Basic Information

Gene Symbol
-
Assembly
GCA_000371365.1
Location
Scaffold18614:1277547-1281415[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 6.3e-06 0.00031 20.7 0.5 1 23 115 137 115 137 0.98
2 11 8.6e-05 0.0043 17.1 0.3 1 23 143 166 143 166 0.96
3 11 1.2e-05 0.00059 19.8 0.6 1 23 172 194 172 194 0.97
4 11 6.6e-06 0.00033 20.6 0.8 1 23 200 222 200 223 0.95
5 11 7.8e-07 3.9e-05 23.6 0.2 1 23 230 252 230 252 0.98
6 11 0.016 0.79 10.0 1.9 2 23 259 281 258 281 0.94
7 11 0.55 27 5.2 0.1 3 23 287 306 286 306 0.76
8 11 2e-06 9.9e-05 22.3 1.5 1 23 312 334 312 334 0.98
9 11 0.0062 0.31 11.3 5.2 1 23 340 362 340 362 0.99
10 11 0.02 0.98 9.7 0.7 2 23 369 394 368 394 0.84
11 11 0.2 10 6.5 0.1 1 21 400 420 400 421 0.96

Sequence Information

Coding Sequence
ATGGTACGTAGCCGCCGATCCTTTTCAAAGGAGGATGCCTCGTCTGTGCTAGCAGACAGTGGTATATCGCTATCGTCGCCGCCGGCGAATCAGAAACACTTTTCGCATCTCAACGAAGACGAAGAGGAAGCCATTTTGGAAGAGCTATGCATAACGGATGACGAAGGAGATTCCGATGTAATTCAAGTAGATCAAATCGGGAAAGCGGCAATTAGCGACAACGAAGAAAGCAGCTCGTGCTCTAAGTCCGACTTTGAGCAATTTAGACGAACGTTGCCGGAAAAACAGATACATCATTCAGACGTATCGGACGTGACTCCGTCCAAACGTGCGCGAAAAAGTTATGTGTGCGACGTCTGCCAAAAGGAGTTCCGTGGTAAATCGGATCTTAGTAGGCACAAGTTAATCCACACCGCAGAAAGGCCTTACGAATGCAGAATTTGTGGCAATAAGTACAGGCAGGAGATTAACCTGAAAAATCACATAACATCGGCACACAATAAGCAGAAAGAGTTTGCCTGCAAAGAATGTCCaaaaaaaTTCGCATTGAAAGAAAGACTTCGTTTGCATATGCGAATTCATACGGGCGAAAAACCCTACGCGTGCTCGTTATGTGACAAACGATTCGCTAgggggggACAGCTGAATCAGCACATGATTAGTCATCACCAGGACGCACCGAAACAATATAGATGTGAAAAATGTTCGGCACCCTTTTCAACTCAGGCAAATTTAAAAGCTCACATGCAGGGTCATGATGAGACGCCTGATTGTTTCTGTGAAATATGCAGAGAGCATTTCGCCAACGACGTCCTGTTGAGGGCTCACATCTACAGAATGCACTACAAGTTAATGGACTGTGACATTTGTAAAAATCCCATCGAGGAGGAGGATTTGGAAGCTCACATGAAAACTCACGCAAATGTTAAAGCATTTGTTTGTGAAAACTGCAACTCGATGTTTTCACAGAAATCGCAATATAATGTACATATGCGTATGCATACCGGAGAGAGGCCATTCCAATGCAGGatTTGCTGCCAGACTTTTGCCCATTCCAGCGTTTTGAAACTACATATACGCAAGCATACGGGGGAAAAGCCATTCAATTGTCTGCTGTGCAAAGATGATGAAGTGGCTTTTTCGCAGCTTGCTCACCTGAAGACTCACATGCAAAAAATACACAAGCAGTCAAAACCTTATATGTGTGAGGGTTGCCGtgacttttttaaaatcaaactgGATTTGGAAGCGCATCAGCGTGACTGTAAAAAATACACCAGTAGAGATGAAGAACAAAGCACTAAAGGAGACGAGACCAATACCTTGTCACACATCCGTTTTCTAATGGCCATTTTGTTGAAGAAAATATCTTCAGAACGAAAATTACAACAGTTAGGTTTTGAAAAACGTCTTATCGATAACGTTTTAATAGCCGCACTGAAATTAGCCAACCGAAAAGCTTTTGAAGATTTGAAGTTGACGCAACTGGAAAGAATGCGTCTGAATGTCGACGAATTTCTCAACTGGATTGTGCCCTCAAAGGTTATGCAAAAGTTGAAGGAAGATAACCGAACAGTGGATGACATTTTGGAGAATATTGTTTCTAAGTACATGAAACAGAAATGa
Protein Sequence
MVRSRRSFSKEDASSVLADSGISLSSPPANQKHFSHLNEDEEEAILEELCITDDEGDSDVIQVDQIGKAAISDNEESSSCSKSDFEQFRRTLPEKQIHHSDVSDVTPSKRARKSYVCDVCQKEFRGKSDLSRHKLIHTAERPYECRICGNKYRQEINLKNHITSAHNKQKEFACKECPKKFALKERLRLHMRIHTGEKPYACSLCDKRFARGGQLNQHMISHHQDAPKQYRCEKCSAPFSTQANLKAHMQGHDETPDCFCEICREHFANDVLLRAHIYRMHYKLMDCDICKNPIEEEDLEAHMKTHANVKAFVCENCNSMFSQKSQYNVHMRMHTGERPFQCRICCQTFAHSSVLKLHIRKHTGEKPFNCLLCKDDEVAFSQLAHLKTHMQKIHKQSKPYMCEGCRDFFKIKLDLEAHQRDCKKYTSRDEEQSTKGDETNTLSHIRFLMAILLKKISSERKLQQLGFEKRLIDNVLIAALKLANRKAFEDLKLTQLERMRLNVDEFLNWIVPSKVMQKLKEDNRTVDDILENIVSKYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-