Mdom012306.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Musca domestica
Gene Symbol
Zfy1
Assembly
GCA_000371365.1
Location
Scaffold1623:8883-12645[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 4.8e-06 0.00024 21.1 0.8 1 23 213 235 213 235 0.98
2 15 0.00046 0.023 14.8 0.8 1 23 241 264 241 264 0.96
3 15 0.0011 0.055 13.6 0.3 1 23 274 296 274 296 0.97
4 15 2.1e-05 0.001 19.0 0.3 1 20 430 449 430 452 0.93
5 15 4.7e-05 0.0023 17.9 0.8 1 23 458 480 458 480 0.95
6 15 3.4e-06 0.00017 21.5 0.3 1 23 497 519 497 519 0.98
7 15 0.0044 0.22 11.7 0.4 1 23 528 551 528 551 0.95
8 15 0.0023 0.11 12.6 5.2 1 23 557 579 557 579 0.98
9 15 0.00015 0.0075 16.4 0.4 2 23 586 607 585 607 0.97
10 15 1.9e-08 9.2e-07 28.7 0.7 1 23 613 635 613 635 0.96
11 15 0.01 0.52 10.6 5.3 1 23 641 663 641 663 0.99
12 15 6.2e-05 0.0031 17.6 2.3 1 23 669 691 669 691 0.96
13 15 3.8e-06 0.00019 21.4 2.6 1 23 697 719 697 719 0.99
14 15 5.2e-07 2.6e-05 24.1 0.7 1 23 725 747 725 747 0.99
15 15 7.1e-06 0.00035 20.5 1.1 1 23 753 775 753 775 0.97

Sequence Information

Coding Sequence
ATGTCTCCGTCAAAGCTAAGAAAATGCCGTACATGTTTAAGTGAGAATGAAAATGACACCTACCTTCAACTTGTCGATTACATTGAAGAAGAGGAGGCTAAAATCATTGATATGCTGGATGAGATTGTACCAGAAATAAAAGTCAAGGAGGAGACCCAACTGTCTCGATATATTTGTCAAGATTGTGTTGACAAATTGCTAACGGGACACAGATTCCAGCAGCTATGCATAGAATCAAATAAGCATCTGCTGGCATGCCTCAACAATTTGGAATCTAAGGGAGCCAATGATGCGGAGCAAAAAGAGGAAATTGCTAATGAGGAGCTGGATCCTGATCCTCTGACAGCTGAAGTTGACTTAAAGTTAAAACAAGAACTAGAGATTAGTGATACATATAAGTCAGACATAAGTACAAAGGAATTAGAAAATAGTTTGAACTCGGATAGTGATTGGGGAGAGGATGGGGTGGATGCCAAGGCAAGTGTTACGGAGGAAAATGATAGCGGCAGTGACACAGATTCCagCAATGAGAAGCTGTCGGTGTTAAAGCAAAGAAGGTTGCAAAAGACTAAAAATCAGAATAAGGATGGCGAAAGGAAACGCGGGAAACCCGGAAGAAAATCAAAAGGTCCACCTTATCCCTGTACTGTTTGTGGCAAATTATTGACTACTCCGTCGCATTTACAACGACACAGCCGAGTACATGAACTGAATCGTGCATTTCCCTGTGATATTTGCAAATTGAGTTTTGCCAAGGAGAAGACCTACCGGTCCCACATGCAGCTAAATCACAAGGAGATGTTTGATAAGGGCGAAGAATTTGAATGTCCTATTTGTTCGAAAacgttttggaaaaaattatcgcTATCCCAACACATGGTCATCCATAATCCGAATGCCAAAAAACGGGGAAGGCCATTgggtaaattaaacaaaatcaaGGAAGAGGATAATCCAGAGGAAAtgcaaaatgaaaacaagaagACCCCGTCCTCCAGTGGTGATAAGTTATTGGAATCAAATTCCAATGAAATGGCTGCCGTTGATGGTGTAAaacatgaaattgaaattacCCCTCAAATATTCGATGCGTTGGAGGATTATGATGAGCCCAATGATGAGTGGTTTGATCAGGATGGGGTATATGAGGATACAGACGATGAGGAAGAAGAAGGCACTGGAAAAGAACGACGCCCCAAACCCGTATATAATCCAGATATGGATTTTGTGGATACGGGTATTGGAGAAGTTGAAAAACCCAGTGCACGTAACCGTCGAAATGGCAACTTCCCCTGTGGGGTTTGTGGTAAATTCTTTGACCGCCCATACCGTCTAAAACGCCACATGCCAGTACATTCCATGGACCGACCACATGCCTGTAATATCTGTAAATATCGCTTTGTCACCCCCAACCTGCTGAGGATCCATATGATACAACATGAAAATGACAATGCCACAACTTTTATGATGCAAACTCGGCCGGATGGCTTCAAATGTCCCGACTGTCCAAggcgttttgaaaaacaagccTCCCTCTCGGCCCACCGTCAAATTCACACGCGCAACACCTCCGAAGTTAATTACCCCTGCACGGTGTGTGAACGTAATTTCATGTCTGTGCGTTCCCTAACCGAACACATCACCAACAAACACCCCGAGGTGGAGAAACATAAATGTGATCAATGTGAAAAGACTTTTGTACTACATGCCCATCTGCTGGAGCATTTGAACCGACACAAGGGTAATAAGAATTTGGTGTGTCTCATTTGTGAAAAGGAATTTGGTTACACCAACACACTGAAAGAGCATATGCGCACCCATAGTGGTGAATCTCCCTATCTTTGTCCACAGTGTGGTAAAACCTTTAGGAGTGCCAGTAATTTGAGGCAACACATGGAACGACATTTTGGTCTGAAGAAATATCAATGTCCGGAGTGTCCAAGTCGTTTTAATTGTCGTTCGGATTTGTGCAAACACACATCGACGCACACGAATGCCAAACCTCATGTTTGTGATGTATGTGGTTCACGTTTTACCCGATCCTATTCCTTGCAGAAACACAAGCTGCTTCATTCGGGAGAGAGGCCATTTAAATGTGATGAGTGTAACATGACCTTTGCCATAGTATATCATTTGCGTAGGCACATGCGCACGCACACCGGCGAGAAAccatataaatgtaaatattgtgaTCGTGCCTATGCCGAAAGTGGAGATTTGACCAAACATTTGAGAACGCATGTTGGTGAAAATACCTACATGTGTACCGAATGTCCAATGGCTTTTAAATATCAATCAGAACTGCGTCATCACATATCGGAACATTATAAAAGTTCCCAACAATCGTTGGCACAACAAACGCAGGAAGTCCCCAATGAACAGGCTCAAGAATTTGCAAAAGAAGAACCACAAAATGTGCAAAATGATTTGCAATTAACAGAAGAATCTCATCCCTCGTTGCAATTACCAATGCTAGAAGCTACAACTACCTGTCATACAACAGGCAGCGAACAGTTAATGTTATCCATGGCAAGTTCTTCAAATCACACATCTTCTCCTGTAGCTAGTTAA
Protein Sequence
MSPSKLRKCRTCLSENENDTYLQLVDYIEEEEAKIIDMLDEIVPEIKVKEETQLSRYICQDCVDKLLTGHRFQQLCIESNKHLLACLNNLESKGANDAEQKEEIANEELDPDPLTAEVDLKLKQELEISDTYKSDISTKELENSLNSDSDWGEDGVDAKASVTEENDSGSDTDSSNEKLSVLKQRRLQKTKNQNKDGERKRGKPGRKSKGPPYPCTVCGKLLTTPSHLQRHSRVHELNRAFPCDICKLSFAKEKTYRSHMQLNHKEMFDKGEEFECPICSKTFWKKLSLSQHMVIHNPNAKKRGRPLGKLNKIKEEDNPEEMQNENKKTPSSSGDKLLESNSNEMAAVDGVKHEIEITPQIFDALEDYDEPNDEWFDQDGVYEDTDDEEEEGTGKERRPKPVYNPDMDFVDTGIGEVEKPSARNRRNGNFPCGVCGKFFDRPYRLKRHMPVHSMDRPHACNICKYRFVTPNLLRIHMIQHENDNATTFMMQTRPDGFKCPDCPRRFEKQASLSAHRQIHTRNTSEVNYPCTVCERNFMSVRSLTEHITNKHPEVEKHKCDQCEKTFVLHAHLLEHLNRHKGNKNLVCLICEKEFGYTNTLKEHMRTHSGESPYLCPQCGKTFRSASNLRQHMERHFGLKKYQCPECPSRFNCRSDLCKHTSTHTNAKPHVCDVCGSRFTRSYSLQKHKLLHSGERPFKCDECNMTFAIVYHLRRHMRTHTGEKPYKCKYCDRAYAESGDLTKHLRTHVGENTYMCTECPMAFKYQSELRHHISEHYKSSQQSLAQQTQEVPNEQAQEFAKEEPQNVQNDLQLTEESHPSLQLPMLEATTTCHTTGSEQLMLSMASSSNHTSSPVAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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