Basic Information

Insect: Musca domestica
Gene Symbol: grau
Assembly: GCA_000371365.1
Location: Scaffold20091:76455-82433[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.023 1.1 9.5 3.8 2 23 248 270 247 270 0.95

2 10 0.17 8.4 6.8 0.1 6 23 279 296 279 296 0.96

3 10 4.1e-06 0.00021 21.3 2.3 1 23 302 324 302 324 0.98

4 10 5.3e-06 0.00026 20.9 4.1 1 23 329 351 329 351 0.97

5 10 3e-05 0.0015 18.6 0.7 1 23 359 382 359 382 0.97

6 10 0.00089 0.044 13.9 0.4 2 23 389 410 388 410 0.97

7 10 0.017 0.83 9.9 0.0 2 23 426 448 425 448 0.92

8 10 0.0017 0.082 13.1 3.2 1 21 456 476 456 479 0.96

9 10 1.7e-08 8.4e-07 28.8 1.6 1 23 485 507 485 507 0.99

10 10 5.8e-06 0.00029 20.8 1.7 1 23 513 536 513 536 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.023	1.1	9.5	3.8	2	23	248	270	247	270	0.95
2	10	0.17	8.4	6.8	0.1	6	23	279	296	279	296	0.96
3	10	4.1e-06	0.00021	21.3	2.3	1	23	302	324	302	324	0.98
4	10	5.3e-06	0.00026	20.9	4.1	1	23	329	351	329	351	0.97
5	10	3e-05	0.0015	18.6	0.7	1	23	359	382	359	382	0.97
6	10	0.00089	0.044	13.9	0.4	2	23	389	410	388	410	0.97
7	10	0.017	0.83	9.9	0.0	2	23	426	448	425	448	0.92
8	10	0.0017	0.082	13.1	3.2	1	21	456	476	456	479	0.96
9	10	1.7e-08	8.4e-07	28.8	1.6	1	23	485	507	485	507	0.99
10	10	5.8e-06	0.00029	20.8	1.7	1	23	513	536	513	536	0.97

Sequence Information

Coding Sequence: ATGGTGGAATGTTTACTCTGTTTGAAAACCACAAAAGATGCAGTTGAGTCTGACTGCATACTGGTCGATTCGGCCCAATGGGAAGACCTAGCTATTAAAAAGTTAATCGATAAACATCTATGGCCTATTGACACCATTACTCCTCAATCATGCCTTTGTCCAACTTGCTGGCAAGAATTAAAtggatttcataatttttatactcgCATCGAGGAGGCCCACAATGATTATAAATCGCTTTTAAAAGCGGAAATCGATCCATTGGAAGAAGAGAGTAAGCCAAAAGACTTGCTCTTGGAAAATCTGCTCGAACCGGAAATAGTAATTGGACAAACACTGGATGTTGCCATAgttataaaacaagaaaatgaGGAAACGgcaattattccaaaaattgatAGTGACAATGAAAAAGATCCCAAATCACAAACCCAATCAGATGATGATAGAGAATTCATGGATGATTATAGTGGTAACAGTGATGAGAGTGAAGAAAGTGACAGCGATGACGACTTGCCACTGATACATAGAACaaaaaaaTCTCCAGCGAAAGCTAAATCTGAAGTAAGCCTTGAATCCGATGATGGCAGTGTTGATCCCGATCCATTGCAGCCACGTCGACGAGGACGCAAAAAATCATCGTCTGAGGTGAAATCAAATTCAGCGACTAGGAAATCGTACTATCAGCCCAAAACCAATCGCTTAGAACATGAtaaatttttgcaacaacactaTAAAATAACATGCAACAAATGCCATTTGCCCTTCGACACATTCCCTCTGCTCTGTAAACATTACAGTAAAGAGCACAATGAACGCGGCTTTGTAACATGTTGTGAAATGAAATTCTATGATCGTAGTTTACTAGTGGATCAcattaatttccatttaaatcCCGAGTATTTTAAGTGCAAAGAATGTGGTAAGGTTTTAACACAAAGACGTTGTTTGTGGGCCCACATGAAACTGCACGAAGAGAAGAAATTTTGTTGTGATGTTTGCGATaagaaatttgtacaaaaatctaAATTGGAGAGACATAAACTGACACATTTGCCGCAGCAGGAGAAAAAGTATCCTTGCAGTGAGTGTGGTAAATTCTTTGGCAATGAATATGTTTTGACACAACATCATAGGGTGGTCCACTTAAACATCTACGCCAAGGTGTGTGAGGTTTGTGGTCAAACTATGCCCGATTCGAATTCTTTTAAGCGGCACATGGAAAAGCATGAGAACATAAGTGAAACTAAAACAGCAACACCCACGGCAACGGTTAAGTGTGATGATTGTGGTCTAATATTGGCTGGACCACTTAATTTAAAACGCCACAGAGATTTACAGCATCCGCCAGGTGGCAAACGGGATTACACCTGTCATATATGCTCGAAAGTATCACCTAATATGAGAGCTTTGAAAAAACACATACGCTGTACACACGAAATGGGCTACGATTTCAAGTGTACAATGTGTGAGAAGGCATTTAAACGATCGGATAATTTAAAGGCGCACATGAGTACCCATACTGGCACACCGCTCTATTCCTGTCCGTGGTGTCCGAAAACATTCAACTCAAATGGCAATATGCATAATCATCGAAAAAAGGCTCATCCCGCTGAATGGGAAGAGGCGCGTCGTAAAAAGTATTCTGGCAATTTGCCGCCTAATTTTAAGCCGCCAACTACAACTACGACGAACAACAATTCCTCCCATTACTTTCCAGTAACAGTAAACATGAATGGCAActag
Protein Sequence: MVECLLCLKTTKDAVESDCILVDSAQWEDLAIKKLIDKHLWPIDTITPQSCLCPTCWQELNGFHNFYTRIEEAHNDYKSLLKAEIDPLEEESKPKDLLLENLLEPEIVIGQTLDVAIVIKQENEETAIIPKIDSDNEKDPKSQTQSDDDREFMDDYSGNSDESEESDSDDDLPLIHRTKKSPAKAKSEVSLESDDGSVDPDPLQPRRRGRKKSSSEVKSNSATRKSYYQPKTNRLEHDKFLQQHYKITCNKCHLPFDTFPLLCKHYSKEHNERGFVTCCEMKFYDRSLLVDHINFHLNPEYFKCKECGKVLTQRRCLWAHMKLHEEKKFCCDVCDKKFVQKSKLERHKLTHLPQQEKKYPCSECGKFFGNEYVLTQHHRVVHLNIYAKVCEVCGQTMPDSNSFKRHMEKHENISETKTATPTATVKCDDCGLILAGPLNLKRHRDLQHPPGGKRDYTCHICSKVSPNMRALKKHIRCTHEMGYDFKCTMCEKAFKRSDNLKAHMSTHTGTPLYSCPWCPKTFNSNGNMHNHRKKAHPAEWEEARRKKYSGNLPPNFKPPTTTTTNNNSSHYFPVTVNMNGN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00679777;
90% Identity: -
80% Identity: -