Mdom009409.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Musca domestica
Gene Symbol
Zfy1
Assembly
GCA_000371365.1
Location
Scaffold609:31441-35926[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.016 0.79 10.0 0.2 3 23 17 37 16 37 0.96
2 16 0.00013 0.0062 16.6 3.3 2 23 95 117 94 117 0.95
3 16 4.2e-06 0.00021 21.3 0.6 1 23 123 146 123 146 0.97
4 16 0.00037 0.019 15.1 0.3 2 23 158 180 157 180 0.96
5 16 0.0003 0.015 15.4 0.8 1 23 276 298 276 298 0.98
6 16 0.00011 0.0055 16.8 2.9 1 22 304 325 304 326 0.90
7 16 0.15 7.4 6.9 3.2 1 23 335 357 335 357 0.96
8 16 0.03 1.5 9.1 3.0 1 19 365 383 365 385 0.94
9 16 0.18 8.7 6.7 0.4 1 23 423 445 423 445 0.97
10 16 0.049 2.4 8.5 3.4 1 23 451 473 451 473 0.96
11 16 2.5e-06 0.00013 22.0 2.1 1 23 479 502 479 502 0.97
12 16 0.0011 0.054 13.7 8.7 1 23 508 530 508 530 0.99
13 16 0.00031 0.015 15.4 5.1 1 23 588 610 588 610 0.98
14 16 0.0003 0.015 15.4 1.6 1 23 616 639 616 639 0.97
15 16 1.8e-05 0.00087 19.3 0.3 2 23 650 671 649 671 0.97
16 16 0.00022 0.011 15.8 1.7 1 22 677 700 677 703 0.92

Sequence Information

Coding Sequence
ATGGTGcacatagaaatattgagtatTGAACAATTACCACCAAAAATCTGTGTTATTTGTAACATTGTTATCAGTGATGCCCAAGATTTGTGCAGACATTATCAAGAGCATCGTCTGAAATATCTTAGCAATATCGATGATGATGACATGTCGGAAGAAACTGCATCAAATGATTCATTCCAGTTGGATGAATTTCTAATTTTTCCCAGCAGCAAAAACCTGTCGCAGAACACACCACAGAGAGAGGAATCGAAGGTGAAAGGAAAAAGCTCGGAATCGCTTACATGTCCAATTTGCAATAAAAAGTTTACCCATTTGTCTTCCCGCAATCGTCATGTTAAGCAGCAACACGAACAACAGCAAAGATTTGAGTGTGATCTATGCGACTTAGATTTCTCGACCCCATTTAATCTACGAAATCATCAGAAAAAGATCCACTTTGCCAACTTCGTAAAAATTGGTAATGTCATAAAATGTCCACATTGTCCACGTAAATATAAAATAGAGGCTGCTCTGATTAAGCATATACTTTCCACACACAAGAAAGATAAACGCCCCAATGAGGTGCCCGAATCTCAAGCAGAAGAGTTAGAACCACTGGATAATGATCCACAAATTTTGGCGGATAATGTTCTAAATGAGCTAAAGCAATTACACAGTGCCCTTTCAATAACTGATGGCGACAATGGAACAACACTGCAAACAAATACCGAAATTGATGAGGCTTTTGTTGATCATGTTATAATTAAGGATCGCCTTAATCCCCAGAGGATTGTGGTGGCAATGTACAAAGTACAGAGAATCAAAAGAgacaaatatttctattatattTGTGAATTTTGTGGCAAAGAATTTCGCAAGGGTAATGGTTATTTAAGGCATCGTCGCGTACACACAAAGTATCGCCCATATATTTGTGTTGTgtgtaaaaaatcattttccacACAGACCGAATTGAAACGTCATTGTGTGACCCATAGCCTGGAGggcaaacaaaaattgtataaatgtcCCCAGTGTTGTAAACAATTTGCCACCATTGCCCAATTCGATAAACATTTAAGttTCCATGCTCCAGAGTCTGTGATCGTGTTTAGCTGtcaaaaatgtcctaaaacatTTGATTCATTAAATAAGTATTTGAAACACAGCCACGAGGAAAATGATCCTGAGTTGAATATGCTTAAAACACTGTTGCCCGAACCACTATGTCTTTTAAATGGCACAACATCAGAATACTTATTGCAAGAGAAACTAaagccagcatttaaatgcttaATTTGTGGCTTACAAATGGACAATTTACTGTCATTAAAACAGCATGAGCAACGCCATAGAAATTTATCGAAACATTGTTGTCGCATATGTAAAAGATTCTATGCATCCGAATTATCTTTAAGAATTCATGCCAGAATTCATTCAAGCTTTCGAAAGTTTAACTGTAACCAGTGTAGCCTTACATTTCGCAGAAGCTATGATTTAAAACGTCACCAACTAACAGCCCATTGTAAGGAAAAGAATTTCAAATGTCGCTATTGTGATAAACAATTCAAAACTAAACAGTATTGCCGTAAACACATGATGACACATCTTAAACAACTGATTGAATCAAATGAACAGAAACAGCTGAATAGGACACGGTCGGTGCAAGCCATTATACATACGAATGAATCTGAAATTGTTGTAAGTGaaataaaaatgccagtaaaaaatctaaactccaacaaatcactggacctacaaaaggaaaaacaaatgcTATATAGTTGTAcaatttgttgcaaaatgttcCAATATAAAtctcaattaaaaaaacacattctaACTCACAGTACGCTGTTGCCATACAAATGTGAGCTTTGCCAAAAAGGCTTGAAATCAGCACAATCTTTAAGGCAGCACATGTTCAAACGTCATGAAGAgggggggCGAGAGGTGACCAAGGTAAAGTGTCAAGTGTGTGGTAAATTGTATGCAAATAAGAAATCCCTTAATGTACATATACGCTTGCATACGAATGAAAGACCTTTCAAGTGCGACTTTGATTTATGCAATCAAACGTTTCGTACTTCAGGCCATCTTGTGGCACATCAAAAGGCAAAACAACAtagtttataa
Protein Sequence
MVHIEILSIEQLPPKICVICNIVISDAQDLCRHYQEHRLKYLSNIDDDDMSEETASNDSFQLDEFLIFPSSKNLSQNTPQREESKVKGKSSESLTCPICNKKFTHLSSRNRHVKQQHEQQQRFECDLCDLDFSTPFNLRNHQKKIHFANFVKIGNVIKCPHCPRKYKIEAALIKHILSTHKKDKRPNEVPESQAEELEPLDNDPQILADNVLNELKQLHSALSITDGDNGTTLQTNTEIDEAFVDHVIIKDRLNPQRIVVAMYKVQRIKRDKYFYYICEFCGKEFRKGNGYLRHRRVHTKYRPYICVVCKKSFSTQTELKRHCVTHSLEGKQKLYKCPQCCKQFATIAQFDKHLSFHAPESVIVFSCQKCPKTFDSLNKYLKHSHEENDPELNMLKTLLPEPLCLLNGTTSEYLLQEKLKPAFKCLICGLQMDNLLSLKQHEQRHRNLSKHCCRICKRFYASELSLRIHARIHSSFRKFNCNQCSLTFRRSYDLKRHQLTAHCKEKNFKCRYCDKQFKTKQYCRKHMMTHLKQLIESNEQKQLNRTRSVQAIIHTNESEIVVSEIKMPVKNLNSNKSLDLQKEKQMLYSCTICCKMFQYKSQLKKHILTHSTLLPYKCELCQKGLKSAQSLRQHMFKRHEEGGREVTKVKCQVCGKLYANKKSLNVHIRLHTNERPFKCDFDLCNQTFRTSGHLVAHQKAKQHSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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