Mvar007735.1
Basic Information
- Insect
- Mylabris variabilis
- Gene Symbol
- -
- Assembly
- GCA_037464815.1
- Location
- JAZBGW010004013.1:4242-5820[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 2.9e-06 0.00018 21.8 3.8 1 23 18 41 18 41 0.98 2 14 0.32 19 5.9 5.5 1 23 48 70 48 70 0.97 3 14 8.1e-06 0.00048 20.4 3.1 1 23 76 98 76 98 0.98 4 14 1.4e-05 0.00086 19.6 0.4 1 20 104 123 104 125 0.95 5 14 0.091 5.4 7.6 6.8 1 23 148 170 148 170 0.96 6 14 0.0019 0.12 12.9 2.3 1 20 176 195 176 197 0.92 7 14 4.6e-05 0.0028 18.0 3.9 1 23 204 226 204 226 0.98 8 14 0.0066 0.4 11.2 1.2 2 23 233 255 232 255 0.96 9 14 0.0011 0.069 13.6 3.3 3 23 264 283 263 283 0.98 10 14 0.0068 0.41 11.2 5.2 1 23 293 316 293 316 0.98 11 14 8.3e-05 0.005 17.2 2.5 1 23 323 345 323 345 0.98 12 14 1.6e-06 9.4e-05 22.6 1.7 1 23 351 373 351 373 0.98 13 14 2.4e-06 0.00014 22.0 0.4 1 23 379 401 379 401 0.98 14 14 1.2e-05 0.00072 19.8 0.6 1 23 407 430 407 430 0.96
Sequence Information
- Coding Sequence
- ATGAAACAACATATGAAAACACATGAAGAAGGCTACATCGAGAAACGTAATTTCAAATGCGAATTCTGTACGAAAGCATTTCGTCAGATGTCGCATTTGAAGAACCATATTAATCGAGTGCACGATGACAGTCGCCCAAAATTTGTTTGTGAtgtttgcaataaattatGTAATAGTCGTACTCATTTATCTTTTCATAAACGTAtacatgaaaattttaaaccaCATACGTGTAAAGTTTGCGATAAACGGTTTAGAGTTAAAGAACAATTGAAAGAGCATTCGAGAGTCCATACTGGTGAGAAACCGTATGTTTGTAATATTTGCGATAAAAGATTTACACAAAGGACACCGTTAAGGAGTCATCTAACAAACCGTATTGGCGACAAACCGACCATACAATTAATGACGAAACCTGATCAAATAGTGCAAAGGAAAAAACATACGTGTATGTACTGTTCAAAAAGTTTTCGTTGCAACTCTCGCTTAAAGGTGCACTTATTCATTCACACTGATGCTCGACCGTACTCTTGTGACGTATGTAAGAAAAGCTTCAAACGAATAGAACTGTTGTATTATCATAAATGTATTGACGATCCTGTTGAAAAAcacaaatgtgacatttgtggcagaAAACTTAGTAGTAAAAAGAGTTTAAAAAGTCATCGCTTACGCCACTTGAAGCAATTTAAAGTTGTTTGTGACACTTGTGGTCACGGTTGTATGTCACAGGCTGAACTTCGTGAACACGTGAACAGAACACATCTCAAAATAGATAAAGTCAGTCTTTGTAATATCTGTGGTCAGTCAATTAGTAAATCACATATGAAACGTCATATGAAAAGGCACGAAGAAGGCTATAATGACAAACGTAATTTCAAATGCGAATTCTGTACGAAAACTTATTTACAAATGTTTCATTTGAAGAAACATATTAAACGAGCACACGATGATACTCGCCAAAAATATGTTTGTGATGTTTGCAATAAAGAATATACAGATCGTTGTGGTTTAACCCTTCACAAACGTAAACATGAAAATATCAAACCACATGAATGTAAATTTTGCGATAAGAAATTCACAGTACCAGGACAATTAAAAGATCATCTTAGAGTGCATACAGGAGAGAGACCGTATGtgtgtaatatttgtgatagGGGATTTACACAAAGAACACCGTTAAGGATTCATTTGAGGCAACATACTGGCGAGAAGCCGTATTCGTGCGATATTTGTGATGCTAAATTTTCAGTCAAAAGTTATCTAACATCTCATTTGAAAGGGAAACACAATAAAGTTTAA
- Protein Sequence
- MKQHMKTHEEGYIEKRNFKCEFCTKAFRQMSHLKNHINRVHDDSRPKFVCDVCNKLCNSRTHLSFHKRIHENFKPHTCKVCDKRFRVKEQLKEHSRVHTGEKPYVCNICDKRFTQRTPLRSHLTNRIGDKPTIQLMTKPDQIVQRKKHTCMYCSKSFRCNSRLKVHLFIHTDARPYSCDVCKKSFKRIELLYYHKCIDDPVEKHKCDICGRKLSSKKSLKSHRLRHLKQFKVVCDTCGHGCMSQAELREHVNRTHLKIDKVSLCNICGQSISKSHMKRHMKRHEEGYNDKRNFKCEFCTKTYLQMFHLKKHIKRAHDDTRQKYVCDVCNKEYTDRCGLTLHKRKHENIKPHECKFCDKKFTVPGQLKDHLRVHTGERPYVCNICDRGFTQRTPLRIHLRQHTGEKPYSCDICDAKFSVKSYLTSHLKGKHNKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -