Mdom004981.1
Basic Information
- Insect
- Musca domestica
- Gene Symbol
- hang
- Assembly
- GCA_000371365.1
- Location
- Scaffold19520:103100-135013[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.12 6.1 7.2 0.9 3 23 237 258 236 258 0.92 2 19 0.35 17 5.8 3.8 3 22 362 381 360 381 0.90 3 19 0.015 0.75 10.1 1.0 1 22 456 477 456 479 0.90 4 19 5.5 2.7e+02 2.0 0.1 2 21 491 510 490 511 0.91 5 19 0.0012 0.059 13.5 0.2 3 23 604 625 603 625 0.96 6 19 3.2e-05 0.0016 18.5 0.1 1 23 633 656 633 656 0.96 7 19 5.2e-05 0.0026 17.8 0.0 2 23 746 767 746 767 0.98 8 19 0.001 0.049 13.8 2.7 2 23 818 840 817 840 0.95 9 19 0.0041 0.2 11.9 0.2 2 23 849 871 848 871 0.95 10 19 0.0028 0.14 12.4 0.1 1 23 884 907 884 907 0.95 11 19 0.00013 0.0062 16.6 1.1 1 23 974 996 974 996 0.99 12 19 0.0019 0.096 12.9 0.9 1 23 1004 1027 1004 1027 0.96 13 19 0.15 7.3 7.0 0.4 2 20 1035 1053 1034 1053 0.94 14 19 6.2e-05 0.0031 17.6 0.1 3 23 1125 1145 1124 1145 0.98 15 19 0.00055 0.027 14.6 1.1 1 23 1180 1202 1180 1202 0.97 16 19 0.00037 0.018 15.1 0.9 2 23 1280 1302 1279 1302 0.91 17 19 1.4 68 3.9 0.1 3 19 1323 1339 1322 1341 0.92 18 19 0.1 5.2 7.4 0.9 3 23 1357 1377 1357 1377 0.97 19 19 0.0023 0.11 12.6 0.7 1 23 1638 1660 1638 1660 0.98
Sequence Information
- Coding Sequence
- ATGTCGGATGAACGTCTGCAGCAGCAGAACCAACAGAGGAGACACAACTGCTGCCGCCTGTGTTTAGCTCCAGACAACGAATGTATATCGATTTTAAACAGTTATGCAGCCGACAAGGAGCCCTTGGCTAGCAAAATCCATAGCTGTGTATCCATCAAGATATCATCAACGGATAATCTATCGTTACGCATCTGTCATGCCTGCATCAGTTACTTAAATTCCTGGCAATCATTCAAAAATCGTTGTTTATCAGCACAAAATAAACAACGTTCCTGGCTAGATGGATCATCGTCAccgcaaaaaacaaaatccaacgctgaacaacaatcacaacacacaacaacagcaatatcagATAATCACAGCGAAGATCAGCAGCAAAAAGATGAACAATCACTGGCCTCCTCCATATTGGAGGGAATATCAACGTTGAAAAAACGCAAATCATTAACAGTCTATCCTCTACCTGCGGTACAAATCAAGGATGAACCAATGGATGCAGAAGATGATTACAATAATGCAAAACATAACGATGAATCCGATGAGATGGTTGATCCAACCATGTTTTTAGAGCGTACAGCCGACGAAGGTGAAGAACCCATTATGGATTCTTCATCGGCCTATGATTATGATAATATAAGACCACCTGTTGATATTGCACCTTTACCAGCTGGCACTGTTATTCGCATGAGTACCAAAGAAGCCGCCTGTCGTGCTTGCAATTTGAAATTCTCCACCCGGGCTAATGCCAGGAGGCATGAGAAGAATTTACATCCACATTTGTTTGATACACTGGAAGAGAATGACACTACACTGAATAAGCAAACGGCAGCATTAAATGCCTCATTGGAACTGCAAAGGGCCGTGGCTGCGGCTGTCGCGGCTGATGCATGTAAATTGACAAGTAGTGGTGTTATAACACAACAAAAATACCGCCACGAGGTGGTTACCGCTTTCAATAATTCCTGCGAGGTTGGCTATGATTATGACAATCCAGAAAAATATCAGCATTTGTTGACAGATGAAAAGATTGTTTTTCTGCAACAAAATGATGAATTTATACGCCAATATCATGCAATGACTTGTCGTTGCTGCAATCGTTTCTACACCACCTACAAAAACTTTATGGCTCACATGCGTAAAAAGTACCTTACATTGCCACGGAACTGTTGCTTCAACTGCCTGAAATTGAACGATTCCAAGGCATTGTTTATATCGCATTTAAAGAAACGCAATTGCATAAATCTGCACAGGGTACTACACAGCCTCATGTcgaaaaatgccaattttgcAGCGGCCGTTAGTGCCACAGTTGCAGCGGCCCCGGAAAAATTGCGAGCCAAAGAATTGCTGGTGAACAAAATGTACGAGTGCCGTTTGTGCCCGAAAACATTCCGTTTGAAGTTGGAATTTCGTACTCATGTCTATGATGAACATGCCGATGCCCAGCGTAAAGATATCAACACCACACAGTGTAGTTTTTGTGGCATTGATATTGAAGATCCGGCCGAACGTAAACGTCATTATAATAATATGGATTGTATTGTTACGTTACGCTGCGTTACATGCGATACTAAACATGAAACGCAACAGAAATTCATGGAACATGTTCAGGATAAGCATATGACAAACTTTGGCGAATCAACACCATTTGGTTTGGGCAATGCGGACAACTCACCGGGGAAATCATCGAATGTGGGAGGAGTTGGTGGTGCCTCATCCACCGATGAATCCCGCAACAGTTTTAATGTAAATCTTGTAAATACAAGCCAACCGAGAGCTCAATATTTTTCACGTATGCCCCAGGCATGTCCGATATGTGGTCAACAATACAATAACTATAACAATGTACTACGGCACATGGAATCCAAACATCCTGATCAATTGCCACAAACATATAAGTGTGTTAAATGTGGTCAAGGTTATCCAAGATTATCGAATCTTCGTGAACATATGGTTAGTGCTCATGGTGCGGACAAGGCACGTCACACAGGATTTGAGTATATTGTCAATGCGGATGCTGTCAAAGCTGCAACCGATGGCGGATCATCGACGGGAGGCAATTCCCATAGCCAATATACCGGACGTTATGATTATGTTATGAAGGATTTGATGTCTATAACAAATGGTGGGACACTGGCTGATGACGATggcgaatttgaaaattcctcAAAGAAAATGCGTTTCGATGGCCCCGGCTCAAATGGCGGAACACCAACCAATGCCAGTCCCCGTGAATGTCCCATTTGCAATGCGGTATTTGCCAACAACATTGGTCTCTCGAATCATATGCGTTCGCATCAGAGTGCAGCCAATAATAGCTTCAGCTCAAACTCCAAATCATTGGGCGGTGGTAATAGTTTAATGCACACAACGTTGTCATCAGGAGGAACCCAGgccattttaaagaaatccctGGAACAGGCTGCCGATCGTCGGTTCCGTAGAATGCGTTGTCGCATTTGTCAGCGTCGTTTCTCCTCGAAGAAATCCTATCGTTATCATATGTTAAATGATCATCAGATACGTAATGTTCAGTTTATCAAGTGTAAGCTGTGCGATGCTGAATTTGCCTATGAAAAGGGTCTCAAGGTGCACATGTTTAAGATCCACAATACTTTGTTGAAAGACGACATGATTATCAAACAATATGAATGTGAAATATGCTCAATTGTATATCGTACCGATGTTGAGTTGCAACATCATTTGGCCAATGTTCACAAGAAACAGGGTGGTGCGGAACGTACAATGTCAAATGATGGTGATGATTATAACATGGATGAATCGGTtggtggaactggtggtggtggtggtgcagaTGCTACGGCCGCAGATTTGTCGGGTATATCTACACCTGTTAGTGTTTCAGGAGGAGCGGGCGGCAGCGGAGGTGATGGCAGTTCTGGTCCCCTGTACTGGTATCAGTGTAAATATTGCCCCTCCAATTTCAACACTAATAAGAAATTGGCCATACATATTAATTCCCACGATGAATTCGATTCCAATGACTATTCCTGCAAGGATTGTGGCAATGTATATAGCGGACGCAAAAGTCTTTGGGTACATCGTTACAAGAAACATCCCCAAATTCCCGAACCATCCGAATGTGTTTTGTGTAAAAAAGTATTCTTCGACAGTCAAATGTTGGATCATCACATACCGACATGTAATCGCAAGCCCATTACTTCGGCCAACAATGAAACAGGTGGCGCTGGAACACAATCTTCTGCTGCTGCCATATACAAACACAAAACTGGCGACGATGACGAAGACGATGATGACCATTCCCGTGATGCTCACGACACTGATGCGATTTCCACAAATTTACAAGCCACCGCTGGCAGTATGAAAATCAAACTACCAGAGGTTGCATGTACAATCTGTGGTGCCCGTTTCACCGATCAAGAACTCTTTGTCAAGCACATTCAGATGCATGAACAAGAACTCTATACAGATAATCCGCTTGCGGCCATGTTCGATACAGGTCCAGCCGATCCCAATCAATTCTATATGGATCGTGTTAACGATAATGGCGAGTATGCGTGTGATTTGTGTTCAAAGACCTTTACACAAATGACAGCATTTAAAGTACATAGGAAATGGCATTTCAGAGGTGATAACAAACAGAACGATGCCGATCATCTATCAGCGAATCAagtccacaacaacaacaacaacagcctgccacacagcaaatcccaacaacagaaccaactgaaatcgaacaacCATCCACATCTACTGGGATTACAAGCGGTGGGTTTGGTGCCCCGTCATTCGATCAATTCTTCGGCGCCGCATGCCCTGAACCGATCCCAGAAACGCAAACGAGAACTTAAATGCCAATACTGTCCGTCCACCTTCATAAGCAATAATAATCTACGTCGCCATCTCTTCGAACTGCACAAAAACGAAATTGGCAACTTACCCGAACCACCGAGAATCGAATGTGATCCACCGAACATGTGTCGTAAATGTAATGTTAAATTTGAATCGAAGGCCGAATGGATTGAACACAAGGTTGGAGAAGCGAGGGTAATGAAGCCATTCGGACCATTCCAATGGGGTTGTGATCTATGTGGTGCCTATGTGTCACGCAAAGAGAAACTTATCAATCATTTGCATAATCACATGAAAGAACAGGTGATAGTTCCAGTCGAATATAATGAGTCCGGACAGCAGAAGCCACAGCAACACAACAACGATAATTCCGAGGAACAACAGAATAAAGAATCCGCCCAAGAAATACatgaatttaagaaaattaaactgCCTGGTCTGCAACAAAAACCAATGGCTCAAATGGAGGATGACTCCCGGGACAGTGCCAAGGATCAATATGAAAACGATGAAGATGGTGATGGTGACAGTGAGCAGCAACATGAGTCAAACAATAATACACGACAAAATCAACAACACCAGGGCTATggagatgatgacgatgacgacgaagaggaagaggaagaagagttggaagaagaaatattggaaggagaatttgatgatttagctGTGGGAGCCCAGCAGACTGTGggtggcgaagaagatgaagaagtcgatttgggcgaagacgaggaagatgatgatgacgaggatgatgatgaagaagacgacgatgatgatgatgaggatgatgatgatgtggacgatgaagaagtggatgaggacgaccatgCAGCGCTAAGACAAAAGTCTGCCCCTCCCCCAGCCGCCCAACTGTCATCACAACAGCCAAAACCACAATCACGGCCCAATGCAAACTATTCCGAGgttgatgaagatgatgatgacgacgacgatgaggatgacgatgacaacgacagcgatgagttcgatgatgacgatgatgcctCATCAACGGAAAACCGTAAACCCAACAATGTTGTGGCCAATGCCGTTGTTAAATCCCGCTTCTCCTGTGATCTCTGCCAAGTGTATTTCGACACCCAGCTCGAACTGCAGAAACATGTAAAAATGCATTTCCTCAATGGACCCGGTTCGGTGACATTGACCGGCATTAAGACCTCCAAATCATCCTCATCCTCGAACAAGAGTCGAAGCAGTAGTAGTGATGTTTTGGCCGTCTCCTCATCATAG
- Protein Sequence
- MSDERLQQQNQQRRHNCCRLCLAPDNECISILNSYAADKEPLASKIHSCVSIKISSTDNLSLRICHACISYLNSWQSFKNRCLSAQNKQRSWLDGSSSPQKTKSNAEQQSQHTTTAISDNHSEDQQQKDEQSLASSILEGISTLKKRKSLTVYPLPAVQIKDEPMDAEDDYNNAKHNDESDEMVDPTMFLERTADEGEEPIMDSSSAYDYDNIRPPVDIAPLPAGTVIRMSTKEAACRACNLKFSTRANARRHEKNLHPHLFDTLEENDTTLNKQTAALNASLELQRAVAAAVAADACKLTSSGVITQQKYRHEVVTAFNNSCEVGYDYDNPEKYQHLLTDEKIVFLQQNDEFIRQYHAMTCRCCNRFYTTYKNFMAHMRKKYLTLPRNCCFNCLKLNDSKALFISHLKKRNCINLHRVLHSLMSKNANFAAAVSATVAAAPEKLRAKELLVNKMYECRLCPKTFRLKLEFRTHVYDEHADAQRKDINTTQCSFCGIDIEDPAERKRHYNNMDCIVTLRCVTCDTKHETQQKFMEHVQDKHMTNFGESTPFGLGNADNSPGKSSNVGGVGGASSTDESRNSFNVNLVNTSQPRAQYFSRMPQACPICGQQYNNYNNVLRHMESKHPDQLPQTYKCVKCGQGYPRLSNLREHMVSAHGADKARHTGFEYIVNADAVKAATDGGSSTGGNSHSQYTGRYDYVMKDLMSITNGGTLADDDGEFENSSKKMRFDGPGSNGGTPTNASPRECPICNAVFANNIGLSNHMRSHQSAANNSFSSNSKSLGGGNSLMHTTLSSGGTQAILKKSLEQAADRRFRRMRCRICQRRFSSKKSYRYHMLNDHQIRNVQFIKCKLCDAEFAYEKGLKVHMFKIHNTLLKDDMIIKQYECEICSIVYRTDVELQHHLANVHKKQGGAERTMSNDGDDYNMDESVGGTGGGGGADATAADLSGISTPVSVSGGAGGSGGDGSSGPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQIPEPSECVLCKKVFFDSQMLDHHIPTCNRKPITSANNETGGAGTQSSAAAIYKHKTGDDDEDDDDHSRDAHDTDAISTNLQATAGSMKIKLPEVACTICGARFTDQELFVKHIQMHEQELYTDNPLAAMFDTGPADPNQFYMDRVNDNGEYACDLCSKTFTQMTAFKVHRKWHFRGDNKQNDADHLSANQVHNNNNNSLPHSKSQQQNQLKSNNHPHLLGLQAVGLVPRHSINSSAPHALNRSQKRKRELKCQYCPSTFISNNNLRRHLFELHKNEIGNLPEPPRIECDPPNMCRKCNVKFESKAEWIEHKVGEARVMKPFGPFQWGCDLCGAYVSRKEKLINHLHNHMKEQVIVPVEYNESGQQKPQQHNNDNSEEQQNKESAQEIHEFKKIKLPGLQQKPMAQMEDDSRDSAKDQYENDEDGDGDSEQQHESNNNTRQNQQHQGYGDDDDDDEEEEEEELEEEILEGEFDDLAVGAQQTVGGEEDEEVDLGEDEEDDDDEDDDEEDDDDDDEDDDDVDDEEVDEDDHAALRQKSAPPPAAQLSSQQPKPQSRPNANYSEVDEDDDDDDDEDDDDNDSDEFDDDDDASSTENRKPNNVVANAVVKSRFSCDLCQVYFDTQLELQKHVKMHFLNGPGSVTLTGIKTSKSSSSSNKSRSSSSDVLAVSSS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01375100;
- 90% Identity
- -
- 80% Identity
- -