Basic Information

Insect: Napeogenes inachia
Gene Symbol: topi
Assembly: GCA_959347355.1
Location: OY365803.1:14368376-14373513[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0067 0.71 11.3 3.1 2 21 165 184 164 185 0.93

2 25 0.64 68 5.1 2.8 1 23 218 241 218 241 0.96

3 25 0.0016 0.17 13.3 0.5 2 23 247 268 246 268 0.94

4 25 0.11 11 7.5 2.8 3 21 273 291 271 292 0.93

5 25 0.0017 0.18 13.2 0.4 2 23 336 358 335 358 0.95

6 25 0.0034 0.36 12.2 1.1 1 23 391 413 391 413 0.98

7 25 0.0012 0.12 13.7 0.4 1 23 419 442 419 442 0.97

8 25 0.19 20 6.7 0.3 3 23 453 474 453 474 0.93

9 25 0.017 1.8 10.0 5.2 1 23 485 507 485 507 0.98

10 25 2.5e-05 0.0027 18.9 0.3 2 21 631 650 630 651 0.95

11 25 0.064 6.8 8.2 1.2 3 23 657 677 656 678 0.95

12 25 0.012 1.3 10.5 0.7 2 23 711 732 710 732 0.96

13 25 5.6 6e+02 2.1 3.1 1 20 735 754 735 756 0.91

14 25 0.00088 0.093 14.1 1.4 1 23 768 791 768 791 0.93

15 25 0.00021 0.023 16.0 3.5 1 23 797 819 797 819 0.97

16 25 3.8 4e+02 2.7 0.3 1 23 853 876 853 876 0.87

17 25 2.2e-05 0.0023 19.1 1.8 2 21 1000 1019 999 1020 0.94

18 25 1.2 1.3e+02 4.2 0.0 3 23 1027 1048 1026 1048 0.94

19 25 0.0003 0.032 15.5 2.7 2 23 1082 1103 1081 1103 0.97

20 25 1.6 1.7e+02 3.8 1.5 2 21 1107 1126 1107 1127 0.91

21 25 1.5e-05 0.0016 19.6 1.5 1 23 1153 1176 1153 1176 0.96

22 25 0.00048 0.051 14.9 0.5 1 23 1182 1204 1182 1204 0.95

23 25 0.32 34 6.0 0.2 1 23 1210 1232 1210 1232 0.97

24 25 0.0049 0.52 11.7 0.7 1 23 1238 1261 1238 1261 0.94

25 25 0.00079 0.084 14.2 4.9 2 23 1268 1290 1267 1290 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0067	0.71	11.3	3.1	2	21	165	184	164	185	0.93
2	25	0.64	68	5.1	2.8	1	23	218	241	218	241	0.96
3	25	0.0016	0.17	13.3	0.5	2	23	247	268	246	268	0.94
4	25	0.11	11	7.5	2.8	3	21	273	291	271	292	0.93
5	25	0.0017	0.18	13.2	0.4	2	23	336	358	335	358	0.95
6	25	0.0034	0.36	12.2	1.1	1	23	391	413	391	413	0.98
7	25	0.0012	0.12	13.7	0.4	1	23	419	442	419	442	0.97
8	25	0.19	20	6.7	0.3	3	23	453	474	453	474	0.93
9	25	0.017	1.8	10.0	5.2	1	23	485	507	485	507	0.98
10	25	2.5e-05	0.0027	18.9	0.3	2	21	631	650	630	651	0.95
11	25	0.064	6.8	8.2	1.2	3	23	657	677	656	678	0.95
12	25	0.012	1.3	10.5	0.7	2	23	711	732	710	732	0.96
13	25	5.6	6e+02	2.1	3.1	1	20	735	754	735	756	0.91
14	25	0.00088	0.093	14.1	1.4	1	23	768	791	768	791	0.93
15	25	0.00021	0.023	16.0	3.5	1	23	797	819	797	819	0.97
16	25	3.8	4e+02	2.7	0.3	1	23	853	876	853	876	0.87
17	25	2.2e-05	0.0023	19.1	1.8	2	21	1000	1019	999	1020	0.94
18	25	1.2	1.3e+02	4.2	0.0	3	23	1027	1048	1026	1048	0.94
19	25	0.0003	0.032	15.5	2.7	2	23	1082	1103	1081	1103	0.97
20	25	1.6	1.7e+02	3.8	1.5	2	21	1107	1126	1107	1127	0.91
21	25	1.5e-05	0.0016	19.6	1.5	1	23	1153	1176	1153	1176	0.96
22	25	0.00048	0.051	14.9	0.5	1	23	1182	1204	1182	1204	0.95
23	25	0.32	34	6.0	0.2	1	23	1210	1232	1210	1232	0.97
24	25	0.0049	0.52	11.7	0.7	1	23	1238	1261	1238	1261	0.94
25	25	0.00079	0.084	14.2	4.9	2	23	1268	1290	1267	1290	0.95

