Mdom008466.1
Basic Information
- Insect
- Musca domestica
- Gene Symbol
- -
- Assembly
- GCA_000371365.1
- Location
- Scaffold19699:92432-97501[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0029 0.15 12.3 0.1 2 23 246 268 245 268 0.96 2 9 3.3 1.6e+02 2.7 3.1 2 21 1050 1071 1049 1073 0.92 3 9 1.3 63 4.0 0.5 3 20 1088 1106 1087 1110 0.92 4 9 1.9e-07 9.7e-06 25.5 2.2 1 23 1146 1168 1146 1168 0.98 5 9 0.037 1.8 8.8 7.5 1 19 1190 1208 1190 1210 0.97 6 9 0.00038 0.019 15.1 0.5 2 23 1219 1240 1218 1240 0.98 7 9 0.02 0.98 9.7 3.3 1 23 1246 1268 1246 1268 0.97 8 9 0.14 7.1 7.0 3.6 1 23 1274 1297 1274 1297 0.96 9 9 0.0018 0.089 13.0 4.8 1 23 1306 1328 1306 1329 0.95
Sequence Information
- Coding Sequence
- ATGAATGATGCTAATTATTCAATGTACGACAGCTATTTTTGTATTTCGAACTACCAGCCGTCATCCATTGATAGTTCCTTAGTTGACTATGATGCCCAAACAACAAGTCATTATTCCAACAACTGTGAATTACTGTCCACAACACCAGCTGTAGAGCAGAGGCATCATGGAGgtcaaaccaatattttcccCTATCTTTCACACACGAGGGATGAACCTAACAAAATTGCAGATACTGCCACGAATTTATGTGTGTCCAACACCTCGGCAGTGCCTGCAGGCCCGGCACCGACCACTTTTGTAAATATACCATTTGTACAGATCCACACCACAGATGTCCAACCACAACGTACAAGTTACGGCAATGTGTTTCGTAGAAATATAAGTCGCCAAGAAGAGATTAAATCAGAACCAATTAAATCAGAAGGTTCTGATTCTTCTAAAGAAAGAACGAATGCTACTCCAACTCCACCAAGGGCGCCTTCGGCAacgcaaaaaaatcaaaacgctGAGGATAATGCACAAAATCAAAACGAACTTGTTGGAGAACGAGTCGAAAATATTAATGAGCAGGAAAATCAACACAAAGAAGAGGATCAGTTAATAAACCAAGCTTCATGCCAAGTTTATAAATGCTCGCTATGCCCCTTTATAAGTTTAAGTGACAATCAGAGATACGAACATGAAAAATCTCGACATGCCGATAAACAAAAGGAAGCCCTCCGGCAAGAGTTGAAGTGTCCaggaTGTACTAATGTTTTCTATATACAAGAATCACTTGAAACCCATTTGCGACTGGATCACATCATGCCAAAAGATGAGGCACTTAAATTAGCTCACTCCATTGTTCAAGCTAACAGCAAAGACACTCAACAATCAACGAAAGGATTATCCGGTGATTCAATACAAAGTGAACCGCAGAGAAAAAGTcgcatttatttgaaaaatgttgaatgtcTAAGGGAACCAAATCGTCAACCAATTGAACAAACTGAAAATcaattatttggaaattgtagcaacaataacagcagcaaTGCCAGTCTGCATcaaaatcaaaaggcaccaaaacaaaaaatttccataaaaagcgTTGATGTGTTGCGAGAGCCTGCATTATTGAGACGGGATTATGGCATGGATAATACTAATTATAGTATTTTTTCAGCAGATAACACAGACAATCAACAGCACGGAGAGACTGTATCAAACGCAACAGATCCTGCTTCTTTTAATGACAACCAAAATGACATGATCTCCATGAGTAGGAACCAAAGCAATGGAGACTGCGATAAAACGAGAAAACCCAAAATTTATGTTAAAAGTGTTGAAAGTTTTAATTTAATGCCTCTGGAATACATTGAAAGTCAATCGAATATATTTAACAATGCTACACAACCCTTTGACTCGAACTCCGCACACATACCTTTTATATATGAAACGAATACCAATATACCAATTTCAACAAGTAATGTTAGTGGGTCCTACGGTCATAATGATATGACCAACAACGCCTATCAAATAGATATAAATTCATCATCAAATGATAATAACTACATACTGGATAATAATCCATTATATCTAGTCAATGTTGACAATATGGGAATAAATAATTGTGGAGGCCAGGTAGAAAGTGTTACACTTATAACTGACCCTACTCCTCCACCAGATTCATCTGCAGTAAATTTGGAAGAACCTATAAATACAGCGAATAACAACTTTCCTCCAGCACCCCCAGAACCCCAACGCGGAACATTGCATTTGCGTACTGTTGACGAATTGAATTTAATGAATGAAAACGAATTCCAACATCCAACCAACGCTGATATAAGTCAAATGaGTAAAAATTCAACAAACTCGGAGCAAAGGGGCACATTGCATTTACGAACAGTTGACGAACTAAACCTGATGAACGAAAATGAAGTACAACACCTAATAGCTCCCAATTTGGATAATAATCACAGTACCGAAGGACTAGACAATAACATAAATATGAATGATGATAATCTAATTGGTCATGGTATTTATGACGATTCTGATGCTTTTAAGTTTCAAGATTTGGACagtcaaatggccaatgaatgGCCCGAAACATACGATGATTTGGCCGAGGACATTAATGGCATAATAACTGAGGCTACCAATAATCCGgtaacaaacaacaataacaatagagAGGGGCATGTTGTCTTGAATTCGACGGGAGATAATCAAAAGACCTTTTCCAGCAGCATGGAAGTGGATAATCCTCAAATGTCTTTAATTACAATCAGAGACATAGAAGAACTGACGGGAGGAACGAGTTATATTCATGACATGGTACACGATACTAATTATGCAAATGATAATACTTCAGATGTAACTTCTTCTATTGCCAATATTTCGGAGCAAATAGATAACTCTGTTGTTGCAAAAGGCAATTGTGGCACATCAGAAGATGCAGAAAATCTTAAACGTGAATTGAGTAATGCAACACCGGAGACAAAAGATTCTACAACATTAGGAAATGAATGCGAATCCAATATACCCATTATACGTGTGGAATTGCATAAAGAAGTTCCTGTCACGACAGAGCCCCGTTCTCCTATATTGACAGCATTAAGTGTATGTGAAATAAATGCACGAAGTCCAAAAATATCATCTACATTAAACAAAAACTCCGATTGCAATATAATTTCCAGTAACGAACTAAACAGCATAACTCAGAATTCTATCGTGGATCGAGTACCTCATTCTCCAATACATATTCCTAACGAGAGTAGtgataacaattttattaaaacatcaACGTCCTCTGTAACTTCTAAGAACGTCAATACAATAACACCTCTCTTAGCAACGGTCACACACATGTCAACATCGCAATCCTCAGCCACAACATCATCAAATGACATTCCAATACCGCCTTTAGTGCCGGTTACAGATTCAATTATGATTAACAGGGAAATTTCTTCAGAATCTGATTCAGCTGTGCCTAAGGACAAATTTCCTCCCGCCCAAGAAACTCCTGCAGAAAAGGGTCGTATATATGTTGCAAATAATTTAATGGAACCACCCAAGAAACCTGTTAGCGTTCGCGGTAGACCATTTGGATCTAATCGTACCAGAATGGCCTTGGAATCCACATCAACAAATGATGTATTTGTAAAATGTAGCTTTAAAGGTTGTGCTTTTCGGTTTAAAAAGAACGAAACTTTGGAATATCACATAAAATGCCATGACATTGACCCAGCCAATGTGAATAGCAATCAAGTAGCAATTTGTCCAGAGTGTAAATCGATGGAATTTAGTAATTGGAATACACTGCACACTCATTTATGGCGCGCCCATCAAATCGATATGGAATTGTATAAATGCGATTTGTGTGACTTTAAGACACCTATATTTTCGAGACTGGCCAATACTCATGCCAAAATTCATTCTGATGATCGAAACTACAAATGTGAACAATGTGGAAAGGCTTTCAAAAACTCGAAGCAATTAAAAAATCATCGACGCTGGCATAGAGTTCAATTGAATTCCAATAATACATCGGCACCTCCCAAAGAACTACCACAACCAAACATACATCGATGTCCTGATTGTGGTTCGACATTTTCACATCAGAAAACATTAAAGGAACATTGTTGTAAGAATAATGCATCATCAATAATGAAATGTGATATTTGTCAGAAGGTTATGAGCACCAAAGCATCGTTAAAATTGCACTTGTTAACACACAAAGAAGAGAAACGATTCAAATGTCAACAGTGTAATTATGCCACAAATGATCATAATGCATTTCGGCGCCATCGGATGGggcatgaaaacaaaaaaatgtacgaTTGTCAATTCTGTGATTACAAATCCGTTCAAAGCGTAACGTATCAGAAACATGTACGTCACAAACATCCCGATAAGGCTGATACAGTTTTACACAAATGTTCGCACTGTCCATATACAACAATAAATCGGTCACTGCTAATTGTTCATCAAGCTAAACATCACAAGGATACGAATAATGAAATGTTGCAAACAACTGATGGTCAAAAGAATAATTCATCTGTTAATACAGCAGTTGACAAACTAGTTGCATCGAATATAGTTACGGAAAGAATAAACTCGATGGAGAATACGACGCCAGTCATTTCACCCGAtgtacaaaaaagtaaaataaaggTGAAAAGTAATCTTTTTACAGTATAA
- Protein Sequence
- MNDANYSMYDSYFCISNYQPSSIDSSLVDYDAQTTSHYSNNCELLSTTPAVEQRHHGGQTNIFPYLSHTRDEPNKIADTATNLCVSNTSAVPAGPAPTTFVNIPFVQIHTTDVQPQRTSYGNVFRRNISRQEEIKSEPIKSEGSDSSKERTNATPTPPRAPSATQKNQNAEDNAQNQNELVGERVENINEQENQHKEEDQLINQASCQVYKCSLCPFISLSDNQRYEHEKSRHADKQKEALRQELKCPGCTNVFYIQESLETHLRLDHIMPKDEALKLAHSIVQANSKDTQQSTKGLSGDSIQSEPQRKSRIYLKNVECLREPNRQPIEQTENQLFGNCSNNNSSNASLHQNQKAPKQKISIKSVDVLREPALLRRDYGMDNTNYSIFSADNTDNQQHGETVSNATDPASFNDNQNDMISMSRNQSNGDCDKTRKPKIYVKSVESFNLMPLEYIESQSNIFNNATQPFDSNSAHIPFIYETNTNIPISTSNVSGSYGHNDMTNNAYQIDINSSSNDNNYILDNNPLYLVNVDNMGINNCGGQVESVTLITDPTPPPDSSAVNLEEPINTANNNFPPAPPEPQRGTLHLRTVDELNLMNENEFQHPTNADISQMSKNSTNSEQRGTLHLRTVDELNLMNENEVQHLIAPNLDNNHSTEGLDNNINMNDDNLIGHGIYDDSDAFKFQDLDSQMANEWPETYDDLAEDINGIITEATNNPVTNNNNNREGHVVLNSTGDNQKTFSSSMEVDNPQMSLITIRDIEELTGGTSYIHDMVHDTNYANDNTSDVTSSIANISEQIDNSVVAKGNCGTSEDAENLKRELSNATPETKDSTTLGNECESNIPIIRVELHKEVPVTTEPRSPILTALSVCEINARSPKISSTLNKNSDCNIISSNELNSITQNSIVDRVPHSPIHIPNESSDNNFIKTSTSSVTSKNVNTITPLLATVTHMSTSQSSATTSSNDIPIPPLVPVTDSIMINREISSESDSAVPKDKFPPAQETPAEKGRIYVANNLMEPPKKPVSVRGRPFGSNRTRMALESTSTNDVFVKCSFKGCAFRFKKNETLEYHIKCHDIDPANVNSNQVAICPECKSMEFSNWNTLHTHLWRAHQIDMELYKCDLCDFKTPIFSRLANTHAKIHSDDRNYKCEQCGKAFKNSKQLKNHRRWHRVQLNSNNTSAPPKELPQPNIHRCPDCGSTFSHQKTLKEHCCKNNASSIMKCDICQKVMSTKASLKLHLLTHKEEKRFKCQQCNYATNDHNAFRRHRMGHENKKMYDCQFCDYKSVQSVTYQKHVRHKHPDKADTVLHKCSHCPYTTINRSLLIVHQAKHHKDTNNEMLQTTDGQKNNSSVNTAVDKLVASNIVTERINSMENTTPVISPDVQKSKIKVKSNLFTV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -