Mvar009021.1
Basic Information
- Insect
- Mylabris variabilis
- Gene Symbol
- ZNF236
- Assembly
- GCA_037464815.1
- Location
- JAZBGW010005526.1:1649-3820[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00061 0.037 14.5 2.4 1 23 113 135 113 135 0.98 2 12 0.0014 0.084 13.3 0.2 1 23 141 163 141 163 0.98 3 12 7.5e-05 0.0045 17.3 0.2 2 23 169 190 169 190 0.97 4 12 0.0014 0.083 13.3 0.2 1 23 196 218 196 218 0.99 5 12 0.0046 0.28 11.7 1.6 2 23 229 250 228 250 0.95 6 12 2.9e-05 0.0018 18.6 3.7 1 23 274 296 274 296 0.96 7 12 1.6e-05 0.00096 19.4 1.6 1 23 302 324 302 324 0.97 8 12 0.00099 0.059 13.8 1.8 1 23 330 353 330 353 0.95 9 12 0.00047 0.028 14.8 4.6 1 23 363 386 363 386 0.97 10 12 7.7e-08 4.6e-06 26.7 0.5 1 23 462 484 462 484 0.98 11 12 3e-05 0.0018 18.6 1.3 1 23 490 512 490 512 0.96 12 12 0.00036 0.021 15.2 0.2 1 21 518 538 518 538 0.96
Sequence Information
- Coding Sequence
- ATGGCACAAGAAGACCCAattactgataaattatcaacattgGTGACTTTACCGATACAAACCTACGATAATTCACCGGATAATCTACGTATAATCTCAGATGTTGTTATCAAACCGTTATCGGATACttctttttatattgttgatccaaatgatGCAACTAACAATGGGAATCTTGtacaacttttaaataataacaataacaataatttaatattgttgaatatacCAACAGATGAGCCGATTAATAATCGAAATGATACAGAATTGGTTAAATCGACATCATTAGATGTGATTGTTGAGAAAACTAATGATAATACTAAACCGATCACTATATACCGTTGTACTAGATGTGATGAAGAATtcaagaaatttaatttatataaaaagcaCATAATGTGGcataataatatgaaaaaattcaaatgtgataaatgttcaattagttataatattgaagagaatttaaatatacataGGGCTGTACATAATGATGGTAAACCAACTTGTCCAATATGTAAGATATCATTCCAAAGATTAGCCAGTTTAAAATCTCATCTAATTGTGCACCAAATTGAAGAATTGTACAAATGCGAAGAATGTCTATCAGAATTTGAACGAGAGgAGGAACTCGGTAAACATCTACAAACACATTTGAGTACGGCTAAAGAGAAAGACGGCACTGTATGTTCGTATTGTCGTGTAAAATTCACCGATTCCAATCTGTATAAAGAGCATATAGCACATCATGTGAAGGTGAAAAAGATGATATTACCAGGACGACGGGCACGAAGAAACCAACATAAACGTGAATACAATCATTGTTGCGGTGTTTGCCAGAAATCTTTCTCTAAAGCCTCACTATTGGAGCGTCATTCGCGTGTACATAGCGGCGAAAAACCGTTTATTTGTCATTATTGTAATCGTGGTTTTAACCAAAAAGGTGCTTTACAAATCCACGTAACCAAACATACCGGTATTAAACCGTACTGTTGTACATTATGTTCAGCTGAATTCTATCAGAAAGGTAATCTGCGTGTACATGTTGAAAAGACACATACAGCCCCATTGCCGGGCGTTCAAACGTATAAATGTTCGCATTGTCCGTGTATATTTAAGAAAGTGTCAAGTTTAAATGTTCATATAACAAAGACGCAtgttaataatcaaaatcaacCGAACAATATGAtcgatttaacaataaatagatcaaaatcaattgaaacgATCAATGATTGTGATAATagaggtaataataataataataataaacaagagaatggtaatgataatattaattatatacgTGTTGCTGAATCGTTTTCTGATGGTACAACACGTCGTTATTTAATCAAACAGAAACGTGTCAATAATACAcgaatttatatttgtaattattgtccGAAAGAATTTAAGAAACCATCAGATCTAATACGACATACACGGGTGCATACAAGAGAACGACCATTTTTGtgtaaatattgcaatattgcattttcgttaaaatcaaCGCTATTATCCCATTTGAAGACGCATTCAGGTAAATGCCATTATTCGTGTCCGGTTTGTATGAAGAAATTCTCAACGTCACGTGCtttaaatttacatataaagtaa
- Protein Sequence
- MAQEDPITDKLSTLVTLPIQTYDNSPDNLRIISDVVIKPLSDTSFYIVDPNDATNNGNLVQLLNNNNNNNLILLNIPTDEPINNRNDTELVKSTSLDVIVEKTNDNTKPITIYRCTRCDEEFKKFNLYKKHIMWHNNMKKFKCDKCSISYNIEENLNIHRAVHNDGKPTCPICKISFQRLASLKSHLIVHQIEELYKCEECLSEFEREEELGKHLQTHLSTAKEKDGTVCSYCRVKFTDSNLYKEHIAHHVKVKKMILPGRRARRNQHKREYNHCCGVCQKSFSKASLLERHSRVHSGEKPFICHYCNRGFNQKGALQIHVTKHTGIKPYCCTLCSAEFYQKGNLRVHVEKTHTAPLPGVQTYKCSHCPCIFKKVSSLNVHITKTHVNNQNQPNNMIDLTINRSKSIETINDCDNRGNNNNNNKQENGNDNINYIRVAESFSDGTTRRYLIKQKRVNNTRIYICNYCPKEFKKPSDLIRHTRVHTRERPFLCKYCNIAFSLKSTLLSHLKTHSGKCHYSCPVCMKKFSTSRALNLHIK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -