Basic Information

Insect: Myrrha octodecimguttata
Gene Symbol: topi
Assembly: GCA_958510865.1
Location: OY294059.1:59333937-59337270[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0022 0.37 12.6 2.1 2 21 126 145 125 146 0.94

2 14 5.7e-05 0.0093 17.6 2.4 1 20 171 190 171 193 0.94

3 14 0.0094 1.5 10.6 2.0 3 23 201 221 200 221 0.95

4 14 0.038 6.2 8.7 0.4 2 20 240 258 239 260 0.90

5 14 7.3e-05 0.012 17.2 1.0 2 23 318 339 317 339 0.97

6 14 6.3 1e+03 1.7 0.2 1 12 345 356 345 358 0.88

7 14 0.0011 0.19 13.5 2.7 2 22 382 402 381 405 0.89

8 14 0.14 23 6.9 0.1 1 23 523 546 523 546 0.93

9 14 0.13 21 7.0 0.9 1 23 550 572 550 572 0.91

10 14 7.5e-07 0.00012 23.5 2.4 1 23 578 600 578 600 0.98

11 14 0.021 3.4 9.5 0.2 1 23 606 631 606 631 0.96

12 14 0.35 57 5.7 2.5 1 23 637 659 637 659 0.85

13 14 4.7e-05 0.0078 17.8 1.5 3 23 667 687 665 687 0.97

14 14 6.7e-07 0.00011 23.7 1.0 1 23 693 716 693 716 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0022	0.37	12.6	2.1	2	21	126	145	125	146	0.94
2	14	5.7e-05	0.0093	17.6	2.4	1	20	171	190	171	193	0.94
3	14	0.0094	1.5	10.6	2.0	3	23	201	221	200	221	0.95
4	14	0.038	6.2	8.7	0.4	2	20	240	258	239	260	0.90
5	14	7.3e-05	0.012	17.2	1.0	2	23	318	339	317	339	0.97
6	14	6.3	1e+03	1.7	0.2	1	12	345	356	345	358	0.88
7	14	0.0011	0.19	13.5	2.7	2	22	382	402	381	405	0.89
8	14	0.14	23	6.9	0.1	1	23	523	546	523	546	0.93
9	14	0.13	21	7.0	0.9	1	23	550	572	550	572	0.91
10	14	7.5e-07	0.00012	23.5	2.4	1	23	578	600	578	600	0.98
11	14	0.021	3.4	9.5	0.2	1	23	606	631	606	631	0.96
12	14	0.35	57	5.7	2.5	1	23	637	659	637	659	0.85
13	14	4.7e-05	0.0078	17.8	1.5	3	23	667	687	665	687	0.97
14	14	6.7e-07	0.00011	23.7	1.0	1	23	693	716	693	716	0.98

