Basic Information

Gene Symbol
-
Assembly
GCA_000371365.1
Location
Scaffold19292:47603-60637[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.05 2.5 8.4 0.1 1 22 1035 1056 1035 1059 0.88
2 8 0.13 6.3 7.2 3.7 1 23 1460 1483 1460 1483 0.97
3 8 0.00012 0.0058 16.7 1.7 2 23 1507 1528 1507 1528 0.97
4 8 6.5e-05 0.0032 17.5 3.0 1 23 1534 1556 1534 1556 0.97
5 8 6.2e-06 0.00031 20.7 0.2 1 23 1562 1584 1562 1584 0.98
6 8 0.0036 0.18 12.0 2.7 1 23 1590 1612 1590 1612 0.98
7 8 0.00027 0.013 15.6 0.1 3 23 1620 1640 1619 1640 0.97
8 8 0.00037 0.018 15.1 2.9 1 23 1646 1669 1646 1669 0.98

Sequence Information

Coding Sequence
atgctaacaacaaaaattttacccACCCGGGACAGTAGTGGTCTACACAAAACGGCGAAAATGAACAGAAAATCCACTCTCAAGACTGAGAGTGGCCAATCCATTTTAACCAAGGCCCTGCAACAACCTTTGATCTTGGCTCCAACTACGGCCACCAGCACAGGCCGTTATCGCCGTTGTACCAATTCTCCAACATCGTCATTGGCCACCTGTGACAGTGATTTGGCCGAAAATTTGGACTCACGTAATTTTCCCGATCACCTGGGCTGTGGTGAGGTTTTCACCTGGCATTGTGAGGGTGAATTCTATGCCGTCGAATGTCGCCTATGTGATGATCATCCTTTGTGTCCCCTCTCCGAGTTTCCCCTGCACATGGAGGCGTGGCATACCGAATGGACGGGCAGGCTAACCATTGATGGCGAGGAGCTGGAAGCTGACAGCAATGATGGAGATGAACAGGAGAATACCTCAGGCCTGAGTGAGGAAATTGCGGAGGTGGAGGAGGAAGAAGGGGACTACGATGAAGAACACAATGATTTATACCATGTCCTGGCTTTGACAAATCAAAACAATGAAGACAGTGGTCTGTGTGAATACGATCATGATGAGCCGAATGCACCAACCTTGGGCACAGCTTATGATGAGGATGAACATCATCAACGGCTGTTGGAGCCATTCGAACAGGTATTGATTGAGCAAGAGGTGGCTgaggaacaacaacagcaacagcagcagcaacatcatcagcatcagcatccgccacaacaaGAAATCGTGGAAGACCAAAATGAAGAAGAAAGTCATGAAAgtcaaattaatgaaaattccGCCGTAGAGCAGAGGGGAGTGGCAATCACACCAAGAGGTGGAGAAGAAGATCAATTAGTGGCCGAACTGGTGGTGACAGACgttaaaacaaataatacaaCGGTTTTAACGGCAGCACCTCAAACTCAACAGCAGACCAACAGCTTCCAAAATcgaaaatcaaaacaatatcCAATGGAGAGCAGCAGTTGTGCTGATGATGGTGGAACTCTCGAGAGAAAACCCGATTTTTCCCCATCCATTGTGAAAGAAGAGTACTCTCTAAGAGAATATAATGTAGAGAGCGAATTAAGAgagtttattttgaaaataacggGAGAGCCCCAAATccccaccaacaccaccactacaaccaacaacagcaacagcgaTGGGGAAATCTTGCACGCAGCCTCACAAGTCATGGCTCAAAAAGAGAAAGATCCGCTATCAAGTTCTTCTTCATCGTCTCCATGTTGTTGTTGGGACAAAAATAAACATGATCATCAACAcgaacaacaccaacaccaacaccattGCCCGAAAGAAAGTTGTATTGGAAAACCCGAATTAAAGAAATTAACAGGTGAAATTAAGAAAGAGCCAGAACAGGTCAAACAAGatctaaaacaaaaacaacaaatcaaacgggaagcagaagaagaagatgaagtcGAAGTTCCAAGACCGATTATTCTGGAAACTTGCAAAGATTCCATTTTAGAAGAGAAAGTAGAACCCCCTTCTCCTACTTCCTCGCCGCCGTTGCCAACAATTCCAGAAGAAACGAATGCGGCagcacgttgggcgccatcccGCAAACGAAAATGCCGACGGAATTCCCAACCCATTGGCAGTGTTGCAAAACCAGCCCCCAGCAAATATCTTAGTTCTTATCagaaatttttggaaacaacagcaacaacagcggaGGTGGAGCCGGAGATTAACAGCTCCCCCGAACCGGAAAATGAGCCCAAGCGCCGAAGGACCTATTCCAGGGCCTGTAAAAAATCAACACCATCCGCCAAGGTCCAGAAAATAACTGAAGAACTACAAATTAACACCAACTTGGACCAAGGAGGCAaaggcgaagaaggagaagaagaagaagcagccgCAACAGCTCCCCAAATACCCTACAACTTCCTGACACCCAGCCAAAGTGAGATCTCGTCGGCCAGCTCTCCCAACTCCGAAAAGTCACAGAAAATACACGAATTGGTAAAGCAGTGTGAGAGAATTGCAAGGGAGCACAActcatcctcctcatcctccacatcctcTGCTTCATCCGCTTCCTCCACAATATCCAGCATTTCGAATAAGACACGAGAATTGCGTCGGCATACCAATAACAGGCATCGACGATCTCTTACCCCAGTTGAGGTGTGTGACATACAACCCACGGTACCGCTAAACGAACACCTCCTCAACATCTATGATGAGTCGAATGGTGGCAACATGTCACCCCAGTCTCTGTCGGAACATTTGGAATCGCTGGCCTGTAGCCTGCTGGATTGTGATGAATTCCCCGACGATGATGATCGTTCCGTGGCCTCTACCACATTGACGGGCGAAAACCTCTTTGAATCCTCACCACCCTCACCCGCCTCGCCCAGAACCGAagaggaacattttgagttccATGAACCAAGGGAGAAGTTGAACAAGATTCATGTCATGAAACTCATTGAACTGTACAAGCAGCAAACCCGACTGTGGGATCAAAGCCACACGGAGTTTTGTGAACCCCATCTGTGTCGGCAGTCTTGGGAGTACATAACCGAACGATGGAATGCCTTCTGTGATCGTAAATTCCACATAACCGAGGTAAGGATAAGGATTTCCACTCTCTGTCAGAGGTATCTGAAGGAACGGGAACGCATCCAACGCAACGGAGATCGGGAGGAGAACATTAAATTTCCCTACTACAAGGAGTTATCCTTTTTGGAGCAACATCGTTCGCTGCAAAAACGCCGCGAGGTCTATGAACAGCAAAACGACAAGATTTTGGATATCTATCAGCGACATCTGATCCTGTGGCATGTACGCTACTACAAGGTGCGTCAGGTCAAGGAACGCAACAAGGCATTCCAAAGTATCAGTGTGGAGTTGAAAAATCACGGTATCTATCTCTCATCGTCGGGAGTGCAGAAACGCATACGGTCACTGCGTAAATGTTATCGTTTGGAGAAGATTCGCTATCTCCGGGCCCAGGTGGAGAAGACCGAGTTTGTGCCCACATTTAAACACTATGCCAAAATGCAGTTCCTGGAGAAACACATTGAGCCCTTCGTGTGTCGACTGTGTGGTAAAATTTTCGAAAGTCTACCACCCTTTAAAGACCATGTGGAGACCTCAAGTCATGGTAACATTCTCGAAGAGGAAGATGATGAAGAATTGGAAATATTGGCCACCACGAATTCCCTAGCCTCCACCACCAGCCCCGATACCATACTCTGTGGCAACAATGGCCAATTTGAGATCAGCATGCAGGCCGGGAATCAAAATTCCGTAAATCTTTTCATTAAACCTCTGCCGCCACAGGGGGTTAACACAATTTCTCCGCACAACCAACACCCTGCCACGCTTTGTGACTCCACCATTTCGGACTTGCCCACCGATGATCAGTTAATGGAAGGCATTATTCAAACGGTATCAAATGACGATGACTTTGTTCCTCAAACACTTGATACGTATGTCCATTCATATGAAGATCAGGGTGATGTTACAGCGTTCCTAGAATCGGCGGCGAATAATATTGGAAATGCGACGGAGATATTAACGGCTTCGGATCAACAATGCACGGAGGATCCAGTTGCAGTGTTTAatgaaaatcttccaaaaattctgGGACGACGGCGTTCAACCAAACCAAAATCCTCCGATGTTGTGGACGATGAGTGCCATTCCGGCGATGGTGATGCCCAGTGTGCCCGTCTATCGGACGATGAAATTCGCCTAATGATCTCCGTATATCGTCGTTACCGCCAACTATGGGATCCAAATCATTTGGATTATAATACACGAAGTTTGCGGCGCCAGGCATGGTTCTCGCTGACATCGGAATTTAATAAGATCTTACATCGTAACTTTTCGTGGCGTTCGCTGTATCGGAAGTTAATCGACTACGCTAAATACTATAAGAAATTGGTGGCCGAACAAAGTCCGGGAGATATTAAATGGGCGTTCTACAAGGATTTGACATTTTTGGATGATGTGATCGGTGTAAGCAATGAAATGGGCAAGTCCATACACGACCGTAGCGTAACCCTAAAACTCATTGAAATCTACAAAGATCTACCGCAACTGTGGAACACCCGAGATCCGGATTACAATAAGAGGCCGGTGAAGCAACGTAACATCAACATTGTCTACAATCGCCTGATCGAGGGAACCAATAAACAAATCAGTCCCGAACGTATTAAGAATCGTATCATTGAGCTGAGGACGCAATATCGTGCCGACAAAAAGAAACGTATCCGATGCCTGAATAACAAACAGAAATTCTTTCCCGATTTTGAATATTATGAGGAATTCAATTTCATTGATGCCCACATCGATCCGTTTGAGTGTGAGTTCTGTGGTATGGATTTCAAAAAGCTCAAAGATTTCAATTGCCATCTGCGCAAGGAACATGAACCGAAGCGAAGAAAATTCCGTGGTAAAGGTGGCGATGAGGCATCGTCATCGCAAAATTTGGATAATGTTTGTCATATTTGTGGGGCGAAATTCAGTAATCGTGGCAATTTGGGTCATCATCTGATACGTCACGAGGGTGTGCGTAATTTCGCCTGTACCATGTGTCCCAAGAAGTTCTTCAATTCGCATTCATTGAAAATTCACGTGCGAAGTCATACCAAAGAATGTCCATATGTGTGTGAGAAATGTGGTCTGTCGTTTGTGAATGCCAGTAAACTGAATCAACATGTCCTCAGGCATACGGGAAAGAAGGATTTTAAGTGTGATCACTGTCCCAAGGCATTCTTTACGGCCTTTGAAAGGGATCGCCATACTCGATGGCATTTAAATATACGTGATAAAAATTGCCCGATTTGTGGTAAATCTTTTGTCAAGGGTTCCTCCTATTATGCCCATCTGATGTTGCACAGTGACACGAAACGTTTCAAATGCGACAGTTGTGACAAACAATTTTCCCAATATGCTGGATTGTACAAGCACAGGAAGAGATATCACAGTCCGTAA
Protein Sequence
MLTTKILPTRDSSGLHKTAKMNRKSTLKTESGQSILTKALQQPLILAPTTATSTGRYRRCTNSPTSSLATCDSDLAENLDSRNFPDHLGCGEVFTWHCEGEFYAVECRLCDDHPLCPLSEFPLHMEAWHTEWTGRLTIDGEELEADSNDGDEQENTSGLSEEIAEVEEEEGDYDEEHNDLYHVLALTNQNNEDSGLCEYDHDEPNAPTLGTAYDEDEHHQRLLEPFEQVLIEQEVAEEQQQQQQQQHHQHQHPPQQEIVEDQNEEESHESQINENSAVEQRGVAITPRGGEEDQLVAELVVTDVKTNNTTVLTAAPQTQQQTNSFQNRKSKQYPMESSSCADDGGTLERKPDFSPSIVKEEYSLREYNVESELREFILKITGEPQIPTNTTTTTNNSNSDGEILHAASQVMAQKEKDPLSSSSSSSPCCCWDKNKHDHQHEQHQHQHHCPKESCIGKPELKKLTGEIKKEPEQVKQDLKQKQQIKREAEEEDEVEVPRPIILETCKDSILEEKVEPPSPTSSPPLPTIPEETNAAARWAPSRKRKCRRNSQPIGSVAKPAPSKYLSSYQKFLETTATTAEVEPEINSSPEPENEPKRRRTYSRACKKSTPSAKVQKITEELQINTNLDQGGKGEEGEEEEAAATAPQIPYNFLTPSQSEISSASSPNSEKSQKIHELVKQCERIAREHNSSSSSSTSSASSASSTISSISNKTRELRRHTNNRHRRSLTPVEVCDIQPTVPLNEHLLNIYDESNGGNMSPQSLSEHLESLACSLLDCDEFPDDDDRSVASTTLTGENLFESSPPSPASPRTEEEHFEFHEPREKLNKIHVMKLIELYKQQTRLWDQSHTEFCEPHLCRQSWEYITERWNAFCDRKFHITEVRIRISTLCQRYLKERERIQRNGDREENIKFPYYKELSFLEQHRSLQKRREVYEQQNDKILDIYQRHLILWHVRYYKVRQVKERNKAFQSISVELKNHGIYLSSSGVQKRIRSLRKCYRLEKIRYLRAQVEKTEFVPTFKHYAKMQFLEKHIEPFVCRLCGKIFESLPPFKDHVETSSHGNILEEEDDEELEILATTNSLASTTSPDTILCGNNGQFEISMQAGNQNSVNLFIKPLPPQGVNTISPHNQHPATLCDSTISDLPTDDQLMEGIIQTVSNDDDFVPQTLDTYVHSYEDQGDVTAFLESAANNIGNATEILTASDQQCTEDPVAVFNENLPKILGRRRSTKPKSSDVVDDECHSGDGDAQCARLSDDEIRLMISVYRRYRQLWDPNHLDYNTRSLRRQAWFSLTSEFNKILHRNFSWRSLYRKLIDYAKYYKKLVAEQSPGDIKWAFYKDLTFLDDVIGVSNEMGKSIHDRSVTLKLIEIYKDLPQLWNTRDPDYNKRPVKQRNINIVYNRLIEGTNKQISPERIKNRIIELRTQYRADKKKRIRCLNNKQKFFPDFEYYEEFNFIDAHIDPFECEFCGMDFKKLKDFNCHLRKEHEPKRRKFRGKGGDEASSSQNLDNVCHICGAKFSNRGNLGHHLIRHEGVRNFACTMCPKKFFNSHSLKIHVRSHTKECPYVCEKCGLSFVNASKLNQHVLRHTGKKDFKCDHCPKAFFTAFERDRHTRWHLNIRDKNCPICGKSFVKGSSYYAHLMLHSDTKRFKCDSCDKQFSQYAGLYKHRKRYHSP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-