Basic Information

Insect: Musca domestica
Gene Symbol: -
Assembly: GCA_000371365.1
Location: Scaffold20412:71028-73933[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.016 0.78 10.0 4.4 2 23 272 294 271 294 0.91

2 10 2 97 3.4 0.3 6 23 303 320 303 320 0.93

3 10 0.00013 0.0064 16.6 1.7 1 23 326 348 326 348 0.99

4 10 0.00092 0.046 13.9 3.8 1 23 353 375 353 375 0.97

5 10 0.00041 0.02 15.0 0.2 1 23 383 406 383 406 0.95

6 10 1.5e-05 0.00075 19.5 0.9 2 23 413 434 412 434 0.97

7 10 0.072 3.6 7.9 2.8 2 23 444 466 444 466 0.92

8 10 0.0022 0.11 12.7 2.5 1 23 473 496 473 496 0.94

9 10 2.5e-07 1.2e-05 25.1 0.9 1 23 502 524 502 524 0.98

10 10 8.5e-05 0.0042 17.2 3.1 1 23 530 553 530 553 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.016	0.78	10.0	4.4	2	23	272	294	271	294	0.91
2	10	2	97	3.4	0.3	6	23	303	320	303	320	0.93
3	10	0.00013	0.0064	16.6	1.7	1	23	326	348	326	348	0.99
4	10	0.00092	0.046	13.9	3.8	1	23	353	375	353	375	0.97
5	10	0.00041	0.02	15.0	0.2	1	23	383	406	383	406	0.95
6	10	1.5e-05	0.00075	19.5	0.9	2	23	413	434	412	434	0.97
7	10	0.072	3.6	7.9	2.8	2	23	444	466	444	466	0.92
8	10	0.0022	0.11	12.7	2.5	1	23	473	496	473	496	0.94
9	10	2.5e-07	1.2e-05	25.1	0.9	1	23	502	524	502	524	0.98
10	10	8.5e-05	0.0042	17.2	3.1	1	23	530	553	530	553	0.97

Sequence Information

Coding Sequence: ATGGAGTGTTTATTGTGTTTGGAAACGAAACAGGAGAACGAATCAAGATATATTAAAGTTGATTCAAGTCAATGGGAAGAATTGAATATCAAGAACCTAATCGATAAACATCTCTGGCCCATAGAATCCCTTTTACCGACATCTTGCGTTTGCGACACATGCTGGGAAGAACTATATGATTTCCACAAATTCTACATACGCATAGAACAAACACATAATGACAATAAACTAGCACTGAAATCCGAAGCTGATCCCTTACAAGATGAGTCGAAGCCAAAAGATGTCTTATTGAAAAGTCTGCTAGAACCAGAAATAGTTattggtcaacatttagatGAACCCATTGAAATTAAACAGGAGCATGATGAACCTATTGCGGTCATTTTGAAACGCAATGATGATGTTGGGGATGTGGAAAACAAACAAGATATTTCTGAAAATTCTggcgatatttttgaaaatgaacaGGATCCAATGGAATTTATTGATAACAACAGTGATTCCAATTTTAGCGATAATGATGGTGAAGAGGATGACCACACAGATAGTGATGATGATTTACCTTTAATACAcaaagtaaaaatccagcaaagcaaaaaatcatcaaagaaaaacaataaaacaaaagatgTTGACAATGAGGATCATGAAGAAAAGCACGGAGACAATggcaaaaaacgaaagaaaaaattggcaaaatccacaaaaaagagCACTTCGTGCTCCAAACGATCCACAAATCGTCAAACTTCCACACTTCCAAAAATCAATCGTGTAGAGTATGATAAATTCCTACAGGAACACTTTAAGATGACATGTGACAAATGTCAGAAAACATTTGAACGTTTCCGTTTGCTTTGCCAACATTTTAGCCAGGAGCACAACGAACAGGGCTATGTCATGTGTTGTGCCACGAAATTCTTTAATCGCCGTCTTCTGGTGGATCACATCAATTATCACCTTGATCCGGAGTATTTTAAGTGCAATCTCTGTGGGAAAGTCCTAACCAAACGCATATGTCTTATTGGTCATATGAAAATGCatgaagaaaagaaatttgcTTGTGATAAGTGCGACAAGAAATTCGTGCTAAAACATAAGCTAGACAAACATAAGTTAACACATCTGCCGGAGTCGGAGAAGAAGTTCCCCTGCAATGATTGTGGTAAATTTTACGCCAACGAATATATACTTAATCAACATCAAAAGGCCGTTCATCTCAATATATATGCTAAAGTGTGTGAAatatgtggcgaaacattacccGATTCGCATAACTTCAAAAGGCACATGGAAAAGCACGAAGGCATTGTGCCGGTTAAAACAGCCAAGTGTGATATATGTGGTCTAATACTCACTAGTCATCACACGTTAAAGCTGCACAAAGAACTGAAACATCCGCCGGAGAGGCGTGAATATAACTGTCATATCTGTTCTAAGGTTTCACCTAATATGCGTGCACTCAAGAAACACATACATGAAACCCATGAAATGGGCTATCGTTTTAAGTGTACAATTTGTGAAAAGGAATTCAAAAGAGCTGATAATTTTAAGTCCCACATGGCTATACATACTGGCAAGCCTCTGCATCGATGTCCCTGGTGTCCTAAAGAGTTTAATTCTAATGGCAATATGCATCAACATCGCAAAAAAGCCCACCCTGTTGAATGGGAGGAGGCACAACGCAAGAAATATTCCGGAAATTTACCGCCTAATTATAAAAGACCAACACCCGCGGCGACAGTCAGCAATAGTAACAATAATTCCGTATTACCAGCCACAGTAAATCAAGTACCAtcataa
Protein Sequence: MECLLCLETKQENESRYIKVDSSQWEELNIKNLIDKHLWPIESLLPTSCVCDTCWEELYDFHKFYIRIEQTHNDNKLALKSEADPLQDESKPKDVLLKSLLEPEIVIGQHLDEPIEIKQEHDEPIAVILKRNDDVGDVENKQDISENSGDIFENEQDPMEFIDNNSDSNFSDNDGEEDDHTDSDDDLPLIHKVKIQQSKKSSKKNNKTKDVDNEDHEEKHGDNGKKRKKKLAKSTKKSTSCSKRSTNRQTSTLPKINRVEYDKFLQEHFKMTCDKCQKTFERFRLLCQHFSQEHNEQGYVMCCATKFFNRRLLVDHINYHLDPEYFKCNLCGKVLTKRICLIGHMKMHEEKKFACDKCDKKFVLKHKLDKHKLTHLPESEKKFPCNDCGKFYANEYILNQHQKAVHLNIYAKVCEICGETLPDSHNFKRHMEKHEGIVPVKTAKCDICGLILTSHHTLKLHKELKHPPERREYNCHICSKVSPNMRALKKHIHETHEMGYRFKCTICEKEFKRADNFKSHMAIHTGKPLHRCPWCPKEFNSNGNMHQHRKKAHPVEWEEAQRKKYSGNLPPNYKRPTPAATVSNSNNNSVLPATVNQVPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01019644;
90% Identity: -
80% Identity: -