Sequence Information

Coding Sequence: ATGAGCAAACAAGTGGACGTTAAAGCGTTAGTATCTCACATAGTTCGTGGGGACGGTGTTCAAAAATGCCGAATCTGTATGGGAGACACCTCCGAAGGACAGGTCCATTTAGGGGATACTGTGATGATGGATGGAGAAAAACCTGTTACGCTTTCAGAACTGCTAGAAACAGTCACTGGAGTCCAGGTGCTGTTTGAAAAGGATCTGCCTACCGGAGTGTGCCCGGCCTGCCTTATGTGTGCTCTAAATGCTGCAGAATTCCGTTCACAATGTCAGCAGGCTGCTAGCCAATGGGATTTGACTATTGAACTTTTAAATGGTTTATCATCACAATATCTTAGTACAGAAAAAACAATCTTAGCTCTATTGGAAAAAAGTCAGATGATCATTATTAAGGATGAAAGTTCCTTTAAAATAGGAAATGCAGCAAATAGATTCAATGACTACTTGTCCAAACCTAAGGAGGTGAAGAATGAATGTCCAATATCTTGTGTATGCCCAAATTGTGGGAAACAATTTCAATTTGCTCATCAGTTGAGCCATCATTTAAAAGAATCCACAGACTTACAGCGGGCTTGTTATATTTGTGCTGATATTATGGCTCGGAATGAGTTAATAGATCACATGGCTGAAGTGCACAACAAAGAGTCTTATGATTGTAAAAAATGTCCAGCCATATTGTGTTCCTATAACCAGTTCAAGATGCATTTGTCAAAGTCGCATGCACATGCAGCTTGCACATGTGTGGAATGTGGACGCAGTTTTCAAACCCCAAACGCGTTTTATGCTCACGTATCGGTACACAAATCTCAAAATTGCCCTAGTTGTGATAAATTGTTTCGTAACCAAACTTGTTACATTCACCATGTGAAGAGTTGTTGCAATTTAGACAAAAACAGAGAGGATACGTTCCGTACGAAGTCAAAAGTGACCGTGGAGGTTAAAAACGCAATTAGTAAACGAAAAATTAAAGTTGGTCTGCGAGGGAGCGCGAACAAAGAATGTATTTGTGACTATTGTGGTAAAAAGTTTGCGGGGAAGAAATTCGTGGCAGCTCACATCCAGATTGTTCACATGAAAAACACTCATCGCCCTTGCGTGTATTGTGGGAAGTTATTGGCTGCGGCTCACATGTCTGAACATGTTAAGAAGCATGAAATCGATCGCTCATACAGTTGCGAACACTGCGGCGTTGTACTCAAAACTCGATTAGGTTATACCCAACATTTAAGACTGCATACTGGTGAAAGACCATACGCGTGTAAAATTTGTGGCCAGACGTTTTCGGCGTCTTCTAGACGCTCGGAACACATACGTAAAGCCCACAAGAATATTGAGGTTGTATTAAAACATGGGTGTAGATTTTGTCCAGCCAGATTTCGTCTTCCATATCGTTTAAAGAAGCACTTGATTGCAGTACACAATGACGAAAACGAAAAAATTTCATTGGATTTTGAATGTAAGGAATGCAACGAGAAGTTTGGTTCCTGTCGTGGACTTCTGCATCACAGCCGCAAACATCAGAATATTCCCTTCCCACCGAAGAAACCTGAAAAATCCGTTATGTTCAAAGTGCTGGAGGAAACGGAACTGCCACCAGGGCTGTGCTGCAATTGTTCGAATACTGCTCTCCTGGTGTGGCAGTTCAGGCACCTTTGCCAGCAATCCGAGCACCAATGGAAACGAACTATCGACTTGCTAAACCACCCTGATGTAATGACTCCACTGGATtgcaaaactttttatatatgctGTGCAGAAGAAACTATTTACAAGGACAATACTGGAGTTAGAAGCCTAACCGCAGCTGCTGCGAGATTTAATTTTGTCGTAAAAAGAAAAGCCATACGACCAAAGTATAAAAAACATGCAAAAATCAAAGGTGAATCTAAATGTAGTGACTGCGGAAAGAAATTCGCACTTCCATATTACTTAAATAGGCATTTGAGAAATACATTAAAACGCGCGTGTACAGAGTGTGGCAAAACAATGCAGAAAGATAAATTGGCTCGACATTTGGAAAAGGTTCATCACAAATTAGTTCATCACTGTGATATTTGTCACAAGTTGTTTGATGAACCGTGTCATTTGGGTCGACATAAAGACTTATTTCATAGCAATGAATCATTGGAGTGTCATGTCTGTAGGAATGGTTTTACTAGCGACAGATCGTTAGCCGCTCACATGTACTCCCACACCTTGTTCAACTGCTCCTCGTGCAACACTGGCTTTGAAAACcgcaaatgttatatatatcacAAAGAACGATGTACaggaaaaaaaattaacactgaAAATATATACGAATGTCATGACTGTGGcagtaaatatacaaaaaagccGTCGCTACGAATCCATATTGTGCAAAAACATTTGAATGTATTGCCATTCGTTTGTCAGATATGCGGCAAGCGCTGTTCAACCAGGAACCACTTGTCATCCCACGAGCTGGTACACAAACCCGAAAGAAAAGTGTATGAATGTTTTTGTGGTGCTAAAATGCGATCTGCCCTTGGATTTGAAATGCATCAAAGAATACATTCAGGGGAGAAGCCCTATGTATGTGAAGTTTGTGGAGACAGATTTCTATCTGCTTCTAGAAGGTTAGATCACATAAAACGTAAACATAGAAGCAAGGAACTGGCCCATGGTTGCGACCGGTGTGACGCTAAATTTTTACATGAAGAGCTATCTATACCGAAAGGGCTTTGCATATCCTGTTCAAGTACAGCTATAACAGCTTACGAATTCCGTACGTTTACAAGAAATTCAGCTAATTTATGGATCAATTGCATCAACACTTTAGAGTCTCTGCCAAAATTGAATACGCATAAATCTATATACGCTATAATAAGGGAAAATATGACGCTGCAAACAGTGAATACTTTCGACGGGAAGAGAGCAGACCTTGTTGAACACCTTTCCAATCGATTGATGAAGAAAAAACCAGTGATTGTTGAAAGGAAACCGAGGCATCCGAGAACAGGGCCGGCTTGCAGCTGCAAGGACTGTGGCAAATCATTTTCAAGTCCATATTTCCTGAATTTACACTTAAGAAATAGTGGTCAAAAGGAGGCGTGTTGGTTATGTGGAGCCGTGGTTGGAAGAGGTCGACATTTGAGAGAACATTTGGCAATAGTACATAAAACTGATATGTTCCTTTGTCCAGACTGCCCCAATCTCTTTAAATGTGAACAGGATCGCAAGAGACATCTCAAAAAATATCACGGTCCAGGAAATCTGACTTGTTCTGATTGTGGAAGGACTTTCCAAAGACATACGTCGTTTGAGGTTCACACCCAAATGCACGCAGTGAGAACGTGTCGCGCGTGTGGGGCTCAGTTCACAAACCGTGGATGTTACAGGGAACACAGGTCAAAATGTGAACCCGACGCAAAGCCGGATAGAAAAACAGTTCCTCGAAGCCGTCGATCTAACGTTCGAGACCCGGCCACGTTTACATGTGATTATTGCGGAAAGACTTACCATTCTCGACCTCAACTAAAAAACCACATAATGTGGATTCACATGGATGTCAGACCACATCAATGCCAATGGTGTGGAAAGCGATTTTACACTCCAGCTCGTTTGGCAGAACACACAGTTGTACATACCCGCGTAAGAAATTTCGAATGTGATATTTGTAACGCCAAATTGGTATCCAAAATGGCCGCAGTGTATCACAGGCGACGTCACACAGGAGAACGTCCTTATGAATGTCAGGACTGTGGTGAAAGATTTATCTCGTCCTCCCGAAGGTCAGAGCACGCTAAACGTAGACACAACAAGGGTTTACGACTCCAGTGTCTTCATTGTCATGCAACTTTTGTTAGAAATCACGAACTTAAAAAGCATATAGATAAAGTTCACAATTCAGAAAACAATGATATTGTAGTTAAGGTAAAAAAAGTGAAGGAATATCCAGGTTCAAGAGattga
Protein Sequence: MSKQVDVKALVSHIVRGDGVQKCRICMGDTSEGQVHLGDTVMMDGEKPVTLSELLETVTGVQVLFEKDLPTGVCPACLMCALNAAEFRSQCQQAASQWDLTIELLNGLSSQYLSTEKTILALLEKSQMIIIKDESSFKIGNAANRFNDYLSKPKEVKNECPISCVCPNCGKQFQFAHQLSHHLKESTDLQRACYICADIMARNELIDHMAEVHNKESYDCKKCPAILCSYNQFKMHLSKSHAHAACTCVECGRSFQTPNAFYAHVSVHKSQNCPSCDKLFRNQTCYIHHVKSCCNLDKNREDTFRTKSKVTVEVKNAISKRKIKVGLRGSANKECICDYCGKKFAGKKFVAAHIQIVHMKNTHRPCVYCGKLLAAAHMSEHVKKHEIDRSYSCEHCGVVLKTRLGYTQHLRLHTGERPYACKICGQTFSASSRRSEHIRKAHKNIEVVLKHGCRFCPARFRLPYRLKKHLIAVHNDENEKISLDFECKECNEKFGSCRGLLHHSRKHQNIPFPPKKPEKSVMFKVLEETELPPGLCCNCSNTALLVWQFRHLCQQSEHQWKRTIDLLNHPDVMTPLDCKTFYICCAEETIYKDNTGVRSLTAAAARFNFVVKRKAIRPKYKKHAKIKGESKCSDCGKKFALPYYLNRHLRNTLKRACTECGKTMQKDKLARHLEKVHHKLVHHCDICHKLFDEPCHLGRHKDLFHSNESLECHVCRNGFTSDRSLAAHMYSHTLFNCSSCNTGFENRKCYIYHKERCTGKKINTENIYECHDCGSKYTKKPSLRIHIVQKHLNVLPFVCQICGKRCSTRNHLSSHELVHKPERKVYECFCGAKMRSALGFEMHQRIHSGEKPYVCEVCGDRFLSASRRLDHIKRKHRSKELAHGCDRCDAKFLHEELSIPKGLCISCSSTAITAYEFRTFTRNSANLWINCINTLESLPKLNTHKSIYAIIRENMTLQTVNTFDGKRADLVEHLSNRLMKKKPVIVERKPRHPRTGPACSCKDCGKSFSSPYFLNLHLRNSGQKEACWLCGAVVGRGRHLREHLAIVHKTDMFLCPDCPNLFKCEQDRKRHLKKYHGPGNLTCSDCGRTFQRHTSFEVHTQMHAVRTCRACGAQFTNRGCYREHRSKCEPDAKPDRKTVPRSRRSNVRDPATFTCDYCGKTYHSRPQLKNHIMWIHMDVRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICNAKLVSKMAAVYHRRRHTGERPYECQDCGERFISSSRRSEHAKRRHNKGLRLQCLHCHATFVRNHELKKHIDKVHNSENNDIVVKVKKVKEYPGSRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00461757;
90% Identity: iTF_00960328;
80% Identity: -