Basic Information

Insect: Musotima nitidalis
Gene Symbol: MBD-R2
Assembly: GCA_949126915.1
Location: OX421440.1:3039160-3065672[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 4.1 3.7e+02 2.7 0.5 1 23 325 347 325 347 0.92

2 10 0.028 2.6 9.5 0.9 1 23 354 377 354 377 0.93

3 10 0.41 36 5.9 0.2 1 23 381 403 381 403 0.92

4 10 0.011 1 10.8 0.8 1 23 408 431 408 431 0.97

5 10 0.0014 0.13 13.7 0.7 1 23 435 458 435 458 0.97

6 10 0.089 8 8.0 0.3 2 23 547 569 546 569 0.96

7 10 0.01 0.9 11.0 0.5 2 20 585 603 584 606 0.92

8 10 2e-05 0.0018 19.4 2.5 1 23 612 634 612 634 0.99

9 10 0.00013 0.011 16.9 2.7 1 23 641 663 641 663 0.98

10 10 0.00012 0.011 17.0 2.2 1 23 669 692 669 692 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	4.1	3.7e+02	2.7	0.5	1	23	325	347	325	347	0.92
2	10	0.028	2.6	9.5	0.9	1	23	354	377	354	377	0.93
3	10	0.41	36	5.9	0.2	1	23	381	403	381	403	0.92
4	10	0.011	1	10.8	0.8	1	23	408	431	408	431	0.97
5	10	0.0014	0.13	13.7	0.7	1	23	435	458	435	458	0.97
6	10	0.089	8	8.0	0.3	2	23	547	569	546	569	0.96
7	10	0.01	0.9	11.0	0.5	2	20	585	603	584	606	0.92
8	10	2e-05	0.0018	19.4	2.5	1	23	612	634	612	634	0.99
9	10	0.00013	0.011	16.9	2.7	1	23	641	663	641	663	0.98
10	10	0.00012	0.011	17.0	2.2	1	23	669	692	669	692	0.93

Sequence Information

Coding Sequence: atgcgCTGTATCGTAGAAAAGTGCAATAATGTATCAAGAAGAAACCAATTTGACGAAATCAGTTTTCATTTATTCCCACTAGATCCTGTCCTCAGACAGGATTGGTTATGCTCTTTAGGTATGGACGATGCAGAGGTTAAAGGCACAAGCTCTATTTGCTCCAGCCACTTTAACGATGAAGACTTTTGTGAAGCCCAGGGCGGGGACAAGAAGCTGAAAAATGGTGCTGTACCTGTAATTGGTGTTTGGACTGAGCAAGTCGACCTGCCCCAATGTTTCTGCTGGGAGTGCGCTGGTAGACTTCTGTCGAGCTATAAGCTGTTCAAGAAGGCTTTGAGCAGTCACAAAGCTATTTTGGAGCTGCTTAAAGACACTAGACATATTAGACTAAAAGACATATTGACAATAAACAGAGGCACAAGTTCTttgcaaaaacattttatacaagAAAAAGATTACTATATATTCGAAGAAGATTTATCTCATAATAATCTAGCTGACAATCAAGAACAATTAATTAAAGAAGAATACGGAGACAAGACCATTGGAGAACCATTACAAGTGCTAGAAGATAATTTACCAGATTTAGAAACTATAGATGTGAAAGATGAGTCGGGAGTTGATTTTTTTGACGAATTTGACAATTTCAATGACTCCGATGACAATGTAAAACTTAGTGAAGTTGCCAATCCGGAAGTGGAAAGTAAACCAAAGTGTAAAGtgaaaaagaaaaagttgaAAGTGGAGAAAATTGTGAAAGTGAAAGTGGTTAAGGAGAAGAAAAAGAGAGACAAGGAAGAGGAAGATAATCCAATGTCAACTAttgataaaTACAAAACATCAGATGTAAAAAGACGAAAAACTAATGAAGGACCCGATGATTCTCTATTTATTATAAGCAATTTGTCATACGAAGAACAGATAGCAGACATATATAAAAGACAGGATACAACAGCATATAAGAACGCTCCGTATAAATGTACAGCTTGTTTTAGAGGATTTCAAATACAGGAGAGATATGACGCTCACATCGTGAGGCATAGTGATCAAAGCGGTTCCTAcgaatgttttatttgtaaaactcGTCTCAAGACAGGCAGGGCTCTAAGGAAACATCTGACGGGCCAACACACGGAGAAATTCAGCTGTAAGGGTTGCCCTTTCGTCACAAGAAATAGAGGTGTAGCTAGAGAGCACGAGAAATGGCATGCGGGAACCAAATATCAGTGCCCACACTGTCCGAGCGAATTTGATAAAGTGACTACTTATATGGGACATATACGGATAAAACACGTGTCCGATTTCGTGTGTGAATTGTGTGGATTTACATTTGTCAGTAAAAAGGGGATTGAAGtgcataaaaagaaaaaacataggcTCTCTGATAAAAACgtTAACTTAGAAGGACCGTACTGTTGTGTATGTGATGTAACATTTCTATCTGAAGAAGCTCACAGTAGGCACTTAAAACTATCATCGAGGCATAGCAGTGACAATGATCCTAATCGCATAAGAAATGACTCCCAAAGTCTACACACGGAGAGGCATGGTCGTGTGGTGAGGCGGATCGAGAGAAGACCAGTGATTCACCCTCGGGATCCCGCTGACAGAACGCGGGGAGCAGAGCCTGGCCCGGTCACTTGTGAACAGTGTGGCATGCAGTTACGCGATTTGCGCCTCTACGCCCAACACTTTAGGAGGGCCCACCCGGACAAGAATAGGACCAAGTACCCGGCTATGAAAACTCCTTGTATGTGCGAGCAGTGCGGGAGAATATTTCAGaGCATGGCTCTCCTGAAAGACCACATGTGGGTCCACACGGGCGAGAAACGGTTCAAATGCGACCGCTGCGAGAAAAGCTTCACCCAGAAAACGAACCTGGTGTTCCACATGAGGGTCCACAGCGCGGCGCGGCCCACGTACGAGTGTCCGCTGTGCGGGAAGCACTTCGCCTTTTACAACAACCGGCGCAGACACATGTTTatCCATACCGGCCTCAAACCCTTCAAGTGCGACACGTGCGGGAAGTGCTTCACCACAGCGGGCGAGCAACGTGCGCACGTCGAGCACGTTCACATGAAGAAACCCTGGCCCAAGCGCGCCCGCACGCGGCAGCAGGACTGGCATAAGTGCGCCGTGGACGGGGCTGAAGATTGA
Protein Sequence: MRCIVEKCNNVSRRNQFDEISFHLFPLDPVLRQDWLCSLGMDDAEVKGTSSICSSHFNDEDFCEAQGGDKKLKNGAVPVIGVWTEQVDLPQCFCWECAGRLLSSYKLFKKALSSHKAILELLKDTRHIRLKDILTINRGTSSLQKHFIQEKDYYIFEEDLSHNNLADNQEQLIKEEYGDKTIGEPLQVLEDNLPDLETIDVKDESGVDFFDEFDNFNDSDDNVKLSEVANPEVESKPKCKVKKKKLKVEKIVKVKVVKEKKKRDKEEEDNPMSTIDKYKTSDVKRRKTNEGPDDSLFIISNLSYEEQIADIYKRQDTTAYKNAPYKCTACFRGFQIQERYDAHIVRHSDQSGSYECFICKTRLKTGRALRKHLTGQHTEKFSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCPSEFDKVTTYMGHIRIKHVSDFVCELCGFTFVSKKGIEVHKKKKHRLSDKNVNLEGPYCCVCDVTFLSEEAHSRHLKLSSRHSSDNDPNRIRNDSQSLHTERHGRVVRRIERRPVIHPRDPADRTRGAEPGPVTCEQCGMQLRDLRLYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGRIFQSMALLKDHMWVHTGEKRFKCDRCEKSFTQKTNLVFHMRVHSAARPTYECPLCGKHFAFYNNRRRHMFIHTGLKPFKCDTCGKCFTTAGEQRAHVEHVHMKKPWPKRARTRQQDWHKCAVDGAED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01020377;
90% Identity: iTF_01020377;
80% Identity: iTF_01020377;