Mdom004959.1
Basic Information
- Insect
- Musca domestica
- Gene Symbol
- -
- Assembly
- GCA_000371365.1
- Location
- Scaffold20318:19538-34944[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 27 9.6 4.7e+02 1.3 1.2 3 14 305 316 303 326 0.76 2 27 0.013 0.65 10.3 0.3 1 23 332 355 332 355 0.93 3 27 4.5 2.2e+02 2.3 0.8 1 23 419 442 419 442 0.85 4 27 9.1e-05 0.0045 17.1 4.8 1 23 448 471 448 471 0.97 5 27 0.00013 0.0064 16.6 1.2 2 23 502 523 501 523 0.97 6 27 0.057 2.8 8.3 3.4 1 23 598 621 598 621 0.96 7 27 0.067 3.3 8.0 0.8 2 23 629 650 628 650 0.97 8 27 0.00048 0.024 14.8 1.3 1 23 692 714 692 714 0.98 9 27 0.0017 0.082 13.1 0.4 2 23 726 747 725 747 0.95 10 27 0.014 0.69 10.2 2.0 1 23 819 841 819 842 0.96 11 27 0.0054 0.27 11.5 0.4 1 20 849 868 849 870 0.94 12 27 0.082 4.1 7.8 0.2 2 23 882 904 881 904 0.94 13 27 0.00032 0.016 15.3 0.4 2 23 919 940 918 940 0.97 14 27 4.2e-06 0.00021 21.2 2.6 3 23 948 968 946 968 0.98 15 27 1.6 80 3.7 1.9 1 23 1119 1143 1119 1143 0.93 16 27 0.14 6.9 7.0 1.1 1 23 1180 1203 1180 1203 0.96 17 27 0.00052 0.026 14.7 2.6 3 23 1221 1242 1220 1242 0.94 18 27 0.036 1.8 8.9 4.3 3 23 1251 1272 1250 1272 0.93 19 27 0.12 5.8 7.3 0.2 2 20 1298 1316 1297 1318 0.93 20 27 0.00012 0.0059 16.7 1.9 1 23 1365 1388 1365 1388 0.97 21 27 0.51 25 5.3 1.8 1 23 1425 1448 1425 1448 0.92 22 27 0.15 7.3 7.0 6.6 1 23 1479 1502 1479 1502 0.97 23 27 7.1e-07 3.5e-05 23.7 0.6 2 23 1531 1552 1530 1552 0.95 24 27 2.4e-06 0.00012 22.1 0.6 1 23 1558 1580 1558 1580 0.99 25 27 1.8e-07 9e-06 25.5 4.5 1 23 1586 1608 1586 1608 0.99 26 27 3.4e-05 0.0017 18.4 4.2 1 23 1614 1636 1614 1636 0.98 27 27 0.13 6.2 7.2 1.0 1 22 1642 1663 1642 1666 0.88
Sequence Information
- Coding Sequence
- atgcaatcatatgcatgcatttttttcaaaattgttcatttgacaacatctcatatCCATCTCATGTATATCCAGAAATCAGAGTTGGGAATCtttttttATTccgtgaaatttgacaagACAAAGgcattagaaaataaaaaaaattggggaaatACGAAGTTAAATTTTAGTGTTTTAACAATAATGAACGGAATTTGCCGGACATGTTTCGATCCCGGAGAAAAAGAGCTTTACAATCTGGTCGATGAAGATGAGACAGATTCGAAGACGCTGCTAGAACTATTAACAGAAGTCGTAAAGTTGGAGataccaatagacgGTCCGCTACCGAAAATGATTTGTGCTGACTGCACGAAAAGTCTTAAAGAGGCGCACAAATTTATAACTCGGGTTCATCATGTAAATGAGAGATATATGAAATTTCTCGCAGATGGCCAGGAAGATCCCCTTTTAGAAAACGATGTGGGGAACAAACTTTCGGACTGTTTGGAAGAGTCTGCGATTGATATGCCGGTTGACCACTATTTGGACGACATTAAATTAGAGGTGGTGGGGGACCAGTATGGTATTTTGCTGTTGGATAAAGATGTTTCCGCTCAGTTGGAGAAAAATGacAAGGTATCATCGGAGTTCATAAAAAGCTCCAACAGATGCACTCTTAAGGAAATGCAGCATGAAAGTGATGATGAAATATATGAATCTGGAAGAGACAGCCCCCTGGGTATTGGCGACGAAAGTAATGTCCATGGTTATGGGGAAAACGATTCGTCTGACGATGACTACGAACCcacaaaaagaataaaatcagaAGAGGGATACAGGAAACCCTCttcaaaaagaacaacaaagacGAAAAGTCCACTTTTAGACTGCTATAAAAGCATCAAACATATTGGAGATCGATATGGATGTTACATGTGTGACCAAACATTTCCCCAGCGCAAAATCTGCGCTCGACATATTGCTTCAAAACATCTAAAGGAAAGTATATTTCTGTGTGAATACTGCCCTGAAGTATTTAACCGAGAGGACAAGATACGACTGCATGGAAAACGCATGCATCCCGACAAACCCAGGATATTGGAAGCAGAGGAGGTGTCACATATTGTCAATAACTCGGAGAAATCGTCCACTGAGGAAGAGGATTACCATCAACGGGATAAAGATTCTAATAAAAGGCCACAAAGGAAACGAAGAGTTGGTCGACAAGCTCCGGATTACTTCGACAAAATACGGCAAGTGAACGACCGATTCGCATGTATTATTTGTGAAAAAACTTTCTCCTTGCGAAAAGACTGTGGCCGACACATAGCATCTATACATTTAAGAGAAATAACCTTTCCATGTGAGTATTGCGGCCAGCATTTCAGCCGTAAAGATAAGGTGAGGCATCACATTAAGCGCATGCATTGCGATAAATCCACGTATCCTAAGAGCAAGCGCAAGGAGTGGATGTTTGGAGACCGGTTATACAGTAGACCAACGGAATGGCTAATGGTGGAGTGCAAACTCTGCAGTATGCGTTTTAGTTCTactaaagaattaaaaaatcacATGGAAACTCACAACAAAATCGATTCTATGATACATCTTCGAATGGACAGTGAGGTTATTACGCATTTGTTCCCGAATGAATTCAATTTGGGCAGCGTTAAAGAATTGATATGTAAGGACATTGAGGAAGGTCGGTGGTTTCAATACTACGCAGTTTTAAATGAATTCTCGTATGAAATGTCTATAAGCGACACTGAACCAGAGGATTTAAACGCGGAAATGACAATGCCTAAATATAAGTGTGAAATATGTGGTCTTGAGTGTCGATTTCAACATGAGGCGTTCAACCACTTAAAACAGGATCATGAAAATGAAGAGATGCCTCTGAAATGTGGGCTATGTAAATTAGATTTTATATCGTCGAAAATGTTTGATCGCCACTCCCGTATTCATTGCCGTAACAGGAGTAAAATTCTGCTGTGTACCAAATGTCCTGCCAAATTCGTATGGCCAGAAAACATGAGAAACCATAACTGTGCATCAAAACCCGAGATCAACAGCGAAGACAGGGAGATTTTTAAATGTGATATTTGCAACCGACCATTCGAAgtcaaaactaaatttttgaaacatttagaGAGACATGAATTAGAAGATAGCTCAAACAAAGCTATTATTCGATGTGGCCTCTGCCCACAAACattcgaaaaattgaaaaatctccGAGATCATATAACACAGCACGCGGACGGTGTAACTGGCATCGATTTTCACAATGGCATTTATTTTAAGAGATTTGAACGGTCAAAAACTCACGACCGTGCATTGATACAACAGGAAATACAAAATGCATTCGAGAAATCTCAAATAAGCCGATTCTATAGGGCTTTAGACAAGGATGGAATGGAAATGGACATTATGGATTCCGACAGCGACCCTGAGTCAACATCTTTAATATACAAATGTGAACTATGCCTCACGATGTTTGGAAAGAGGAAGGCTTTGTTGAATCACCAAAACGAACATCATTTAGGAATTCCCTTACCGTATGCGTGCAAGGATTGTACAAAGGAATTCGTAAGTGATGACTTGCTTCAGCAACATAAATTTAGGGAATGCTGGAATGAATTTCGACGAGTTGCGCAGCAATGTGAATACTGCAATGCTCGTTTCATATGGCCGAATAATTTGGTTAAGCACAAGGAAATAAAGCACAAACATCAGAAACAACCTCGCCCAAAACGTGCTAGCACTTTGAAATGTGAATATTGCGAGAAAGTGTTCATTTGGCCGAAAGACTTGGTTCGACATCGAAAAACGCACACTGAAGGAAAAAAGTTTGGCTGTCCACACTGCAAACGAAGGTTCCAGAGAAAGGATAACCTTCTCGCTCATATACGTACTCACGACGCTAGTAGCATGCCATTGATAACAAACTGCAATAAGGCTATTGAGTACATTCTTCCACACTTAGCTAAACCTCACGGATGCAAGCGTATACGTTGCATGATATGTTTTTCAGAACACGCACACATTCGCGATTTACGTTCACATTTGCGGTCTCACCAATACGAGATTAACTTCGAAAAACGCAAGGAAAACGAGAGCATAGatcatatatcaaaaaaaatctatcccgAAGAAGGGTCAATGTGCGAGGTGGACTTGTTCAGAAAAATTTCCGCTGATATTGCAGCTGAACGGAATTTGGAACGGTTCTACTCAATCACAAACGAATACGGCTATGAAGTTAGTCTGGACAGTTCGGAAACCGAGAGTGGTGACTCGGAGGATGATAGAACCGATGGTAAAAGTAATGATAAGAATGCAATTAGCTTATTAAAATCAAACCGTGTCTACACGTGCGACATTTGCCCGCAGTTAACTTTTGATCGGAAGTACAAGGTTTATGAACATCATCAGAATGAACATAAGTGGGAAGATGGTCgacatatttgtatttattgcaACGCTCGTTTCTTGTCATCACTTATGTTAGAACTACACTACAAAACTCAatgcaaaaacacaaaaaaacgaCACACTTGTCGACGTTGTCCTCTTCGTTTCATGTGGAGGGACAACCTTAAGACACACATTGCGATGGAGCATCCGAACGAGGCAGCAAAAGAGGTAGATACAAGCCGCactttaatgaaaatttgtCCACTGTGCCAAACCAAGTTCTGCACCCAAAAAGAACTAACGCAACATATGTCTTTAACTCACCCAGCGGAGTCAGAGCTGCGACACTGCTTCTTATGTCCCAAAACCTTCTATACTTTTGAACACCTTAATGAGCACTTGACACAACAGCATTGTTTAACCCAAGATAGTGTCAATAGCGTCGAAAGCATTGCCCCATTGCTCTGTCCTAACGGGAAGAAGTTTATTAAGTGCAAAATTTGCTCTTCGGATTTCCGAACAATGGCTAATCTTAGTGATCATTATTCGCTTAGTGTATGCACAGTCCAACCATCGGCTACTTCTTATTCGATAACAAACCAAAAGGGATTCGAATTGCACTTAGAGTTGGATTCCGAGACGGAAGCAGAAGAAAATACCCACGCTGAAGCCAAAGATATTGACCAACGATACATGTGTTCACTGTGTAACTTGTCTTTTGGGCGCAAATACCAaatgactcagcaccaacgaTCAATGCACTTCTACGAACATTTGCctttgaaatgtgaaaaatgcatttttagaaCATCGTGCCAGAAACTTCTAGAATATCACACATCGACTCAGTGTTACAATGTAGACAAACAATATCATTGTAGCATTTGCAAATTCAAGTTTATGTGGCAAGAAAATTTGGAACTTCATCTGGACttgtttcataaaaaaagtGACGAGCAAGTCGATGATCCAACAACTGCGACAATCGGAAACCATAGTCAGATAGAAACCCATAAAGGTGAAACAAACATATTTGAGTGCATGCAGTGTCATCGTCGTTACAACCGTAGAGATCGTTACAAGgcacattttagaaaatttcataacAATGAGACTTTTAGCCAAGATGAATCCCTGAAAATCCGAGAGCGTGGAAAGTCTTCGCCaaataataaaactaaaaactttTTATGTGCTTTTTGCGGTGTATCATTTTCAAACAACTCAAATCTTACCGTTCACATGAGACGACATACGGGTGAGAAACCTTTCAAATGCGATCTTTGCGAAATGGCATTTCCGCGATCCTCCGACCTGCAGTCTCATCGACGCACTCATACTGGAGAAAAACCTTACAAATGCTCTCATTGTGAAAAATCGTTTTCAAGacaatataaattaaatgtgCATATGCGCATTCATACAGGCGAGCGGCCATATTCTTGCACGTATTGTGCAAAAAGTTTTACTCAGTCAAATGATCTAACTCTACATCATCGTCGACACACCGGGGAAAGACCTTATTTGTGTAACATATGTGGAGAAGGTTTTATTTGTGCAACATCTCTAAAGCAGCACAAAAATTCCAAAGGCCACTATGAAACCGCTGATTCGGAAAATGAACGTggacaaaatttatcaaatttcgagatgaACTTCTGA
- Protein Sequence
- MQSYACIFFKIVHLTTSHIHLMYIQKSELGIFFYSVKFDKTKALENKKNWGNTKLNFSVLTIMNGICRTCFDPGEKELYNLVDEDETDSKTLLELLTEVVKLEIPIDGPLPKMICADCTKSLKEAHKFITRVHHVNERYMKFLADGQEDPLLENDVGNKLSDCLEESAIDMPVDHYLDDIKLEVVGDQYGILLLDKDVSAQLEKNDKVSSEFIKSSNRCTLKEMQHESDDEIYESGRDSPLGIGDESNVHGYGENDSSDDDYEPTKRIKSEEGYRKPSSKRTTKTKSPLLDCYKSIKHIGDRYGCYMCDQTFPQRKICARHIASKHLKESIFLCEYCPEVFNREDKIRLHGKRMHPDKPRILEAEEVSHIVNNSEKSSTEEEDYHQRDKDSNKRPQRKRRVGRQAPDYFDKIRQVNDRFACIICEKTFSLRKDCGRHIASIHLREITFPCEYCGQHFSRKDKVRHHIKRMHCDKSTYPKSKRKEWMFGDRLYSRPTEWLMVECKLCSMRFSSTKELKNHMETHNKIDSMIHLRMDSEVITHLFPNEFNLGSVKELICKDIEEGRWFQYYAVLNEFSYEMSISDTEPEDLNAEMTMPKYKCEICGLECRFQHEAFNHLKQDHENEEMPLKCGLCKLDFISSKMFDRHSRIHCRNRSKILLCTKCPAKFVWPENMRNHNCASKPEINSEDREIFKCDICNRPFEVKTKFLKHLERHELEDSSNKAIIRCGLCPQTFEKLKNLRDHITQHADGVTGIDFHNGIYFKRFERSKTHDRALIQQEIQNAFEKSQISRFYRALDKDGMEMDIMDSDSDPESTSLIYKCELCLTMFGKRKALLNHQNEHHLGIPLPYACKDCTKEFVSDDLLQQHKFRECWNEFRRVAQQCEYCNARFIWPNNLVKHKEIKHKHQKQPRPKRASTLKCEYCEKVFIWPKDLVRHRKTHTEGKKFGCPHCKRRFQRKDNLLAHIRTHDASSMPLITNCNKAIEYILPHLAKPHGCKRIRCMICFSEHAHIRDLRSHLRSHQYEINFEKRKENESIDHISKKIYPEEGSMCEVDLFRKISADIAAERNLERFYSITNEYGYEVSLDSSETESGDSEDDRTDGKSNDKNAISLLKSNRVYTCDICPQLTFDRKYKVYEHHQNEHKWEDGRHICIYCNARFLSSLMLELHYKTQCKNTKKRHTCRRCPLRFMWRDNLKTHIAMEHPNEAAKEVDTSRTLMKICPLCQTKFCTQKELTQHMSLTHPAESELRHCFLCPKTFYTFEHLNEHLTQQHCLTQDSVNSVESIAPLLCPNGKKFIKCKICSSDFRTMANLSDHYSLSVCTVQPSATSYSITNQKGFELHLELDSETEAEENTHAEAKDIDQRYMCSLCNLSFGRKYQMTQHQRSMHFYEHLPLKCEKCIFRTSCQKLLEYHTSTQCYNVDKQYHCSICKFKFMWQENLELHLDLFHKKSDEQVDDPTTATIGNHSQIETHKGETNIFECMQCHRRYNRRDRYKAHFRKFHNNETFSQDESLKIRERGKSSPNNKTKNFLCAFCGVSFSNNSNLTVHMRRHTGEKPFKCDLCEMAFPRSSDLQSHRRTHTGEKPYKCSHCEKSFSRQYKLNVHMRIHTGERPYSCTYCAKSFTQSNDLTLHHRRHTGERPYLCNICGEGFICATSLKQHKNSKGHYETADSENERGQNLSNFEMNF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -