Mlal008946.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mythimna lalbum
Gene Symbol
ZNF219
Assembly
GCA_949319445.1
Location
OX439350.1:23320087-23334445[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 7 6.8e+02 2.1 1.8 1 23 265 288 265 288 0.85
2 8 0.0017 0.17 13.4 3.0 1 23 393 416 393 416 0.96
3 8 0.00096 0.093 14.2 3.3 1 23 562 584 562 584 0.98
4 8 0.00014 0.013 16.9 0.7 1 23 589 611 589 611 0.97
5 8 5.5e-06 0.00054 21.2 0.5 1 23 617 640 617 640 0.93
6 8 4.4e-07 4.3e-05 24.7 1.4 1 23 646 668 646 668 0.99
7 8 1.5e-05 0.0015 19.9 3.3 1 23 674 696 674 696 0.99
8 8 1.8e-06 0.00018 22.8 2.3 1 23 702 724 702 724 0.98

Sequence Information

Coding Sequence
ATGGACGAAGCCGTCACGCACTATATAACTTCCCACCCAGCTGATCAGGCCGTTCATGTAGATGGCAATGCCTTGGCCCTCAATGTACAGGATGATGGAGGCAGCAGAGTGGCAATCATGCACTCTCAGACTTACTCTACGTCAATGTGCAGGCAAGTGTCAGTGGGTGACCATGTGGTTGAGGGACAGTGGAATGACGAGATCATGGATGAAGGCAGGCTGGCCGCCTTCATGGCACACATCACAGCACAGCAGTCCAGAGGGCAACAACTGCACCATAAGGTGCACACAGTGAGGGGTGATGTGGACTCATCTATTATCCTTGATGGTTCCATGAGACTGTTCCATGGCCAGTCTATGGACCAGTCACAAGAACCGATAGTGGTGGAGGTGCCCCCGTTGCCGCCACTGCCTCCTCTGCAGGAGATGAAGAGGTGTCAGGACAACGATTGGTTCAATAACAAGGCTAAACCATCACTCAAAGATGATTCGTCCATGATAGATTCAGACGGTCCTGTGTTGGAACTGGGCGCGGGGGCGTCGCCGGGGCAGCACAAACTGCAGAGCAAGAAGAGTCTTCCACACAAGAAGAGGATATCCAGGAAGCTGAAGAAGAATAATGGGAACAGCACTCCTCAGCAGgacatagtggtgatcagCTGCACGGACGTGGAGGGTCGCATCAGCTGCGCGGACCACGGCCAGGAGCAGGAGATCCTGCCCGACAACTTCGTGCAGCAGGAGCACTTGCCTGACGAGACACACCATATCACGCACGAGGTCCGCCCGATCTTCATCTGCCAGCTGTGCGGTGAGTTCTACGGCGACGAGCAGCTCAAGTTCTACCACCACCTCAAGCAGCACTACGAGCCGCACATCATCATCGAGAACCCCGTGCAGGACCTGGGCATCGATAAGATGACCAACTCATGCATCGTAGATAACGTAACAACAATCCCAGACTCGATAGTAGAACTGTCTCTAGAGAATTCCATACCAAAAACTATATACCAATCTATGGACAAAAACGTCTTATACACGACAAGCGACAAAACGTTTACCTATACCAACAATAAGGTTCAATATTCTATGGCAAGTATGGACAAGGAACCACCAACGGTAGTTCAGGAGGTCGAGAAGACAGATTTGTATGATACGTTGGATAAACTGGACTTATATAGCTGTGGGAAGTGTAACAAGTCGTTTAGGAAGCAGAAACAATGTGAAGCGCATATCAAGGAGGCGCATTCTAATATgaagTTAGAAGACATGGGTGAGTTCAGCGAACCCGAGGACCTGATGGAGGGCATCCATGTGGCCGTGGACGAGCCTCCGGAGCACTACGACCACGCGCTACTGCCGCACCTCACCGTGGAGAACGGGCACGCTCACCAGGACAACGGGCGCCAGTGGTACGGGCGCCACGCGAGCGGCGCCCCGAGCGCGGGCGGCGGCCTGGGCGCGGCGTGCTGCGCCGTGTGTGCCGCAGCGCCGCACGACTCGCATCACCTCAAGCTGCTCAAAGACGAAGTCCTGCGCCGGATCTTAGAGACAGACGTAGTGACGACGGACAGCCAGAACTTCACCGACAGCACGATGACCGACACGGCCGACACGACCGACCTGCCGCCTGACGAGCCGCCCGCTGATGAGAAGACGGATGACAAGAAGAAACAGAAGAAGTTTGAGTGCCAGCAGTGCCAGCGAGTGTTTCAACATAGGAACAGTTTGCTGTACCACATGCTGTCGCACAGCAGCAAGCAGCACATGTGTCGCGAGTGCGGGAAGGGGTTCTACACAGTCGCTGCACTTAAGATACACAAACGCGTGCACAACGGCGATCGGCCGTACAAGTGTGACGTGTGCGGCAGAGACTTCCGTCAGTGGAGTGACCTCAAGTACCACAAGGTGTCCATACATTCCGACCAGAAAATGTTCAAATGCGAGTTCTGCGGCAAGGAGTTCGCTCGCAAGTACTCGCTGAACGTGCACCGGCGCATCCACACCGGCGAGAGGAACTACAAGTGCGAGTACTGCAACAAGACCTTCCGAGCCTCCTCTTACAGGCTCAGTCACATGAGGACACACACAGGTGACCGGCCGCACAAATGTCCGCAGTGCGACAAGTGCTTCCGTGTGGCCGGAGACTTGCGGAGGCACCTCCTCATCCACGACAAGGTGCGCAACCGCCTGCACGACACCAAGACCAAGCTGAAAGACCTCAAGGAAGACAAGAAAACAACCATCAAGCAAGAGGAAAAACCAAGCATCAAGATCGAAGAAGTCGAAGTCTCAAAGAACATCAAAAAAATCGCTCTCGCTTCCACAACCAAATCACACAATAATATACTCAGAACTGTTCTCGAGAagaaaaaacctaataaaaagaaTCAGAGTGTCAAAAAAGGAGCTCCCAACGTTACCATCGACCAATTAGATGAGAGCTATACAAATAACGTAGAAGTATTTGACACAAGGCAAGATACTTACGGGAAACTCAGCGTCGTGTCTGTTAAAGAAATCTACAACGACGGGCAATACAAGCAGGACCTAGACAACCCGTTCACCAAGCAAATTATAGCTAATTACAAAGATGAACAAACTCAGGAGAGGGAACTCGCGATACTAAGACCTATGTTCAGGAACAACGTGCTATGTGACACTGTGGAGCCTGACCAAGCTGTGTTTAGGACTGAGAACACGGATGGGAAGATGCAAGTGTATACTCACATAGAGAAAAACAACACGATAGTTCCTAGTTCCCAAGTATCATTAAGCGACATTAGACATCTTGAGCGAGAAGTTAGGAGCGATATTCATGGAGAAACCACGGAGAACGGGTTCATAGAAAGGCTAACAGCGTTGTACAATATACCCGCTGTATGA
Protein Sequence
MDEAVTHYITSHPADQAVHVDGNALALNVQDDGGSRVAIMHSQTYSTSMCRQVSVGDHVVEGQWNDEIMDEGRLAAFMAHITAQQSRGQQLHHKVHTVRGDVDSSIILDGSMRLFHGQSMDQSQEPIVVEVPPLPPLPPLQEMKRCQDNDWFNNKAKPSLKDDSSMIDSDGPVLELGAGASPGQHKLQSKKSLPHKKRISRKLKKNNGNSTPQQDIVVISCTDVEGRISCADHGQEQEILPDNFVQQEHLPDETHHITHEVRPIFICQLCGEFYGDEQLKFYHHLKQHYEPHIIIENPVQDLGIDKMTNSCIVDNVTTIPDSIVELSLENSIPKTIYQSMDKNVLYTTSDKTFTYTNNKVQYSMASMDKEPPTVVQEVEKTDLYDTLDKLDLYSCGKCNKSFRKQKQCEAHIKEAHSNMKLEDMGEFSEPEDLMEGIHVAVDEPPEHYDHALLPHLTVENGHAHQDNGRQWYGRHASGAPSAGGGLGAACCAVCAAAPHDSHHLKLLKDEVLRRILETDVVTTDSQNFTDSTMTDTADTTDLPPDEPPADEKTDDKKKQKKFECQQCQRVFQHRNSLLYHMLSHSSKQHMCRECGKGFYTVAALKIHKRVHNGDRPYKCDVCGRDFRQWSDLKYHKVSIHSDQKMFKCEFCGKEFARKYSLNVHRRIHTGERNYKCEYCNKTFRASSYRLSHMRTHTGDRPHKCPQCDKCFRVAGDLRRHLLIHDKVRNRLHDTKTKLKDLKEDKKTTIKQEEKPSIKIEEVEVSKNIKKIALASTTKSHNNILRTVLEKKKPNKKNQSVKKGAPNVTIDQLDESYTNNVEVFDTRQDTYGKLSVVSVKEIYNDGQYKQDLDNPFTKQIIANYKDEQTQERELAILRPMFRNNVLCDTVEPDQAVFRTENTDGKMQVYTHIEKNNTIVPSSQVSLSDIRHLEREVRSDIHGETTENGFIERLTALYNIPAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00908231;
90% Identity
iTF_00888594;
80% Identity
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