Basic Information

Insect: Musca domestica
Gene Symbol: -
Assembly: GCA_000371365.1
Location: Scaffold20357:15331-25154[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.22 11 6.4 1.3 1 21 1592 1612 1592 1615 0.90

2 12 2.3 1.1e+02 3.2 0.7 1 23 1774 1796 1774 1796 0.93

3 12 0.00059 0.029 14.5 2.8 2 23 1799 1820 1799 1820 0.97

4 12 2.8e-05 0.0014 18.6 0.2 3 23 1828 1848 1826 1848 0.98

5 12 3.2e-06 0.00016 21.6 5.8 2 23 1855 1876 1854 1876 0.97

6 12 6.6 3.3e+02 1.8 0.1 5 23 1889 1907 1888 1907 0.96

7 12 0.028 1.4 9.2 0.1 2 23 1946 1966 1945 1966 0.96

8 12 6.9e-05 0.0034 17.4 0.4 1 19 1972 1990 1972 1994 0.95

9 12 3.9e-06 0.00019 21.4 1.8 1 23 2002 2024 2002 2024 0.99

10 12 0.00014 0.0068 16.5 6.5 1 23 2030 2052 2030 2053 0.96

11 12 0.00083 0.041 14.0 6.4 1 23 2058 2080 2058 2080 0.99

12 12 0.0021 0.1 12.8 6.0 1 23 2086 2108 2086 2109 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.22	11	6.4	1.3	1	21	1592	1612	1592	1615	0.90
2	12	2.3	1.1e+02	3.2	0.7	1	23	1774	1796	1774	1796	0.93
3	12	0.00059	0.029	14.5	2.8	2	23	1799	1820	1799	1820	0.97
4	12	2.8e-05	0.0014	18.6	0.2	3	23	1828	1848	1826	1848	0.98
5	12	3.2e-06	0.00016	21.6	5.8	2	23	1855	1876	1854	1876	0.97
6	12	6.6	3.3e+02	1.8	0.1	5	23	1889	1907	1888	1907	0.96
7	12	0.028	1.4	9.2	0.1	2	23	1946	1966	1945	1966	0.96
8	12	6.9e-05	0.0034	17.4	0.4	1	19	1972	1990	1972	1994	0.95
9	12	3.9e-06	0.00019	21.4	1.8	1	23	2002	2024	2002	2024	0.99
10	12	0.00014	0.0068	16.5	6.5	1	23	2030	2052	2030	2053	0.96
11	12	0.00083	0.041	14.0	6.4	1	23	2058	2080	2058	2080	0.99
12	12	0.0021	0.1	12.8	6.0	1	23	2086	2108	2086	2109	0.96

Sequence Information

Coding Sequence: ATGGGGGAGAACGTTCAATGTCCGGTATGCACTTTATACCTGCACGCAGGTATGAATCTCTCTGATCACTTGGAGACGCATCCGAAGGAGCAGGTGATAAGAGCATTAGTACAAATGACCATCTCCGGTGGCAGTGGAGGGGGTACAGCTGCATTGGCATCAGTGTTGAAGGGTACATGTAGCAACAGCGCCGAAAATAATAAATCTCCCAGTGAACAGGAGGAGAAATCTATCTCGTCaaatgataaaattattgaatcaAATATAGCTAGCACCAGTAACAGCTGTAACGCAAGCATAAGTAGTTCAGCAAGTAATTGCTCGCTTTCAAACCAAAGCAATACAACAAGCCAAAATTCAAACAacgttttaaatttttcgaataCCAGCATTGCTGACAATAGTAGGAGTGAGTCGCAAACACCTTGTAAATCGGCGTTGAAGTTAGAAGAAGCACCTGTCGCGAGTAAAGATCAAAGTGGTAAGGAGGCCACAAGTGAAGTATACGTTCATTCACATCGGCCCTACACTAGCTCGTCAAATGATGTACCAGCTAATACAGATCCTAATTTCGGTATATTTGGTAATCCACGTTTTCAAAACCAACATCGTACTGTGGGAAGCCAGCAGCACCAACAAATGCCGCCCCCTCCAGCGCCCCAGGGACAACACGGAGAGATTCCACGCACAATTTTACCACCGCCTCCACCGATGCCTCAGAGTATGTCATCTCAGTCAATACAAACCGTATTTCAATCAATACAGGCCCAGCAGTTGTCAAatagccaacaacaacatcacagtTCGCATGCTCGACAGCCCCATATTTACACCTCTCAACATCATCAGCACCCACCTCAACACCAGCAGGATATGAAAGTCATTTATGCCTCAGGTttaccaccgccaccaccactccagCTTTTCAGTAGTTACCAGCAACCATCTCAATTGCAACACCATCACCAAAAACCGCCACCAGCATATGGAACAGCCATTAGTCAAATCAGATCTCAGAACAAACACCAACTAAACGGCCAGTTTGCTGGACAGCATCATCACACATCCATTACTTCAAACGCAGATGCAATACTGCATCAACAACATCATTTGCATCAGCAGCAGGCAACACATCCCCATCATATTAGAATGCATGGCAACGTGGCGCATCAACTACATCCTATAgccacaaaacatttgttttctaAAACAAATGACATTCCCCAAACAACATCTTCAACTCTCTCATCTCAAACTACATCGAGACAAAGTAGCAATGTTCACCAGCAACATCaacatggaaaatatattttaccttCGCTTCAACAACAACCAATTAGTGTAGAAAATTCAGCTCTATATAACAATTGTCCAACTGCAAACGACAGTCAAGAAAAAACGATAAAAGCATCAACGGCGAATGGAAGTGGTTCGGCTGCACATATTTCGCATTCAGCACAACCAAATGTAGGAATCAATCCGGCCGTAGCTTCAGCTTCAATGGCTGTTGTTACAGCTTCGACATTGAATCGTCCCACTAATTCGCCATTTGCAGCATTATTAGCGGCAGCATCGCCTTCCGCAGCATCATCTGTATTAAGATATGCTGAATCTCCGGTAGCACATTACTTGGAAAGGGATAACGGCGACTTTATTGTACAGGAAACACCTAAACATATTGTAGAATGTGTTGAAAAAGATAACGGAGAGTTTTCTGTAATTGAACGCATCTACCAATCCCCACCTAGCGTTTTACATATTCATGACGATGCAGATGATGACGAAGAAGACGATGATAAAACTGGAAGTTCGGCAAATGGAAATAACACCCCTACCTGTACTAATGAGGTTATTGTTAAGGATTCAAAAGAAGAAGCCAAGGATGCTAATATTAAGCATCCGAAAAAGAAAATCTCATCCCAATCGACCAAGAATGACAACAATTCCCAAACggcaaatacaaataaaatgtcAATTGACTCTAAGGCTCAGAGTAGAAAATTAAAGCACTTCGAAAGTTCAACGTCATCAGATAATGAGGTTGAAGATTTCGTTAGTATTTCGAGCGATAGTGACGAGGAGGAGTTTATTTCACACGAAAGAAATGGTCAGACGAACAAAAATACCACCGAAAAGATAAAGAAAAATCAATCAGATCAAACTCTGCCTCCAACACCATCAACATCAGCATCTGCACCAAGGTTACAACATCCATCTCCCACGAACTTAGAGACACATTCGGCTACCGCTGTGTCCACGTCAAATGCATCAAATAGTACATCAACAGTTCACCAAAACAGCAACACGACTCgcaaaaaatcgtcgaaaaatacaaTTACCGTTTTAAGTGATGTACAACTGAACTTGAATGAATATTtagatttggttggaaatataATAGCCTCCAGCAAAGTTGCCGCACAGCGCAGAACTTTAACGGCAATTGCGCCAATACCGTTGGTGAAAATTGAAAAGGAAGAGCCAATGGACGATTACGCAACGACGCCGGCTGATACTGCAGAACAACACACACTACCACCTACACCATTAAAGGCCAACAAACAAGAGACTGAAGAATTAACTGATAATCCTAGCTGTAGTAGTACTAATAATAAAAGCAGTAAAATAAGCTTAACAGATCAAACAGTACTGGAAAAGGACGAGAAAAAACCTCAGATTTTAGAGAATAATTCAGATAGTAGTAAAATAATATCGTCATTAATACCAAACTCCAGTCAAGTCACCAGTGTTATACGTATGGCAACCACTAGTCTacaacaatcacaacaacaacaacaacaacaaaattcacaGCAATCCATAGTTAGATCAAATGAAAACACTTCAGATAGCAATGAGAGTAAAACTGAGGCGGAAGATCTATCCCAACATCAGCGGAATTTGCCTATTACTGGACAGAACAAAACCACCTCATTAGGGTTACCAACATTGGGACGCAAAGGCCCTAAGAAACTCGTTATTAAGCCAAAATCTTCCAAGACTTCATCTAACGATTTTCACTTTGATGACCAACAACCATCGACATCTGCCAAAGCTTTAGAAGAATACAATAAATTATCGCTGCGAACTCAAGAAAAATCTGTCAACGAGCCAGAAGTTCAGGTTAAAAATGAACCCCTAACTTCCATAGCATTTGAAAGTAATCAGTATACTCAACCAACTGGTTACAGCAGTATTTTGGAACAGCAGCTGACTTCGAAAGAGCCTATTATGCTGTGCAAGGAGGAAAAGCCGTGTATCCAGGAAACAAATGTTCCTACCGATGTAAAAGATATGAAAGTTGAAAATAATGTGAATGAGGATGCACGGGTCTTATATGATTTTGCAACTTCaaaaaaaGGACAAGCTAGTTCGAAACCGTCAACATTTCCGTCACCATCatctttattttccaaaaatcagaCAGTAAATCAAAAGGATAAGGAGAATGTTTCGGAATCCAAGGTTTGTAATTTACATTCGACAAATGAGGCACAGTTGGTACACTCATCACATCTGGAAGCAACAAGTAAAAACGGAGAGGTGCAGAATAAAGCTTCGACAGCTTCTTCAAGCGATAATAACGATTGCTCTGAAATATTTCCTGATTTTCCGTTTAACTAtctcaataacaataacaatagccATATCAGCACTAACGACCAAACAGTGGATGTTAAGAATTCGACACGGCAAATGGGTACACTTTACTGCAATTCCGCTACTAGTAACAATACAGGAAGTTCATCTATGATATTAGATGATTCAATGTCTAGCAAAAATTATTCAGATTACAACCAAAACCAGCAGCAGCCAATGGAAACAAACCTGGAAAATCAATGGTTCAATAACTACCAGGCGACAACAGAAGCAGGTGTTGTTCCTTCATCAAATCAATCAAATTCGAATGTACATTTACATATGTCTGCTGCTGAATGCAATTCTGCAACAGACGCAAACGAAGTTggtaaatatttggatttggacGAATGTAAGAGGGAAAGAAATGTCGAGTCTGTGGCAGAGCCTACTGATGGATGTGGGAAGACCGTTGAACCGCCTCCTCCGCCCCCATCTTCATCGACATCCTGTTCATTTACTGAAAATAGCATGGCGGGCATTTGCTCAACTGCCGGCACTTTAAATATACGTACTGATGAAAAAATGCCTGCTAAAGGCGAGATTTCTGAACAGGAAAGCAATTGTGACATAGATAATTCCTGGAGTCAACcgATTTACGGAGACATTTCCGCCCGATTCTTTAAAACCACTTTTCCCGGGATATTTCAACAGGATAATGGCTGGAACCACGAAGAATATTTTGCTGTTCAGGATTTAAGTGCTTCAACGACGTCTCAAACAGATAGGACGAAAAGTTTCGATTTTCGCCTTCCACCGGATGATGGTACAGTCGTAGCAGACAACAGTGCGAGCAGCGGATTGACAATGTTCTCTCAAAATTCCaatgataattgcaatattGATGTAATGCCCTCTACGTCGGCCAAAGTTAGAAAACGGCGAAAACGAAGCTCTCAAGATGGCAAAGCGTCTGCATCTGGTATAAGGCGAGTGCAACCGACGTCAACTATTACTTCGCAGCAGCTAATGGAAGGACAAGGGGAAATGCAGGCCATTGACTATAATTTCCAACAGGAACATTTACCCAGTACATCGTCAGCGCTCTTGGCTGGTCCACCGAACGCCGAAGCAATCGAAATAACCCCTTCTTCATCTAGTGGATCACAACAACAGAGAATACGTACTAAAATTTATGAGTGTAGCCACTGCAATGCCAAATATTCGAAACTCAAAGATCGTAATGCTCATTTAGTGGATTCCCACAATTATGTTCGTCAAAATAGACGTCTTGTGTGTCTCACAAATGGAATGGCTGTGTCTATGTCAGATCATGCTGCCACCGCTACGACTAGTAGAGGGGCCAATGTATTATTGGCATCCTCAGATTTAAATGCAGATGGGGATTTCAAGCAGGGCATCGTTAAGATAGAAAATGAAAATGCCCACCGTGATGTGTCTGGTTTTGAACATATCAGTGCCGATTTGAACGCAAAAACCGAATTTGTTGAGGACGACAAAAACAATTTGTCTCTGGTACCATTAACAGCTTCTTCTTCAGCCTCCGATCAGTTGGGCGTAGATACAAAAcaagcttcaaattttaaaccctTGTCCGTTACCACAGCCTCGAACAAATTGACGACACTCTATCGGATGTTGGTTACATACAACATGACCACGCTAAAGCAAAGTCAAAGATTATCTGAGTTTGATGAAACTCTGATTAAATCCTCCATATTCTTTTGTTATGTTTGTCGTGAAAATTTTAATTCTGTGAAGTTGTACGATGCTCATTTAACTGAACATCCAGCTGAGTGCTTTACGTGtgggaaaaaattccaaaggtgGAAGAACTTCTCATTGCATTTAAAACGTCATCTTGGATGGAAAGAATTTGGTTGCacggtttgtgataaaaagttTGTGGTGCGCAGCGCCTTAGTCGAACATATGCGAATGCACTCCGGTCTATCGccattaaaatgcaaaatatgtgGTAAGCACTTCAAACGCTACTCTAATCTTACCCAGCATCGTAAACGTCACACTAAACAAGTAGTGCGTCGAAAGGAATACGTGTGCTATTGCGGCGAAGTATTGCCCTCAAAAGCACGATTTTTGTGGCACAAGGAAACACATGACTCTAAACCTAAATGTTGTCCTCATTGCTGTGACCGTTTCGTACATGTGAATTCGCTCCGGCGTCATATACGTCTCGCTCATTCGGATAAATTCGATTATACTGAACCTATGGAGTGTCCTATCTGTAAACAAATTTTCGCCAAGGCATCTATGAAGGCTCATATGGCTACCCACTCCACTGAGACCCAATATGACTGTGCGATTTGTAATAAATCATTTTCAACCAAATGGAACCTAAAGATTCATTCTTGGGTACATGCCAATCGTACCGCCAAACCGTTTAAATGTGAACACTGCCCCAAAGCGTTTGTACGCGAGGTTGACTTCAAGAACCATATGAACTCACATAAACAAATCAAGCCATACACGTGCGAAGTTTGCGGGTGCAAGTTTATCCGCAAATACAATTATATGCGTCACAGACGAGAACAtcatggcaataaaaaatacacctGTGATCTGTGCAAGAAATCTTTTCATCGTCACTACTACCTGATAGAGCACAGGCGAATTCATACTGGAGAAAGGCCGTTCCAATGTACGATTTGTGGCAAAAGTTCGACAACAAAAACCAATCACAATAAACATCTTAAAATACATCATTCACGGGATCCGTTTACGGTAGAAGTCTAA
Protein Sequence: MGENVQCPVCTLYLHAGMNLSDHLETHPKEQVIRALVQMTISGGSGGGTAALASVLKGTCSNSAENNKSPSEQEEKSISSNDKIIESNIASTSNSCNASISSSASNCSLSNQSNTTSQNSNNVLNFSNTSIADNSRSESQTPCKSALKLEEAPVASKDQSGKEATSEVYVHSHRPYTSSSNDVPANTDPNFGIFGNPRFQNQHRTVGSQQHQQMPPPPAPQGQHGEIPRTILPPPPPMPQSMSSQSIQTVFQSIQAQQLSNSQQQHHSSHARQPHIYTSQHHQHPPQHQQDMKVIYASGLPPPPPLQLFSSYQQPSQLQHHHQKPPPAYGTAISQIRSQNKHQLNGQFAGQHHHTSITSNADAILHQQHHLHQQQATHPHHIRMHGNVAHQLHPIATKHLFSKTNDIPQTTSSTLSSQTTSRQSSNVHQQHQHGKYILPSLQQQPISVENSALYNNCPTANDSQEKTIKASTANGSGSAAHISHSAQPNVGINPAVASASMAVVTASTLNRPTNSPFAALLAAASPSAASSVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDNGEFSVIERIYQSPPSVLHIHDDADDDEEDDDKTGSSANGNNTPTCTNEVIVKDSKEEAKDANIKHPKKKISSQSTKNDNNSQTANTNKMSIDSKAQSRKLKHFESSTSSDNEVEDFVSISSDSDEEEFISHERNGQTNKNTTEKIKKNQSDQTLPPTPSTSASAPRLQHPSPTNLETHSATAVSTSNASNSTSTVHQNSNTTRKKSSKNTITVLSDVQLNLNEYLDLVGNIIASSKVAAQRRTLTAIAPIPLVKIEKEEPMDDYATTPADTAEQHTLPPTPLKANKQETEELTDNPSCSSTNNKSSKISLTDQTVLEKDEKKPQILENNSDSSKIISSLIPNSSQVTSVIRMATTSLQQSQQQQQQQNSQQSIVRSNENTSDSNESKTEAEDLSQHQRNLPITGQNKTTSLGLPTLGRKGPKKLVIKPKSSKTSSNDFHFDDQQPSTSAKALEEYNKLSLRTQEKSVNEPEVQVKNEPLTSIAFESNQYTQPTGYSSILEQQLTSKEPIMLCKEEKPCIQETNVPTDVKDMKVENNVNEDARVLYDFATSKKGQASSKPSTFPSPSSLFSKNQTVNQKDKENVSESKVCNLHSTNEAQLVHSSHLEATSKNGEVQNKASTASSSDNNDCSEIFPDFPFNYLNNNNNSHISTNDQTVDVKNSTRQMGTLYCNSATSNNTGSSSMILDDSMSSKNYSDYNQNQQQPMETNLENQWFNNYQATTEAGVVPSSNQSNSNVHLHMSAAECNSATDANEVGKYLDLDECKRERNVESVAEPTDGCGKTVEPPPPPPSSSTSCSFTENSMAGICSTAGTLNIRTDEKMPAKGEISEQESNCDIDNSWSQPIYGDISARFFKTTFPGIFQQDNGWNHEEYFAVQDLSASTTSQTDRTKSFDFRLPPDDGTVVADNSASSGLTMFSQNSNDNCNIDVMPSTSAKVRKRRKRSSQDGKASASGIRRVQPTSTITSQQLMEGQGEMQAIDYNFQQEHLPSTSSALLAGPPNAEAIEITPSSSSGSQQQRIRTKIYECSHCNAKYSKLKDRNAHLVDSHNYVRQNRRLVCLTNGMAVSMSDHAATATTSRGANVLLASSDLNADGDFKQGIVKIENENAHRDVSGFEHISADLNAKTEFVEDDKNNLSLVPLTASSSASDQLGVDTKQASNFKPLSVTTASNKLTTLYRMLVTYNMTTLKQSQRLSEFDETLIKSSIFFCYVCRENFNSVKLYDAHLTEHPAECFTCGKKFQRWKNFSLHLKRHLGWKEFGCTVCDKKFVVRSALVEHMRMHSGLSPLKCKICGKHFKRYSNLTQHRKRHTKQVVRRKEYVCYCGEVLPSKARFLWHKETHDSKPKCCPHCCDRFVHVNSLRRHIRLAHSDKFDYTEPMECPICKQIFAKASMKAHMATHSTETQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEHCPKAFVREVDFKNHMNSHKQIKPYTCEVCGCKFIRKYNYMRHRREHHGNKKYTCDLCKKSFHRHYYLIEHRRIHTGERPFQCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -