Mvar001600.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mylabris variabilis
Gene Symbol
-
Assembly
GCA_037464815.1
Location
JAZBGW010000342.1:16067-28274[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 60 0.00099 0.06 13.8 1.4 1 23 2 24 2 24 0.99
2 60 0.00041 0.025 15.0 1.1 1 23 30 53 30 53 0.94
3 60 4.7e-05 0.0028 18.0 2.4 3 23 59 79 58 79 0.99
4 60 0.00072 0.043 14.2 5.2 1 23 89 112 89 112 0.98
5 60 0.064 3.8 8.1 0.1 1 23 119 141 119 141 0.93
6 60 1.1e-06 6.8e-05 23.1 1.5 2 23 148 169 148 169 0.98
7 60 0.0021 0.13 12.8 4.1 3 23 177 197 175 197 0.97
8 60 1.2e-06 7e-05 23.0 3.7 1 23 214 236 214 236 0.99
9 60 4.6e-06 0.00028 21.1 1.1 1 23 240 263 240 263 0.97
10 60 1.8e-05 0.0011 19.2 0.2 3 23 273 293 272 293 0.99
11 60 4.4e-05 0.0026 18.1 1.1 1 23 303 326 303 326 0.97
12 60 0.041 2.4 8.7 1.5 1 23 333 355 333 355 0.97
13 60 5.9e-07 3.6e-05 23.9 0.6 2 23 362 383 362 383 0.97
14 60 3.4e-06 0.0002 21.6 2.4 1 23 389 411 389 411 0.98
15 60 1.2 71 4.1 2.6 2 23 438 458 437 458 0.91
16 60 0.004 0.24 11.9 2.7 1 20 464 483 464 485 0.92
17 60 6.1e-05 0.0036 17.6 2.8 1 23 490 512 490 512 0.99
18 60 0.0083 0.5 10.9 0.6 1 23 518 541 518 541 0.96
19 60 0.0062 0.37 11.3 3.6 1 23 588 611 588 611 0.97
20 60 0.0092 0.55 10.8 0.7 1 23 618 640 618 640 0.96
21 60 1.1e-05 0.00067 19.9 3.0 2 23 647 668 646 668 0.97
22 60 4.7e-07 2.8e-05 24.3 3.7 1 23 674 696 674 696 0.98
23 60 0.014 0.85 10.2 2.9 1 23 702 724 702 724 0.98
24 60 0.00055 0.033 14.6 1.4 1 23 734 757 734 757 0.98
25 60 0.00084 0.05 14.0 1.3 1 23 764 786 764 786 0.98
26 60 3.1e-06 0.00019 21.7 0.9 2 23 793 814 793 814 0.97
27 60 7e-06 0.00042 20.6 3.2 1 23 820 842 820 842 0.98
28 60 9.5e-06 0.00057 20.1 0.1 3 23 859 879 858 879 0.98
29 60 5.4e-06 0.00032 20.9 1.2 1 23 885 907 885 907 0.97
30 60 0.00016 0.0097 16.3 3.9 1 23 913 935 913 935 0.96
31 60 0.0014 0.085 13.3 0.2 3 23 943 964 941 964 0.90
32 60 0.00011 0.0065 16.8 0.4 3 23 970 990 969 990 0.99
33 60 0.00025 0.015 15.7 3.9 1 23 1000 1023 1000 1023 0.98
34 60 0.00099 0.059 13.8 0.2 1 23 1029 1051 1029 1051 0.98
35 60 5.9e-07 3.6e-05 23.9 0.6 1 23 1057 1079 1057 1079 0.99
36 60 1.6e-05 0.00094 19.5 0.9 1 23 1085 1107 1085 1107 0.98
37 60 9.3 5.6e+02 1.3 0.7 1 23 1124 1147 1124 1147 0.95
38 60 0.0053 0.32 11.5 4.8 1 23 1153 1175 1153 1175 0.97
39 60 4.1 2.4e+02 2.4 4.8 2 23 1177 1198 1176 1198 0.97
40 60 0.00082 0.049 14.1 0.6 1 23 1204 1227 1204 1227 0.97
41 60 0.015 0.92 10.1 2.6 1 23 1231 1253 1231 1253 0.98
42 60 7.5e-05 0.0045 17.3 3.5 1 23 1263 1286 1263 1286 0.98
43 60 0.17 10 6.7 1.1 1 23 1293 1315 1293 1315 0.89
44 60 1.5e-05 0.0009 19.5 0.6 2 23 1322 1343 1321 1343 0.97
45 60 8.7e-08 5.2e-06 26.6 0.7 1 23 1349 1371 1349 1371 0.98
46 60 0.28 17 6.1 0.9 1 23 1393 1416 1393 1416 0.97
47 60 0.00093 0.056 13.9 2.4 1 23 1422 1444 1422 1444 0.97
48 60 0.00078 0.046 14.1 0.6 1 23 1473 1496 1473 1496 0.96
49 60 0.00013 0.0077 16.6 3.4 1 23 1500 1522 1500 1522 0.98
50 60 4.6e-05 0.0027 18.0 3.1 1 23 1532 1555 1532 1555 0.98
51 60 0.32 19 5.9 0.5 1 23 1562 1584 1562 1584 0.89
52 60 1.3e-05 0.00079 19.7 0.6 2 23 1591 1612 1590 1612 0.97
53 60 6.2e-07 3.7e-05 23.9 2.1 1 23 1618 1640 1618 1640 0.98
54 60 0.0017 0.1 13.0 0.2 1 23 1669 1692 1669 1692 0.94
55 60 4.5e-05 0.0027 18.0 0.4 2 23 1697 1718 1696 1718 0.97
56 60 2.5e-05 0.0015 18.8 4.2 1 23 1728 1751 1728 1751 0.98
57 60 0.00049 0.029 14.8 0.6 1 23 1757 1779 1757 1779 0.97
58 60 9.1e-07 5.5e-05 23.4 2.0 2 23 1786 1807 1785 1807 0.97
59 60 5.8e-05 0.0035 17.7 1.1 1 23 1813 1835 1813 1835 0.95
60 60 0.18 11 6.7 1.8 1 23 1841 1864 1841 1864 0.97

Sequence Information

Coding Sequence
ATGTACGAATGTGATATATgccaaaagaaaatcaaattttatggTAATCTAATGTTGCACCGTCGGCGACATTtaaaagattacaattttagtTGTGAAATCTGTGGACAAGGTTTCATACAACAATGCGAATATAAAAGTCATATGGAGGGCAAACATAATAAATCGAATTTGTGTAATATTTGCGGTAGATCGTTCTATAATAAACATGGATTAGATTCGCATATGAAACGGCACGATGAAGATTACACTGGCAAACGTAATTTTAAATGcgatttttgtacaaaaaccTTTATGCAAATgatgcatttaaaaaaacatattaaTCGAATGCATAATGTTAATCGTCGTAAATTCGTTTGTGATCTATGTGGACAAGAATTGGCGAGTCGTGATGGTTTACGTTATCATAAATATGCCCATGAGGGTGTTAAGGAGAATGAGTGTACATTGTGTGGAAGGAAATTTAATCGTAAAAGTACACTAGTTGAACATATGCGTACACATTCCGGTGAAAAACCATATGGCTGTAAATATTGTTGTAGGACATTTTCACAACGTTCATCGTTGACAATTCATTTAAGACAACATACTGGAGAAAAACCATACACTTATATCCACCAATGCGTCTACGATAAATACAAATGTGATATTTGTGAAAAAACATTTAGTAAttcgttcaatttaaaatatcatcGCCGACGTCATTCAAAGAATTATCCTTGTGAGCATTGTGAAAAAGTTTTCACTACAGATGAcgaattaaaacaacatatgAGCAAAGAAcataaaacattaaattttatctcAACATTATGCGAGATTTGTGGTAAACCATTTTATGATCGTCGAGCCTTGGAATATCATATGAAACGACACGAGAATTTTGCACAAATGCAACACAGTTTCCCATGTGAAATTTGCAATAAGATTTTCTTTCgtaaaacgaatttattacagCATAATAAAACCGTCCATAATGATAATCGTCGGAAATTTGTTTGCGACCTTTGCGGTAAAGTCGTAGCAACTTTCCATACGTTACAATTCCACAAAAATACACATGAAGGAATCAAAACGAATGAATGTACAATTTGTGGTAAGAAATTCAACCGGAAGAGTACATTAGTTGATCATATCCGTATACATACTGGCGAAAGGCCTTACAGTTGTAATGTTTGCAATAAATCATTCGCACATCGATTCTCATTGATAACACATATGAGAGGACATACAGGAGAGAAGCCACATTCTTGTGTCATCTGTGGCGATAAATTCGTTACTAAAAAACGTACATTTATGAAACTTGATGAATGTCCGTGTTGTTTGAAACCTTGTAATCAAAAGAATTTAAAGGCGCATTTAATTACCCACAGTGATCAACGACCATTTTCATGTGATATGTGTGGTAAAGcatttaaacgaaaatatgAAAGGGATAGACATAAATgtgattttgataatagatATGAGTGTAATATTTGTCACAAAAAGCTCGCTAATGCTTACAATTTCGAGAATCATCGACGTCGCCATTTCAAagaatttcgatttaaatgTGGTCTTTGTGGACTTGGTTGTATGACAAATGCTGAATTGAAACAACATGTTGAAAGGACACATAATAAAACCAAAGTCAAAAAGAAGCCAGTTAAAACAACTCAtctttgtaatatttgtggtaTATCGTTGGCTGGTGGTACtacatcattaaaatttcatttgaaaCGCCACGAAGAGAATTATATAGAAAACCGTAGCTATGAATgtgaattttgtaaaaaattattcatgCAAGAATATCATTTAAAGTTGCATGTTAAACGGATGCATGATGATAATCGACCGaaatatatttgtaatttatgtgGTAAACAGGTAACAACGTTAAGTAGTTTACGTTTCCATAAAAATGTTCATAATGGTATTAAAATGAAAGAATGTAAAATATGTGGGAAGAAATTCAATCGTCATACCACCTTAGTTGTACATTTACGTACGCATTCCGGTGAGAAGCCGttcaaatgtaaattttgtgaCAAATCGTATTCACAGAGTTCATCATTGAAAATACACATGAGATACCATACAGGTGAGAAGCCGTATTGTTGTGAGGTTTGTGGTGAGCGACTAGTTAGCAAGGGTTTACTTACTTGCCATATGAGACGGCACGAAGAAAACTATACAGAAAAACGCAATTTTAAATGTGAATATTGTAAGAAAGCATTTTTACAAATTGGCTATTTACGTACCCATATACGAAGGATGCATAATGATAATCGGCGCCGTTTCACCTGCGATGTATGTGGTAAAGAATTAGCAAGTCGTCATAGTTTCCAGTTGCATAGGAATGTGCATGAAGGCATTAAAACGAACGAGTGTGAATTGTGTGGTAGACGATTTAATAGGAAGAGTACTCTAGTCGAACATTTACGTACACATTCTGGCGAGAGACCGTatacttgtaaatattgtGATAAATCGTTCTCTCAAAGATCACCGATGGTGATCCATATGAGACACCATACGGGCGAACATCCGTGCGTTAAGAAAGAGTTTGAAAAAATTCTGTTATGTCCAGTTTGTCCGAAAATGTTTGCTTACAACTCACAGTTACAAAGACATTTGTATGTTCACACTAATCAACGTCCATATTCGTGTAAACAATGTGGAATGAAATTCAAACAGAAAGCAAATTTAAAAGCACACAGCGCCACACATGACAAAACTGTATTGCATAACTGTACGATTTGTCCgaaaacatttaaaactaCTAACGCTTTGAAAGCTCACCTTCAGCACCACtcgaaaaattacaatatattCTGTGATATATGTGGACGTGGTTTTGTCTCTAACAGTACATATCGAGTTCATAAATCCGATGTTCATGAACGATCTAATCTTTGTAATGTTTGTGGCGAATCGTTGAGTAGTAAATCGGCATTGAAATTGCATTTAAAACGACACGAAGAAAATTATACAGAAAAGCGTAATTTTAAATGCGAATTTTGTCCGAAGAAATTCATGCAACAATTACATTTAAGACAACATATACAACGTATGCACGAGAATCGTCCAAAGTATGTGTGTGATTTTTGTGGTAAAGAAATTACTAGTTTAGCTAGTCTAAAATCCCACAAAAACATACATAATGGGATCAAATCATTTGAATGTAATCTATGTGGAAGGAAGTTTGTTAATCGAAAATCGTTAATAGTACATATCCGAACGCATTCTGGTGAAAAACCGTACagttgtaaattttgtaataaatcatttgCACAACAATCACCATTGATAATACATACCAGATTACATACAGGAGAGAAACCATACGCTTGtgatatttgtcaaaATAAAAAGAGTTACAAATGCATTTATTGTGAAAATGTCTACCAAATTAAATGGTATTGGCAACAGCATATGATCAGAAAGCATGAAGAACATCGGCCACATTCGTGTTTAATTTGCCATGAAAGATTTAAACGCCTAGAAGAATACACAGTACATAGAAAAAGTCACAAACAGTGTagtatttgtcaaaaaaagcTTAAAGGCTTCTTCAATTTATATTGCCATATTCGTAAGCATTCTGAAAATGCCAAATTTTTTTGTGATGTTTGTGGCAGGGGTTATGTGTTAGAATCTCAACTCAGACAACATAAAAAAACTAGTCATGGAGTTCCTCATGTTTGTGATATTTGTGGTGTATGCCTTAAGATTAAATATAGTTTTGACGAGCATATGAAAACACACGAAGAAGATTATAAAGctaaatgttattttaaatgtgaatTTTGTTCACGTACTTTCACACGGGAACGTTATTTGTCTCGCCATATTCAACGTAATCATAGTGAAAATCGAAAGAAGCACATGTGTGATTTATGTGGGAAAACTTTAGCGACTAAGAAGGGATTAATGTTCCATAAAAATGCCCATAAAGGTATTAAAACGGTTGAATGTCAATATTGTGGTCGAAAATTCAATCGTGAAAACACTTTAGTCGATCACCTACGAACACATACTGGTGAACAACCATTTAAATGTACTTATTGTGGTAAAGCTTTTTCTCAACGATCTGCCTTGCAGATTCATGTGCGGTTGCACACTGGCGAACGGCCATATTCTTGTGATATTTGCCAAAATAAGATggaaatagataaaaagagTTACAAATGTCTTTATTGTGAGAACAGTTATCAGATTAAATGGTATTGGCAACAGCATATGATCAAAATGCACGAGGAACACCGACCGCATTCGTGTTTAATTTGTGATGAGAAATTTAAACGCCTAGAAGAATACACGATACATAGAAAAAGTCATAAACAGTGTAGTATTTGTCAAAAACATCTCAAAGGCTTCTTCAATTTATATTGCCATATTCGTAAACATTCTGACAATGCTAATTTCTTTTGTGATGTATGTGGAAAGGGTTATGTATTAGAATCTCAACTAAGACAGCATAAGAAAAGTAGTCATGGAGATCCCCATGTTTGTGATATTTGTGGTATATGTTTTAAGGTTAAGTACAGCTTTGATGAGCATATGAAAACACATGAAGAAGATTACAAGgaaaaatggaattttaaatgTGAATTTTGTTCACGTGCTTTCACACAAAAACGATATTTGTCTCGCCATATTCAACGTAGTCATAGTGAAAATAGAAAGAAGCATGTCTGTGATTTATGTGGGAGAACTTTAGCATCTAAGAAGGGATTAATATTCCATAAAAATGCTCATAAAGGTATTAAAACGGTTGAATGTAAATATTGTGGTCGAAAATTCAATCGTGACGACACTTTAGTGGATCATTTACGGACACATACTGGCGAACAACCATTCAGATGTACCCATTGTGACAAAGCGTTTTCTCAGCGGTCTGCTTTGCGAATTCATGTACGTTTGCATACTGGGGAACGACCATATTCATGtgatatttgtcaaaataagTTTGTTTTATACCATACACGCAGACATTCTGATGATGTTAAATTCTGTTGTGATATTTGTGGAAAGGGATTTATTGTGGAAGTTGGCCTTAGAGCGCATAAGAAAGCAGTTCATGGTGCCCTTCTCGTTTGCGAGATTTGTGGTAcatcgattaaaaataaaaatatgtttgAAAATCATATGAGAACACATGAAAAAGATTACAATGAGAAACGGGATTTTAAATGTGAAGTTTGTTCACGTGCTTTCAGACAGAAAAGACATTTGTATCGTCATATTCAACGTAGTCATGAAAAACGGATGCAGCACGTATGTGATTTATgtggcaaaattttatcaagtaAAAGAAGTTTAGAGATACACAAAAATGTTCATGAAGGTATTAAGCCAATTGAGTGCAAATATTGTGGTAGAAAATTTACACGTCGTACTACATTAACAGATCATTTACGGACACATACGGGCGAACAACCTTTCAGCTGTATCCACTGTGACAAAGCCTTTTCTCAACGGTCTGCTTTACAAATTCATGTACGGTTGCATACTGGCGAACGGCCATATTCTTGTGATGTTTGCCAAAATAAGTTCGTCTGTAAGGGTGCATTATCAGTtcatatgaaaaataaacataagaCCGTTtga
Protein Sequence
MYECDICQKKIKFYGNLMLHRRRHLKDYNFSCEICGQGFIQQCEYKSHMEGKHNKSNLCNICGRSFYNKHGLDSHMKRHDEDYTGKRNFKCDFCTKTFMQMMHLKKHINRMHNVNRRKFVCDLCGQELASRDGLRYHKYAHEGVKENECTLCGRKFNRKSTLVEHMRTHSGEKPYGCKYCCRTFSQRSSLTIHLRQHTGEKPYTYIHQCVYDKYKCDICEKTFSNSFNLKYHRRRHSKNYPCEHCEKVFTTDDELKQHMSKEHKTLNFISTLCEICGKPFYDRRALEYHMKRHENFAQMQHSFPCEICNKIFFRKTNLLQHNKTVHNDNRRKFVCDLCGKVVATFHTLQFHKNTHEGIKTNECTICGKKFNRKSTLVDHIRIHTGERPYSCNVCNKSFAHRFSLITHMRGHTGEKPHSCVICGDKFVTKKRTFMKLDECPCCLKPCNQKNLKAHLITHSDQRPFSCDMCGKAFKRKYERDRHKCDFDNRYECNICHKKLANAYNFENHRRRHFKEFRFKCGLCGLGCMTNAELKQHVERTHNKTKVKKKPVKTTHLCNICGISLAGGTTSLKFHLKRHEENYIENRSYECEFCKKLFMQEYHLKLHVKRMHDDNRPKYICNLCGKQVTTLSSLRFHKNVHNGIKMKECKICGKKFNRHTTLVVHLRTHSGEKPFKCKFCDKSYSQSSSLKIHMRYHTGEKPYCCEVCGERLVSKGLLTCHMRRHEENYTEKRNFKCEYCKKAFLQIGYLRTHIRRMHNDNRRRFTCDVCGKELASRHSFQLHRNVHEGIKTNECELCGRRFNRKSTLVEHLRTHSGERPYTCKYCDKSFSQRSPMVIHMRHHTGEHPCVKKEFEKILLCPVCPKMFAYNSQLQRHLYVHTNQRPYSCKQCGMKFKQKANLKAHSATHDKTVLHNCTICPKTFKTTNALKAHLQHHSKNYNIFCDICGRGFVSNSTYRVHKSDVHERSNLCNVCGESLSSKSALKLHLKRHEENYTEKRNFKCEFCPKKFMQQLHLRQHIQRMHENRPKYVCDFCGKEITSLASLKSHKNIHNGIKSFECNLCGRKFVNRKSLIVHIRTHSGEKPYSCKFCNKSFAQQSPLIIHTRLHTGEKPYACDICQNKKSYKCIYCENVYQIKWYWQQHMIRKHEEHRPHSCLICHERFKRLEEYTVHRKSHKQCSICQKKLKGFFNLYCHIRKHSENAKFFCDVCGRGYVLESQLRQHKKTSHGVPHVCDICGVCLKIKYSFDEHMKTHEEDYKAKCYFKCEFCSRTFTRERYLSRHIQRNHSENRKKHMCDLCGKTLATKKGLMFHKNAHKGIKTVECQYCGRKFNRENTLVDHLRTHTGEQPFKCTYCGKAFSQRSALQIHVRLHTGERPYSCDICQNKMEIDKKSYKCLYCENSYQIKWYWQQHMIKMHEEHRPHSCLICDEKFKRLEEYTIHRKSHKQCSICQKHLKGFFNLYCHIRKHSDNANFFCDVCGKGYVLESQLRQHKKSSHGDPHVCDICGICFKVKYSFDEHMKTHEEDYKEKWNFKCEFCSRAFTQKRYLSRHIQRSHSENRKKHVCDLCGRTLASKKGLIFHKNAHKGIKTVECKYCGRKFNRDDTLVDHLRTHTGEQPFRCTHCDKAFSQRSALRIHVRLHTGERPYSCDICQNKFVLYHTRRHSDDVKFCCDICGKGFIVEVGLRAHKKAVHGALLVCEICGTSIKNKNMFENHMRTHEKDYNEKRDFKCEVCSRAFRQKRHLYRHIQRSHEKRMQHVCDLCGKILSSKRSLEIHKNVHEGIKPIECKYCGRKFTRRTTLTDHLRTHTGEQPFSCIHCDKAFSQRSALQIHVRLHTGERPYSCDVCQNKFVCKGALSVHMKNKHKTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-