Basic Information

Gene Symbol
-
Assembly
GCA_963576905.1
Location
OY756431.1:12685621-12687434[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.019 1.9 10.3 4.8 1 21 134 154 134 157 0.94
2 11 6.3e-06 0.00063 21.3 0.7 2 23 163 184 162 184 0.97
3 11 3.5e-06 0.00036 22.1 1.9 3 23 193 213 192 213 0.99
4 11 8.3e-05 0.0084 17.8 0.3 1 23 219 241 219 241 0.96
5 11 5.3e-05 0.0054 18.4 0.1 1 23 247 269 247 269 0.98
6 11 0.0002 0.021 16.5 0.9 1 23 275 298 275 298 0.95
7 11 0.00031 0.032 15.9 0.7 1 23 304 328 304 328 0.97
8 11 0.00038 0.039 15.7 3.5 1 23 334 356 334 356 0.99
9 11 0.00012 0.012 17.3 0.5 2 23 363 384 362 384 0.97
10 11 0.0091 0.92 11.3 3.0 1 23 390 413 390 413 0.97
11 11 0.00025 0.025 16.2 2.0 1 23 418 440 418 440 0.98

Sequence Information

Coding Sequence
ATGAGTGATCTAGAGCAAATATCAACTGCTAAAAATGAACAAGATAATTTGGACGTGATATGCCGATTGTGTATGAAATATAATTCAAATATGCAATGCATCTTTGAAgcagaaataaatgaaaatgatGTAGATTCCCACAGTACAATAGTTCATAATGATGGTCTTCCTTCTCAGATTTGTAATAACTGTGTTGAAAATGCCAAGAActcttataaatttaaaaaacagtGTGAAATATCAGATCGgcatttaagaaaattaatagaaaacaATGTGTTTGAAGGAATTTTAGATCAACCCACATTAGAAGATGATAGAAATGATAAAACAATTGACAGGCGTAAAAATGTAAAAGATGACAATAAAAAGGAAAATAGGTGTGAAAATTCACCTCCCTATTCGTGTCTTGATTGCTCTAAGGTGTTTCGATCTGTAAAAGTTTtacaaaaacatttaaaatgtcatcaCAAACTCGCCAAATTAACTTGTGAAATATGTGATCAAACTTTCTCCCAACCTCAAACTTTATCCAGGcataaaaaaattcatcaagaaaatcaaagaaataatCTGTGCACTGTATGTGGGAAAGGGTTTCATCGGAGTGATGATTTGAAAAGGCATGCTCGAACTCACACTAACGAAAAACCGTATACGTGTATTCTGTGTCCTAAAAGTTATAAACAATCCTCGGAATTAGCAGATCACGTTAAAACACATTCCTCTATGAAGAATTATGTTTGCAGCGAATGTGGTAAAGGTTTGGCCACTCGTAACGGTCTCTACATCCACATGAAAGTTCACAGGGGAGAAAAGAATCATGAATGTAAAATATGCGGAAACAAATATGTGACTGCAGGAGAGTTGAACTCCCACATAAATCATATACACTCCCATCAGAAGCCTTTTGTTTGTTCATTTGTAGGATGCAGCAGGGCGTTTGTAACTAAATTATCTTTGCAAACCCACACTAGGAGTCACACGGGTGAAAAACCTTATCAGTGTTGCATTTGTCATAAATATTTAGCTTCCCCTTCATCTCTACAAGATCACAAAAGGATTCATTCTGGTGAAAAACTTAAAACTTGCAACATTTGTGGACAAAAACTTGGCAATTCACAAGCATTGAAAAAGCATCTgagaattcatagcggagagcGTCCTTACCATTGTGATATATGTTGGGAATCTTTCATTTGCCGTTCATCTCTTAGCTCACATATAAAAATCAAGCATATGAATAAAGAGCACCAATGCGTACAGTGTAAGAAATTATTTGCTCTCCCATCAAAATTAAGACAGCATATGAAAATACACAACAAACAGGATCAAATTTCGTTCAAAGAGTGTGGGGAAAGTGGAATAAAACCAGTTCAAAATGAACCCAGCGATAGATCTTCATTTTTAGATCTTTATAAAGACTCTCCCAATCTTAATTTGGATAGTGCCTCATTAGAATTAGGAGATTCCCAAGAAAACTTCAAGAAAAAGCATTGTCATTTAGAATTGCCACAAAATGAAAGTGTAATTTCTGTCTCACAaataactattccacaaattggTACATCACAATATCTCTAA
Protein Sequence
MSDLEQISTAKNEQDNLDVICRLCMKYNSNMQCIFEAEINENDVDSHSTIVHNDGLPSQICNNCVENAKNSYKFKKQCEISDRHLRKLIENNVFEGILDQPTLEDDRNDKTIDRRKNVKDDNKKENRCENSPPYSCLDCSKVFRSVKVLQKHLKCHHKLAKLTCEICDQTFSQPQTLSRHKKIHQENQRNNLCTVCGKGFHRSDDLKRHARTHTNEKPYTCILCPKSYKQSSELADHVKTHSSMKNYVCSECGKGLATRNGLYIHMKVHRGEKNHECKICGNKYVTAGELNSHINHIHSHQKPFVCSFVGCSRAFVTKLSLQTHTRSHTGEKPYQCCICHKYLASPSSLQDHKRIHSGEKLKTCNICGQKLGNSQALKKHLRIHSGERPYHCDICWESFICRSSLSSHIKIKHMNKEHQCVQCKKLFALPSKLRQHMKIHNKQDQISFKECGESGIKPVQNEPSDRSSFLDLYKDSPNLNLDSASLELGDSQENFKKKHCHLELPQNESVISVSQITIPQIGTSQYL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-