Basic Information

Insect: Myzus cerasi
Gene Symbol: zfh1
Assembly: None
Location: Mc3792:346-8964[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.18 24 6.3 0.2 2 20 27 44 26 45 0.93

2 7 0.02 2.7 9.3 0.1 3 23 72 92 70 92 0.94

3 7 1e-05 0.0014 19.6 0.6 2 23 99 120 98 120 0.97

4 7 7.1e-07 9.5e-05 23.3 4.6 1 23 129 151 129 151 0.99

5 7 3.2e-05 0.0043 18.1 1.5 1 21 157 177 157 178 0.95

6 7 0.00014 0.019 16.0 9.2 1 23 834 856 834 856 0.98

7 7 0.0093 1.2 10.3 4.4 1 21 862 882 862 883 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.18	24	6.3	0.2	2	20	27	44	26	45	0.93
2	7	0.02	2.7	9.3	0.1	3	23	72	92	70	92	0.94
3	7	1e-05	0.0014	19.6	0.6	2	23	99	120	98	120	0.97
4	7	7.1e-07	9.5e-05	23.3	4.6	1	23	129	151	129	151	0.99
5	7	3.2e-05	0.0043	18.1	1.5	1	21	157	177	157	178	0.95
6	7	0.00014	0.019	16.0	9.2	1	23	834	856	834	856	0.98
7	7	0.0093	1.2	10.3	4.4	1	21	862	882	862	883	0.96

