Mdom005483.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Musca domestica
Gene Symbol
-
Assembly
GCA_000371365.1
Location
Scaffold19377:82345-86314[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00014 0.007 16.4 4.1 1 23 295 317 295 317 0.99
2 11 1e-05 0.0005 20.1 2.7 1 23 323 345 323 345 0.99
3 11 1.2e-06 5.9e-05 23.0 1.3 1 23 351 374 351 374 0.97
4 11 0.0051 0.25 11.6 4.7 1 21 380 400 380 402 0.95
5 11 3.4e-05 0.0017 18.4 2.9 1 23 408 430 408 430 0.99
6 11 6.6e-05 0.0033 17.5 2.1 1 23 436 458 436 458 0.98
7 11 0.00023 0.011 15.8 2.1 1 23 466 489 466 489 0.98
8 11 0.00028 0.014 15.5 0.9 1 23 495 517 495 517 0.98
9 11 0.00057 0.028 14.5 0.3 1 23 523 545 523 545 0.98
10 11 7.1e-06 0.00035 20.5 1.2 1 23 551 574 551 574 0.96
11 11 1e-06 5e-05 23.2 1.9 1 23 588 610 588 610 0.98

Sequence Information

Coding Sequence
ATGTATCCAACTACGACATCTGGGGCAAAACAATTGCTGAGCATGGCCGACGATAATTCGGATCTGGAATCATATTTGGATGAACTGGAGAAACATGTAGAAGAGGATATCACAGCGATTTATTCGGAGGTTGCCAACGAAGAAGAGGAAAAACAACAAGaGGAAGATGATGTTGAAGATGACGACGCTTTGGATGATGCCGAACTAGAAGATGGTACCATATTTATGGATGAGGAAGGAAATTATTACTATCaaagcggtaaaaaagcagttcaagtaaaacctgtaaaaaaggaaaaatccattgtaaaatcagtggctgctgcagtaaagaaaagaaaactatCTCAATCTCCACAACGTCCtgtgaaaaaggaaaaactcaaCACTAGTAAGGAAAGTCCTAAACCACCTAGTCCGACAAAATCCACAAAAACTAATTCTAGAAATAAAAATGCAGGCaataattcaatattaaaatatcttgATATacaaaagaaacccaaagaaacaaaagctgaaacacccgcaagtcctgaaaaaacaaaaaccacagCCAGAAAGCAAACGGCTGTTAAAAAGGCGACCATTTCTCCAAGGGCTACAACAGTTCGTACCAGGGGACGAAAAGCCACAGAGCTCAATGTGACAACAAAAACTGAGCCGGCCGATACAACTGATGCCAATATAACAGCAACGACGGTAGATCAAACCATAGCCTCTGAAGTCTCCGAAGCTAATGGTGAGGTCTACGATTTCGATGAAACTGAAAGAACTGTGAATGGGGCAGATTTTACCGTGGACGAGAGCAAAGAAGAAGGTGTCATCGAGAGCGAAGTATTGCTTAAACCACTTCATATTACTCCAGATTCTGAGGGCCAATTTAAGTGTCAGATCTGTGACTACAGCACAAATAAGAAATTTCTTTTGACGCGTCACTTTAGGACACATTCCGATGACAGACCCTATAAATGTTCTGTTTGCGAGAGGGGTTTCAAAACTCACAATTCTCTGATGAACCACATAAATACCCATTTGGGCAACAAACCCTATAAATGTGGCGATTGTGAAATGAGCTTTACCACATCGGGTGAATTGACAAGGCACAGACGTTACCGTCACACCCTCGTAAAACCCCACAAATGTACTGAATGTGATTATAGTAGTGTGGAGTTAAGTAAACTTCGTCGCCATATGCGTTGTCATACGGGAGAAAGGCCCTACCAATGTCCTCATTGCACCTATGCTTCGCCAGATACCTTTAAATTGAAACGTCATATGCGCACCCATACCGGTGAAAAGCCATATGAATGCGATATTTGCCATGCCAGATTTACACAATCGAATTCACTGAAATATCATCGTCTTATACACTCGGTCAATGATAAGCCGGTATTCCAATGTAACTTGTGTCCCACAACGTGTGGACGTAAAACAGATTTACGTTTGCACATCCAGAAATTGCATAATTCCGAGACACCATTTCCCTGCAAACGTTGTGGCAAAGAACTGCCCGATCGTTATCAGTATAAAATGCATGTTAAAACGCACGAAGGAGAGAAATGTTATCGCTGCACATATTGCCCATATGCCTCCATATCACAACGTCTACTGGACACTCACATGCTAATACACACAGATACCAAACCCTTTGTATGCGACCTCTGTCAACAGTCCTTCCGCCAAAAACAATTACTTGCACGTCACATGAAATTGTATCATACGGCAAATTATGAGCCACCAAAACCCCTGAAAAAGGGTCACGTGTGTCCACACTGTGAGCGGGCATTTGCCTTTAAAGGCAATCTAATGCGCCACATGGAAACTCATGATccaaattctaaaataaatgaggagaaacttaaaataaaaatgggtCGTTTAAAACGGGTACAACCAGATGGTACAGTGGTCACACAAATAAAAAGTTCCTTTATTTACAACGAAGATGAGGTGGTGAATGCCACTAATGAACGTGAAATGTCTGCCGATAATCAAGAAAATGTTATCTTTGAAGATGAAAATGGCGAACCTGTACAATACGTGTACGAGGATTATGAGCCTGAAGAGGAAGAACCAGAGGAAGAGGAGGAATACGATGAAAATTATCAGGAATTGGAATACTACGAAGAGGAGGATGAAAAACCACAGTTtgtaataaaaacagaaaaatgtaatCGAGAATTTACGACAATTGATTTGCCCGCTGAATTAAATgtaaagaaagagaaagaatctgTGGTTGCAACAGAAGATGATGAATATATGATCATTGAAGTGATGCAAGATGCAGAAGAAGTCGACTTGGAGGGACAACAAGAGTTTTGCCAAAATTCACCAGAAAAACAACCAAAGATTACCAAACCAGCACCTTCTGTTATAAgCAAATCAAAAACTTCGGCTTTAAAGGCTATTACCGAGGATTGTTTTGGCTTTGATGATGACGTTGAGTCTGATGATGAGGTAGCCGAAAATACTGAACATACTGAAACATCGGAGTTGATAGAAATCCTCAAGGAATAA
Protein Sequence
MYPTTTSGAKQLLSMADDNSDLESYLDELEKHVEEDITAIYSEVANEEEEKQQEEDDVEDDDALDDAELEDGTIFMDEEGNYYYQSGKKAVQVKPVKKEKSIVKSVAAAVKKRKLSQSPQRPVKKEKLNTSKESPKPPSPTKSTKTNSRNKNAGNNSILKYLDIQKKPKETKAETPASPEKTKTTARKQTAVKKATISPRATTVRTRGRKATELNVTTKTEPADTTDANITATTVDQTIASEVSEANGEVYDFDETERTVNGADFTVDESKEEGVIESEVLLKPLHITPDSEGQFKCQICDYSTNKKFLLTRHFRTHSDDRPYKCSVCERGFKTHNSLMNHINTHLGNKPYKCGDCEMSFTTSGELTRHRRYRHTLVKPHKCTECDYSSVELSKLRRHMRCHTGERPYQCPHCTYASPDTFKLKRHMRTHTGEKPYECDICHARFTQSNSLKYHRLIHSVNDKPVFQCNLCPTTCGRKTDLRLHIQKLHNSETPFPCKRCGKELPDRYQYKMHVKTHEGEKCYRCTYCPYASISQRLLDTHMLIHTDTKPFVCDLCQQSFRQKQLLARHMKLYHTANYEPPKPLKKGHVCPHCERAFAFKGNLMRHMETHDPNSKINEEKLKIKMGRLKRVQPDGTVVTQIKSSFIYNEDEVVNATNEREMSADNQENVIFEDENGEPVQYVYEDYEPEEEEPEEEEEYDENYQELEYYEEEDEKPQFVIKTEKCNREFTTIDLPAELNVKKEKESVVATEDDEYMIIEVMQDAEEVDLEGQQEFCQNSPEKQPKITKPAPSVISKSKTSALKAITEDCFGFDDDVESDDEVAENTEHTETSELIEILKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-