Basic Information

Insect: Musca domestica
Gene Symbol: -
Assembly: GCA_000371365.1
Location: Scaffold18771:41948-45460[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 4.4 2.2e+02 2.3 0.1 2 23 225 246 224 246 0.91

2 11 0.004 0.2 11.9 0.3 1 22 299 320 299 323 0.90

3 11 0.035 1.7 8.9 1.6 1 20 369 388 369 390 0.95

4 11 0.0053 0.26 11.5 1.2 2 23 420 440 419 440 0.96

5 11 2.8e-05 0.0014 18.6 0.6 3 23 456 476 455 476 0.98

6 11 0.00019 0.0095 16.0 0.3 1 23 485 508 485 508 0.96

7 11 0.00013 0.0064 16.6 0.3 2 23 514 535 514 535 0.97

8 11 1.2e-06 5.8e-05 23.0 0.8 2 23 541 562 540 562 0.97

9 11 0.0013 0.062 13.5 2.2 1 23 568 590 568 590 0.98

10 11 0.015 0.72 10.1 5.1 1 23 595 617 595 617 0.95

11 11 0.33 17 5.8 3.3 1 23 622 646 622 647 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	4.4	2.2e+02	2.3	0.1	2	23	225	246	224	246	0.91
2	11	0.004	0.2	11.9	0.3	1	22	299	320	299	323	0.90
3	11	0.035	1.7	8.9	1.6	1	20	369	388	369	390	0.95
4	11	0.0053	0.26	11.5	1.2	2	23	420	440	419	440	0.96
5	11	2.8e-05	0.0014	18.6	0.6	3	23	456	476	455	476	0.98
6	11	0.00019	0.0095	16.0	0.3	1	23	485	508	485	508	0.96
7	11	0.00013	0.0064	16.6	0.3	2	23	514	535	514	535	0.97
8	11	1.2e-06	5.8e-05	23.0	0.8	2	23	541	562	540	562	0.97
9	11	0.0013	0.062	13.5	2.2	1	23	568	590	568	590	0.98
10	11	0.015	0.72	10.1	5.1	1	23	595	617	595	617	0.95
11	11	0.33	17	5.8	3.3	1	23	622	646	622	647	0.96

Sequence Information

Coding Sequence: ATGGAACTAAGACGTTGTCGCATATGTCTAAATGACTCCCATCGTTATTTGGATATCTTTGATAATTGCAAATCCACATTTACCTATGCCGATAATATACGTCACATAGCCGAAGTGGATATCCAGCAAAACGATGGTCTTCCCCAGAAAATATGCTGTGATTGCTCTGCGGAAATACAGAATATATTCGAGTTTGGTTTACTTATCCGCCATGCAGACGAGGTACTGCGAAAGGAATTGCAGCAGGAGAAATTGAACACCGTCGAAGCTGAGGATGGAAATATTCACATATTGGAAGAAGATTGTTTCGTGGCAGAAAATGATGATGGTATAACCGGTTGTGTGATGGAGGAGGAAGAAGTGCTGACGGTAGATGGTGAATTGGTAGAGGAATATgACAATTACCAAATAattgaagaagaaatattcgAAGTTGTTGAAGACGTGCAAGATGTGGAGTCTCATAACAAGCCTCAGACGCTTAGAAATAGTAATGATCTGAATGGCAACTTGGAAGAATTGGCTCAAGTGGCAGCCATTGCCCAACGAACCGAGGAACTGGATAAGCCCGAATCGCGAAATTATTGCCATGAAGATGAATGTGATGATGACTATCAGATAGCCTATAATCCAGCAGAGGAAccattttataatttcaaaccACCCAAATGGAAATGCATAGAATGTAAGCGGGTGCTGCGCGGAGATGTCTCATATGAAGGTCACATGAATATGCACAAACAATTACGTCCTCATAAATGTCCGTCATGTAAATGCCAGTTTCGATGtcgaaatgttttgaaaaaacacAAGCAGCTCAGACATAATAGACCACAAGAGGAAGAAATCAATTCGAAACAAGTCGAATCAAATAAGAAGGATCCCTCCGAACCTTTCAAATGCCTAGAATGCAATAGGGAATTCACAAACGATTGGGAACTTCTATTGCATGAGCTTACCCTAACGCACGGTAATCGTTGTCATCTAACCACCTGCCCCTTTTGTCCTGATACTGCAGTAGACGATTTAATCGACCACTTACAACGCGTCCACATACGTAGAGAAGAAAACAATGAGGAAGAGGCAACACATTCGGATTTGGTGTATCAATGTGATTATTGTTCACAAATATGTAAAACAATAGAGGAATTACATCTTCATCAGGATCAGTGTAATATGTCCGCCACAGAGGATCCGGATATAACAGTTGAAGAGGAATTTGAGGAGAACACGCTGGACTCGGTGGATGTCATAGTCTATTGTGAAGTGTGTAAAAAGAAATTACTAAAGAAAAACCTAAAACGGCATATGCTGGTCCACGAACGAAAAGGTAGGAAAACAAGGGAGGATCCTAATAAATTGTTATGCGCCTACTGTCCACGGGAATTTAAGAATCAAAAATCTTTGCAACAGCACGAAAGAATTCATGAAGGCGAATCTTCGGAGGCAACCTATGCCTGCGACGAATGTGGTCGCCAATATTCATCACAACTTCTGCTGGAGACACATCGTAAACAGGCCCACAAAGAACGTGACAACGTCTGTTCGATATGCGGTAATGCCTTCAAACTAAAAAATCAACTGGTAAATCATATGAAACTACATTTGGAAAAGAACATACCATGTCCGCATTGTGACAAGAAATATGCTAGACAATTCGATTTAAATGTCCACCTGCGATCACATACCGGAGAAATGCCTTATGCCTGTCATCTGTGTGATAAACGTTTCGCCATAAAGGTACGTCTGACATATCATCTGCAAAAACACTATGGCGTCAAGCATCGTTGCAAAGAATGTAATGCCGAATTCAATTCCAAACAGAAACTCAAAACCCACTCATTTAAACACACTGGCATGCCATATCGTTGTGAACTGTGCGACGATCATGGTTTCTCAACGCGTGTTGTGTTCAAACGCCACCTATCTCGTGTACATCATTCTACAATGTCCGATGAAGCCCTGAGTGAAATGTTTCAACGCAATACTGGGAAAAcgataaaaatcaaacaaattagTACTGCAGATGAAGATTAG
Protein Sequence: MELRRCRICLNDSHRYLDIFDNCKSTFTYADNIRHIAEVDIQQNDGLPQKICCDCSAEIQNIFEFGLLIRHADEVLRKELQQEKLNTVEAEDGNIHILEEDCFVAENDDGITGCVMEEEEVLTVDGELVEEYDNYQIIEEEIFEVVEDVQDVESHNKPQTLRNSNDLNGNLEELAQVAAIAQRTEELDKPESRNYCHEDECDDDYQIAYNPAEEPFYNFKPPKWKCIECKRVLRGDVSYEGHMNMHKQLRPHKCPSCKCQFRCRNVLKKHKQLRHNRPQEEEINSKQVESNKKDPSEPFKCLECNREFTNDWELLLHELTLTHGNRCHLTTCPFCPDTAVDDLIDHLQRVHIRREENNEEEATHSDLVYQCDYCSQICKTIEELHLHQDQCNMSATEDPDITVEEEFEENTLDSVDVIVYCEVCKKKLLKKNLKRHMLVHERKGRKTREDPNKLLCAYCPREFKNQKSLQQHERIHEGESSEATYACDECGRQYSSQLLLETHRKQAHKERDNVCSICGNAFKLKNQLVNHMKLHLEKNIPCPHCDKKYARQFDLNVHLRSHTGEMPYACHLCDKRFAIKVRLTYHLQKHYGVKHRCKECNAEFNSKQKLKTHSFKHTGMPYRCELCDDHGFSTRVVFKRHLSRVHHSTMSDEALSEMFQRNTGKTIKIKQISTADED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -