Basic Information

Gene Symbol
-
Assembly
GCA_963576905.1
Location
OY756430.1:3415872-3419588[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.055 5.6 8.9 6.1 2 23 389 411 388 411 0.95
2 21 1.6 1.6e+02 4.3 5.6 2 23 418 439 417 439 0.95
3 21 0.00039 0.039 15.6 1.1 1 23 445 467 445 467 0.97
4 21 0.083 8.4 8.3 0.6 1 23 473 495 473 495 0.96
5 21 0.9 91 5.1 0.2 1 23 503 525 503 525 0.93
6 21 2.1e-05 0.0021 19.6 0.9 1 23 531 553 531 553 0.98
7 21 0.39 40 6.2 1.7 3 23 561 581 559 583 0.82
8 21 1.4e-05 0.0014 20.2 1.2 1 23 614 636 614 636 0.99
9 21 0.00017 0.017 16.8 1.5 3 23 646 666 644 666 0.96
10 21 0.0061 0.62 11.9 2.2 1 23 673 696 673 696 0.95
11 21 4.8e-05 0.0049 18.5 1.3 2 23 770 792 769 792 0.96
12 21 4 4e+02 3.0 5.5 2 23 799 820 798 820 0.96
13 21 0.00052 0.053 15.2 1.2 1 23 826 848 826 848 0.97
14 21 0.0029 0.29 12.9 0.6 1 23 854 876 854 876 0.94
15 21 0.0012 0.12 14.1 3.0 2 23 884 905 883 905 0.97
16 21 0.00036 0.036 15.8 2.1 1 23 911 933 911 933 0.97
17 21 0.28 28 6.6 0.9 1 23 939 961 939 961 0.97
18 21 0.00097 0.098 14.4 6.4 1 23 997 1019 997 1019 0.98
19 21 0.01 1 11.2 3.6 1 23 1030 1052 1030 1052 0.98
20 21 0.0055 0.55 12.0 4.7 1 23 1058 1080 1058 1080 0.99
21 21 0.0002 0.02 16.5 1.2 1 23 1086 1108 1086 1108 0.97

Sequence Information

Coding Sequence
ATGGAGCATTCAATAAATTTGGATCAAATTCCTTACAATATACAATCACACCTAACTTGTGAGGATCCTATAAATCTCAACACCAATTTTCAAAGAAATGTATTCCTCACCCAGCGAACGCAAGAATCATTTGTTACCCAAAAGACCCACGAGACAACAACTACATATATCGCCCAGAGACCTGCCTCCTATATTGCTCAAAAAGGCCAAGAGACGTATATACAACAAAAGAATCATGCACCATACATTGCGTCCAAAGGGCAAGCATACATTGCTCAGAAAAATCAAGAAACTTACATCACTCAAAAAAGCCAAGAGGTTTTCAAAACACAAGAGGCATTCATACTCCCAAAAGTTCAAGAGACTTTCATAATTCCCAAAGGCCAGGAGACATTCATCATACCGAAGAACACTcaagatacatacataataccaGATAAAACTCCCGAGGCATATATTGTACCCAAGACACAAGAATCATACATTATAACCAAAGATCAGACATCCTATATAATTCCCAAGAATCAAGAGTATATCATCCCTTCTAAAAGCCAAGAGTTTATCATTCCTAAATCTCAAGAGTCCTACATAGCCCAGCAGAAGGACAACGAAATATATCTGATCCCTAAAACACAGTCCTACATCATTCCCAAGGGACAAGAAACAACCTACATTACTCCGAAAGGTCAGGAGACCTACATTGTGCCTAAGACACAAAATTACATCATACCTAAAACGCAGGAAACTTTTCTCATTCCCAAAACTAGTCAGGATGGATATTTGGATTCAAAACCACACCAAGAAACTTACATGATAGCTCACAAAGACCCCACACATTTGATGCAAAAAGATTTGGAAGGAATCGCTTACGAACGCAGGCCTGAAGATGATTATTATTTGATACAAGTGACCGTGGCGGATGACGCTCAGAGCCAAGTGTGCGATAAAGATATTGATAAGAGACACGACGCCGGCAACATCATACATCTGGAAGTCAACAAGAGAGATGGGACACTTCAGACAACCAGTCTTCAGCCAACCATCCACCATCAGGCGGTCTTGCAGCATCAGCACTCGCAGAAAGAGGACGATTTGCCGGGCTTAGAATCACTGACGCAATTCACCGTGTCCGATAATGATAAAATCACTCAGACCAAGCCCATCTCTTGCGACGAATGCTCCTACAGTTGTCGTTTTGCCAGCTCTTTGAAGAAACATAAGAAGAATTGTCACACCAAGGGTAACATTTTGAACTGTGAAATGTGTTCCTATACGTGCAACAAGAAGAGAGATATGAAGCACCATGAGCTGTCTCACCTGAGGTGGACTAAGTACGCCTGCGACCAGTGCGACTACAGGTTCCAGTCTCAGAGCAAACTGGAGATACACAAACTCAAACACACCAAACCTAAGCCGTTTAACTGCAGTGCTTGCAGCATGCAGTTCCAAAGGCTGGACGATCTCAAGATACACAACTTGACTCACATAGAACCCGGCAAAGATCTCTTCATGTGCAACGATTGCGGGTACTTACCCAAAGACGACACCGATTTGGAAGAGCACAAGAAGTCACACGGGGGGGATAAAAAGTTTTCTTGTGATATTTGCGGGTTGAAATTCAAATATCAGGTGACTCTCAATGGTCATATGAAGAAACACGAAGAGAGAAAGTACTACGGATGCAACCAGTGCAGTTACGTCACCAGTAAAGTGTTCTGTTTGAAGAATCATTTGAAGGCTCATATGGATAATACTGTGAAAGCGGAGCCGGTGGCCAAGAAGTGTAAAAAATTAGTTTCTAAAAAACCCATCATGAAAACAAAATCCGAGGACAGACCGTACGAGTGTGACCAGTGCGGGTTTGCAAGTAAGAGGAAGTTTAATCTACAGACACATATGAAAGTTCACGAACCAGCGACCGGAGAGTCTTTGTTCTGTAACGAGTGCAACTATTCTACAACCAGAGAACGCTACCTTAAGAAACATATGATAATGCACCAAACTAAATCTAAACCTTTCATTTGCAACCTTTGCGGATACACTTGTAAAAATCCCAAGGTTTTTAGAAAGCACAAGCTCGTAATCCACGAGATAGAGGAACCTGATCCGGTAAAGGATGATAAGTCCAAAGAATATCAGGAAATGGCAGAGATACGTAGAAAACTTTCTAAACAAAGCTATCTGGTAACACTCGTCACCGTCGGGATCCAAACTGATCCCATCCCGGAGGAGGAGCTGGTGAAGGAAAACGCTATTAAGGAAGAAGTGAAACCTAAGAAGATGAAAAATGAAAGTCCCAAACCTGTCACGTGTGACATATGTAACTATACTTGTAAATATCCCAGCACTCTCAAGAGACACATCCTCAGTGTCCACACCCAGCAGAACGTCCTCACGTGCTCCTCCTGCAACTACACCTGCGGCAAGAAGAGGGATATGAAACACCACGAACTCATGCACAGACGGCTGAGAAAGTTTGCCTGCGATCAGTGTGACTACAGGTTCCAATCGCAGAGTAAACTGGAAATACACAAACTAAAACACACTCAACCGAACCCGTTCACTTGCAACATTTGCGGAGTGCAGTTCCAGAAGTTGGACGATCTCAAAAATCACAACTTTGTGCATTCGGACGGTAAACCCATGATCGTGTGCGACGATTGCGGATATATCTGCAGCCATCCGTTTGAGCTGGAGAATCACCGACACACTCACGTCAACGAAAAGAAGTTTGCTTGTCAAGAATGCGGGTTGAGATTTAAGTATCACGTGACATTGAACGGTCATATGAAGAAGCATCAGCAAAAGAAACTGTTTGCGTGCAATTTGTGTTCTTTTGTCGCCAGCAAAATGTTTTACTTACGCAAACATGTGCAGTCACATTACGAAGTGAAAAAAACCAGCTGCGATCAGTGCGGATTCGTTCCAAAGAATCCTACGACCACTGCTTTAAAGTTGCACATGATGACACATTCTTCGGAGAAACCTTTCAATTGTTATGTGTGTTCGTTTACCTGTAAGACCAAATCGAATTTGAGGATGCATATGAAAAAGCATAACCGCGTAGTTCCGGAAAAGGCCAAATTCTTCTCTTGCCGGCAGTGCAAGTATACGTCGACAAAATCAAAGAATTTCAGACTCCATATGCTGATACATCGTGAAGACGAGCCGTATAAATGCGACACATGCGGTTATACTTGTAAATTGATGAGTTATCTCAAATCGCACAAGTTAACCCACGCCGCGGTGAAGCCACATCCGTGTGATCAATGCGAAAAGAGTTATCGTACGGCGTTTGATCTGAAAGTGCACAAAATGATTCACCGAGAAGATCCTTTTGCATGTGACGAATGTGACTTCAATACACACTGCTTCACAAATCtgtataaacataaaaaagaacACGTGGCGAAATCAAAGAAGGAAAAAGAGATGCAAGGGATACACAAAGAAGAGCACCCTCTGGTTGTTATCGAAATTAAGGACGTTCAAAATCAGCAACAATTAAACATCGGACAGCACAGCATGATGGATCAAATCGACATTGATCAGATACAAATACACAACGGACAAGCGTTGGACGCTCAAGGACAACTGATAACTTTAGACGCTAACCTGACGTCACAACTGCATCCACAAATACACATTCAGCAACAGTTGCAAATGCAGCAGATGACTCACGTTCAGACGCACGCCAACAACATGCAAGTCGGCTAA
Protein Sequence
MEHSINLDQIPYNIQSHLTCEDPINLNTNFQRNVFLTQRTQESFVTQKTHETTTTYIAQRPASYIAQKGQETYIQQKNHAPYIASKGQAYIAQKNQETYITQKSQEVFKTQEAFILPKVQETFIIPKGQETFIIPKNTQDTYIIPDKTPEAYIVPKTQESYIITKDQTSYIIPKNQEYIIPSKSQEFIIPKSQESYIAQQKDNEIYLIPKTQSYIIPKGQETTYITPKGQETYIVPKTQNYIIPKTQETFLIPKTSQDGYLDSKPHQETYMIAHKDPTHLMQKDLEGIAYERRPEDDYYLIQVTVADDAQSQVCDKDIDKRHDAGNIIHLEVNKRDGTLQTTSLQPTIHHQAVLQHQHSQKEDDLPGLESLTQFTVSDNDKITQTKPISCDECSYSCRFASSLKKHKKNCHTKGNILNCEMCSYTCNKKRDMKHHELSHLRWTKYACDQCDYRFQSQSKLEIHKLKHTKPKPFNCSACSMQFQRLDDLKIHNLTHIEPGKDLFMCNDCGYLPKDDTDLEEHKKSHGGDKKFSCDICGLKFKYQVTLNGHMKKHEERKYYGCNQCSYVTSKVFCLKNHLKAHMDNTVKAEPVAKKCKKLVSKKPIMKTKSEDRPYECDQCGFASKRKFNLQTHMKVHEPATGESLFCNECNYSTTRERYLKKHMIMHQTKSKPFICNLCGYTCKNPKVFRKHKLVIHEIEEPDPVKDDKSKEYQEMAEIRRKLSKQSYLVTLVTVGIQTDPIPEEELVKENAIKEEVKPKKMKNESPKPVTCDICNYTCKYPSTLKRHILSVHTQQNVLTCSSCNYTCGKKRDMKHHELMHRRLRKFACDQCDYRFQSQSKLEIHKLKHTQPNPFTCNICGVQFQKLDDLKNHNFVHSDGKPMIVCDDCGYICSHPFELENHRHTHVNEKKFACQECGLRFKYHVTLNGHMKKHQQKKLFACNLCSFVASKMFYLRKHVQSHYEVKKTSCDQCGFVPKNPTTTALKLHMMTHSSEKPFNCYVCSFTCKTKSNLRMHMKKHNRVVPEKAKFFSCRQCKYTSTKSKNFRLHMLIHREDEPYKCDTCGYTCKLMSYLKSHKLTHAAVKPHPCDQCEKSYRTAFDLKVHKMIHREDPFACDECDFNTHCFTNLYKHKKEHVAKSKKEKEMQGIHKEEHPLVVIEIKDVQNQQQLNIGQHSMMDQIDIDQIQIHNGQALDAQGQLITLDANLTSQLHPQIHIQQQLQMQQMTHVQTHANNMQVG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-