Sequence Information

Coding Sequence: ATGAGAAACTCAGATAATCTTATTTTCAAAGTTTATAAAATAAACCACAATGGAATAATTTCAGCAGTGGAATATGAACAGGATTTTTACACCCGCGAAGTTCTTTTCAAAAGGCATATTTCAGGTCAAGAACCAACTCCAAATTTACATTCTGATCCTGAAAAGCTTAAATTGAGCTTCAGTAATTTTGAATGTGAAGATGAGAAGAACCCCCTTGTGAGTTTTGTGAAGGTTGAAAATATCAGCGATGTAAGTTTAATTCAGACCAGCGGATACTCTTGtccaaaaaatttcgttttccgaGGTAAGAGAAGTATTTCCCCACTTTACTTACATCACCAGATGAGAATTTCCCTGAATATTCCCACTATGATAAGGTGCCAAAATTGTGAAAcgaattttccaacaaaatacCAATATCAGAGGCATCAGTGTGAATTTAATGCGGAAAAAGTAGTTTTAAAAGCAAATGCTGATTTGAAAGATATAAATAAAGGTATGAGAATAAAGTATGATTGTGATAGATGTGGAAAACAGTTTGTGAGTAAGAATAATTTAGAGAGACATCAAATTTGTCATGataattcaaaagaaaatatatgtGAACATTGTAATAAACAGTTCGTTAGTGAAAACAGATTAAGAATTCATAAGGAGAATCATTGTAAGAAAGTTGGAGATATATCTAAGTTTTATCGCAGTGATGTTGCTGTATGGAAATGTAGGAAGTGTCATGAAGTATTTTCTTCGTTGAATTCTGCAAACACTCATGTTGAATCTTGTCAAGAAGCTATATACCAGTTTGACCAGAGTAATCCCAAGATTGATTCTGATCATCAGGGAAAGGAAATGTCTTGTGTGGTATCAACATCCGTTACAAATGATGATTCAACAAATGTAAAATTATTAGATGAAAGTCAAATTGAGAGAATTCTTACAGAAATACTTTTACAATGTGAATTTTGCAATCGAACTTATGCAGATAAAAATTTGCTTTTGTTACATCAAAGAAAACATTCAACTGCTAGGAATTATGAATGTGTCAATTGTAACAACAGCTTTGAGTCTTATGCTATTGCGGCTCAGCACTGGTTGAAAATATGTTCCGAAACTTCGAATATGTTTTATCTTCCCAAATTAACCTACTGTGAGTATTGTGATCGTACATTTAAATCACATGAGTTATTATATGCACATAAAATAAAGAAGAAACATTATACagtcaaattattcaaaaacgaTTCGCATTTAGGCCAGAATAGTGCAAGAGAAAAACAAATTGACAGTAGTGAAGCTATCAATAAACTTATTGAAGATGTTTTAATAACATTAGATAGGCCAATAGGTAAAATATGTTCACTTTCTAAACCTGATTATGATGATTCAAATAAGGAAAATATAGAGGCTAATTATATGCAAAAGGATTTGAGTGATGCACCTGGAGAATCTAGTCAGAATGAAGTGTCTGATAAACCGGAAAAGAAAAAAAGGGGGCGCAAGCGGAAATGCTCCAAACCTGGAATCAGAAGTAAAAAATTACAAAGTTTGATTAATGAAGGGTACAAGTATCAGTGTGAACGATGCCCACTTGTATGGGATAACATATCTGACTTAGAAAAGCATAGAGATCAAGAGCATGCTGCAAGTTTTAGTTGCGAAGACTGTGGACAGATATTGCACAGTGCTAAAGCATTGCTTATCCATTGTCGTGCTCATAAGTGTTTGAAGCCATATGTTTGTGATACTTGTGGAAGAAGTTATTCCCAAACATCTCATCTATGGCAACATATGAGATTCCATCAAGGTATAAAACCCTTTGCATGTCCACATGAAGGTTGTGAAGCTAGATATACTATTCGTCCAGATCTGAAGGATCATATAAGAAAGGTGCATACAAGAGAAAGGCCCTTCAAATGTGCAGTTTGCAATAAATGCTTCTTAACAGGATCTGTGTATTACCAACACCGTTTAATACACACCAATGATAGAAGATATGGCTGTGAAGTATGTCACAAGAGATTTTTTAGGGCCGATGCTTTAAATAACCATAAAAGAATTCACACCGATGAGCGCCCATATCCTTGCACTGTATGTGGGAGAGAATTTAGACAGAAAGGGGATCGTAATAAACATATGCGTACTCAACATCCAGAAGCTGTTGTTCAGTGA
Protein Sequence: MRNSDNLIFKVYKINHNGIISAVEYEQDFYTREVLFKRHISGQEPTPNLHSDPEKLKLSFSNFECEDEKNPLVSFVKVENISDVSLIQTSGYSCPKNFVFRGKRSISPLYLHHQMRISLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKANADLKDINKGMRIKYDCDRCGKQFVSKNNLERHQICHDNSKENICEHCNKQFVSENRLRIHKENHCKKVGDISKFYRSDVAVWKCRKCHEVFSSLNSANTHVESCQEAIYQFDQSNPKIDSDHQGKEMSCVVSTSVTNDDSTNVKLLDESQIERILTEILLQCEFCNRTYADKNLLLLHQRKHSTARNYECVNCNNSFESYAIAAQHWLKICSETSNMFYLPKLTYCEYCDRTFKSHELLYAHKIKKKHYTVKLFKNDSHLGQNSAREKQIDSSEAINKLIEDVLITLDRPIGKICSLSKPDYDDSNKENIEANYMQKDLSDAPGESSQNEVSDKPEKKKRGRKRKCSKPGIRSKKLQSLINEGYKYQCERCPLVWDNISDLEKHRDQEHAASFSCEDCGQILHSAKALLIHCRAHKCLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCNKCFLTGSVYYQHRLIHTNDRRYGCEVCHKRFFRADALNNHKRIHTDERPYPCTVCGREFRQKGDRNKHMRTQHPEAVVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00349527;
90% Identity: -
80% Identity: -