Mmin011540.2
Basic Information
- Insect
- Mycalesis mineus
- Gene Symbol
- zfh1
- Assembly
- GCA_034621355.1
- Location
- CM067892.1:44104-54697[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.0044 0.3 12.3 1.7 1 23 79 101 79 101 0.95 2 8 3.9e-06 0.00027 21.9 0.8 1 23 112 134 112 134 0.98 3 8 5.6e-05 0.0038 18.3 6.4 1 23 143 165 143 165 0.98 4 8 0.00016 0.011 16.9 1.0 1 21 171 191 171 192 0.95 5 8 0.01 0.69 11.2 0.2 2 21 457 476 456 477 0.92 6 8 1.2e-05 0.00082 20.4 1.1 1 23 773 795 773 795 0.94 7 8 4.1e-05 0.0028 18.7 7.6 1 23 801 823 801 823 0.98 8 8 0.056 3.9 8.8 7.0 1 21 829 849 829 850 0.96
Sequence Information
- Coding Sequence
- ATGAAAGTGCATAGCCAGCTTATGGGAGTCGGCGGATGGTACGAGTGGCTGGCGGCCGACTGGCTGGCCGACATGCGGAGTAAGCAGGTGCCCACTTCCACCACCTCGGCCAGGCTGGCGGCCTTGATCCGACCgctgggcggcgcgggcggtgGCGCAGGGGGCGCGGAGAGCAAGCCGGCCGAGGAAGAGGAGGAGGACCGCTCAGGCTCGCCGCTGGGCCCCGGCGGGCCCTACACGTGCAGCCACTGCCGCGGCACCTACCCCACACGCGAGCAGCTGGAGCGCCACGAGACGCTGCATGCGCCCAGCACTCAGGTGGATAACGTCAAATATTCGTGCAAGATATGTCCGAAGAGCTTCGATAACGTGTACCGTCTGCAGCGGCACATGATCAGCCACATCGACTGCGCGTCGATACGCAAGTACAAGTGCAACGACTGCGAAAAAGCCTTCAAGTTCAAACATCACCTCAAAGAACATAATCGAATACACAGCGGCGAGAAGCCGTTCGAGTGCGCCAACTGTGGGAAGAAGTTTTCACATTCCGGCTCGTACTCCTCGCACATGACCTCTAAGAAGTGTCTCGTTATGAACCTCAAGATGGGGAGGATAAAGCCTAACAACCCTGCACTCAACCCAGACCGAAACTCATCACGCAAACGAACACATGCCTTGGTAGCATCGCAGCTGAATAACAACGTAGCCCCGAACAACCCCTCGTTTTTGCCGATATTACCTAAATACAATGAGGCCGCCGCTGCATTTTTTGCATCGATGTCGCCGCAAGAAAATAATTTCCATCGACCGCCCGTGGGACAACCGGGAATGAATCCTTTCTACATGCCACCTGGCATGCCCATGAGTCCCGCTAGCGGTATAGCCCCTTACACCTTTCCCGCTTCGTTGAGCCAACTATTTGAGCAGCTAGCCTCACAACAGTACCAACAGAGAAAAATGGAAACTCCGAGTCCGAAACGAGTGAGTCCACTCGGTCCAAACCCTGAAGATTTAATAGAAGAAGTTACTGAGGAAGAAGATAAAAGATCCGAAGGCAGCGCCGAGTTAGTGATGGATATCGAAGACGATGACAATGTTTCAATCAAAAAGGAGCAAGACGACCGAGACAGCGAACAAATATTACGATCTCGCGTCTACGATTCCGTCCCAactaatgatgacaatggagcTGAAAGTGATCAGTCAGGTTTCAACACCATTTTAAAATCTGTAAATGCTTCTGTAACCAAACACTTTTTTAGAGCAAATATGGAAAGTCTATCACCAGCCTCGGGTAAAGTATGCCCTACTGTAGAGTCGCCCCCTGCACCCCATCTAACAGTGAAAGAGGAACCAGAGGATCCACAGGTCTGCTTAAAGTGTAATCTTTCATTCAGTGACAAAAATGACCTTGTCGAGCATGAAAAATTATGCGGAAACATGTTCAGAAAACATGAAGGTCTGGCAGCTCAAATGGCTGAAACGGTAGCTCTTAACAGATTGGAAGCTGAAATGCGGGCGTCGATACAGAGTGGAGTAAGTGCAAGCGAAGACGAAGACTATGGAAAAGATGACATCGAAGATAAAGTGTCCTTGCACGATGGTGACCGAAAAATCCGAGTGCGTACGGCGTTGAGTGAGGAACAACAAACCGTATTAAAAGAGCACTACGCCATAAATCCTCGTCCAAATCGtgaggaatttaaaaaaatagctcAACAAATCGGCCTAGACAACAGGGTCGTACAAGTATGGTTTCAAAACAATAGAGCAAGGGTAAGGAGAATGACGCAAGTGGTTCCAATGCCCGACCAACCTCTAGATCTATCCACAAAAAAGTGTAGTGCGTCCGTCACATCGAGTCCGGCGCCGTCGCCGCCCTGCAGCATTTCAGTTACACATTCCGATTCCGAAGAAGCCGTTAATTTAAGTCAAAAATCTTCGCGGAGCACCACGCCGCACCGCTCTCATTATTTAAACACCTACCCACATTCCAATTGTTCTTCCTCATCGTTTATCGATTTTAGATTGTCGCCTTCGCCGGGCGAAAATATAAATGGACAGAAAAGGCTAATGTCTCAAAAGATGCCTGTCAACCCTGTGATGCCGATGGACAAGTTACTCCAGTACAACGACATGACGAACGGACGGTCGCCGATTCTCAACATGCACATGTCGGAGAACAGGCACGAGTCCAGTCCGTCTTACGATCGGCCCACATGGAGCGATGGCCTACATTCGCAGAACGATTACGACGACGAACCAGTACTTAAAAAAAGCAAACTAAAAAGTGACTACAAGGAGGGAGAGGGACAGTTCGTGTGCGACCAGTGCGACAAAACATTCGTCAAACAGAGCTCCCTCGCGAGGCACAAATACGAACACTCAGGACAACGTCCCTACAAGTGCGCAGAATGCGACAAAGCCTTCAAACACAAGCACCACCTCACGGAGCACAAGCGGCTGCACACGGGCGAGAAACCCTACCAGTGCTGCAAGTGCCTCAAGAAGTTCTCGCACTCCGGCTCCTACAGCCAGCACATGAACCACAGGTTCGCCATCTGCAAGCCCTACAGAGACTAA
- Protein Sequence
- MKVHSQLMGVGGWYEWLAADWLADMRSKQVPTSTTSARLAALIRPLGGAGGGAGGAESKPAEEEEEDRSGSPLGPGGPYTCSHCRGTYPTREQLERHETLHAPSTQVDNVKYSCKICPKSFDNVYRLQRHMISHIDCASIRKYKCNDCEKAFKFKHHLKEHNRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRNSSRKRTHALVASQLNNNVAPNNPSFLPILPKYNEAAAAFFASMSPQENNFHRPPVGQPGMNPFYMPPGMPMSPASGIAPYTFPASLSQLFEQLASQQYQQRKMETPSPKRVSPLGPNPEDLIEEVTEEEDKRSEGSAELVMDIEDDDNVSIKKEQDDRDSEQILRSRVYDSVPTNDDNGAESDQSGFNTILKSVNASVTKHFFRANMESLSPASGKVCPTVESPPAPHLTVKEEPEDPQVCLKCNLSFSDKNDLVEHEKLCGNMFRKHEGLAAQMAETVALNRLEAEMRASIQSGVSASEDEDYGKDDIEDKVSLHDGDRKIRVRTALSEEQQTVLKEHYAINPRPNREEFKKIAQQIGLDNRVVQVWFQNNRARVRRMTQVVPMPDQPLDLSTKKCSASVTSSPAPSPPCSISVTHSDSEEAVNLSQKSSRSTTPHRSHYLNTYPHSNCSSSSFIDFRLSPSPGENINGQKRLMSQKMPVNPVMPMDKLLQYNDMTNGRSPILNMHMSENRHESSPSYDRPTWSDGLHSQNDYDDEPVLKKSKLKSDYKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCAECDKAFKHKHHLTEHKRLHTGEKPYQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00205017;
- 90% Identity
- iTF_01021077; iTF_01151125; iTF_01151533; iTF_00205017; iTF_00205485;
- 80% Identity
- iTF_01021077;