCCACCCATCTCTGATTCCGATGACTTAGATCCCGAATACGATCCTGGTAACGAAACCAAAGTGAAAACACACCATTGCGCCACGTGTGGCAAATCATTTCGGAAAATTGTCCAATTACGGCGCCATGAGAAATTATGCTCTAGTGAGTTGAAAGAAGAATTATTTAAGGAAGAGTATCTAGATGGGGATTTAGATGATTTGGATAGAGATCCAATGGATGAGTTTCAAGATGCGGAAATATTTGAGCGAAAAGTCAAACGGGAATATCGGTGTGATTACTGCCCGAAAATGACTGTACGCCGTGAGGATTTGAAGGATCATGTCCGGACGACTCATCCAGAAAAATTCGAGAGTTTTTCAATGCAAAGGCAACGGAAACGCAGTAAAATCGATCAAGAAGCAGTGAATCGCGCTAAAGTCGTGGTGGACTCGCGTACTTATTACCATTGCAGTGATTGCGGTAAAAATCTCCACTCGCCGTACACGTACATCTGGCATATTCGCATTCACACCGGTGAGCGACCATACGTTTGTGATTTATGCGGTAAACAATTTCGTGTTTCACAAGGTTTAGTGCGACACCTACGCGAAACACACGCCGGTATCAAGAACTTCCCGTGCGATCTATGCGGTCGCATGTTTGCGACCAGACGTAACGTTGAAGAGCACAGGCGTATCCACACGAACGAACGCCCTTATATTTGTGACTTGTGCGGCAAAGCTTTCAAACAAAAGGCATCGTTGTTCGTGCACAATCGTTCGCACACAGATAGTTTCCCGTTTAAATGTAGCTATTGCAATCAAGGTTTTCGTACACGACCACCGTTGTTAGTTCACGTGACGCGACACACGGGCGAAAAACCGTACCCGTGTGATATTTGCGGGCGGTGTTTTCGCATTAAATATGAGCTAAAGCGGCATAGATTAATCCACTCCGATGATAAACCATTTAGTTGTACGGATTGCGGATTGAGTTTTCGACAGAAACGGTACTTGAGGaatcacaataaaattaatcataatCGGCCGACACCGTAA
- Protein Sequence
- MRSKTRVYVRRRNDTASLSPFRQDDVEVKIVIPSNITPPRKRGRKPKHQTQENKDDTVKLEPSSSDTDGQWIKTELVMETDDAINPFIADCELTEDMDVKISPPISDSDDLDPEYDPGNETKVKTHHCATCGKSFRKIVQLRRHEKLCSSELKEELFKEEYLDGDLDDLDRDPMDEFQDAEIFERKVKREYRCDYCPKMTVRREDLKDHVRTTHPEKFESFSMQRQRKRSKIDQEAVNRAKVVVDSRTYYHCSDCGKNLHSPYTYIWHIRIHTGERPYVCDLCGKQFRVSQGLVRHLRETHAGIKNFPCDLCGRMFATRRNVEEHRRIHTNERPYICDLCGKAFKQKASLFVHNRSHTDSFPFKCSYCNQGFRTRPPLLVHVTRHTGEKPYPCDICGRCFRIKYELKRHRLIHSDDKPFSCTDCGLSFRQKRYLRNHNKINHNRPTP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00873271;
- 90% Identity
- -
- 80% Identity
- -