Basic Information

Insect: Nebria brevicollis
Gene Symbol: -
Assembly: GCA_944739395.1
Location: CALYJC010000014.1:290319-292197[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0029 0.27 12.7 1.8 1 21 249 269 249 273 0.92

2 11 0.33 31 6.2 0.7 2 23 282 302 281 302 0.95

3 11 0.0041 0.38 12.2 0.7 1 23 308 331 308 331 0.95

4 11 6.3e-07 5.9e-05 24.2 0.7 1 23 337 359 337 359 0.99

5 11 7.5e-08 7e-06 27.1 0.5 1 23 365 387 365 387 0.97

6 11 1.5e-06 0.00014 23.0 0.3 1 23 403 425 403 425 0.98

7 11 0.00027 0.025 15.9 0.4 1 23 430 452 430 452 0.95

8 11 1.2e-06 0.00011 23.3 1.2 1 23 458 480 458 480 0.97

9 11 5e-06 0.00046 21.4 4.8 1 23 486 508 486 508 0.97

10 11 2.8e-08 2.6e-06 28.5 0.2 1 23 514 536 514 536 0.99

11 11 3.9e-05 0.0036 18.6 1.6 1 23 542 564 542 564 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0029	0.27	12.7	1.8	1	21	249	269	249	273	0.92
2	11	0.33	31	6.2	0.7	2	23	282	302	281	302	0.95
3	11	0.0041	0.38	12.2	0.7	1	23	308	331	308	331	0.95
4	11	6.3e-07	5.9e-05	24.2	0.7	1	23	337	359	337	359	0.99
5	11	7.5e-08	7e-06	27.1	0.5	1	23	365	387	365	387	0.97
6	11	1.5e-06	0.00014	23.0	0.3	1	23	403	425	403	425	0.98
7	11	0.00027	0.025	15.9	0.4	1	23	430	452	430	452	0.95
8	11	1.2e-06	0.00011	23.3	1.2	1	23	458	480	458	480	0.97
9	11	5e-06	0.00046	21.4	4.8	1	23	486	508	486	508	0.97
10	11	2.8e-08	2.6e-06	28.5	0.2	1	23	514	536	514	536	0.99
11	11	3.9e-05	0.0036	18.6	1.6	1	23	542	564	542	564	0.95

Sequence Information

Coding Sequence: ATGTGTGAAGATACGAAAGAATTAACAATTTATGATTTTGATAAAGTGTGTCGTACTTGTTTGGCGAAAGGTGTAATGAAACCGCTCTATGAAAATTGTTCCGAAAATGTTTGCTTAATTGAAATGTTAATGTCTTGTACTTTTGTCcagtttacAGAAAATGACGGCTTACCGGTGCAAATATGTAACGAATGTAttctacaaataaataaatcgtacGATTTCGCAAATAAATGCCAAATTGCCGAAACGAAATTGCGAAAATGTGTAAACGAATTCCagagtaaattaaataagaacACCGCAAAACAACCGCCAAATGTTGCATTACGACGTACACGCAACCTTAGAACACAAAAAACACCAACTCTCGTAATAAAAGACGAAATATTGGAATCAAATTCAATTACGGTTAAACATGAAGTACCTCTTACGGAAGTTGATGAACTTTGTGTTAAGGACTCTTTAAGTGTTAAGTGTGAAGCTAGTTCCGAATTACAACTAAATGGCGGTGTTAAATCTGAAGATAGTGATGATTCagatagtaaaaataatatagaacAAGCAAGCAGTGAACTTATAATTAAGTCTGAAGATAGTGATGATTGTTTGGCGAATTACGTGAAGAAGAAGTTACtgcgaaaaacaaaaaaagccATCGAATCTGATGATAGTGATAATTCAGTGCGAAAACACCCAGCGcaaaagaataaaatactgCATAAACTAAAATCGCAAACTTCGTACGAATGTAAAAAATGTGATTTGAAATTCGCCAATTTTCAACTATTAAAGTTGCATCGTCAAGACAAGAATCACCCGCGCAATGGTTACGGCCGCAAGACTTGTAAAATTTGCGCGAAATCCGTCGGTTATTCGCGAATGAATCAACACATGCGTATACACACGCGCGAAAAACCGTACTGCTGCGACGCTTGCGGCGCTCGCTTTAGCATCGGCAGTAATTTGCGACGTCACAAACTATCAGCGCACTCGAACGAAAAACCGTACCGTTGCGACCAATGCGGTCGCGGTTTTACGCGATTAAGCCTATTAAAAGATCATGGGAGAACGCACACTGGCGAAAAACCATATGTTTGCAATTATTGCGGCAAATCGTTTGCGCAGGCGTCCAGTTTGCGCACGCATCTATTCGTACACGCAAAACGCGGTGAGACTGAAGCGAGCGACATTTCGCTACATATGCACCAATGTCCGGATTGCGAACGCAGCTTTGCAACAAAACCACTACTGCGCGCTCATCTGTTAATCCACGGCGAAAAACGTTTTCTGTGCAGTGATTGTGGCCGCAGTTTCATCAGCATGATTTTGCTTAAATCTCACTCAAAAGTACACACGGGCCTCAAACCGTATACGTGTTCGGTGTGCGGCAAGACGTTCAGTCACGCCGGTTCGTTGAAGTCACACTCGTTAATACACACCGGTGAGAAACCGTTCGCGTGTACCGTTTGCAATCGATCGTTCACGCAACGCAGCCACCTGAAGTATCATTCGCGTACGCACAGCGGCGAACGGCCGTACGTGTGCTCGGTGTGCGGCAAAACGTTCGCGTTAAACGGCAACTTAACCGTGCATATGCGAACGCACACAGGCGAAACACCGTACTTGTGTCCCGTATGCGGGAAAGGCTTCCACGATTCTAGCTCGatgaaaaaacataaaaaaggCCATGGACCACAagatgtttga
Protein Sequence: MCEDTKELTIYDFDKVCRTCLAKGVMKPLYENCSENVCLIEMLMSCTFVQFTENDGLPVQICNECILQINKSYDFANKCQIAETKLRKCVNEFQSKLNKNTAKQPPNVALRRTRNLRTQKTPTLVIKDEILESNSITVKHEVPLTEVDELCVKDSLSVKCEASSELQLNGGVKSEDSDDSDSKNNIEQASSELIIKSEDSDDCLANYVKKKLLRKTKKAIESDDSDNSVRKHPAQKNKILHKLKSQTSYECKKCDLKFANFQLLKLHRQDKNHPRNGYGRKTCKICAKSVGYSRMNQHMRIHTREKPYCCDACGARFSIGSNLRRHKLSAHSNEKPYRCDQCGRGFTRLSLLKDHGRTHTGEKPYVCNYCGKSFAQASSLRTHLFVHAKRGETEASDISLHMHQCPDCERSFATKPLLRAHLLIHGEKRFLCSDCGRSFISMILLKSHSKVHTGLKPYTCSVCGKTFSHAGSLKSHSLIHTGEKPFACTVCNRSFTQRSHLKYHSRTHSGERPYVCSVCGKTFALNGNLTVHMRTHTGETPYLCPVCGKGFHDSSSMKKHKKGHGPQDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01041115;
90% Identity: iTF_01041115;
80% Identity: -