Sequence Information

Coding Sequence: ATGAGTCTGGAGGGTCTTCTCAAGGATTACCAGGACCTGCACCACCAGCAGCAACAGCAACAGCAGCAGCATTTACAGTACTGCCCGTTTTGTCGGGAATCGTTTGACTTGGGATCGCTAAAGGAACACTTGGACGGCGGATGCCGAGCCCGGCCGCCTTCGTCGCAACCGTCGCCGCCCCCGACCACGGTTGCGGTCGCCGGCCAATACGGGTGTTTGCAGTGCAACGCCGCTTTTGGCAATCGCGACCTGCTCGAGAAACACGAACTGCTCCACTCGCCCAACGCCCAAGTGTCCTGCAAGGTGTGCAACAAGACGTTCGCCAACGTTTACCGTCTCCAAAGGCACATGATAAGCCACGACGAGAGCGCTGTGCTGCGCAAGTTCAAATGTCCCGAGTGCGAAAAGGCGTTCAAGTTCAAACATCATCTCAAGGAACACATTCGCATTCATAGTGGAGAAAAGCCGTTCGAGTGCTCCAACTGTGGCAAACGTTTCTCGCATTCCGGTTCATATTCTAGTCACATGACTTCCAAGAAGTGTCTGATCATTAATCTAAAAATGGGAGGCCGTGGGTCGCAGGCCAACAACCGGAACGCCGCTCACCATCAACCGAACAACGGTTTTCCGGGAAAGCGTCCAGTTCCTAATAACAACAACAACATAACCAACAACAACAGCAGCAACCACAACAACAACAGTATCGGTGCCGGTGGCAATGCGTTCTCGCCTCTGCTGCCGTCGTCGGTGTCAAAGTACGACTTGCAAGTGGCGCAGCCGAGTCCAGCACAGGCGCAATCGCTTACACAACAATCGTTCTATCACTCGCAGCCGAAAGCCAGCGCGGCAGCCATCTACTTCCCAGGACTGTTCAACACTCAGAGCAAGTTCAACATACACGATCTGCTGCAGCCGTCGTTGCAGATGCAGTCAGCGATGGCCAAGCAAGAACAAGAACAGCAACAACAACAGCAGCAGCAGCAGCAGAAGCAAGAACAAGATCAAGACGACTGCTGTAGTGGCGACGATGGAAAGAACAAGACGACAGATGAAGAAAACCGCAATAAAGAGCACGAGAGTGGTGGTGACGATTTCAACGACGAGGACGAAGAGGACGACGACGACGACAAATACGACAACGTGATCGACGTGGTGAGCGTTGTGAAGAAGGAACGCGAAAACGGCGGTGGAGGTGCGGACGAGGACGCGGTCGGCGAAACGGACGAGGCGGTCAAGAAACTCTTGGAGACGGTCAACGTATCTGCGGTCACCAAGCAGCTAATGATGGCCAACGCCGCGGCCGCCGCAGCCGCTGCCCTACACCACCAGCAGCCGCTGTCTTGTGGATCGTCGGGCGGTTGCCCCAGCGTGACTAGCGACTCGCCGCCGTACCACCACGGCTACAGCCTGTATCCCAATCACAATCACCATCACCACAACCTCCTCAACCACCACAGAGCCGAAAGTCTGGTTGGCAAAGCGACGGATTATTCCGCGACCGCCGGTTCCAAGACGACCATTAACAACAACAACATAAACAACGGTTATGACGGGGGCAGCGACTGTTATACCGACGACGAGCACAGACCGTGCACCACCGAAGAAGAAGACTCGGTGGACCAGGACGGCCGCAAGATCCGCGTCCGATCGCAGATAGCCGACGACCAGCTGGCTGTGCTCAAGGAGTGCTACGCCGCCAACCCGCGGCCAAAGCGCGAGGAACTGAGTCGGATCGCCGATCGGATCGGCTTTAACGTGCGCGTCGTCCAGGTTTGGTTCCAGAACAACAGGGCTCGGGACCGGCGCGAGGGCCGCCTGGTGCACATGCCGTACTCGCCCGCGTCCGCCGCTGCCCACGCTTTGGCCGCCCCGAGTCTCGCCGAGCAGCCGCTCGACCTGTCCACTAAGCGGAGCCGCCACGGCAAAGACGGCAGCGCCGATGACGACGAGTGCAACGGAAGCCGCGGTGTTACGCTAAACAACAAGTGCACCATTCAGTTCAAGTGTTGGACGGCCAACAACCGGGACGACTGCAGTTCGTCGCCGCCCGCGTCCATGCTGCAGCCGCAATGCCGCAAGACGTTCCTGGGAGGCGCGTACCCGCCGCCGTCGCCAGTTTGCGCAGCGCCACCACCGCCGCCGCCTTCATCACACCTGCACCATCCCGCGTCCCATTCGCCCATACCGGCTGTCGCGCTCCGGCACAACGGCAGCTTGAGCCCTGCGTCCGAGAAACGTTCGTGGAAGAGAGAATACGGAGACTGGAGCGACATGACGGACGAGGCCGAAGACTCGGGATGCACGTCCCAAGACCCTGACGACGCGGTATCCACCAGAGGCGGTGCAGGCGTCATGCACAACAACAATAACAACAACAACAACAACAACAGCCACAACAACAACACCAGTAACGGCGCAATGGCGGCCGCAGTCGGTTCGCCCAGCAAAAAATCCAAACCGTCATCAGTGGAATCTGCTGAAGTACCAGATCAAAGACCTCACAAGTGCGACGTTTGCCCGAAAGCGTTCAAACACAAACACCATCTGACCGAGCACAAGAGACTGCACAGCGGCGAAAAGCCGTTTCAGTGTTCCAAGTGCATGAAACGGTTCTCTCATTCGGGTTCGTACAGCCAGCACATGAACCACCGTTTCTCGTACTGCAAACCGTACAGAGAGTAA
Protein Sequence: MSLEGLLKDYQDLHHQQQQQQQQHLQYCPFCRESFDLGSLKEHLDGGCRARPPSSQPSPPPTTVAVAGQYGCLQCNAAFGNRDLLEKHELLHSPNAQVSCKVCNKTFANVYRLQRHMISHDESAVLRKFKCPECEKAFKFKHHLKEHIRIHSGEKPFECSNCGKRFSHSGSYSSHMTSKKCLIINLKMGGRGSQANNRNAAHHQPNNGFPGKRPVPNNNNNITNNNSSNHNNNSIGAGGNAFSPLLPSSVSKYDLQVAQPSPAQAQSLTQQSFYHSQPKASAAAIYFPGLFNTQSKFNIHDLLQPSLQMQSAMAKQEQEQQQQQQQQQQKQEQDQDDCCSGDDGKNKTTDEENRNKEHESGGDDFNDEDEEDDDDDKYDNVIDVVSVVKKERENGGGGADEDAVGETDEAVKKLLETVNVSAVTKQLMMANAAAAAAAALHHQQPLSCGSSGGCPSVTSDSPPYHHGYSLYPNHNHHHHNLLNHHRAESLVGKATDYSATAGSKTTINNNNINNGYDGGSDCYTDDEHRPCTTEEEDSVDQDGRKIRVRSQIADDQLAVLKECYAANPRPKREELSRIADRIGFNVRVVQVWFQNNRARDRREGRLVHMPYSPASAAAHALAAPSLAEQPLDLSTKRSRHGKDGSADDDECNGSRGVTLNNKCTIQFKCWTANNRDDCSSSPPASMLQPQCRKTFLGGAYPPPSPVCAAPPPPPPSSHLHHPASHSPIPAVALRHNGSLSPASEKRSWKREYGDWSDMTDEAEDSGCTSQDPDDAVSTRGGAGVMHNNNNNNNNNNSHNNNTSNGAMAAAVGSPSKKSKPSSVESAEVPDQRPHKCDVCPKAFKHKHHLTEHKRLHSGEKPFQCSKCMKRFSHSGSYSQHMNHRFSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00018912;
90% Identity: iTF_01031839;
80% Identity: iTF_01031839;