Mdom009918.1
Basic Information
- Insect
- Musca domestica
- Gene Symbol
- zfh1
- Assembly
- GCA_000371365.1
- Location
- Scaffold4455:283970-328265[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.27 14 6.1 0.3 2 23 85 107 84 107 0.95 2 9 0.042 2.1 8.7 3.7 1 23 324 346 324 346 0.98 3 9 5e-05 0.0025 17.9 1.7 2 23 362 383 361 383 0.97 4 9 1.4e-05 0.0007 19.6 6.4 1 23 392 414 392 414 0.99 5 9 0.00041 0.02 15.0 1.2 3 21 422 440 420 441 0.94 6 9 0.0012 0.058 13.6 0.7 2 21 750 769 749 770 0.92 7 9 3.2e-05 0.0016 18.5 0.5 1 23 1179 1201 1179 1201 0.94 8 9 6.9e-05 0.0034 17.4 7.4 1 23 1207 1229 1207 1229 0.98 9 9 0.0035 0.17 12.1 4.3 1 21 1235 1255 1235 1256 0.96
Sequence Information
- Coding Sequence
- ATGTTGTCGTGTTTGGTGCCGTCGTCAACATCACGTTTTGGTCAAGAGGataatattataaatcaaagtATGCCCTCATCGCCAGCATTCACCATGCAATTTCCTTCATTGACCTCCACattacatcatcatcatcagtcaAAAAGCAGTAGTGCCGGCAGCACCACTGTCGATGATGAAAACTCCAATGGTGCCCCAGCTTcatcgttgggcgccacttcgcCAACACCACAACAGACGGACTTTATGGTTACATGTCCACAGTGCCATGTGAGATTAAATGGCTTTGAGTCCCTGCGCGATCACATTGCCAGCCAACATCcacatgacaaacttaatattgaaCCCTCCTATCCCAGTCCGCCAGCTGATCGTGAGCACTTGAATCAAACGACTGGCGAAAATGTCGCAGCAAACACAAATACCGTCGACAGTGATGACAGTAATCAAAGTTCAAGTGAATCGAAAATgttcaataacaacaataacaatagtcAAGAAAAGAATAACAATAGTATTAATGACACACCCAGCCATCATAACAATCCTTCCGCCCCCAATACACCACCACCCTCAGTAGTTGGTGGACACCAGCAACAGCATAACACCACCAATGGACTAGGAGATTTATCTACATCTCCCTTTGCCAGTCATTTGCCTCACAATTTGCATCCAGCAGCTGCCGCCCAATTCATGGCTGCCCTGGccatgcagcagcagcaacaccaacaacaaaattctgGCAATACTTCACCCACATCCCATTTATTAGGTGGCTTCAATGGTCATCACAATCTGCCtacacatcatcatcatcatcatccacatcatGCATTGGTCGCCGCCGGTCAGCAACATTCTTCGTCGTTCGTCGATAACGCAACCATGGATACAATGCGTTCCACCTCCAGTCCCGGTTCCTGTGGTGGCAGTGATAACAATTCGGCAGCCAGCAGTATAAGTCCACCGTATCAGTGTATGCACTGTACGGCATTGTTTCAGACACGTCATGAACTGGAGAAACATGAACTAATGCATTCACCCAATGCGCAATCGCCACAGTCGCTGAATGGTGTTAATCAAAGTTGCAAAATATGCCACAAAGCTTTTGCCAATGTCTATCGCCTGCAACGTCACATGATTAGCCACGATGAGTCGGCTTTATTGCGCAAATTCAAGTGTAATCAATGTGATAAGGCCTTCAAGTTTAAGCATCACCTCAAGGAACATGTGCGCATACATTCCGGCGAAAAGCCATTTGGTTGTGATAACTGTGGCAAACGTTTCTCGCATTCCGGCTCCTTCTCATCGCACATGACCTCCAAGAAATGTATTAGCATGGGTCTGAAGCTCAATAACAGTCGTAATCATTTGAAATCCGCCAACGCATCACCGAACAGTCTTAAAATATCCTCGCCAAATGGTAAAAGTGATGCAGCCAATAACATTGTCAACAACTTAACCAATCCCATGAACTATTTTGCTGGGGATTCAAGTGCTGCTGCCGCCGGCACCCCTCCAACCAATCCATTCTATTCAAATTTGCTACCCAAATATGGTGATTATAATAGTGCCATGAATGCTGCCCTACTAGCATCATTCCCCAATCCATTCTATAGCATGGCATTGGATCCGCGTATACACCCATATAGTATACAACGTTTATTGGAATTGACTGCTGCTggacagcagcaacagcataaCAATCAGGAGTCCGAACAACAGTCTCAAACActaacaccaccaccacaattCGGCCATCAAAATGATGAGGCTGAGGAAGAAGAGGAAAATAGcaaagatttgaaaatttccaacagCAGTAATGCCGATGAAGAAGAAGACATACACTCAGAAACTTTGGACCTAAATGAAGAAGATAATCTGGACGAACCAAAATTGGTAATGGATTTGGAGGCCAGCGAAGGGGATAACAAGGAAACCGAACAGAACACCTCAATCAACAgtcaagaaaatgaaaatgaagttAAAGAATCTCACCAAGAAACACAAGAAAACGAAGAATTTGAGGCATCACAAAAATCAGAACTCAATACCAAATCCATTAAACAGGAACAAACTGAAAGTCGTGATGCCCCGGAATCTCCGGTAAATATTACCACACAAATTAAACAGGAAAACCTGGAAGAATCTGAAGAGCAATTAGAAATCGCTGAAAAGGAAGAGGAATCGGTAGAAGTGGAAAAGCCCTCCGAAGATCAGAATAATAGCTCAATTGCCGAACTACGTTGCAGCCGTTGTGATAAGAAATTTAATCATCCCACAGAATTGGTACAACACGAAAAGGTATTATGTGGCTTTATTAAACAGGAATTGGAGCAACaatatcagcagcagcagcaacaagttTTGGACCAATCCCAAAACTCCAGCTCCTTTATGGCTGCTAGTGATGTTGAAGATGAGCAGGATGAACGTGATTCAATTTCACGTAATGATTGTTCCAGTGGCGGGGAAAGTAATGCCGAACGTAAGGTCCGTGTTCGCACTGCCATTACCGAGGAACAGCAGCAACATCTCAAGCAACATTATGCCATCAATTCCCGACCGAGTCGTGAAGAATTCCGTTTGATTGCCTCTCGTTTGCAACTTGATGCTCGCGTTGTACAGGTGTGGTTCCAAAATAATCGCTCGCGTGAACGTAAAATGcaatataacaacattaacaataataacaataacctGAAAGCTGCATTCCCCTTGCCCCCGTTGCCACCAATGGCTGGCACAGGACAAACGCAAAATTTCGAAGAAGCTCCTTTAAGCAAACCTGTTACAAATTCCGAAGAGTTGCCATTGGATTTATCGGTGAAGCCTCAACGAAATTCCGGTAATGGTCAACAGCAACATTCTCCGTTATATGGTATTGCTCCACTGCAGACAGCAAATGCCAATGTGGCTGGAGATTTGGCCGAAGCCATTAATCTAAGCCGCAAAATGTCACCGCCCACCTCATTATCGCCCAACTCTGCTGCCTCCGTGCCAGCAGTTTTCAAGCAACAAGCTCAAGCTgcagctgctgccgctgctcTCTATTTTGCAGCACCCTCGCAGGCAAATGGTGCACCCAACTTACCTCACAATATGCGCCAGACGCCCTCACCCATTGAGGCTCCGCTCTTGGGTCCCCAACAGACTTCAACGCCACGTGGTGCTGCTGCATTCCCTTCATTCTCTCAATTACCTCCATACATGATGCCCGCTGCCATGGCAGCTGCCCAGCGCAGTCTTATGCCCATGGAAGCTTTATTTCAAATGACACCCGGCTCAGCAGACTATGCCCGTCAACATCCGCTAATGAACAGTATTAAAATGGGTCCCACTCTCGACTTCAGAGGCAACAGTCTAAGTCCTAACTCCGAGAAACGTTCATGGCGTGATGATGATTCACGGATATCACATGAAGATGAATACGCCCACGCTCAGGCCCAAGCGGCGGCCGCACTTATGCCACCCAAACCCAAGCGGGCCAAGGCCGAGACCCATGGCCATGCCGGTGATCCTGATTTGCCTTTCATTTGTGATCAATGTGATAAAGCATTTGCTAAACAAAGCTCGCTGGCGAGACATAAGTATGAGCATTCCGGCCAACGTCCCTATCAGTGCATGGACTGTCCCAAGGCTTTCAAGCACAAGCATCATTTGACGGAACACAAACGTTTGCATAGCGGCGAAAAGCCCTTCCAATGTTCCAAGTGCCTAAAACGTTTCTCACATTCCGGCTCCTATTCACAGCACATGAACCACCGTTACTCCTACTGCAAACCATACAGGGAATAG
- Protein Sequence
- MLSCLVPSSTSRFGQEDNIINQSMPSSPAFTMQFPSLTSTLHHHHQSKSSSAGSTTVDDENSNGAPASSLGATSPTPQQTDFMVTCPQCHVRLNGFESLRDHIASQHPHDKLNIEPSYPSPPADREHLNQTTGENVAANTNTVDSDDSNQSSSESKMFNNNNNNSQEKNNNSINDTPSHHNNPSAPNTPPPSVVGGHQQQHNTTNGLGDLSTSPFASHLPHNLHPAAAAQFMAALAMQQQQHQQQNSGNTSPTSHLLGGFNGHHNLPTHHHHHHPHHALVAAGQQHSSSFVDNATMDTMRSTSSPGSCGGSDNNSAASSISPPYQCMHCTALFQTRHELEKHELMHSPNAQSPQSLNGVNQSCKICHKAFANVYRLQRHMISHDESALLRKFKCNQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNSRNHLKSANASPNSLKISSPNGKSDAANNIVNNLTNPMNYFAGDSSAAAAGTPPTNPFYSNLLPKYGDYNSAMNAALLASFPNPFYSMALDPRIHPYSIQRLLELTAAGQQQQHNNQESEQQSQTLTPPPQFGHQNDEAEEEEENSKDLKISNSSNADEEEDIHSETLDLNEEDNLDEPKLVMDLEASEGDNKETEQNTSINSQENENEVKESHQETQENEEFEASQKSELNTKSIKQEQTESRDAPESPVNITTQIKQENLEESEEQLEIAEKEEESVEVEKPSEDQNNSSIAELRCSRCDKKFNHPTELVQHEKVLCGFIKQELEQQYQQQQQQVLDQSQNSSSFMAASDVEDEQDERDSISRNDCSSGGESNAERKVRVRTAITEEQQQHLKQHYAINSRPSREEFRLIASRLQLDARVVQVWFQNNRSRERKMQYNNINNNNNNLKAAFPLPPLPPMAGTGQTQNFEEAPLSKPVTNSEELPLDLSVKPQRNSGNGQQQHSPLYGIAPLQTANANVAGDLAEAINLSRKMSPPTSLSPNSAASVPAVFKQQAQAAAAAAALYFAAPSQANGAPNLPHNMRQTPSPIEAPLLGPQQTSTPRGAAAFPSFSQLPPYMMPAAMAAAQRSLMPMEALFQMTPGSADYARQHPLMNSIKMGPTLDFRGNSLSPNSEKRSWRDDDSRISHEDEYAHAQAQAAAALMPPKPKRAKAETHGHAGDPDLPFICDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01019333;
- 90% Identity
- iTF_01019333;
- 80% Identity
- iTF_01019333;