Nbre010933.1
Basic Information
- Insect
- Nebria brevicollis
- Gene Symbol
- -
- Assembly
- GCA_944739395.1
- Location
- CALYJC010000183.1:93479-95998[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.035 3.2 9.3 0.1 2 23 78 99 77 99 0.94 2 18 9.9e-05 0.0092 17.3 1.3 1 23 118 140 118 140 0.99 3 18 4e-05 0.0037 18.5 2.1 1 23 145 167 145 167 0.97 4 18 0.0001 0.0093 17.3 2.7 2 23 174 195 173 195 0.97 5 18 0.0038 0.35 12.3 1.1 1 23 201 223 201 223 0.95 6 18 0.00055 0.051 14.9 2.4 1 23 229 252 229 252 0.97 7 18 0.00025 0.023 16.0 2.7 2 23 264 285 264 285 0.97 8 18 2.3e-05 0.0022 19.3 1.8 3 23 293 313 292 313 0.99 9 18 0.00034 0.032 15.6 5.5 1 23 319 341 319 341 0.98 10 18 4.1e-07 3.8e-05 24.8 2.1 1 23 347 369 347 369 0.98 11 18 0.0098 0.91 11.0 0.1 1 21 375 395 375 396 0.94 12 18 0.031 2.9 9.4 2.2 1 13 455 467 455 482 0.95 13 18 0.00058 0.054 14.9 1.4 1 23 486 509 486 509 0.92 14 18 3e-06 0.00028 22.1 3.1 2 23 523 544 522 544 0.97 15 18 0.00011 0.01 17.1 0.8 1 23 550 572 550 572 0.96 16 18 9.5e-05 0.0088 17.3 4.6 1 23 578 600 578 600 0.98 17 18 0.00088 0.082 14.3 0.5 1 23 606 628 606 628 0.98 18 18 0.0099 0.92 11.0 2.1 1 23 634 659 634 660 0.96
Sequence Information
- Coding Sequence
- ATGGAACCGATGGTCCAGATAAAAACAGAACCACTCGACGAAGATGAAAGCTTACTAGATTTAGTGAAACGTCTATCGAAATTACGTCAAAATAAAACGATTAGCACAAAACGAGCACAACCGCGCAAAGCCAAATATGAGCACTACGAAAACCCATTCGTTTACAACAATATGGCAGCTAAGAAAAGTCCGattcaaaaagaaaaaccCGCGACAACAATTTCCAAATGGACGTGTTTGATCTGCAATAAAAATCTAACCGGCAAAAATGAATTGATCGAGCATTATTCCGCCCACAAAGACGACAAAATCAAATTGAAAAAAGGTGCCATCATCCCGGAGAATGAAGTGTACCAGTGTGATGTATGCTTGAAAGAGTTTACGTCAGAGAAACGTTTCGAAAAGCACATGGAAACGCATAATGATAGCCGCTTTAACTGTGATTATTGTCAGAAAAGCTTTAAAAAACCGTTTGATCTAGCAGTTCATAAACGGTTTCACTCAAATGACAACAAGCTCAAGTGTCATATTTGCGAGTACACAACCACGTACCCATCTACACTAAAAACACATTTACAACGTCACGACTCGGAATACAagtataaatgtgaaatttGCGGTAAAGGATTCTTTGTTTTTACTTGGTTTGAAGAACATAAGAATTTCCACTCCGGCGAAAAGCCGTTCAATTGCAATTATTGTGGGAAGAACTTTCTATATTCACGTTATTTAACCGCGCACAAACGCAGCATGCATCCTGAATGTTATACAGACGTGCCGCCGGTAAATGAGTGTTCGTTTTGCCAGAAGCGCTTCGCACACAAGAAGTCTTTGTTGCTTCACATTCGCGGGCATACCGGCGAGAATACTGTTCTTTGTGATATTTGCGGCAAACGTTTGTCGAGTAATGATCATTTGAAATTGCATCGACGCATTCATACCGGTTACAAGCCGTATTGTTGTAGCAGTTGTGGTAAAGGGTTTTCCAAGAAATGTAATTTGACGTTACATGAACGTGTACACAGCGGGGAGAAGCCGTATGTATGTGACGTTTGCGGCAAGTGTTTCTCGCAACGTTCCACATTGGTGATACATACACGGTACCATACCGGCGTGAAACCCTACGTGTGTCATTTGTGCAATAAAGGATTCGTGGCCAAAGGTGTTTTATCCGTTCATTTGAAGAATTGTAATGTTGACAAAACCGATATCGTAAATCGTATCACGAACATTAGAAATAAGCAGAAACGTGTGCTGAAACGACCAGCGCCTGAGCCGGAAGAACCACcacaaataaaagaacataAATGTTATACGATACGCGTCGTCGCCGCCGATGGTAAAGAAAAACACCAGTGCACATATTCGTGTGAAATTTGTGGTAAAATCTTCCGGAGCAAACGATGCTCGGCGAAAACGTGTAAACTAGTGTCGAAAGATCCGAACAATAAGTTTTATTTGTGCGAGATTTGCGGTAAAGTGTTCAATTTCATATCGTCGTTCATCGCACATCACAACTTTAAACATCGCGAATCGAAACTATTTCTCAAAGAGGCACGCCTTAGTGAATGCAACATTTGCCATAAACGGTTCAGTACCAAATGGAACATGAAAATACATATGCAAAGTCATCTGGATTATTATCCGTATCTCTGTGAGATTTGTGGgaaaaaatttaagaaatcggacatatttaaaatacatttacgaGTACATGCTGGCATTAAACCATATTCGTGTCAGACGTGTCAGAAATGTTTCGTGACTAAAGGAATGTTAACTACTCACAATCGAAGTCACACTGGTGAAAAGCCGTATTCTTGTGATTTTTGCGAGAAGAGCTACGCTGGAATGACAGCCTTGAGGCTCCATCGACGGATGCATACTGGCGAGCGCCCGTTCAAATGTCACGTATGCCCCAACGATAGAGGATTCATATCGAAAAAGGCCTTACGGATTCACTTGAAACAACCACATCATGATTag
- Protein Sequence
- MEPMVQIKTEPLDEDESLLDLVKRLSKLRQNKTISTKRAQPRKAKYEHYENPFVYNNMAAKKSPIQKEKPATTISKWTCLICNKNLTGKNELIEHYSAHKDDKIKLKKGAIIPENEVYQCDVCLKEFTSEKRFEKHMETHNDSRFNCDYCQKSFKKPFDLAVHKRFHSNDNKLKCHICEYTTTYPSTLKTHLQRHDSEYKYKCEICGKGFFVFTWFEEHKNFHSGEKPFNCNYCGKNFLYSRYLTAHKRSMHPECYTDVPPVNECSFCQKRFAHKKSLLLHIRGHTGENTVLCDICGKRLSSNDHLKLHRRIHTGYKPYCCSSCGKGFSKKCNLTLHERVHSGEKPYVCDVCGKCFSQRSTLVIHTRYHTGVKPYVCHLCNKGFVAKGVLSVHLKNCNVDKTDIVNRITNIRNKQKRVLKRPAPEPEEPPQIKEHKCYTIRVVAADGKEKHQCTYSCEICGKIFRSKRCSAKTCKLVSKDPNNKFYLCEICGKVFNFISSFIAHHNFKHRESKLFLKEARLSECNICHKRFSTKWNMKIHMQSHLDYYPYLCEICGKKFKKSDIFKIHLRVHAGIKPYSCQTCQKCFVTKGMLTTHNRSHTGEKPYSCDFCEKSYAGMTALRLHRRMHTGERPFKCHVCPNDRGFISKKALRIHLKQPHHD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -