Nbre002989.1
Basic Information
- Insect
- Nebria brevicollis
- Gene Symbol
- -
- Assembly
- GCA_944739395.1
- Location
- CALYJC010000028.1:81927-84243[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.011 1 10.8 0.6 2 23 181 204 180 204 0.90 2 17 3.4 3.2e+02 3.0 2.0 3 23 211 231 210 231 0.93 3 17 2.2e-07 2e-05 25.6 0.4 1 23 256 278 256 278 0.98 4 17 1.9e-06 0.00018 22.7 1.1 1 23 284 306 284 306 0.98 5 17 1.4e-05 0.0013 19.9 4.9 1 23 312 335 312 335 0.98 6 17 1 95 4.6 1.0 1 23 341 363 341 363 0.82 7 17 0.00013 0.012 17.0 4.1 1 23 370 392 370 392 0.99 8 17 7.2e-07 6.7e-05 24.0 0.4 1 23 398 420 398 420 0.98 9 17 6.5e-06 0.00061 21.0 0.9 1 23 426 448 426 448 0.98 10 17 1.8e-05 0.0016 19.6 0.3 1 23 456 480 456 480 0.93 11 17 1.4e-06 0.00013 23.1 1.0 1 23 486 509 486 509 0.98 12 17 1.1e-08 1e-06 29.8 1.5 1 23 515 537 515 537 0.99 13 17 0.0019 0.18 13.2 5.4 1 23 543 565 543 565 0.98 14 17 6.4e-06 0.00059 21.0 1.5 1 23 571 593 571 593 0.98 15 17 2.3e-08 2.1e-06 28.7 2.9 1 23 599 621 599 621 0.97 16 17 1.3e-06 0.00013 23.2 0.8 1 23 627 649 627 649 0.97 17 17 0.0018 0.16 13.4 6.5 1 23 655 677 655 677 0.98
Sequence Information
- Coding Sequence
- ATGAAATCCTTGCACGAAGAATATATAACAGAAATATTCGCCGTTGAAGCATTTATGTCAATCACATCGCTAAagaattatGATGCCCTACCAACATTAATTTGCAACGATTGTTTATGCGAATTGGCCCGCtcttacaaattcatttcacaaTGTCGAGAATCCGACGAGAAATTACGGAATCTTTTAAAAGCACAAGAAACCGATGTTGGCGATGACATAATAAACTTCCATTGTATTGATATTAAAGCAGAAGTCCAGGGCGATTTGGACTGTTCTGATGAGTTGGAGTTGGAAAACCATCAAGTACACTCAGAAAATGTGATTAAGATCGAATGTCGCACTATTAAACCAGTGAATAAACAAAATGCCACTGAACAATCGCTGCAATCATTACAACCGGATGAATTTCAAACTGATCGAAACCAAGAATTAGAATTGATAAAGCATGAATCAGAGCCTGTGATTAAAACGGAAATTGACGATaagattgaaataaatgatggTACGAGTAATGAAATCGAGTTGGAACATTCAGACCGATGTAAACAGTGCGGCATTAAATTTCCGACGTATATGTTACTGCTGTATCATTACCAAAGAATCAAACATACAAATTTGAAAGAGTTTTGCAGATTTTGTTCGTTAATTTACGATTCTCGCAGTTTGCACCGGCATGTGAGATTAGCACACAAAGATGTTGCAAATGAAACCAGTGACGCTTCTGAAACAGTGAACGCTAGTGACGCCAGCAACAAATGCACGTATGCGTGCAAAGTTTGCGGGCAAACTTTTACAGGGAATTCGAATCTAACAAATCATGCACGGACTCACACTGGCGAAAAACCATTCTCGTGTACTATATGTAATAAGTCGTTTGGTTTGAAAGATACTCTAATGACACATATTAGAACACACACGGGCGAAAAGCCATACTCGTGCTCTGAGTGTGAGAAATCATTTAATCATAGAATTAGTTTGAAACACCATATGATGATGACGCACACTGGGAAAAAACCATTCATATGCGAAATCTGTGGGAAACTATGTAATGAAAAGTCAATTTTAGATTTTCACATGCGTCTACATACGAATGAAAAAAAACCTTATTCGTGTACGATTTGTAGCAGTACGTTTCGCCTTAAACACAATTTAACAGTGCATACGCGTACTCATTCCGTTAATTTGCCGTATCCGTGTACAGTGTGTggatttacatttaatttaaaagcgAATTTAAAACGTCATATGCTAGTGCATACCGGTGAAAAGCCATTCTCGTGCAACATTTGCGACAAAGCGTTTCTACAAAAGATTAGTCTAACAAATCATATGCGTTCACACACCGTTGCAATAGAAAAAGCATATCCATGCACGATTTGCGATCTTACATTTAACAGCAAAATGAATTTAGCAGCACATACGCAAACAACACAACATATCGTAGATAAACCATATCCATGCACCATGATGTGCGACAAGTCATTCGAACACCAACGTAACTTAGAGGAACACATGATGGTGCATGCTGCAGAAAAGTCGTACCCGTGTTCAATTTGTGGAAGATCATTCCGTCAAAAGACTACATTAAACACTCACATGCGCACGCACACTGGCGAGCAACCGTATTCATGTACAATTTGccaaaaatcatttaaatttaaaccaaGTTTAACGTGCCATATGTTTACCCACACTGGGGAGAAGCCATTTTCTTGCACCTATTGTGATTATAAAGTCAGCGataaaacgaatttaaatcgTCATTTGTTGATGCATACAGGGGAGAGGCCGCATCCGTGCACACTTTGCGATAAGTCGTTTAGTCAGAAGTCTAGTTTACGAATTCACATGCGAACGCATACGGGCGAGAGGCCTTATTCATGTTCAATGTGCGAGTTTTCTTTTGTGCAAAGATCAAACTTAACCAGACACATGGAAGCACATACTAGTGATAAACCGTATTCATGtaaaatatgtggatgttcgTATAACCGAAAGAAAGATTTAACGTGCCACGTCCGGACTCATAATGAGAACAAATACTAA
- Protein Sequence
- MKSLHEEYITEIFAVEAFMSITSLKNYDALPTLICNDCLCELARSYKFISQCRESDEKLRNLLKAQETDVGDDIINFHCIDIKAEVQGDLDCSDELELENHQVHSENVIKIECRTIKPVNKQNATEQSLQSLQPDEFQTDRNQELELIKHESEPVIKTEIDDKIEINDGTSNEIELEHSDRCKQCGIKFPTYMLLLYHYQRIKHTNLKEFCRFCSLIYDSRSLHRHVRLAHKDVANETSDASETVNASDASNKCTYACKVCGQTFTGNSNLTNHARTHTGEKPFSCTICNKSFGLKDTLMTHIRTHTGEKPYSCSECEKSFNHRISLKHHMMMTHTGKKPFICEICGKLCNEKSILDFHMRLHTNEKKPYSCTICSSTFRLKHNLTVHTRTHSVNLPYPCTVCGFTFNLKANLKRHMLVHTGEKPFSCNICDKAFLQKISLTNHMRSHTVAIEKAYPCTICDLTFNSKMNLAAHTQTTQHIVDKPYPCTMMCDKSFEHQRNLEEHMMVHAAEKSYPCSICGRSFRQKTTLNTHMRTHTGEQPYSCTICQKSFKFKPSLTCHMFTHTGEKPFSCTYCDYKVSDKTNLNRHLLMHTGERPHPCTLCDKSFSQKSSLRIHMRTHTGERPYSCSMCEFSFVQRSNLTRHMEAHTSDKPYSCKICGCSYNRKKDLTCHVRTHNENKY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01041086;
- 90% Identity
- iTF_01041086;
- 80% Identity
- -