Basic Information

Insect: Musca domestica
Gene Symbol: -
Assembly: GCA_000371365.1
Location: Scaffold197:65536-67278[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.04 2 8.7 0.9 3 23 113 134 111 134 0.91

2 12 0.13 6.6 7.1 0.2 6 23 145 162 145 162 0.97

3 12 0.011 0.57 10.4 8.8 1 23 168 191 168 191 0.98

4 12 0.001 0.051 13.7 0.8 2 23 233 255 232 255 0.96

5 12 0.023 1.1 9.5 0.2 6 23 265 282 265 282 0.99

6 12 0.043 2.1 8.7 6.9 1 23 288 311 288 311 0.97

7 12 0.0058 0.29 11.4 2.1 2 23 352 373 351 374 0.92

8 12 0.027 1.3 9.3 1.7 6 23 384 401 384 401 0.96

9 12 0.00072 0.036 14.2 1.8 1 23 407 430 407 430 0.95

10 12 0.0063 0.31 11.3 3.1 2 23 476 498 475 498 0.94

11 12 2.6 1.3e+02 3.0 0.8 6 23 508 525 503 525 0.97

12 12 3.3e-07 1.6e-05 24.7 3.9 1 23 531 553 531 553 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.04	2	8.7	0.9	3	23	113	134	111	134	0.91
2	12	0.13	6.6	7.1	0.2	6	23	145	162	145	162	0.97
3	12	0.011	0.57	10.4	8.8	1	23	168	191	168	191	0.98
4	12	0.001	0.051	13.7	0.8	2	23	233	255	232	255	0.96
5	12	0.023	1.1	9.5	0.2	6	23	265	282	265	282	0.99
6	12	0.043	2.1	8.7	6.9	1	23	288	311	288	311	0.97
7	12	0.0058	0.29	11.4	2.1	2	23	352	373	351	374	0.92
8	12	0.027	1.3	9.3	1.7	6	23	384	401	384	401	0.96
9	12	0.00072	0.036	14.2	1.8	1	23	407	430	407	430	0.95
10	12	0.0063	0.31	11.3	3.1	2	23	476	498	475	498	0.94
11	12	2.6	1.3e+02	3.0	0.8	6	23	508	525	503	525	0.97
12	12	3.3e-07	1.6e-05	24.7	3.9	1	23	531	553	531	553	0.99

Sequence Information

Coding Sequence: ATGAATTCCATGAAGCAGacttttggaagaaaaaataaGGTACAACAAATCAATGAGGAGCAGACAACCAAAGAACCCAGCGAAGAAAATGATCCCTTCGAAACTGATGATGATTTAAAtgatttggattttgaaattgataGCCCTCCAAAACGAACcaagttaaatttcaaaaaaatgaaaagcaaaacaaatggacgtcatcccaaacaaaatcatgaattggaaataaaCACTTCAAATCCATTAAATTCTACGGCCCTGATGCGGCCGATAAAAAGTACCCGCGAAGAAGAGCTGGACAATATTATAGCCCAATGGAAACCCGAACTGGATTGTATGGTATGTGAAAAACCATTTGCCACCTACACCCTGCTGCATGAACATTTCAAGGATCGCCATCAGCATAAACATGAATTCTATATACAATGTTGTGGTCTGAAGattaaaaaacgtggacatCTGGCCGAACACATAAGGATACACACCGATAAGAAAGCCTTCAAGTGTGCCCACTGTAAGATACGTTGTCATCGCAAACGTAATCTCGTCTATCATATGAGAAAAATACACAATATTAGTGCTAAGGAAATAGTTCCGGAAAGAGGCCTAAATCCGGAATCATCACAGATTAAATTATCCACGCAAATAATTAGGAATAACGATAGATTCATAGAACAATTTCTACCCAATTTGGAGTGCCCTCGTTGCAGGCAGATATTTCCCGTTTTTAGCAAATTGGAAAGACATTATCGGAAGCGGCATAAGGATGaggaatttcacattttatgttgTGGCTATAGGCTGACAACACAATCCCTGTTAGTAGATCATTTAAATCGGCACACTCATCCAAGGAAACAtaagtgtaaattttgtaatgccTGTTTTACGATGCAGCATGTCATGGAATATCACATGCGGGTGGATCATAAAAAGAATTCCAAAGACTCTTCAAATGACAACACTGCGGAAGATGTGGCGGATGCTCATGCGGAAGTGCTAAGCATAAAGGAAAGTGATGATTTTATATCACGATGGTTACCCAGTTTGGAGTGTCATGTTTGCAAGGAGGAATTCAAGAGCTATTCTTCGTTGGGTGAACATTTCGATGTGCACCATGCTGAGCAGCAAAGTTATGTAACATGTTGCGATCATCGATTTTTTACTCGCTCCAAACTGCAAAGGCATATCGATGGCCATATAAACAGTAAAGCATTTAAGTGTCAGCTGTGTGGCAAACGTTATACCAGAAATGAACGCTTAGAATTCCATATGGCCAAGCAACATTATGGCACAATTTCATCTGTGACCAGTTATTGTGAAGATCAGCCCAGCCCTGGGACAGAAACGCAAAATGTCTTAACGAAAAGAAAATCCCTTAAAGATCTTGATCGTACCATAGCCCAATGGAAACCTAAACTAGAGTGCCGAGTGTGTCATAAAACCTATGCAACTTTTACATTATTCAGCCGGCACTATCGTGACACACATCCCGCAGAACAATGTTATATCTCCTGTTGTGGCTGTAAATTTGCTGGCCGTTATGATATTGTCGAACACATCAAATATCACAGAGATCCAAATGCATTTAAATGCACCCAGTGTGGGCGTTGTTTTAATCGCAATCGTGGTCTGATATTGCACATGCGAACTCATcgaaattaa
Protein Sequence: MNSMKQTFGRKNKVQQINEEQTTKEPSEENDPFETDDDLNDLDFEIDSPPKRTKLNFKKMKSKTNGRHPKQNHELEINTSNPLNSTALMRPIKSTREEELDNIIAQWKPELDCMVCEKPFATYTLLHEHFKDRHQHKHEFYIQCCGLKIKKRGHLAEHIRIHTDKKAFKCAHCKIRCHRKRNLVYHMRKIHNISAKEIVPERGLNPESSQIKLSTQIIRNNDRFIEQFLPNLECPRCRQIFPVFSKLERHYRKRHKDEEFHILCCGYRLTTQSLLVDHLNRHTHPRKHKCKFCNACFTMQHVMEYHMRVDHKKNSKDSSNDNTAEDVADAHAEVLSIKESDDFISRWLPSLECHVCKEEFKSYSSLGEHFDVHHAEQQSYVTCCDHRFFTRSKLQRHIDGHINSKAFKCQLCGKRYTRNERLEFHMAKQHYGTISSVTSYCEDQPSPGTETQNVLTKRKSLKDLDRTIAQWKPKLECRVCHKTYATFTLFSRHYRDTHPAEQCYISCCGCKFAGRYDIVEHIKYHRDPNAFKCTQCGRCFNRNRGLILHMRTHRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -