Nbre013769.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nebria brevicollis
Gene Symbol
-
Assembly
GCA_944739395.1
Location
CALYJC010000258.1:253207-261524[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00097 0.09 14.2 0.1 1 23 187 209 187 209 0.97
2 12 2.9e-06 0.00027 22.1 1.8 1 23 215 237 215 237 0.97
3 12 0.065 6 8.4 1.4 1 23 256 279 256 279 0.95
4 12 8.8e-06 0.00082 20.6 4.0 1 23 290 312 290 312 0.97
5 12 9.2e-06 0.00086 20.5 0.2 2 23 319 340 318 340 0.97
6 12 1.2e-07 1.2e-05 26.4 3.2 1 23 345 367 345 367 0.98
7 12 2.1e-06 0.00019 22.6 0.1 1 23 373 395 373 395 0.99
8 12 5.1e-05 0.0048 18.2 6.3 1 23 401 423 401 423 0.98
9 12 0.00011 0.011 17.1 0.6 1 23 429 451 429 451 0.98
10 12 0.00038 0.036 15.4 1.9 1 23 457 479 457 479 0.99
11 12 0.0006 0.056 14.8 6.0 1 23 485 507 485 507 0.98
12 12 5.7e-05 0.0053 18.0 0.8 1 21 513 533 513 534 0.96

Sequence Information

Coding Sequence
atggaaaaatatattactgtaacgaattattataatatatgtcgTGCGTGTTTAAATGAAAAATCAAATATGAGACCGGTTATCGAAGCTTGTGTTCCGAATATGATCATGTCTTGCACTTCTGTTATGATAAAAGAAAACGATGGACTGCCACAACAAATCTGTATCCAGTGTCTTCAGCAAATTAACCGTAGTTTTACATTTAAACAATTGTGTGAGAAATCCGATGCAGCATTGCGACagtttttaatacaaaatccGGAATTAAAGCCATCTATAGAAGACATTAAAGATGAAAATAAAGGAGCTTGCGTTATACAAAACATCACCGATTTTACGGATTCTATGACAATAAATTCATCTGTTGAGATAATACAAGtcgaagaaattaataatgcTCAGCTGACAACATTACAAGTTTTAAATGACGCTACTTGGGGGATAAAAAATTTCGAAGAAATAAATGAAGTGCGGCAAGTTGACCTTGAAggagaaataaatgaaattaatcaaGAACCTAAAGAAGAAGATGACTTGAATCGCACGGAAGGGGAAACTTTCGAATGTTTAACatgcaataaaatatttgaagcaaAATGGAAATTAGCGGCACATATGAAGGGCCATACAGGTCAAGGGACTCATGTATGCCCTGTTTGTGGTAAACGATGCAGTATTCCATCATTGCTTAAGAAACATATGAAAATCCATGCGGCTGGTCGTACGCAACAGATTCAAGAACGAAGACGCATGAAAGATAAACCACACCGGTGTGAGTTGTGCAATAAAGGATTCCTTGGTGTGGAATCGCTACGCAAACATACGCGCGAGCAGCATTTCGGTGAGAAAAGGATCTACGAGAAGAAGCATATGTGCACGGCTTGTGGAAAAAAATTTTGCAACAGCAGTTGGTTAGAGATACATATGCGTAAACATACTGGCGAACGTCCGCTTACATGTGAAACCTGCGGTAAAACATTCGCGATGCCTTCATCGCTAAGTAAACACGCGCTCACGCACTCGGAACCCCGGCATCGATGCACCGAGTGCGGCAAAGCGTTCACGCAATCGTTTCAGCTGACAGTGCACATGCGCAAACACAGCGGCGAACGGCCTTACGTGTGCGGTGTATGCGGCAGAGGTACAACCACTAGCGAAGCGTTAACCGtgcacatgcgcacacacactgGCGAACGACCATACCACTGTCACCAATGTGATCACGCATTTGCaagTAGAAGTCAGTTAACGATTCACCTACGACGTCATGCCGGCCAAAAACCTTATTCATGTACAAATTGTGGCCGTGCTTTTCTACAGAAAGGAGACTTGGATACGCACATGCGTTACCATACCGGCGAACGTCCCTACAAATGTAAATTATGCCCGAAACAATATTTTGCGCATAGTGCCCTGCGCGTCCATATGATGAGTCACACGGGCCTGAAACCGCACAAGTGTGACCTATGTCAGAAGCGATTCGTAAGTTCTCACATTCTCAAAACACACATGCGCACTCACACGGGCGAGAAACCATATTCATGCCACGTATGCGGGCACAGATTTTCGCAATCGGGTGCCTTAAGTACCCATCTAAAGGGTGCATGTATCGAAAAATCGAAAGTGTGTAATCAAATTGATGATTGCCTTGATGCTTCCGATGAAACTCCATTCGTATGCAGTGAAAAATCTAGCCCTATTTATGAAGGTTGTGGTTACAGTGATTATGTAAAGGATAATGGACCGTTTCCCTGGACTATTAAATTCTATGTGATTAATGATTTTGATGGTATTGATGAAGATTACACATACGTAAAAGAAGAGTGGGAACATTATTGTTCGGGTACACTTGTAACACCGAATATCGTGATAACAGTTTCGGAACTCTCAAAAATTTGTGGAAAGTTTAAAGATGACGGTGTTGCACCATATCCATGGCACGCAGCCATTTGGTCAGAAAGAAATACGTCACCAAAACGAATATGTGCTGGTACAATTATTGCTCCAAAATATATTGTAACAGcTGCATCATGTTTTTGGGATTTTAAGAATCAAAGATTTCTTGATTCTCTTTTGGACACATATACAGTTTCATCAGGATTCAATGGGGAAACTTTTGAGCAATTCAGTAATgTATTCCATGTGCATACCGACAATTATCTATGGGAATCAAATGGACAAAGTGatgtaaataatttagcaATTGTTGAAACTGAGAGTGATTTTCAATTTGATGGACTTGTGCTGCCTGCATGTATTGATTTCgaagaagaaaatattgaaaatatattcgcAACAAGAACGGCAATTATGATTTCGTGGTTAGTAAAAGGTGCTTCAAAAAATTATACTCCTGGTCAACTAAGGGCATCTTTTTTATCAGAGGAAGTTTGTAGAGAATATCTAAATGATAGATGTACGGACTGCAAAGGAGAGGTTCCCGGTGATAATTCGAAATTATGTTTAAGTTACGATGTTCCATGTAATAAAAGCACTTGTATTGGCTATATGTCTGTTTGCAACTCCGAATGCGAATGTGATAATTGTGACGATGAAGACGAACAAATGTGTAATTTAGAATCAACACCAAGGCTAGTTGATGATTGCGGCGAATTTGATCAAGATACTGGTGATAAACCGTGGCGCTCAGCTTGTGAGTTGGGCGAGGGGAAATTTATATGGAAGAAATAG
Protein Sequence
MEKYITVTNYYNICRACLNEKSNMRPVIEACVPNMIMSCTSVMIKENDGLPQQICIQCLQQINRSFTFKQLCEKSDAALRQFLIQNPELKPSIEDIKDENKGACVIQNITDFTDSMTINSSVEIIQVEEINNAQLTTLQVLNDATWGIKNFEEINEVRQVDLEGEINEINQEPKEEDDLNRTEGETFECLTCNKIFEAKWKLAAHMKGHTGQGTHVCPVCGKRCSIPSLLKKHMKIHAAGRTQQIQERRRMKDKPHRCELCNKGFLGVESLRKHTREQHFGEKRIYEKKHMCTACGKKFCNSSWLEIHMRKHTGERPLTCETCGKTFAMPSSLSKHALTHSEPRHRCTECGKAFTQSFQLTVHMRKHSGERPYVCGVCGRGTTTSEALTVHMRTHTGERPYHCHQCDHAFASRSQLTIHLRRHAGQKPYSCTNCGRAFLQKGDLDTHMRYHTGERPYKCKLCPKQYFAHSALRVHMMSHTGLKPHKCDLCQKRFVSSHILKTHMRTHTGEKPYSCHVCGHRFSQSGALSTHLKGACIEKSKVCNQIDDCLDASDETPFVCSEKSSPIYEGCGYSDYVKDNGPFPWTIKFYVINDFDGIDEDYTYVKEEWEHYCSGTLVTPNIVITVSELSKICGKFKDDGVAPYPWHAAIWSERNTSPKRICAGTIIAPKYIVTAASCFWDFKNQRFLDSLLDTYTVSSGFNGETFEQFSNVFHVHTDNYLWESNGQSDVNNLAIVETESDFQFDGLVLPACIDFEEENIENIFATRTAIMISWLVKGASKNYTPGQLRASFLSEEVCREYLNDRCTDCKGEVPGDNSKLCLSYDVPCNKSTCIGYMSVCNSECECDNCDDEDEQMCNLESTPRLVDDCGEFDQDTGDKPWRSACELGEGKFIWKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01041123;
90% Identity
-
80% Identity
-