Basic Information

Insect: Musca domestica
Gene Symbol: -
Assembly: GCA_000371365.1
Location: Scaffold18839:194073-199870[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00015 0.0073 16.4 0.5 2 23 221 243 220 243 0.95

2 16 4.9e-05 0.0024 17.9 5.9 2 23 251 273 250 273 0.96

3 16 0.00092 0.046 13.9 4.9 1 23 289 312 289 312 0.96

4 16 6.5e-06 0.00032 20.7 1.8 3 23 338 358 337 358 0.99

5 16 0.00091 0.045 13.9 3.7 1 23 364 386 364 386 0.98

6 16 1.3e-05 0.00064 19.7 2.0 1 23 392 414 392 414 0.99

7 16 1.4e-05 0.00072 19.6 2.2 1 23 420 442 420 442 0.98

8 16 4e-05 0.002 18.2 1.4 1 23 448 472 448 472 0.91

9 16 2.2e-05 0.0011 19.0 0.9 2 23 712 734 711 734 0.95

10 16 0.00012 0.0061 16.6 4.7 2 23 742 764 741 764 0.95

11 16 0.0099 0.49 10.6 4.7 1 23 780 803 780 803 0.95

12 16 5.7e-05 0.0028 17.7 0.7 3 23 831 851 830 851 0.98

13 16 1.3e-06 6.5e-05 22.8 0.6 1 23 857 879 857 879 0.99

14 16 5.3e-06 0.00026 20.9 1.5 1 23 885 907 885 907 0.99

15 16 1.1e-05 0.00056 19.9 3.2 1 23 913 935 913 935 0.99

16 16 0.00014 0.0068 16.5 2.1 1 23 941 965 941 965 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00015	0.0073	16.4	0.5	2	23	221	243	220	243	0.95
2	16	4.9e-05	0.0024	17.9	5.9	2	23	251	273	250	273	0.96
3	16	0.00092	0.046	13.9	4.9	1	23	289	312	289	312	0.96
4	16	6.5e-06	0.00032	20.7	1.8	3	23	338	358	337	358	0.99
5	16	0.00091	0.045	13.9	3.7	1	23	364	386	364	386	0.98
6	16	1.3e-05	0.00064	19.7	2.0	1	23	392	414	392	414	0.99
7	16	1.4e-05	0.00072	19.6	2.2	1	23	420	442	420	442	0.98
8	16	4e-05	0.002	18.2	1.4	1	23	448	472	448	472	0.91
9	16	2.2e-05	0.0011	19.0	0.9	2	23	712	734	711	734	0.95
10	16	0.00012	0.0061	16.6	4.7	2	23	742	764	741	764	0.95
11	16	0.0099	0.49	10.6	4.7	1	23	780	803	780	803	0.95
12	16	5.7e-05	0.0028	17.7	0.7	3	23	831	851	830	851	0.98
13	16	1.3e-06	6.5e-05	22.8	0.6	1	23	857	879	857	879	0.99
14	16	5.3e-06	0.00026	20.9	1.5	1	23	885	907	885	907	0.99
15	16	1.1e-05	0.00056	19.9	3.2	1	23	913	935	913	935	0.99
16	16	0.00014	0.0068	16.5	2.1	1	23	941	965	941	965	0.91

Sequence Information

Coding Sequence: ATGGCCATTGAGGAGGAGTCGCCATCAAGGGAATTAAGCTATGGTGAACTCTTGAAGGAAGTTATAAATATAAGTATGGAGGATATCGAATGCACGGAAATGCCTCAATTTATCTGTGCCTGCTGTTCACGTAAACTCAAGTCATCCCACGCTTTCATAAGACAGGCCAAGGAGAGCCATGAAATTTTAATGTCCACGTTGAAAAAAGATGGCATGGATGAAACATCTACCCTGGATTGTCTACAGGAATCACAAATTGATATAGAAAAGTGTctggaaataaaaatggaaagcgCTGACGACAACGAAGATGATGTGGTGAACAAGGAAATGGACAGTGTTCGATGCAACAAGACTGAAATAGACATTTGCCGAAATCCAGTTGATTCAGTCCCACCTAAAGATGAGGAAAATGTAAAAGTCCCCTCTGGCGAAATTGAAGATGAAATACCCATACCCAATGATGACATTGACTTTGATTCGGATTCATCGAAAATGAACGGAGCAGACTTTTCCGATAGTGACTGCAATAACGAAGACGACGAAGTAGATCCCAATTGGCTGGCAAAGACTGACACGACTTCCGCTAGTGATAACCTCACGgggaaaaagaaaagaacatCAAAAATAAGAGAATCATTGGAAGAAGCCATTGCAGTGCCATGTACccagtgcaaaaaaatatttacaaatgccAAAGTATTGGCCAGACATCTAAGGAATACTCATGTACCCGAAGAACAGAAGTGTTCATGTCCCTTGTGTGGTATAAAATTTACACGTTCATGTAATATGTTCAAACATATGCGTACCCAACATGATCCGGATACAGTGAAAAATCTCCTACCGGCCAGTGAAAAAATGCATCAATGTGATAAATGTCCACAGAAATATGCCAAAAAGAAACATCTGAATAATCACATCAAGGCAAAACATAGTAATGACCAGGAGGCGGGCGAAAATTCTGATGAGGcagataataaaaacaacaaagcgGAAGATCGTTCATTGTGTTCCATATGTGGTTGTTCGTTTTCCAAAAAAGCATATCTTATTGTTCACATGAGAAAACATACGGGAGAACGACCGTTCCAGTGTGATTTATGTGAGCGGGCATTTGCCCACAACTCTGAATTGAAATGTCATCGACGCATCCATACCGGTGAGAAACCATACAAATGTAAGCTGTGCGAGAAGGCCTTTAGGGTGTATAAAAAACTTGCCACCCATATGCGTTCTCATACCGACGAACGACCCTATAAATGTAATCAATGTGAGAgaagttttaaatattcaaaagatCTAAATATTCACAATCGAATACATACCGGCGAAAGACCGTATTGTTGTCCAGTGTGTGGCAGTACTTTCACACAAAGTAATTCTCTGAAAGCTCATCGCATGAAATTGGGTCACATGGATGATAATGTAGCAACAACAGCGCCAAGTGCCGGTGCATCGTCATCCGTAACAAGTACATCAGCACCAGCGTCATCATCAGTCCCATCATCAATAAATCATTTACTATCATATGATTTAGAATCCCTTgaagaaattgttgttattgacCAATCCCTGTCGCTATCATATGCCCAACTATTGAAGGATGTAACAAGTATTAATGTGTTGGCCGATGCAGATTCAGCCATAATGCCAAAATCTATTTGCCAATCTTGCTCGGAGAAACTCAAACAATCCCATGGATTTATAAAACAAGCCTGGTCGGCCAATGAACAATTACAGAGCTTACTAAAGAGCTCTGAAACATTAGATTGCTTACAAGAGTCTGAAATTGATATAAATAGCTGTTTGGAAATAAAACTAGAAAATAATGAAGACCTGGTGAACGACAAGAAGGTAACGCCCGGAAAAGATGATAAAGGGTGCAATTTGGCAGATAATTTAAATACCATTGAGGACAGCAATAGAGATGACTCAATCTTCAGCCCAGAGATGGAGGATAGTTTAGCAAAAACCGAATCTGATATTTCGGAAAATACGAATGCTAATGAGGAGCTGTTAACATCTGATGCCATTAAGGaaaaatcgaaaccaaaatcaaatacaaaaaataaaaaaccctcCACCAAGAGATTAGAAAGCAAAGATATCAAGGATGAAGACATTGCAGTGCCATGTTTACAGTGCaataagatttttaataattccaaaGAATTGACAAGACATCTGCGCAACACCCACCTGCCGGAGGATCAAAAATGTGCTTGTCCCTTGTGTGGCATAAAGTTTACACGTTCCTGTAACATGTACAAACACATGCGTAAGCTACACGATCCAGAATCGGTCAAGTCTTTGTTGCCCACTAAAGAGAAACCCTTTGAATGTGATAAATGTCATCGTCGATATACACAACAGCGTCAATTGAACTTCCACATTAAAGAGAAACATTCAAATGACCCAGATAATACCCAGGACTCCAACTCGAGCAATTGCAATGATAAGAAGAAAAAGCCGGATGTACGACCCCTGTGTTTTGTATGTGGCAGCTCATTTTCTAATAAAGCCCATCTAATTGTCCACATGGCAAGACACACGGGTGAAAAACCCTTCAAATGTGATCTTTGTGATAGAGCCTTTCCTCGTACATCCGATTTGACGTCACATCGTCGCATACATACGGGTGAAAAACCATTTAAGTGCAAATTGTGTGAAAAGGCTTTTCGTGTCTCAACAAAATTAGCAACACACATGCGTTCCCATACCAATGAACGACCCTTTAAATGTAAACAATGCGAAAgaagttttaaatattccaaagatTTGAATATACACAAACGGGTGCATACCGGAGAACGACCTTATTGTTGTACTGTCTGCGGCAGTACATTTACACAGAGTAATTCGTTAAAAGCCCATCGTATGAAATTGGGTCACATGGGGGTGCAGGAGGAGCCAACGTCACAAATAATGCATTTTATTAGTTga
Protein Sequence: MAIEEESPSRELSYGELLKEVINISMEDIECTEMPQFICACCSRKLKSSHAFIRQAKESHEILMSTLKKDGMDETSTLDCLQESQIDIEKCLEIKMESADDNEDDVVNKEMDSVRCNKTEIDICRNPVDSVPPKDEENVKVPSGEIEDEIPIPNDDIDFDSDSSKMNGADFSDSDCNNEDDEVDPNWLAKTDTTSASDNLTGKKKRTSKIRESLEEAIAVPCTQCKKIFTNAKVLARHLRNTHVPEEQKCSCPLCGIKFTRSCNMFKHMRTQHDPDTVKNLLPASEKMHQCDKCPQKYAKKKHLNNHIKAKHSNDQEAGENSDEADNKNNKAEDRSLCSICGCSFSKKAYLIVHMRKHTGERPFQCDLCERAFAHNSELKCHRRIHTGEKPYKCKLCEKAFRVYKKLATHMRSHTDERPYKCNQCERSFKYSKDLNIHNRIHTGERPYCCPVCGSTFTQSNSLKAHRMKLGHMDDNVATTAPSAGASSSVTSTSAPASSSVPSSINHLLSYDLESLEEIVVIDQSLSLSYAQLLKDVTSINVLADADSAIMPKSICQSCSEKLKQSHGFIKQAWSANEQLQSLLKSSETLDCLQESEIDINSCLEIKLENNEDLVNDKKVTPGKDDKGCNLADNLNTIEDSNRDDSIFSPEMEDSLAKTESDISENTNANEELLTSDAIKEKSKPKSNTKNKKPSTKRLESKDIKDEDIAVPCLQCNKIFNNSKELTRHLRNTHLPEDQKCACPLCGIKFTRSCNMYKHMRKLHDPESVKSLLPTKEKPFECDKCHRRYTQQRQLNFHIKEKHSNDPDNTQDSNSSNCNDKKKKPDVRPLCFVCGSSFSNKAHLIVHMARHTGEKPFKCDLCDRAFPRTSDLTSHRRIHTGEKPFKCKLCEKAFRVSTKLATHMRSHTNERPFKCKQCERSFKYSKDLNIHKRVHTGERPYCCTVCGSTFTQSNSLKAHRMKLGHMGVQEEPTSQIMHFIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -