Basic Information

Insect: Musca domestica
Gene Symbol: -
Assembly: GCA_000371365.1
Location: Scaffold19318:139025-141454[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0025 0.12 12.5 5.7 2 23 355 376 354 376 0.97

2 11 0.00018 0.009 16.1 1.6 1 23 382 406 382 406 0.96

3 11 0.56 28 5.1 1.5 1 23 413 438 413 438 0.96

4 11 0.00013 0.0064 16.6 0.1 1 23 447 469 447 469 0.96

5 11 0.03 1.5 9.1 1.7 1 23 477 501 477 501 0.96

6 11 0.011 0.54 10.5 1.5 1 23 507 529 507 529 0.96

7 11 0.0027 0.13 12.4 0.9 1 23 535 558 535 558 0.94

8 11 9.8 4.8e+02 1.2 1.5 1 23 569 591 569 591 0.79

9 11 7.7e-07 3.8e-05 23.6 0.2 1 23 597 619 597 619 0.98

10 11 1.9e-05 0.00094 19.2 0.9 1 23 626 648 626 648 0.98

11 11 0.00033 0.016 15.3 1.6 1 23 655 677 655 677 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0025	0.12	12.5	5.7	2	23	355	376	354	376	0.97
2	11	0.00018	0.009	16.1	1.6	1	23	382	406	382	406	0.96
3	11	0.56	28	5.1	1.5	1	23	413	438	413	438	0.96
4	11	0.00013	0.0064	16.6	0.1	1	23	447	469	447	469	0.96
5	11	0.03	1.5	9.1	1.7	1	23	477	501	477	501	0.96
6	11	0.011	0.54	10.5	1.5	1	23	507	529	507	529	0.96
7	11	0.0027	0.13	12.4	0.9	1	23	535	558	535	558	0.94
8	11	9.8	4.8e+02	1.2	1.5	1	23	569	591	569	591	0.79
9	11	7.7e-07	3.8e-05	23.6	0.2	1	23	597	619	597	619	0.98
10	11	1.9e-05	0.00094	19.2	0.9	1	23	626	648	626	648	0.98
11	11	0.00033	0.016	15.3	1.6	1	23	655	677	655	677	0.98

Sequence Information

Coding Sequence: ATGGCTGAAAATGACTTGTTGAACGAGTCCATAGTGGAGgaagtgaaaaaatatgaagtCCTATACAACAAAGCACACCCACATCATGGCAAGAGTGGGGTAACACAACAAACATGGAACAAAATTTCCAATGTGGTGGGAGTCACTGtcCAGGAATGCAAATCCTTGTGGGTTGCATTGAAAAGGGGCTACATCTCTGAATATGAAAAGCTGAGGGAAAACAATAATTTGGAGAAATGCAActcaaattggaaatattttgaagccATGTCATTTCTGAGTGGCCATATTGACCCTGATCGAAATTCCATGGAAAACCTTGAACATCTGCCTGGAAGAGATGCTTTTTGTCGAGCTTGCATGGCCAATCTTAATGAAGCTTCTGATGACCCCACTTCTGTCCCAAATTACAACATTTTCAGTTCAAATATTCAACTGGACAAGAAAATAATGCAATGTACGAATTTTGAATGTTCACCCTGGGATGGGTATTCCCATGTCGTTTGCCACCATTGCTATGTTAAAATTCTAGATTTCTATGATTTTCAATGTGTGTACCGCTCGTCAATGGAAAAATTCAAGGTGTTACTTGAAAACGAACTAGATTTTAAAGACGAGGATGATGAGAAAATGTCCACAATTTCTTCTGTGGAATGTGATAATAATTCATTTCAGAttaatgaagaaaatatatatcacgAGGATGTCCATGCCGATAATATATCTGGGACGGCAGAAGATCCCTTAAATTCGGAAGATTTTGCAAACACACAAGATGTGAAAAATGAGAAATCAAGCAAATCGCCAAAACAAGAATTTGAAATCAAGGAAATTGGTTTAAAAACCAGGGAAGTACGAAGTACAAAGCTTAGCCCAAGAAGAAGTGGTCGGAAGAGAAAACTTCATGCTAGCAAAGAGGAAGATAATTCTACATCTGataatgaaataaattcaattgaGGATTTACATCACAGatcagatgatgatgatgaacagtcaatttccaatttttcatcCCAATCAGAAGATGCAGAGGAAGAAGTCACCAAAAAGCCAATacttaaatgtgaaatttgtgaGAAACAATTTCGTTTTCATCATCGTCTGGAAGCGCATAGACGAAAACATGAAGGGTTGCCAGGCTATCCTTGTACATTTGAAAACTGTCAACGTGCCTTTAATCGCTTGGATCACTTGAGAAGCCATCTGAACGAACACAATGGCATACCAAATGTTTTTCAATGCAACATTGATGATTGCCTAATGGAATACAAATGTCTCTCGGGCCTGAACAAGCATAAACGAAGTGTGCATAAATGTGgcaaagaattgaaaaaatatccctgTGATATATGCGGCAAAGTCTTGACGAACCCGCGATCCCTGAATGGCCATAAGTTTATACATGTCGACAAATCGGAATGGCCCTTTGTGTGCGATGTTAAGAATTGTTTGCGCAAGTTCCGCTTAATGTCCCAGCTGACAATACACAAGAAGCGCCATGCGGGCATTAAGAATTACATATGTCCATATTGTGGGGTACGCAAGACCACCTGCACTGAACTTAAGATACATATTAATTTCCATACCTTTGAACAAAAATATCCCTGTGAATATTGTTCGAAAGTTTTCAAAAGTGTTGGTGTGATGAGGACACATGTCCACCGTGTCCACGAGGGAAAGAAACCGGCAAACTATAAAATGTTTTCCTGTGATTTTTGTGATGGCAAATTTGCTTCATTGCAAACGAAAAAATTCCATGAAATGACCCACAGAGGTGAAAAGCCCTTCAGTTGTGAAGAGTGTGGCAAAACGTTTACTTATCCCTCGGGTTTGGCATCACATAAAAATGTCCATGCCAAGGGTGAAAATCAGTATGTATGTAAGATATGTGGTCGTAAATTTAAATGGCAATCTGGTTTGAAAACCCATTTGAAATTACACACCGAAGCGGCAAAGCCATATTCGTGTAAGGAATGTGATAAAAGTTTTCGTTGGCCGGGATCGTATTATAAACATAAGAAAGTTCACATGCGCCAGGAGGAAGAGAGCGTGGAGCCGGAAAATATAAGCCCAACAAATCACAATGATGATGGACCTGAGCTGGGCCAGGAAAATGAAACACAGGCACCTGTTGAGTCACCAAAGTATGAAATTATATATGCAACCATTGATGTGGACACAAATAAAATGGGGTAG
Protein Sequence: MAENDLLNESIVEEVKKYEVLYNKAHPHHGKSGVTQQTWNKISNVVGVTVQECKSLWVALKRGYISEYEKLRENNNLEKCNSNWKYFEAMSFLSGHIDPDRNSMENLEHLPGRDAFCRACMANLNEASDDPTSVPNYNIFSSNIQLDKKIMQCTNFECSPWDGYSHVVCHHCYVKILDFYDFQCVYRSSMEKFKVLLENELDFKDEDDEKMSTISSVECDNNSFQINEENIYHEDVHADNISGTAEDPLNSEDFANTQDVKNEKSSKSPKQEFEIKEIGLKTREVRSTKLSPRRSGRKRKLHASKEEDNSTSDNEINSIEDLHHRSDDDDEQSISNFSSQSEDAEEEVTKKPILKCEICEKQFRFHHRLEAHRRKHEGLPGYPCTFENCQRAFNRLDHLRSHLNEHNGIPNVFQCNIDDCLMEYKCLSGLNKHKRSVHKCGKELKKYPCDICGKVLTNPRSLNGHKFIHVDKSEWPFVCDVKNCLRKFRLMSQLTIHKKRHAGIKNYICPYCGVRKTTCTELKIHINFHTFEQKYPCEYCSKVFKSVGVMRTHVHRVHEGKKPANYKMFSCDFCDGKFASLQTKKFHEMTHRGEKPFSCEECGKTFTYPSGLASHKNVHAKGENQYVCKICGRKFKWQSGLKTHLKLHTEAAKPYSCKECDKSFRWPGSYYKHKKVHMRQEEESVEPENISPTNHNDDGPELGQENETQAPVESPKYEIIYATIDVDTNKMG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -