Mdom010574.1
Basic Information
- Insect
- Musca domestica
- Gene Symbol
- -
- Assembly
- GCA_000371365.1
- Location
- Scaffold19252:20020-23650[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 2.7 1.3e+02 3.0 1.2 2 23 198 220 197 220 0.89 2 14 0.0039 0.19 11.9 4.0 1 23 253 276 253 276 0.98 3 14 0.2 9.8 6.6 0.4 1 23 304 327 304 327 0.86 4 14 0.1 4.9 7.5 0.8 2 23 335 357 334 357 0.96 5 14 0.013 0.64 10.3 2.1 2 23 406 427 405 427 0.95 6 14 0.034 1.7 9.0 4.9 1 23 435 458 435 458 0.97 7 14 0.00052 0.026 14.7 4.0 2 23 468 489 467 489 0.97 8 14 0.00057 0.028 14.6 2.1 1 23 495 518 495 518 0.97 9 14 0.0014 0.069 13.3 4.1 1 23 545 567 545 567 0.98 10 14 0.01 0.52 10.6 3.9 1 23 573 596 573 596 0.98 11 14 0.0097 0.48 10.7 1.7 2 23 658 679 657 679 0.95 12 14 0.91 45 4.5 6.1 1 23 685 707 685 708 0.96 13 14 0.00029 0.015 15.5 1.6 1 23 826 849 826 849 0.97 14 14 0.072 3.6 7.9 2.5 1 23 855 878 855 878 0.97
Sequence Information
- Coding Sequence
- ATGCCTGCCCAGCCAACCTGCCGTTTATGTTTGGAATATTGTACTGAGGGCTATTGCGACCTATACAATGAGGACTTCCAGGTTGATTGTGAGACAACAGCAGCTACAGCGGCAAATGAGGTTTTCGATATGGTCAGGAAGTACTTTCCAGAGGATGTATTAAATATGGATTGCAATAAAGATCTCCGGAAATTATGTCTACAATGCTGGCATCATATAGAGGAATTCCATAAATTTCAAGAATCCATAATTTTGCTACAAAATATGAGAATGAGTGGACAAGTTATAGAAATGGTAGACGTAATAGAGGCCTATGAGCCGGAGGTACccattaaatttgaagagtttAATATTTGTGAGCCAAAGAACACAAACGACAACACGGAACAGCCACAAGAAGATGTGCAGAATATTGTGGAGGAGGATGTAAATGAGTTTGTTGTGGACACACGTCTCGACTCTGCTGAGGAAAATGAAACCGACAATTTTATAACAGAAATGACTGAATCAGAATACCACCTAGAGGCGAATACGGAAAATGTAAATACCGAAGATTTAGatgaattaatttcaaaatggaAATCAAATCTGGAATGTATGGTTTGTGGTGAAAATCACGATAGGTTTTCATTGCTGCGCAAACACTTCGAACAACAACATCCCCTGGAAGAATTCTGTATAGTCTGCTGTGGCTTGGCACTGCAAAACAATTTCGAAATTGAGGGACACATTTTGTATCACAAGGCCTTAAACGAGTTTCGATGTGACATTTGTATGAAACGTTTTGCCAATCGATCTTCCACAAAAAGGCATTTCAAAActaaacatgccatgaatttggctgctaaacatgacacgaatttggctTCGCGAAAGCACATTAAAAAGGAGAAGGAGAAATTTAAACTTTATAAATGTAAGACGTGTGATAAATTGTTTTTGGATAACATGGCAGTTAGGGTGCACAACGAAACCGAACATGGCGGCCAGCAAAGGGAAATTAGTTGTAAATTTTGTCACGGAACATTTGCCGAATATGGAGAATACCAATTGCACTTGAATCGGGAACATCAGGAGGAGTGGCAGGCCCAAAGGAATCAGGAGGCTATTGAAATGTTGCCGGAAATACGGCGACATATGGCGGCAGGGGTTAAATCGAAATTCTCCAAGATCCAAAAGCAGGCGAGACCCATCAACGATTCATTGGCCAACTGTAAATGTTGGATCTGCGGCAATGTTTATCATTCCCGGCGTTATTTGCTGGCCCACATTAGCCTACATGATGAGAACAAAGAGGCCAGGTATTCCTGTCAATACTGTTCGAAAAAATATCACCTACAAACAAGTCTCTCCTATCACATACGTCTCAAGCACGAACAACGTGACGCTGTTAAACCcctgaaatgtaaaatttgccACAAGGTGTATTACACCAAGAAAGCAATGCGCGAACATCAAAGCAAACACGAGGGCAGACCCTTATTTTCTTgtaaaatttgttccaaagaatattttctaagttCCAGTTTGTCCAGTCACATGAAAAGTTATCATTCGGGTGGGGTGAGAACCCGAAGAAGGGCATCGATATACGAAGAGGCTAGACTAAATTCAAGTGGCACGGTGGCATCGTATAAATGCCATAGCTGTGATAAAGTCTATCAAAGTAGACGAAGCCTCAGGGAACACGAATCGAAACATTCGGGCTACAAGGCCTACAGCTGTAACTTTTGTTCCCAACAATTCTATATGCAATCGTCCATGTACACACACATGAAAAAGCAGCACTACAGCCTGTATCAAAGGAAACTCAAATCGAAGCTTTCGAGAAGACCAAAAGAAAAGGTTACAACACCGAAAAATCAAAGCCTGGATGACTTGGTGAAAAGTTTGGATATTATGGCTCAAGTGGAAAATACTAAATCACATCAGCCACGAGAAGCCTGTAGTACCCTCAAATACTTTGGTTTAAAATGCCGAACCTGCAATAAAATCTATCAGTCGAAACGTAGCCTACGTGAACATGAGGCCAAACACAGCGGCAAAGAGCTGTACTCATGTCAGTTTTGTGCAAAAAAGTTTTTCCTCAAATCAACCAAAAGTTCACACATCAAACGTCATCATCCTCAGGGATGCAGGGCGGGCAAGGCAGGAGAATCTGCGATATGtaaaaatcaagaacaaaattttgcaatatattCCATAAGCGAAGTAGGAGAGGGAGGAGAAGGAGAAGTAGAAGTCAGCCAAGCAGAAAAGCCCGGGGCCTTGGAAGAAACAATTATTTCAACGACTGAAACTACTTATCTTAAAGACAATGAAGAAGATTCTTCTCTTACGGATCCCCTAACCAGGGAACCCAAAAATTTACTATCTCTACTAACAACAAATGAAACCCTAGCGAATAAGAGAAAATCACCAACGAGGAGCAGACGAAATGTCATCTCCCCCCTAGATGATCGACAAAATTATGCCTTCAAATGTTTGAAATGTGATCGTCGATATCAATCGAAACGTTCACTGCTCGCCCATCAACAGGTCATGCATGAGGGCAAAAAATCCTATAGTTGTAAGTTTTGTTTCAAGAAATTCGGCTTGGAGACCAGTATGTATAATCATTTGAGGATACAACATGCACAGGAGAGGTTGGCAGAGAAAATAAACAATGCGCAGAATTTACTGGCGGGCGAAGAAACAGATCAAACTTCATTGATTTGTAACATCTTAGATGATTATGCCAGCTAG
- Protein Sequence
- MPAQPTCRLCLEYCTEGYCDLYNEDFQVDCETTAATAANEVFDMVRKYFPEDVLNMDCNKDLRKLCLQCWHHIEEFHKFQESIILLQNMRMSGQVIEMVDVIEAYEPEVPIKFEEFNICEPKNTNDNTEQPQEDVQNIVEEDVNEFVVDTRLDSAEENETDNFITEMTESEYHLEANTENVNTEDLDELISKWKSNLECMVCGENHDRFSLLRKHFEQQHPLEEFCIVCCGLALQNNFEIEGHILYHKALNEFRCDICMKRFANRSSTKRHFKTKHAMNLAAKHDTNLASRKHIKKEKEKFKLYKCKTCDKLFLDNMAVRVHNETEHGGQQREISCKFCHGTFAEYGEYQLHLNREHQEEWQAQRNQEAIEMLPEIRRHMAAGVKSKFSKIQKQARPINDSLANCKCWICGNVYHSRRYLLAHISLHDENKEARYSCQYCSKKYHLQTSLSYHIRLKHEQRDAVKPLKCKICHKVYYTKKAMREHQSKHEGRPLFSCKICSKEYFLSSSLSSHMKSYHSGGVRTRRRASIYEEARLNSSGTVASYKCHSCDKVYQSRRSLREHESKHSGYKAYSCNFCSQQFYMQSSMYTHMKKQHYSLYQRKLKSKLSRRPKEKVTTPKNQSLDDLVKSLDIMAQVENTKSHQPREACSTLKYFGLKCRTCNKIYQSKRSLREHEAKHSGKELYSCQFCAKKFFLKSTKSSHIKRHHPQGCRAGKAGESAICKNQEQNFAIYSISEVGEGGEGEVEVSQAEKPGALEETIISTTETTYLKDNEEDSSLTDPLTREPKNLLSLLTTNETLANKRKSPTRSRRNVISPLDDRQNYAFKCLKCDRRYQSKRSLLAHQQVMHEGKKSYSCKFCFKKFGLETSMYNHLRIQHAQERLAEKINNAQNLLAGEETDQTSLICNILDDYAS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -