Basic Information

Insect: Musca domestica
Gene Symbol: -
Assembly: GCA_000371365.1
Location: Scaffold19226:27742-67921[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.18 9 6.7 1.4 2 23 30 52 29 52 0.94

2 22 4 2e+02 2.5 1.1 2 23 455 477 454 477 0.90

3 22 0.091 4.5 7.6 0.2 2 23 484 505 483 505 0.96

4 22 1.4e-07 7.2e-06 25.9 0.6 2 23 512 533 511 533 0.97

5 22 7.7e-05 0.0038 17.3 1.4 1 23 539 561 539 561 0.97

6 22 0.47 23 5.4 3.1 1 20 567 586 567 589 0.93

7 22 0.0013 0.066 13.4 5.7 1 23 595 617 595 617 0.97

8 22 3.4e-05 0.0017 18.4 1.0 1 23 623 645 623 645 0.98

9 22 0.41 21 5.5 3.2 1 23 921 944 921 944 0.93

10 22 0.062 3.1 8.1 0.1 2 23 951 972 950 972 0.96

11 22 0.04 2 8.7 0.6 2 23 979 999 978 999 0.93

12 22 5.4e-05 0.0027 17.8 0.7 1 23 1005 1027 1005 1027 0.98

13 22 0.003 0.15 12.3 0.6 3 23 1035 1055 1034 1055 0.98

14 22 2.9e-05 0.0014 18.6 0.9 1 23 1061 1083 1061 1083 0.97

15 22 0.0067 0.33 11.2 0.8 2 23 1115 1137 1114 1137 0.96

16 22 0.078 3.9 7.8 1.7 1 23 1496 1519 1496 1519 0.91

17 22 0.36 18 5.7 0.6 2 23 1525 1546 1524 1546 0.93

18 22 5.1e-05 0.0025 17.9 0.1 2 23 1553 1574 1553 1574 0.96

19 22 6.3e-05 0.0031 17.6 0.8 1 23 1580 1602 1580 1602 0.98

20 22 0.011 0.53 10.5 3.6 3 23 1610 1630 1609 1630 0.97

21 22 8.3e-06 0.00041 20.3 0.6 1 23 1636 1658 1636 1658 0.96

22 22 3.8e-05 0.0019 18.2 1.5 1 23 1664 1686 1664 1686 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.18	9	6.7	1.4	2	23	30	52	29	52	0.94
2	22	4	2e+02	2.5	1.1	2	23	455	477	454	477	0.90
3	22	0.091	4.5	7.6	0.2	2	23	484	505	483	505	0.96
4	22	1.4e-07	7.2e-06	25.9	0.6	2	23	512	533	511	533	0.97
5	22	7.7e-05	0.0038	17.3	1.4	1	23	539	561	539	561	0.97
6	22	0.47	23	5.4	3.1	1	20	567	586	567	589	0.93
7	22	0.0013	0.066	13.4	5.7	1	23	595	617	595	617	0.97
8	22	3.4e-05	0.0017	18.4	1.0	1	23	623	645	623	645	0.98
9	22	0.41	21	5.5	3.2	1	23	921	944	921	944	0.93
10	22	0.062	3.1	8.1	0.1	2	23	951	972	950	972	0.96
11	22	0.04	2	8.7	0.6	2	23	979	999	978	999	0.93
12	22	5.4e-05	0.0027	17.8	0.7	1	23	1005	1027	1005	1027	0.98
13	22	0.003	0.15	12.3	0.6	3	23	1035	1055	1034	1055	0.98
14	22	2.9e-05	0.0014	18.6	0.9	1	23	1061	1083	1061	1083	0.97
15	22	0.0067	0.33	11.2	0.8	2	23	1115	1137	1114	1137	0.96
16	22	0.078	3.9	7.8	1.7	1	23	1496	1519	1496	1519	0.91
17	22	0.36	18	5.7	0.6	2	23	1525	1546	1524	1546	0.93
18	22	5.1e-05	0.0025	17.9	0.1	2	23	1553	1574	1553	1574	0.96
19	22	6.3e-05	0.0031	17.6	0.8	1	23	1580	1602	1580	1602	0.98
20	22	0.011	0.53	10.5	3.6	3	23	1610	1630	1609	1630	0.97
21	22	8.3e-06	0.00041	20.3	0.6	1	23	1636	1658	1636	1658	0.96
22	22	3.8e-05	0.0019	18.2	1.5	1	23	1664	1686	1664	1686	0.97

Sequence Information

Coding Sequence: ATGGATGACGTTGTTAAATTGGAGTACCTTGTGTGCGGGGAAATACTGGCTCCAATTTCCGTCAATGCGAAGGAGCAATTCTTCTTGAAATGCCTGGAATGCGATGAATATTTTACGATGTTGGAAGAGTTTATAATGCATTATCAGTACTGTCATAATGATAAATTTAAGATGACAATGCATTCTCCCGACACGAGTAACGCCCAATATCAACGTGAAGTGGATATACAGTATGCAGATGAATGCCAGGAAGATCGTGACATCCATGAAGAAAATGATGTTGAAGAAGTCAAGgatgaaaatgaagaaaattatgAAGCTGAATATGCGTTGGTCAATGAAAGTCAAGATAATATCGACGAGGATTTTGGGGAGGAAGAAGTTCACAACTTTAAAGACAGTGAGGGAGAGgatggaagtggtgatgatgataatgaaattggtgataatgaaattgatgataatgaagttgatgaagatgctgaaattgagatgTATGACGAAGAAAACGACAAAGCTGACGATGACGACGAACTACTGCAGGACGCCGACGATAGCCAAGAGGAATACGACGATGAAGGATCCCAAGATTTTGATAGGATTGAAACATCTAACAATGATGACGAAGATCCTCTAGCCCACACTCACAAAGAGGAAATTAAGAAAGCCCGTGCATTTGTTAGTAAATTCCTAGAATGTGACGATAATTGGAAAGCCTTTATGAGAGCATATGAAAAAGTACCACAACTATGGGACCCGaaactatttccaaaaaaattaaacaacgaTGAACGTAATGCATATCTGCAGAAAATTGCAAACGAAATAAAAAGTGAACGAAACATAGAGCTTGATACAAACCTTGTTGGTCTTACAACAGTTCGTGTGCGACAACATTTCAGAATCAGAATAAACCGCTTTAAAACGGCCGAGGATCGTCACGATGCAATTGAGAACAAAATTGTGCCTAAATGGTATTTTGAGGCATACGCATTCTTAGAACTGACCCTGGAACAGCTATCTATCGTCAATTTTGATTCACAACGAAAGCATTTACGAAAagaacaaattttgcaaattattcaaatatatcaaAGATTTCCAAATCTATGGAACACAAACTTGGCCGAAAATGTTTGTTTCAATAAACGACAGGAAGCACTTGGGGAAATGTCCCAAGTAATACGCCGTGAAATGGGCTTGACAATCAAAGAGacatccttaagaaaatatttgcaaagtttgcatgTCCATTTTGCCAAAGAGAAGAGCTTGCTGCTTGATAACCAAGACAAGAAGCCGGAAAGCGAGTTGTTATACTACGATCACATGAAATACCTGAATGATCACGTTGGTCCTCTTATGTGTGAGTTTTGTGGGCGGAAGCATAAAAGTCCGCTGTTTTTAAAGGTACATATCTATGAGTCGCACCACCGCGATGACCCATTAAGATGTCCAATATGCAGCAAGGAATATGAACACGTTCAGCCCTACGTGGCCCATGCTCGAAGACACATGGATGATTTGCAGGACGAATGTAAGGAATGTGGTAAGCGCTTCATAAGACTTGCCGATCTCCGAACACATATGCGTACCCATACCGGTGTTAGACCATTCTTTTGTGATGTATGCGGAGCATCGTTTACCAAACGTTATTCTCTGACTGAGCATAGCCGTCGCCACGAAAAAGTctacaaatttttttgtgacatttgtTCAAAGGGATTCTATGAAAGAGCCAAAATGAACAGGCACAAGATTTGTCATTCGGATATACGCAAATATTGCTGCAGCATATGCGGCAAAGCTTTTAAGACGCGAAGACACACAAAAATACACGAATCCACTCATGCAGATTCGCGTGAGTTCCCATGTCCCCTgtgtggaaaattatttaaaaataaaattggagttACGCATCATCTGAGAACTCATCGTAAGAATATGGAGACCGTATTGAGTCCGTTTACAATGGATCCTCTAGAAAAAACTCTGCAGGGCACAAATAGTAACAACGATGTTTGCCATGCtgaaaaatcaattgaaaaaactTTTTCGGACTGTGGCGATGAGTTGATGGGCGAACATAGTAAATCATTTGTCAAGGAGTTCTTAAAATGTGATCTTAACTATAAAGCAATTTTATTCGCTTATCAAAATCAACCTAGCCTTTGGAATCGAAATCTATTTCCAAACAAGTTAAACAACGATGAACGGAATTTATGTCTGAAAAACATTGCACTGGAATTGAAAACTGCACGAAACATTGAATTGGACACGAGCATGGTAACCAGACATACCTATTGTGTTAAGTTGCGACGTTACAAAACAATTGAGCAACGCAAGGCAGCGGAAAGAAACAAAATTGTACCTGGCTGGTATTTTAAGCAATTGGCATTTTTGCAGCCAATGATGGATCATTTTACAATAACCAAACTGGATTCACAGCGGACAAATCTGACAAAGGAGCAAATCATACAAATACTTGAGATATACAAGAACTTCCCAGTTCTATGGAATACTTCATTGGTTGAAAACGTTTGTTCCAACAAACGACAAGAGGCTCTCGAACGAATGTTGAAGCCAATTCACAAAGAAATGGGCTTAAAAATTAATGTTAGtattttgcaacaatatttggaTAGTATTCATGCACATTTATCCAAAGAGAAGACCATgcttctcaaaaacaataagaatAATGAAAACATTTCCATGTACTATGATCACATGAAGTTTTTACACGATCATGTTGGGCCTTTTTGCTGTGGCATTTGTGGGCGAAGGAATAGAAGCCCACTTCATTTAAAGGTGCACATCTATCAGAAACATAATCGCAACGATCCGCTTCGATGTCCAATGTGTAACAAGATTTATCAGCAGATGGAACCCTATGTCGCACATGCCAGACGCCATATGAATGACTTACGGGTCGAATGCAAGGAATGTGGAATGTTCATAAGACATGCCGATCTGCGAGTACATATGTATACTCATACCGGAATAAAGTCATATTGTTGTGAAGTATGTGGTTCTGTATTTACCACAGCTTCAGCGTTAGTTGATCACAAACGTCGCCACGAAAAGCTGTAtaaagtattttgtgaaatttgttcGAAGGGATTTTACTACGATGAAAAGTTGAGAGAACATATGaccacacataccaatatacgCAATTATGCATGCGGTATTTGTGGCAAGAAATTTAAAGCCAAAAAGACACTTAAGGCACACAAATCTACACATGAGGAAGGCCTAATGGAGgaatatattgaatatattctttgtggagAAATATTAGTAGCACCTGCGATagattcgaaagatcaatactGCCTGAAATGCAACGAATGCAGTGAATACTATTCAACATTGGACGAGTTTATTGCCCATCATCAATCGGACCACAGTGTTGATGatctggaaaatatttcatcATCACCTGCTTCAGAAGTGGAATGCAATGaggaatatttagaaatatattcACCGCTATCCGTCAAGGCGGAGCATTCGAATGATGGCTGTGAAGTAGCACCTCCACTGTCTCCAACAAGCTACAGCGAAACACAAACACAcgataaaaatatggatgatgGCAGTACAAAATCTGAAATTGATGACGAGGAAGGGTTTAAAGGATTTGAAAGCGAAGGTATGGCCGGAGATGATGAGACGGACCCTTTAGATCAACCACAGTGTGAGCGAACAGAAGATCCTATTAATGATGAAGACAACGATAACGCATGTTTTGAATCAGAAGCTGAGTGGGAACCAGAGGACAACAAAACTAAGGTGTTCGTGAGTCAATtcttgaaatgtgaaaaaaatttcctaacaTTTATAGAGGCCTACAAAAAGCAACCTCGTCTATGGAATTGGAAGCAATATCCGTCAAAGCTTAACTCTAGTAAAGAGCGTGAAAAATATTGGTCGCAAATTGCCGcagaaatccgaaataatttaaacattGAGATTACCTGCAAGTACGTATCAGCAGTAATAAGACGAATTCGAAATGGTTATGCCATTAAGTTGAATCGCCTCAAGTCATATGAGCAGCGTGGTGGAACACTTAAAAGCAGGAATATTCCTCAGTGGTACTTTAACAAGATGCAATTTCTAGAACCATTTCTGAACAATTATTCCATTGTAGAAATTGGAGTACAACGGCAACCATTGGAGACAGAAGAAATTATACAAATTCTAGAGATTTATAAAAGATTTCCACACTTGTGGAACACAAATCTCGTAGAAAATGTCTGCACAAATAAACGCGACGAAGCTCTAAGTCAAATGATCGAGGCCTTACAGTCAGAATTATCATTGCAGGTGGATGATGTAGCCCTCAAGAAGTATTTGTACTGCATCCATGGCCACTTTACCACCGAGAAGGCCAAAATGCTGCACAAGAAAACATCGCCCAAAGACATATCGATATATTACGAGCATATGTTGTTTTTAGATGAGCATGTTGGCCCCTTCTATTGTTCGGAGTGTGGCAAAAAACATAAGAATCCTCTGCAGTTAAAAGTACATGAATCTCTGTCACATGGTCTGGAACCTTTAAAGTGTCCTCTCTGTGTCAAAACCTATACCAATGTTCAGGCTTATACATTTCATGCCCGACGACATATGAACGATACCAGTGAAGTGTGTAGAGTTTGTgggaaaacatttataaaagttgtagATCTTACAGCCCACATGCGTGGACACAATGGCATTAAGCCATATTTCTGTGAAATATGTGGCTCTTCGTTTACTATGCCATCGTCATTGACCGAACACAAGAAGCGACACAGTGCCCAAAATAAAGAACATTGTTCAATTTGTTCCAAGGCGTTCTTTAGCAAACGAAGATTAAATATGCATCTGTTAACACATTCAAATTCGAGAAGTTTCGTTTGCAACATCTGTGGAAAGGcctttaaaactaaaaaaacaatgCGAGCCCACGAAACAATACATGAAGATAGCCGCAATCATCCATGTACACTTTGcggtaaaatgtttaaaaatagaatTGGTGTTACGCAGCATTTGAGAACGCACCGAAATAATGCCGATACAGCATCAAATCCTTTTATTGGTAGTTGA
Protein Sequence: MDDVVKLEYLVCGEILAPISVNAKEQFFLKCLECDEYFTMLEEFIMHYQYCHNDKFKMTMHSPDTSNAQYQREVDIQYADECQEDRDIHEENDVEEVKDENEENYEAEYALVNESQDNIDEDFGEEEVHNFKDSEGEDGSGDDDNEIGDNEIDDNEVDEDAEIEMYDEENDKADDDDELLQDADDSQEEYDDEGSQDFDRIETSNNDDEDPLAHTHKEEIKKARAFVSKFLECDDNWKAFMRAYEKVPQLWDPKLFPKKLNNDERNAYLQKIANEIKSERNIELDTNLVGLTTVRVRQHFRIRINRFKTAEDRHDAIENKIVPKWYFEAYAFLELTLEQLSIVNFDSQRKHLRKEQILQIIQIYQRFPNLWNTNLAENVCFNKRQEALGEMSQVIRREMGLTIKETSLRKYLQSLHVHFAKEKSLLLDNQDKKPESELLYYDHMKYLNDHVGPLMCEFCGRKHKSPLFLKVHIYESHHRDDPLRCPICSKEYEHVQPYVAHARRHMDDLQDECKECGKRFIRLADLRTHMRTHTGVRPFFCDVCGASFTKRYSLTEHSRRHEKVYKFFCDICSKGFYERAKMNRHKICHSDIRKYCCSICGKAFKTRRHTKIHESTHADSREFPCPLCGKLFKNKIGVTHHLRTHRKNMETVLSPFTMDPLEKTLQGTNSNNDVCHAEKSIEKTFSDCGDELMGEHSKSFVKEFLKCDLNYKAILFAYQNQPSLWNRNLFPNKLNNDERNLCLKNIALELKTARNIELDTSMVTRHTYCVKLRRYKTIEQRKAAERNKIVPGWYFKQLAFLQPMMDHFTITKLDSQRTNLTKEQIIQILEIYKNFPVLWNTSLVENVCSNKRQEALERMLKPIHKEMGLKINVSILQQYLDSIHAHLSKEKTMLLKNNKNNENISMYYDHMKFLHDHVGPFCCGICGRRNRSPLHLKVHIYQKHNRNDPLRCPMCNKIYQQMEPYVAHARRHMNDLRVECKECGMFIRHADLRVHMYTHTGIKSYCCEVCGSVFTTASALVDHKRRHEKLYKVFCEICSKGFYYDEKLREHMTTHTNIRNYACGICGKKFKAKKTLKAHKSTHEEGLMEEYIEYILCGEILVAPAIDSKDQYCLKCNECSEYYSTLDEFIAHHQSDHSVDDLENISSSPASEVECNEEYLEIYSPLSVKAEHSNDGCEVAPPLSPTSYSETQTHDKNMDDGSTKSEIDDEEGFKGFESEGMAGDDETDPLDQPQCERTEDPINDEDNDNACFESEAEWEPEDNKTKVFVSQFLKCEKNFLTFIEAYKKQPRLWNWKQYPSKLNSSKEREKYWSQIAAEIRNNLNIEITCKYVSAVIRRIRNGYAIKLNRLKSYEQRGGTLKSRNIPQWYFNKMQFLEPFLNNYSIVEIGVQRQPLETEEIIQILEIYKRFPHLWNTNLVENVCTNKRDEALSQMIEALQSELSLQVDDVALKKYLYCIHGHFTTEKAKMLHKKTSPKDISIYYEHMLFLDEHVGPFYCSECGKKHKNPLQLKVHESLSHGLEPLKCPLCVKTYTNVQAYTFHARRHMNDTSEVCRVCGKTFIKVVDLTAHMRGHNGIKPYFCEICGSSFTMPSSLTEHKKRHSAQNKEHCSICSKAFFSKRRLNMHLLTHSNSRSFVCNICGKAFKTKKTMRAHETIHEDSRNHPCTLCGKMFKNRIGVTQHLRTHRNNADTASNPFIGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -