Mdom002692.1
Basic Information
- Insect
- Musca domestica
- Gene Symbol
- -
- Assembly
- GCA_000371365.1
- Location
- Scaffold197:47262-57039[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.1 5.2 7.4 0.9 3 23 847 868 845 868 0.91 2 12 0.35 17 5.8 0.3 6 23 879 896 879 896 0.97 3 12 0.011 0.55 10.5 9.9 1 23 902 925 902 925 0.98 4 12 0.0027 0.14 12.4 0.8 2 23 967 989 966 989 0.96 5 12 0.058 2.9 8.2 0.2 6 23 999 1016 999 1016 0.99 6 12 0.11 5.5 7.3 6.9 1 23 1022 1045 1022 1045 0.97 7 12 0.015 0.75 10.1 2.1 2 23 1086 1107 1085 1108 0.92 8 12 0.069 3.4 8.0 1.7 6 23 1118 1135 1118 1135 0.96 9 12 0.0019 0.093 12.9 1.8 1 23 1141 1164 1141 1164 0.95 10 12 0.016 0.81 10.0 3.1 2 23 1210 1232 1209 1232 0.94 11 12 6.7 3.3e+02 1.7 0.8 6 23 1242 1259 1237 1259 0.97 12 12 8.7e-07 4.3e-05 23.4 3.9 1 23 1265 1287 1265 1287 0.99
Sequence Information
- Coding Sequence
- ATGACCTCCACTAATGAGAAATCCCTTAAGAATATGCTCCGTAAGTCCGAATTGGAAAAATCGAAGGCTTGTAGTGCTAGAGTTAATTTGAAGATCTCGAAAGATGAAATTGGGCCTTCCGTTCATCGGCCATTCATTACCTTAATAAAAGCTGAGGATGAAGGCGCGCTCATGAACAGTTCTAATGGTAATGCAAATGATAGCAATCAAACGGTGGCGGGGGATGATCAAATGGATATATCCGAATcgaatttgaaaaatcttcAGAGTAAGAGCAACGGTTTGCCGCCAATCACACATGACAGTGAAGACCCTGTCCTACCAAGACCTTTCATCACAAAActgccaaaaattaaaaaagaagaattaAATCAGGATATTCCAAATAATGATGAAGCCTTGGATATATCCCAGTCACAGTTCGATTTGCTTAGTCAGGAACTTAAGACTACAACATGTGATAATTTTGCAATGGACAAAAACCAAAAGACCGTCAAGAATAATtatgattttccaaaagatGATATAAAATCTGACAATTCGCAAACTGAAATTAATGTCTTGCCAAGTATAAGGAAGAAACCCAGAGTTAACACTGAGGAAAAACAACTTGTCTTCCAAAATATGCCAAATAACAATGGTGATTTAAGTGATATCTCCAAACCTTTATTGGACGACTCCAATGTCAACAATGATAACTTTAAAGGAACTAAACGAAAAGCACATAATTTCCCAAAGccaattaaaagaaataaaaagccAACGCTGGAACATACAGATCAAGTATTAataaaatgtcctaaaattaAAAGTGAGAAAGAAGTTATGCCACCAACCAATACCGATAGAAAAGATCTGCCACAGAATGTATTAGAATCACAAATGAGATTAACTAAAatagataaaataaaaactgaaaacgATCCAATGATGGATCATCCTCTTCAAAGCAGTAATGAAGCGATATCTGTAACTAAATCGACtagtaaaaaatttaagaatttaaaatctgataaaaagagcaaaagcatagaaaataaaCTGAGCTCAGGCTCCCCAAATAAGAAGTGTGGCGAGAAACAtaatgttgaaaatattcttaaactaaaaacagaaataacGCCTGCTAACGAGGAGCTAAACATGAATATATCAACAACTCCATTGCAGAAAGATGAAAATACATCCACAAGAAAATCCCATAGAATCAAGTTTGAAAGTTGGAAAATGAAGGAAATGCGCTCCGTGACAATAGGTCGTAAAAGGAAACTCGACTCTTCCGCTGATGCAATTAAGACAAAGCTTGTCCGTTCTATaaccaaccaacaaaatgagaaatatgtttcttccgatCCAATACAAAATGATGTACAAATTGTGGATCTTGATATCAATAACCAACCAAAGCAGGCGAAGGATAAACTGATCAATACCCAAAGTATCCAAGAAGATGAAATCGGTTGTAATGTATCTTCGGATACAATACAAAATAATGTACAAATTGCGGATCTTGATATAAATAACCCACCAAAGCAGGCGAAGGATAAATTGATCAATACCCAAAGTATTCAGGAAGAGAAAATTGGCTCGACAAGAAAATCACAAAGAATTAAATTCGAAAGTTGGAAATTAAAGGAAATGTATTCTACGATCGCAGAACGAAAGAGAAAACTTGCCTCTTCACAAATCACAAATAAAGCCGAGCTATTTCATTCTACGATTTCCAATCACAATAAAGAATATTCTGAAAATCTAAAtagtgtgcatattacggattcCAATATTGATGTCAAACCAAAAAGATTAGAAGGTAAACTAATCTTTACCAAAACTCAACAATTTAACCACAACAAAATTGCCGTTGTGAGATTACCCAAAATAGTGGGTAAAAGTATTAAACAAACGGATAATAATGTATTATCTGAATTCAAAATGGTTGGTAAGGATCTAAAGAACTCAAAAATTGATGAAACAAAACGCGAGTTGCAACATAACCAGAAAAATACAGCCAGAAGTAACGTAGACATGGACAGTGCATCTAAAGTAGTCGTAAGAAGTTTTCCTAGAATCAAAATTGAAACTACATCTGCTAACCGAATTAAGGAGAATATACCGAAACTAAAAACCGAAATACCGgATAATGATATTTCCCCCATTAGAAAATCTCACAGAATTAAAACGGAAACTTGGAAATTAAAGGAAATTAATTCCATGAAGCAGacttttggaagaaaaaataaGGTACAACAAATCAATGAGGAGCAGACAACCAAAGAACCCAGCGAAGAAAATGATCCCTTCGAAACTGATGATGATTTAAAtgatttggattttgaaattgataGCCCTCCAAAACGAACcaagttaaatttcaaaaaaatgaaaagcaaaacaaatggacgtcatcccaaacaaaatcatgaattggaaataaaCACTTCAAATCCATTAAATTCTACGGCCCTGATGCGGCCGATAAAAAGTACCCGCGAAGAAGAGCTGGACAATATTATAGCCCAATGGAAACCCGAACTGGATTGTATGGTATGTGAAAAACCATTTGCCACCTACACCCTGCTGCATGAACATTTCAAGGATCGCCATCAGCATAAACATGAATTCTATATACAATGTTGTGGTCTGAAGattaaaaaacgtggacatCTGGCCGAACACATAAGGATACACACCGATAAGAAAGCCTTCAAGTGTACCCACTGTAAGATACGTTGTCATCGCAAACGTAATCTCATCTATCATATGAGAAAAATACACAATATTAGTGCTAAGGAAATAGTTCCGGAAAGAGGCCTAAATCCGGAATCATCACAGATTAAATTATCCACGCAAATAATTAGGAATAACGATAGATTCATAGAACAATTTCTACCCAATTTGGAGTGCCCTCGTTGCAGGCAGATATTTCCCGTTTTTAGCAAATTGGAAAGGCATTATCGGAAGCGGCATAAGGATGaggaatttcacattttatgttgTGGCTATAGGCTGACAACACAATCCCTGTTAGTAGATCATTTAAATCGGCACACTCATCCAAGGAAACAtaagtgtaaattttgtaatgccTGTTTTACGATGCAGCATGTCATGGAATATCACATGCGGGTGGATCATAAAAAGAATTCCAAAGACTCTTCAAATGACAACACTGCGGAAGATGTGGCGGATGCTCATGCGGAAGTGCTAAGCATAAAGGAAAGTGATGATTTTATATCACGATGGTTACCCAGTTTGGAGTGTCATGTTTGCAAGGAGGAATTCAAGAGCTATTCTTCGTTGGGTGAACATTTCGATGTGCACCATGCTGAGCAGCAAAGTTATGTAACATGTTGCGATCATCGATTTTTTACTCGCTCCAAACTGCAAAGGCATATCGATGGCCATATAAACAGTAAAGCATTTAAGTGTCAGCTGTGTGGCAAACGTTATACCAGAAATGAACGCTTAGAATTCCATATGGCCAAGCAACATTATGGCACAATTTCATCTGTGACCAGTTATTGTGAAGATCAGCCCAGCCCTGGGACAGAAACGCAAAATGTCTTAACGAAAAGAAAATCCCTTAAAGATCTTGATCGTACCATAGCCCAATGGAAACCTAAACTAGAGTGCCGAGTGTGTCATAAAACCTATGCAACTTTTACATTATTCAGCCGGCACTATCGTGACACACATCCCGCAGAACAATGTTATATCTCCTGTTGTGGCTGTAAATTTGCTGGCCGTTATGATATTGTCGAACACATCAAATATCACAGAGATCCAAATGCATTTAAATGCACCCAGTGTGGGCGTTGTTTTAATCGCAATCGtggtctgatattacacatgCGAACTCATCGAAATTAA
- Protein Sequence
- MTSTNEKSLKNMLRKSELEKSKACSARVNLKISKDEIGPSVHRPFITLIKAEDEGALMNSSNGNANDSNQTVAGDDQMDISESNLKNLQSKSNGLPPITHDSEDPVLPRPFITKLPKIKKEELNQDIPNNDEALDISQSQFDLLSQELKTTTCDNFAMDKNQKTVKNNYDFPKDDIKSDNSQTEINVLPSIRKKPRVNTEEKQLVFQNMPNNNGDLSDISKPLLDDSNVNNDNFKGTKRKAHNFPKPIKRNKKPTLEHTDQVLIKCPKIKSEKEVMPPTNTDRKDLPQNVLESQMRLTKIDKIKTENDPMMDHPLQSSNEAISVTKSTSKKFKNLKSDKKSKSIENKLSSGSPNKKCGEKHNVENILKLKTEITPANEELNMNISTTPLQKDENTSTRKSHRIKFESWKMKEMRSVTIGRKRKLDSSADAIKTKLVRSITNQQNEKYVSSDPIQNDVQIVDLDINNQPKQAKDKLINTQSIQEDEIGCNVSSDTIQNNVQIADLDINNPPKQAKDKLINTQSIQEEKIGSTRKSQRIKFESWKLKEMYSTIAERKRKLASSQITNKAELFHSTISNHNKEYSENLNSVHITDSNIDVKPKRLEGKLIFTKTQQFNHNKIAVVRLPKIVGKSIKQTDNNVLSEFKMVGKDLKNSKIDETKRELQHNQKNTARSNVDMDSASKVVVRSFPRIKIETTSANRIKENIPKLKTEIPDNDISPIRKSHRIKTETWKLKEINSMKQTFGRKNKVQQINEEQTTKEPSEENDPFETDDDLNDLDFEIDSPPKRTKLNFKKMKSKTNGRHPKQNHELEINTSNPLNSTALMRPIKSTREEELDNIIAQWKPELDCMVCEKPFATYTLLHEHFKDRHQHKHEFYIQCCGLKIKKRGHLAEHIRIHTDKKAFKCTHCKIRCHRKRNLIYHMRKIHNISAKEIVPERGLNPESSQIKLSTQIIRNNDRFIEQFLPNLECPRCRQIFPVFSKLERHYRKRHKDEEFHILCCGYRLTTQSLLVDHLNRHTHPRKHKCKFCNACFTMQHVMEYHMRVDHKKNSKDSSNDNTAEDVADAHAEVLSIKESDDFISRWLPSLECHVCKEEFKSYSSLGEHFDVHHAEQQSYVTCCDHRFFTRSKLQRHIDGHINSKAFKCQLCGKRYTRNERLEFHMAKQHYGTISSVTSYCEDQPSPGTETQNVLTKRKSLKDLDRTIAQWKPKLECRVCHKTYATFTLFSRHYRDTHPAEQCYISCCGCKFAGRYDIVEHIKYHRDPNAFKCTQCGRCFNRNRGLILHMRTHRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -