Basic Information

Insect: Nasonovia ribisnigri
Gene Symbol: Bcl11a
Assembly: GCA_027563275.1
Location: JANEHQ010001815.1:13975-14832[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00062 0.074 14.4 0.6 2 23 81 102 80 102 0.97

2 7 8.8e-06 0.001 20.2 0.7 1 23 108 130 108 130 0.97

3 7 0.00077 0.091 14.1 0.1 1 23 137 159 137 159 0.95

4 7 2.1e-06 0.00024 22.2 3.7 1 23 170 192 170 192 0.96

5 7 2.8e-06 0.00033 21.8 2.1 1 23 198 220 198 220 0.98

6 7 1.2e-05 0.0015 19.7 0.9 1 23 232 254 232 254 0.98

7 7 1.9e-06 0.00022 22.3 0.4 1 23 262 284 262 284 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00062	0.074	14.4	0.6	2	23	81	102	80	102	0.97
2	7	8.8e-06	0.001	20.2	0.7	1	23	108	130	108	130	0.97
3	7	0.00077	0.091	14.1	0.1	1	23	137	159	137	159	0.95
4	7	2.1e-06	0.00024	22.2	3.7	1	23	170	192	170	192	0.96
5	7	2.8e-06	0.00033	21.8	2.1	1	23	198	220	198	220	0.98
6	7	1.2e-05	0.0015	19.7	0.9	1	23	232	254	232	254	0.98
7	7	1.9e-06	0.00022	22.3	0.4	1	23	262	284	262	284	0.98

Sequence Information

Coding Sequence: ATGATGGGCGATGTGACTGCTGAAAGTCCTCCTGCTGATGATTTAAATAACTCAGGTTCTTCTTCTTCTTCATCATCCGATTCTGATGGCGAATCAAGTAGTTCATGTACCAGTTCTAGTTCTTCTTCCTGCTCTGAAACACCTAAAAACCAGTGCAATGACTCTAGTTTTCCAAATTGTGATGAAGAAACCCCAGAAGATACAGATACTCCGCAGTCAAATGGCCAATCTGAATGGATGGTTTGTCAGCTTTGCCTGTACAAAGTGAAAACACCTTTACAATTAAAACAACACATGCGAATGCACACTGAACATAAAGTACATCGTTGTGCCATATGTAATAAAACATTTGAACAAGCCACTCGACTAGAAAAACATATTGCCATACACTGTGGCACAGATAATCGTTTTGAATGTTCACTTTGTGGCAAAGTATATAAACTTCGAACTCAAATCGTCAGCCACATAGCAGCTCACAAAAAACAAAATTCTGGACGTCGTATATCATATACATGTCACATTTGCACAAAAAAATTTTCTAATAAATCAAAACTGAAGGAACATGTATCAGGACATGAAAACGGGACACTGCATTCATGTGATGTTTGTGGGCGAACTTTTAAATTAAATTCATATCTTGTTGTCCACAAAAGAACGCATGAGATGAATGTGTCTTATACGGGGGATAAACCATTTACCTGTTCACTGTGTAACAAGTCATTTTTGAGTAAAAGTAACCTAGATCTACACATGTTGGTACACAATTACGTTAAAAAAGCATCGTATAGCTGTGACATATGTGGAAAAATATTTATGCGCAAATATAACTATGATGCTCATGTGAAAATACATGAATAG
Protein Sequence: MMGDVTAESPPADDLNNSGSSSSSSSDSDGESSSSCTSSSSSSCSETPKNQCNDSSFPNCDEETPEDTDTPQSNGQSEWMVCQLCLYKVKTPLQLKQHMRMHTEHKVHRCAICNKTFEQATRLEKHIAIHCGTDNRFECSLCGKVYKLRTQIVSHIAAHKKQNSGRRISYTCHICTKKFSNKSKLKEHVSGHENGTLHSCDVCGRTFKLNSYLVVHKRTHEMNVSYTGDKPFTCSLCNKSFLSKSNLDLHMLVHNYVKKASYSCDICGKIFMRKYNYDAHVKIHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00340829;
90% Identity: iTF_01350314;
80% Identity: -