Mdom006451.1
Basic Information
- Insect
- Musca domestica
- Gene Symbol
- -
- Assembly
- GCA_000371365.1
- Location
- Scaffold19359:12275-18589[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.009 0.45 10.8 0.8 2 22 96 116 96 116 0.94 2 9 0.028 1.4 9.2 0.2 2 23 124 145 124 145 0.96 3 9 0.13 6.4 7.1 1.3 1 20 186 205 186 207 0.91 4 9 0.4 20 5.6 2.6 2 23 683 705 682 706 0.94 5 9 0.00035 0.017 15.2 0.6 1 20 794 813 794 815 0.95 6 9 0.0018 0.089 13.0 2.8 1 23 823 845 823 845 0.97 7 9 2.4e-05 0.0012 18.9 6.8 1 23 851 873 851 873 0.98 8 9 9.7e-05 0.0048 17.0 1.8 1 23 879 901 879 901 0.98 9 9 0.032 1.6 9.1 2.5 1 20 907 926 907 928 0.93
Sequence Information
- Coding Sequence
- ATGGAAATAGAAATTAAAGAAGAGCCTTTGGATGACTGTGAAAATGCCCAGGAAATATTCAACAAGCAACAATGCCAGGAAGAAGAAGCTGCAGTAACGAGTTTGCTGAAACAGCAATTGCAAATGGCCTTTATTAAGGATGAACCACTTGATGATAGTGACATTTTCACAGTTGTAGAGGAGCACGACCAGTTTATTACCGTCAGCGCAGCCGATATGAAAACCCAGGATGAACtgcaatttattaaaaaattgcacGAACCAAAGAGGACGAAATTTTCTGGTTCCTGTCCGAAATGTTTGAAAGAGTTCAACAAGCGTTCCTCATATTCAGAGCACATTAAACGTAATAACTGTATTGTCAAGCGAAAATGTTCTGCATGTCCATTGACTTTTGTCGAACCACAATCACTGCTGAAGCATTTGACACTACATCGTGATAATAAGTTCTTTTGTTCCCAAAATTGTGGAGCAAATTTTGATACACTACCTCTGTGCGAAGATCATGAAAAACGTATACACAAAATTACAAACCCACCAAAAATTCGCTATAAACATTTCTGCTCCTATTGCCGTGAAGGTTTCAAAACCGAATTACAATTGCATGTTCATTGGTTGCAAAAGGATGTAAATTGTGGCAAACTGTTGCATGCCGTTGCAACACATTACAGCATGACATCTGATATGATTAACAATACTGAGAAATTGGCAAATGAAACagacaataaaaaatcattacCACCGGCACCAACTTTCGCTGTAACTAAGCTTAGATTGAAAAGCAATATGCCACCGCCTTTGACAGCAATTAAGAGACCAAATGAAATGGTCGTGAAAGAAACAGAAGCAAAGCGTTCTAAATGTGTTAGCAATTTGAAAACTATATTGCACCATAAACCAAATGAAATGTTGACTGATTTACTTGCAAATATAGAAGTTAAAAAGGAATCAATGGATGAAGAGGAGGATGTTTTGAACACAACTCCTCTAATGCCGGAGGTTATTATTAAAACAGAGGATGAAAATCAAACTGATATCCAATATAAAACGGCGGATAAGAAACCCGGTGGAGACGTGTTGAGCAAAAACAAGGAATTAAAATCCCTATTTATAAATGATTCAAAGGAAATGAATCCTGAATTTCAtggtaaaataatacaaatgacAGCACCAAGTAAAGTGTCGCATGTGCCAGCTTtgcaaaaaaccaacaacaacaataaacaaaatattaacaacgatcaaattaaaaatagtctcaacaTTGTGGCAAATGATGTcaataataacagcaacagTAACTTGAATAATAGCCTTAAAaacataacaaatttaaaacttctACGCTTGGCACCAACTCCCATGGCTCcctcaaatattattttacctCCAAACATACAATTAATTCCACTGCAAAAACCTgggcaacaacaaacaattggAGAAATTATGTCGGCGCCAAAAATGACTCTTCAAATTCTCAAACTAATGCCTGCATCACACTTGCCAAACCATGCTAATAACAACATACTTTTCCAACAACctttaaatgttgtaaaaatagcAAATACTCCGTTGGTTATGTCACAACCAATGCcacaaaaacaaattccaaCAATGATGCAATCGCAATCAAATTTGAATTCTCTAACACCAATCTCAACTAAGCCCATTGAAACCCAAAATCCCTCCACGGTTGGAAACAACCAATCAAGCATCTCTGTAAACGGTAATACAACTCAAAATCGAGAAGAACGCATACAATATAtaccaaaaaagaaattaattgcCATCGAAAGTATGCCAGAGAAGAAACATATAATCGATACAATGAAACAGCAAATTGCCAAAGTTGCAGTAGGTGATACAAGTCTGACGGGTAATGAAACAAAGCAAACTAAGCCACTCATGAATATATCAAAAGATGTTGAATCGAGTATAAAAGTTCCCGGATGTCCGCCTActttatatttgccaatttTGAGTACGATAGATGTAGAATTGGTGGAAGCTCGCTATAAATACCCCGATTACAAATACAAATGGATTTGTCCATATTGTCTTAAGGATTACGACATTAAACGTTGCCTTAAAAGTCATTTAACAAAAGCTCATCATTTGACTAGCCGAGATATGGATAAAATCAACGTACAAGCAAAGGCGTTTAAAAATGAAGATGTAGCAACAGATGCAGAAAAGCAACAAAAAGAAGCTTATGGTCAAGAGcaaacgaaaataaaacaagaatcGAAACAAATATCAATTGATTTGCCATCTTCTGATGGAGGCTCCACAATACCAAATGATTTAGACAATAGCAGTAcaacacctcccccacaacccATAAAAATGTCAGCCCTTAATATTGTCAAGCCACGTTATATTTGTGAGAAATGTGGCCGTAAATGTTCATCGAAAACAATGCTCAATGATCATATTTCGGCAAATTGTAGCCGTGAACCCCAATATCCATGTCAGCAATGTCCCAAGAAATTTTATTCCCTAAGTACCCTGCAATGTCATATGACAATACATACGGGAGATTTGCCGCATAAATGTAATTATTGTGACAAACGATTCCGTACACGAGGTCAGGTCACCGTCCACCATAGGACACATACAGGAGAAAGGCCATTTGTGTGCCAGGTATGTTCCCAGCGCTTCACACACCGTGAAACGTTAATCGCTCATTTATCTCGTCATCTTAATATGAAACGCTACAAGTGCTATGGCTGTGATAAACATTTTTCCTGCATCAGCGCATTAAAAACACATCGTGAAATTCGTCCCGATACCTGTGGCAAAGTGAAATTCAATCCCCGAGCAATAGGACCACGTGTTCGCGTTGTACGTGGCAATGTTATCTTTGAGCCACAACCCGAAATCAATCCCTATTTACGTTCGGAGGATCCCAAAAATGTGTTGGCTGAATTACAAAATCAACCGGAGAGCGTTAAATAG
- Protein Sequence
- MEIEIKEEPLDDCENAQEIFNKQQCQEEEAAVTSLLKQQLQMAFIKDEPLDDSDIFTVVEEHDQFITVSAADMKTQDELQFIKKLHEPKRTKFSGSCPKCLKEFNKRSSYSEHIKRNNCIVKRKCSACPLTFVEPQSLLKHLTLHRDNKFFCSQNCGANFDTLPLCEDHEKRIHKITNPPKIRYKHFCSYCREGFKTELQLHVHWLQKDVNCGKLLHAVATHYSMTSDMINNTEKLANETDNKKSLPPAPTFAVTKLRLKSNMPPPLTAIKRPNEMVVKETEAKRSKCVSNLKTILHHKPNEMLTDLLANIEVKKESMDEEEDVLNTTPLMPEVIIKTEDENQTDIQYKTADKKPGGDVLSKNKELKSLFINDSKEMNPEFHGKIIQMTAPSKVSHVPALQKTNNNNKQNINNDQIKNSLNIVANDVNNNSNSNLNNSLKNITNLKLLRLAPTPMAPSNIILPPNIQLIPLQKPGQQQTIGEIMSAPKMTLQILKLMPASHLPNHANNNILFQQPLNVVKIANTPLVMSQPMPQKQIPTMMQSQSNLNSLTPISTKPIETQNPSTVGNNQSSISVNGNTTQNREERIQYIPKKKLIAIESMPEKKHIIDTMKQQIAKVAVGDTSLTGNETKQTKPLMNISKDVESSIKVPGCPPTLYLPILSTIDVELVEARYKYPDYKYKWICPYCLKDYDIKRCLKSHLTKAHHLTSRDMDKINVQAKAFKNEDVATDAEKQQKEAYGQEQTKIKQESKQISIDLPSSDGGSTIPNDLDNSSTTPPPQPIKMSALNIVKPRYICEKCGRKCSSKTMLNDHISANCSREPQYPCQQCPKKFYSLSTLQCHMTIHTGDLPHKCNYCDKRFRTRGQVTVHHRTHTGERPFVCQVCSQRFTHRETLIAHLSRHLNMKRYKCYGCDKHFSCISALKTHREIRPDTCGKVKFNPRAIGPRVRVVRGNVIFEPQPEINPYLRSEDPKNVLAELQNQPESVK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -