Basic Information

Insect: Mylabris variabilis
Gene Symbol: ZFHX3
Assembly: GCA_037464815.1
Location: JAZBGW010000773.1:11963-18003[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.34 20 5.8 0.3 2 23 153 175 152 175 0.94

2 17 0.00017 0.01 16.2 1.8 2 23 318 340 317 340 0.95

3 17 4.2e-05 0.0025 18.1 0.7 1 23 372 396 372 396 0.92

4 17 0.0062 0.37 11.3 0.4 1 22 438 459 438 462 0.91

5 17 8.3 4.9e+02 1.5 4.2 1 20 606 625 606 630 0.89

6 17 3.7 2.2e+02 2.6 0.2 2 20 663 681 662 686 0.91

7 17 0.31 19 5.9 1.5 1 22 711 732 711 735 0.90

8 17 0.66 40 4.9 0.2 1 22 823 844 823 846 0.80

9 17 0.00039 0.023 15.1 0.4 1 23 862 885 862 885 0.96

10 17 0.015 0.9 10.1 2.1 2 22 973 993 973 996 0.90

11 17 0.062 3.7 8.1 0.6 1 23 1008 1033 1008 1033 0.91

12 17 0.0029 0.17 12.3 1.6 1 23 1051 1073 1051 1073 0.97

13 17 0.00063 0.037 14.4 0.7 2 23 1080 1102 1079 1102 0.94

14 17 0.00016 0.0099 16.3 3.1 1 23 1210 1234 1210 1234 0.92

15 17 0.0049 0.29 11.6 0.6 1 22 1254 1275 1254 1278 0.89

16 17 0.00098 0.059 13.8 0.2 1 23 1332 1356 1332 1356 0.93

17 17 0.00091 0.054 13.9 0.1 2 21 1424 1443 1423 1444 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.34	20	5.8	0.3	2	23	153	175	152	175	0.94
2	17	0.00017	0.01	16.2	1.8	2	23	318	340	317	340	0.95
3	17	4.2e-05	0.0025	18.1	0.7	1	23	372	396	372	396	0.92
4	17	0.0062	0.37	11.3	0.4	1	22	438	459	438	462	0.91
5	17	8.3	4.9e+02	1.5	4.2	1	20	606	625	606	630	0.89
6	17	3.7	2.2e+02	2.6	0.2	2	20	663	681	662	686	0.91
7	17	0.31	19	5.9	1.5	1	22	711	732	711	735	0.90
8	17	0.66	40	4.9	0.2	1	22	823	844	823	846	0.80
9	17	0.00039	0.023	15.1	0.4	1	23	862	885	862	885	0.96
10	17	0.015	0.9	10.1	2.1	2	22	973	993	973	996	0.90
11	17	0.062	3.7	8.1	0.6	1	23	1008	1033	1008	1033	0.91
12	17	0.0029	0.17	12.3	1.6	1	23	1051	1073	1051	1073	0.97
13	17	0.00063	0.037	14.4	0.7	2	23	1080	1102	1079	1102	0.94
14	17	0.00016	0.0099	16.3	3.1	1	23	1210	1234	1210	1234	0.92
15	17	0.0049	0.29	11.6	0.6	1	22	1254	1275	1254	1278	0.89
16	17	0.00098	0.059	13.8	0.2	1	23	1332	1356	1332	1356	0.93
17	17	0.00091	0.054	13.9	0.1	2	21	1424	1443	1423	1444	0.94

Sequence Information

Coding Sequence: ATGCCCACATTGTCCGCGGCGACTGAGCTGAGTCCCGGCGGCCGCACCGAGCGGCATAATCAACAAGACGAAACCGCCATGAGCCCAGAGCAGGAGGCAAGTCCACCACCTGCAGCGCCGGGAGCATCTCCGCCTCCGCCGCCTCCAACACGTCTCCCATCACCAGCAATGTCTCATCAAGATACTTCTGATGTGGAGCAATTCTCTGGGAAAATTGTTTACAATCCTGATGGATCAGCTTATATTATCGAAGATTCAGAAAGTGATAGCGAAACAATTGGCGCCAACACCAATGTTCCAGATATTGTACCACCTTTACAGGCCGTGTATGTGTCGCGATTATTACGACAAACAACAAGACCTACCGAATTGCCGGCCGTCCATAGTTATCGTGTGGTAGCACTTCGGGACGCAAGACCACCTAGGCCAGCATCAGTTCCTGTTAAACCAATCCTAATGTGTTTCGTATGTAAATTGAGTTTTGGTTTTGCGCGTTCGTTTGCCAATCACGCACAATCCGAACATGGAGttacattaaaagaaaacGAACGTGAAGTGTTGGCCGCAGACTGTTCCGCGATCCTTCAGTGTGTGGGGGCAGATAAAAGACCTATAGTGTCGTTATTAGAACCGCTCGGTACCGCCCAGGACATTCAAAATACACAAACGATACCAGTGACTTCGATGCATAGTAGGAACGACGGTACCTCACCTCATTCTGAAACGCCGCCGTGTTCTACGTCTCGAAATACACCGGGTAaatcaccatcaccaccattTGCACCACCACCAGCATTTATGACTGGTACAACAATAGGTGTTTGTCCAGAACATCTACAGGGACGGCCATCGGGTGTTGAATGTGCCAGATGTGAAATGATTTTAGCATCAGGTAGATTAGGACCAGCAGGATTAGCGAATGTTCATAGTCGAAATTCCTGCAAAACGCTCAAATGTCCTAAATGCAATTGGCATTATAAATATCAAGAAACATTAGAAATACATATGAAAGAGAAACATCCAGAAGCGGAAACTAgttgtatttattgtattgcCGGTCAGCCGCATCCGCGATTGGCGCGAGGTGAAACTTATACATGTGGATACAAACCATACAGATGTGAAGTCTGCAATTAttcgacaacaacaaaaggCAATCTCAGTATACATATGCAATCTGATAAACATCTCAATAATATGCAGGAATTACAGAATGGGGGAGCACCCAATACTGAACCTAGGCAATCATCCCCTAAAGCACCCCCTTTACATCATTCTCCTGTTAGTAGTGGTCATAAGCCAAAGCCGAGTTTTCGTTGTGATGTTTGTAATTATGAAACAAATGTAGCAAGAAATTTACGAATACATATGACATCTGAAAAACACACGCACAATATGCTTGTATTACAACAAAATGTCAAACATATGCAAACTCTATCAGCATTACACCATCAACAGCATCCACAACAGCATATTGAAAATCTCTATGGAATGTATCCAGGTTTAGGTGATAAGCCAGAAGCGGCTCTTGCTGATATGGCGTATAATCAAGCATTATTAATACAAATGATGACTGGCGGTCAATTGCCTGGTCATGGGGCACCAACTGATATGTCAGCCCATTCTGATCTTGGTCTAAATCCTGAAACAATGGAACCACCCCCTGAACCAGCCGATCCTGATCCAGAACGTACCTATCAGTGTTGTGTTTGTAATGTGTTCATGACAGACAGTTTAGAAGAATTAGGAAGACATCTAGCACAGGACCGTACTCGATTGAGAGAACAAGAAATTTTGGCTGTTGTAGCCGGCCATTATGTATGTAAATTATGTAcatacaaaacaaatttaaaagcCAACTTCCAACTACACTGCAAGACTGATAAGCACTTACAGAGACTGCAACACGTCAATCACGTGAAAGAAGGTGGCAATAGAAATGAATGGAAATTAAAATATGCTTCAGCGCCTGGTGGTGTTCAAATACGTTGTAATGCCTGCGATTATTATACAAATTCAGctcataaattacaattacatgCTGCTGCTGGCCGACATGATGCCAGCGTAGCACTTCTAAAACATTTGGTAGAACGATGTGCTGCACTAAGAACAGATCAACCGAAAGTGTATCATTGTTCGCTTTGTGGATTTTCAACAACCAACCGTCTACCATTATTGCAACATGTTAAATCACTCAAACACCTTCATATGGAGCAACTGCATCAACTACAGCGGCGTGCTGAAGGTAAAGAAAATTCACCAGAAATTGGTGAAGTGTTTCACGTTGTACCTGGACTTATCGACCAACCACAACCACATCAACAAACACCTGAACGTAGAAATAGCGTCAATTCAGAAATTAGTCAGTTGGAATCGTCATCGAGTAGAGAGCAACATGTAAAAACTGAACCTCGCGAAGACAACGAAGATATGAACAATTCTGAGAGTGGATCATCACCACAACACGTTTGTCCATATTGTGATTATAGTAGTGATTCAGAAATGAGAATACAAGCACATGTTTTAGCACAGCATAGTAATAACAgcagtaataatagtagtgcTTCCGCGGACCAAATATTCCAATGTCCCCTCTGTCAGGATTCGTTTAAAGAACGTTCGAGTCTAGAACGGCACGTCATGCAAATACATTCAGTTAATAGTGAAGGACTACAACGATTATTGATGTTAGTTGATCAAAGTCATTGGCTTAATCAAGCGTCAAGAACATCGACGCCAAATAATTCCACGAATCATCTACAGACACCGCCGAATCAAACGGTGTCACCTACCTCTGTGTCTTCCAAAGATTCGAATAAATTAGAGAAAAGTGACAATGCCAGTAACACAGAGGCCGATAGAGAATTAATGATGTCACCGGCCAGTGaagataataatgaattagaaTCTGAACGATGTGGTActtgttttaaaacatttaaaaatattgatgaattaTGTTTGCATCAGAACGAAACCGgtcatttagaaattaaacaaacaccCAGCGGGCCGGGCTATATGTGTTGGAAGAAGGGTTgtaatcagttttttccaactGCCAATACATTACAAATGCATTTTAAAGAGGTGCAcgcgaaaaattcaattgctAATATGTCAGTATCGGAGAAGCAcgtttataaatatagatgCAACCAATGTTCTTTAGCTTTTAaaacattagaaaaattacaattacattcACAATATCATATGATTAGGGATGCGACGAAATGTGTATTATGTGGCCGAAGTTTTCGATCATTAGTAGCACTCCATAAACATGTAGAAAGTGTCCATTCCGAATTGACTGATGAAGAATTGAACGCTTATAAACAGAGTTTGATGAATAACCCATTGTTGTTGGCCGGTTTGCAAGGTCAAGTTTTGGATAGTTCAactaatgaaattttaaaaaaagaatcattAGCAACAGACGATATTATTGAAACAACTGAATGTGATGATAGTAAAGAAATAAATACTAGCCATGATGATAGTAATCAAAATGATGGTGAAAATTCCGATGAtagtataatttataaagatcaacaatttttagaaGATTATCTAAATAGTCAAGCAATAGCTGAAGATAGTTATAATGATCCAAATCGAAAATATAAATGCCATCGGTGTAAAGTCGCGTTTACAAGACAGAGTTATTTGACTGCACATAATAAAACACTTTTACATAGAAAAGGTGAAAAACTCAGTTACCCAATGGAGAAATATTTAGATCCGAATAGACCGTATAAATGTGATGTTTGTAAAGAAagttttacacaaaaaaatattttactagTCCATTACAATTCAGTTAGTCATTTACATAAATTGAAAAGAGCCAtgcaagaacaacaacaacaaaataataataataataataacaatccaGCCGTCTCACCAATTATTGGAAGTAATCAACCacaaaatttaacattaaCACCAAAAAGTACATCATCAGAAGAAGATGACAAGAAACGTTACCgttgtaatatttgtaaagtTGCATATACACAAGGCAGTACTTTAGATATTCATATGAGAAGTGTATTACATCAGACACGGGCTAGTAAATTACAAGATTTAGCATTAGCTGGCCAGATTGACCTTTCTAAACCATTAATTGAACAGCCTGAAGCCGTGCAGTCTCCGAAACAATCGAGTCCTACACCAGGTAGTGGTGGTTGTAGTGGGGACAAGACGTCTCCCACCCCTCCATCTCCAGGTTTGGGTACAGGTAGCAGCCAAGGGATGATGAGCTGTCCCAAATGCGGTGCCCTTTTTAGTTCGCAAGATCAGTTGAGTGCACACCAGCAACTGTATTGTATGTTTGCCGCACCGATGGCCATCTTCCAAGCGGCCCAAGAACCAGGCCAGGCGAAGAGTCCACCACCTGGTGAACAAGATGATGCTGTTGTTCGATTGAATTTACCGAAAAAGACCGGTTCACATATGTACAAACATTTATTGGAAAGTTTTGGTTTCGATTTAGTAATGCAATATAATGAGAGTCATCAACGACGTCAACGGCAACGAGAAGTTGAAGAAAAGGCACGATTGCAAGCCAATACATCACCACCACCTCAACAACCGATAACGTAA
Protein Sequence: MPTLSAATELSPGGRTERHNQQDETAMSPEQEASPPPAAPGASPPPPPPTRLPSPAMSHQDTSDVEQFSGKIVYNPDGSAYIIEDSESDSETIGANTNVPDIVPPLQAVYVSRLLRQTTRPTELPAVHSYRVVALRDARPPRPASVPVKPILMCFVCKLSFGFARSFANHAQSEHGVTLKENEREVLAADCSAILQCVGADKRPIVSLLEPLGTAQDIQNTQTIPVTSMHSRNDGTSPHSETPPCSTSRNTPGKSPSPPFAPPPAFMTGTTIGVCPEHLQGRPSGVECARCEMILASGRLGPAGLANVHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGAPNTEPRQSSPKAPPLHHSPVSSGHKPKPSFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALHHQQHPQQHIENLYGMYPGLGDKPEAALADMAYNQALLIQMMTGGQLPGHGAPTDMSAHSDLGLNPETMEPPPEPADPDPERTYQCCVCNVFMTDSLEELGRHLAQDRTRLREQEILAVVAGHYVCKLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGNRNEWKLKYASAPGGVQIRCNACDYYTNSAHKLQLHAAAGRHDASVALLKHLVERCAALRTDQPKVYHCSLCGFSTTNRLPLLQHVKSLKHLHMEQLHQLQRRAEGKENSPEIGEVFHVVPGLIDQPQPHQQTPERRNSVNSEISQLESSSSREQHVKTEPREDNEDMNNSESGSSPQHVCPYCDYSSDSEMRIQAHVLAQHSNNSSNNSSASADQIFQCPLCQDSFKERSSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTSTPNNSTNHLQTPPNQTVSPTSVSSKDSNKLEKSDNASNTEADRELMMSPASEDNNELESERCGTCFKTFKNIDELCLHQNETGHLEIKQTPSGPGYMCWKKGCNQFFPTANTLQMHFKEVHAKNSIANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMNNPLLLAGLQGQVLDSSTNEILKKESLATDDIIETTECDDSKEINTSHDDSNQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQQNNNNNNNNPAVSPIIGSNQPQNLTLTPKSTSSEEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLALAGQIDLSKPLIEQPEAVQSPKQSSPTPGSGGCSGDKTSPTPPSPGLGTGSSQGMMSCPKCGALFSSQDQLSAHQQLYCMFAAPMAIFQAAQEPGQAKSPPPGEQDDAVVRLNLPKKTGSHMYKHLLESFGFDLVMQYNESHQRRQRQREVEEKARLQANTSPPPQQPIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -